A potential role for vitamin D on HIV infection?

Nutrition Reviews

Volumn 64, Issue 5, 2006, Pages 226-233

  Villamor, Eduardo ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Deficiency; HIV; Vitamin D; Vitamin D receptor

Indexed keywords

CALCIFEDIOL; VITAMIN D; VITAMIN D RECEPTOR;

CELL COUNT; DIET; DISEASE COURSE; DISEASE PREDISPOSITION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MORTALITY; NUTRITIONAL STATUS; REVIEW; VITAMIN SUPPLEMENTATION;

CALCITRIOL; CD4 LYMPHOCYTE COUNT; DISEASE PROGRESSION; HEALTH STATUS; HIV INFECTIONS; HUMANS; NUTRITIONAL REQUIREMENTS; VITAMIN D; VITAMIN D DEFICIENCY; VITAMINS;

EID: 33745452857     PISSN: 00296643     EISSN: 00296643     Source Type: Journal    
DOI: 10.1301/nr.2006.may.226-233     Document Type: Review

References (76)

1. The Joint United Nations Programme on AIDS (UNAIDS). AIDS Epidemic Update. Geneva: World Health Organization; 2004.
2. Tang AM, Graham NM, Kirby AJ, McCall LD, Willett WC, Saah AJ. Dietary micronutrient intake and risk of progression to acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus type 1 (HIV-1)-infected homosexual men. Am J Epidemiol. 1993;138:937-951.
3. Baum MK, Shor-Posner G, Lu Y, et al. Micronutrients and HIV-1 disease progression. AIDS. 1995;9:1051-1056.
4. Tang AM, Graham NM, Saah AJ. Effects of micronutrient intake on survival in human immunodeficiency virus type 1 infection. Am J Epidemiol. 1996;143:1244-1256.
5. Baum MK, Shor-Posner G, Lai S, et al. High risk of HIV-related mortality is associated with selenium deficiency. J Acquir Immune Defic Syndr Hum Retrovirol. 1997;15:370-374.
6. Fawzi WW, Msamanga GI, Spiegelman D, et al. A randomized trial of multivitamin supplements and HIV disease progression and mortality. N Engl J Med. 2004;351:23-32.
7. McClelland RS, Baeten JM, Overbaugh J, et al. Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial. J Acquir Immune Defic Syndr. 2004;37:1657-1663.
8. Allard JP, Aghdassi E, Chau J, et al. Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects. AIDS. 1998;12:1653-1659.
9. Bhalla AK, Amento EP, Clemens TL, Holick MF, Krane SM. Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation. J Clin Endocrinol Metab. 1983;57:1308-1310.
10. Provvedini DM, Tsoukas CD, Deftos LJ, Manolagas SC. 1,25-dihydroxyvitamin D3 receptors in human leukocytes. Science. 1983;221:1181-1183.
11. Reinhardt TA, Horst RL, Littledike ET, Beitz DC. 1,25-Dihydroxyvitamin D3 receptor in bovine thymus gland. Biochem Biophys Res Commun. 1982;106:1012-1018.
12. Morgan JW, Morgan DM, Lasky SR, Ford D, Kouttab N, Maizel AL. Requirements for induction of vitamin D-mediated gene regulation in normal human B lymphocytes. J Immunol. 1996;157:2900-2908.
13. Brennan A, Katz DR, Nunn JD, et al. Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol. Immunology. 1987;61:457-461.
14. Salimpour R. Rickets in Tehran. Study of 200 cases. Arch Dis Child. 1975;50:63-66.
15. Lawson DE, Cole TJ, Salem SI, et al. Etiology of rickets in Egyptian children. Hum Nutr Clin Nutr. 1987;41:199-208.
16. Lubani MM, al-Shab TS, al-Saleh QA, et al. Vitamin-D-deficiency rickets in Kuwait: the prevalence of a preventable disease. Ann Trop Paediatr. 1989;9:134-139.
17. Lulseged S. Severe rickets in a children's hospital in Addis Ababa. Ethiop Med J. 1990;28:175-181.
18. Hortal M, Benitez A, Contera M, Etorena P, Montano A, Meny M. A community-based study of acute respiratory tract infections in children in Uruguay. Rev Infect Dis. 1990;12(suppl 8):S966-S973.
