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Volumn 134, Issue 4, 2011, Pages 459-468

1,25-Dihydroxyvitamin D 3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells

Author keywords

1,25 dihydroxyvitamin D 3; Cholecalciferol; Forkhead box protein 3; HIV; Immunomodulation; Regulatory T cells

Indexed keywords

CALCITRIOL; COLECALCIFEROL; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; VITAMIN D RECEPTOR;

EID: 80355142089     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2011.03507.x     Document Type: Article
Times cited : (57)

References (40)
  • 1
    • 33744784615 scopus 로고    scopus 로고
    • Vitamin D physiology
    • Lips P. Vitamin D physiology. Prog Biophys Mol Biol 2006; 92:4-8.
    • (2006) Prog Biophys Mol Biol , vol.92 , pp. 4-8
    • Lips, P.1
  • 2
    • 0043270561 scopus 로고    scopus 로고
    • The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells
    • Mahon BD, Wittke A, Weaver V, Cantorna MT. The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells. J Cell Biochem 2003; 89:922-32.
    • (2003) J Cell Biochem , vol.89 , pp. 922-932
    • Mahon, B.D.1    Wittke, A.2    Weaver, V.3    Cantorna, M.T.4
  • 4
    • 0038189866 scopus 로고    scopus 로고
    • Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells
    • Hewison M, Freeman L, Hughes SV et al. Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells. J Immunol 2003; 170:5382-90.
    • (2003) J Immunol , vol.170 , pp. 5382-5390
    • Hewison, M.1    Freeman, L.2    Hughes, S.V.3
  • 5
    • 34247890248 scopus 로고    scopus 로고
    • DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27
    • Sigmundsdottir H, Pan J, Debes GF et al. DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27. Nat Immunol 2007; 8:285-93.
    • (2007) Nat Immunol , vol.8 , pp. 285-293
    • Sigmundsdottir, H.1    Pan, J.2    Debes, G.F.3
  • 6
    • 27544499686 scopus 로고    scopus 로고
    • Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts
    • van EE, Mathieu C. Immunoregulation by 1, 25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol 2005; 97:93-101.
    • (2005) J Steroid Biochem Mol Biol , vol.97 , pp. 93-101
    • van, E.E.1    Mathieu, C.2
  • 7
    • 0035204814 scopus 로고    scopus 로고
    • Vitamin D: its role and uses in immunology
    • Deluca HF, Cantorna MT. Vitamin D: its role and uses in immunology. FASEB J 2001; 15:2579-85.
    • (2001) FASEB J , vol.15 , pp. 2579-2585
    • Deluca, H.F.1    Cantorna, M.T.2
  • 8
  • 9
    • 48749085956 scopus 로고    scopus 로고
    • Control of autoimmune diseases by the vitamin D endocrine system
    • Adorini L, Penna G. Control of autoimmune diseases by the vitamin D endocrine system. Nat Clin Pract Rheumatol 2008; 4:404-12.
    • (2008) Nat Clin Pract Rheumatol , vol.4 , pp. 404-412
    • Adorini, L.1    Penna, G.2
  • 10
    • 33744826596 scopus 로고    scopus 로고
    • Vitamin D and its role in immunology: multiple sclerosis, and inflammatory bowel disease
    • Cantorna MT. Vitamin D and its role in immunology: multiple sclerosis, and inflammatory bowel disease. Prog Biophys Mol Biol 2006; 92:60-4.
    • (2006) Prog Biophys Mol Biol , vol.92 , pp. 60-64
    • Cantorna, M.T.1
  • 11
    • 15444380329 scopus 로고    scopus 로고
    • 3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice
    • 3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice. Endocrinology 2005; 146:1956-64.
    • (2005) Endocrinology , vol.146 , pp. 1956-1964
    • Gysemans, C.A.1    Cardozo, A.K.2    Callewaert, H.3
  • 12
    • 33744803244 scopus 로고    scopus 로고
    • Vitamin D: its role in cancer prevention and treatment
    • Holick MF. Vitamin D: its role in cancer prevention and treatment. Prog Biophys Mol Biol 2006; 92:49-59.
    • (2006) Prog Biophys Mol Biol , vol.92 , pp. 49-59
    • Holick, M.F.1
  • 13
    • 33745452857 scopus 로고    scopus 로고
    • A potential role for vitamin D on HIV infection?
    • Villamor E. A potential role for vitamin D on HIV infection? Nutr Rev 2006; 64:226-33.
    • (2006) Nutr Rev , vol.64 , pp. 226-233
    • Villamor, E.1
  • 14
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol 2001; 2:816-22.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 15
    • 33746342994 scopus 로고    scopus 로고
    • + natural regulatory T cells in dominant self-tolerance and autoimmune disease
    • + natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006; 212:8-27.
    • (2006) Immunol Rev , vol.212 , pp. 8-27
    • Sakaguchi, S.1    Ono, M.2    Setoguchi, R.3
  • 16
    • 0141461418 scopus 로고    scopus 로고
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med 2003; 9:1144-50.
    • (2003) Nat Med , vol.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3
  • 18
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3:199-210.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 19
    • 0034178251 scopus 로고    scopus 로고
    • Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells
    • Piemonti L, Monti P, Sironi M et al. Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. J Immunol 2000; 164:4443-51.
    • (2000) J Immunol , vol.164 , pp. 4443-4451
    • Piemonti, L.1    Monti, P.2    Sironi, M.3
  • 20
    • 65049086842 scopus 로고    scopus 로고
    • Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists
    • Adorini L, Penna G. Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists. Hum Immunol 2009; 70:345-52.
    • (2009) Hum Immunol , vol.70 , pp. 345-352
    • Adorini, L.1    Penna, G.2
  • 21
    • 0037018104 scopus 로고    scopus 로고
    • + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 2002; 195:603-16.
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3
  • 23
    • 77951253745 scopus 로고    scopus 로고
    • 3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3
    • 3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. J Immunol 2009; 183:5458-67.
    • (2009) J Immunol , vol.183 , pp. 5458-5467
    • Jeffery, L.E.1    Burke, F.2    Mura, M.3
  • 26
    • 68049101203 scopus 로고    scopus 로고
    • Peripheral blood regulatory T cell measurements correlate with serum vitamin D levels in patients with multiple sclerosis
    • Royal W III, Mia Y, Li H, Naunton K. Peripheral blood regulatory T cell measurements correlate with serum vitamin D levels in patients with multiple sclerosis. J Neuroimmunol 2009; 213:135-41.
    • (2009) J Neuroimmunol , vol.213 , pp. 135-141
    • Royal III, W.1    Mia, Y.2    Li, H.3    Naunton, K.4
  • 27
    • 68949140898 scopus 로고    scopus 로고
    • Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis
    • Smolders J, Thewissen M, Peelen E et al. Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis. PLoS ONE 2009; 4:e6635.
    • (2009) PLoS ONE , vol.4
    • Smolders, J.1    Thewissen, M.2    Peelen, E.3
  • 28
    • 0035881234 scopus 로고    scopus 로고
    • Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
    • Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, Adorini L. Regulatory T cells induced by 1 alpha, 25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 2001; 167:1945-53.
    • (2001) J Immunol , vol.167 , pp. 1945-1953
    • Gregori, S.1    Casorati, M.2    Amuchastegui, S.3    Smiroldo, S.4    Davalli, A.M.5    Adorini, L.6
  • 29
    • 37349104972 scopus 로고    scopus 로고
    • Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile
    • Daniel C, Sartory NA, Zahn N, Radeke HH, Stein JM. Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile. J Pharmacol Exp Ther 2008; 324:23-33.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 23-33
    • Daniel, C.1    Sartory, N.A.2    Zahn, N.3    Radeke, H.H.4    Stein, J.M.5
  • 31
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G, Adorini L. 1 Alpha, 25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 2000; 164:2405-11.
    • (2000) J Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 32
    • 0021678081 scopus 로고
    • Inhibition of T lymphocyte mitogenesis by 1,25-dihydroxyvitamin D3 (calcitriol)
    • Rigby WF, Stacy T, Fanger MW. Inhibition of T lymphocyte mitogenesis by 1, 25-dihydroxyvitamin D3 (calcitriol). J Clin Invest 1984; 74:1451-5.
    • (1984) J Clin Invest , vol.74 , pp. 1451-1455
    • Rigby, W.F.1    Stacy, T.2    Fanger, M.W.3
  • 33
    • 0022256520 scopus 로고
    • 1,25-Dihydroxyvitamin D3 suppresses human T helper/inducer lymphocyte activity in vitro
    • Lemire JM, Adams JS, Kermani-Arab V, Bakke AC, Sakai R, Jordan SC. 1, 25-Dihydroxyvitamin D3 suppresses human T helper/inducer lymphocyte activity in vitro. J Immunol 1985; 134:3032-5.
    • (1985) J Immunol , vol.134 , pp. 3032-3035
    • Lemire, J.M.1    Adams, J.S.2    Kermani-Arab, V.3    Bakke, A.C.4    Sakai, R.5    Jordan, S.C.6
  • 34
    • 0027537655 scopus 로고
    • 1,25-dihydroxyvitamin D3 selectively reduces interleukin-2 levels and proliferation of human T cell lines in vitro
    • Muller K, Odum N, Bendtzen K. 1, 25-dihydroxyvitamin D3 selectively reduces interleukin-2 levels and proliferation of human T cell lines in vitro. Immunol Lett 1993; 35:177-82.
    • (1993) Immunol Lett , vol.35 , pp. 177-182
    • Muller, K.1    Odum, N.2    Bendtzen, K.3
  • 36
    • 0023267970 scopus 로고
    • Regulation of lymphokine production and human T lymphocyte activation by 1,25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA
    • Rigby WF, Denome S, Fanger MW. Regulation of lymphokine production and human T lymphocyte activation by 1, 25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA. J Clin Invest 1987; 79:1659-64.
    • (1987) J Clin Invest , vol.79 , pp. 1659-1664
    • Rigby, W.F.1    Denome, S.2    Fanger, M.W.3
  • 38
    • 10044281540 scopus 로고    scopus 로고
    • Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence
    • Cantorna MT, Mahon BD. Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence. Exp Biol Med (Maywood) 2004; 229:1136-42.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 1136-1142
    • Cantorna, M.T.1    Mahon, B.D.2
  • 39
    • 33645031366 scopus 로고    scopus 로고
    • Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity
    • Imazeki I, Matsuzaki J, Tsuji K, Nishimura T. Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity. Biomed Res 2006; 27:1-9.
    • (2006) Biomed Res , vol.27 , pp. 1-9
    • Imazeki, I.1    Matsuzaki, J.2    Tsuji, K.3    Nishimura, T.4
  • 40
    • 53249137958 scopus 로고    scopus 로고
    • Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy
    • Tran TA, de Goer de Herve MG, Hendel-Chavez H et al. Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy. PLoS ONE 2008; 3:e3305.
    • (2008) PLoS ONE , vol.3
    • Tran, T.A.1    de Goer de Herve, M.G.2    Hendel-Chavez, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.