19. Banajeh SM, al-Sunbali NN, al-Sanahani SH. Clinical characteristics and outcome of children aged under 5 years hospitalized with severe pneumonia in Yemen. Ann Trop Paediatr. 1997;17:321-326.
20. Muhe L, Lulseged S, Mason KE, Simoes EA. Case-control study of the role of nutritional rickets in the risk of developing pneumonia in Ethiopian children. Lancet. 1997;349:1801-1804.
21. Wayse V, Yousafzai A, Mogale K, Filteau S. Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. Eur J Clin Nutr. 2004;58:563-567.
22. Davies PD, Brown RC, Woodhead JS. Serum concentrations of vitamin D metabolites in untreated tuberculosis. Thorax. 1985;40:187-190.
23. Cantorna MT, Zhu Y, Froicu M, Wittke A. Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr. 2004;80:1717S-1720S.
24. Hayes CE, Nashold FE, Spach KM, Pedersen LB. The immunological functions of the vitamin D endocrine system. Cell Mol Biol (Noisy-le-grand). 2003;49:277-300.
25. Griffin MD, Xing N, Kumar R. Vitamin D and its analogs as regulators of immune activation and antigen presentation. Annu Rev Nutr. 2003;23:117-145.
26. Bettica P, Bevilacqua M, Vago T, Norbiato G. High prevalence of hypovitaminosis D among free-living postmenopausal women referred to an osteoporosis outpatient clinic in northern Italy for initial screening. Osteoporos Int. 1999;9:226-229.
27. Lips P, Duong T, Oleksik A, et al. A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. J Clin Endocrinol Metab. 2001;86:1212-1221.
28. Calvo MS, Whiting SJ. Prevalence of vitamin D insufficiency in Canada and the United States: importance to health status and efficacy of current food fortification and dietary supplement use. Nutr Rev. 2003;61:107-113.
29. Hanley DA, Davison KS. Vitamin D insufficiency in North America. J Nutr. 2005;135:332-337.
30. Pettifor JM. Nutritional rickets: deficiency of vitamin D, calcium, or both? Am J Clin Nutr. 2004;80:1725S-1729S.
31. Hollis BW. Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. J Nutr. 2005;135:317-322.
32. Coodley GO, Coodley MK, Nelson HD, Loveless MO. Micronutrient concentrations in the HIV wasting syndrome. AIDS. 1993;7:1595-1600.
33. Kuehn EW, Anders HJ, Bogner JR, Obermaier J, Goebel FD, Schlondorff D. Hypocalcaemia in HIV infection and AIDS. J Intern Med. 1999;245:69-73.
34. Serrano S, Marinoso ML, Soriano JC, et al. Bone remodelling in human immunodeficiency virus-1-infected patients. A histomorphometric study. Bone. 1995;16:185-191.
35. O'Brien KO, Razavi M, Henderson RA, Caballero B, Ellis KJ. Bone mineral content in girls perinatally infected with HIV. Am J Clin Nutr. 2001;73:821-826.
36. Haug C, Muller F, Aukrust P, Froland SS. Subnormal serum concentration of 1,25-vitamin D in human immunodeficiency virus infection: correlation with degree of immune deficiency and survival. J Infect Dis. 1994;169:889-893.
37. Jaeger P, Otto S, Speck RF, et al. Altered parathyroid gland function in severely immunocompromised patients infected with human immunodeficiency virus. J Clin Endocrinol Metab. 1994;79:1701-1705.
38. Teichmann J, Stephan E, Discher T, et al. Changes in calciotropic hormones and biochemical markers of bone metabolism in patients with human immunodeficiency virus infection. Metabolism. 2000;49:1134-1139.
39. Teichmann J, Stephan E, Lange U, et al. Osteopenia in HIV-infected women prior to highly active antiretroviral therapy. J Infect. 2003;46:221-227.
40. Haug CJ, Aukrust P, Haug E, Morkrid L, Muller F, Froland SS. Severe deficiency of 1,25-dihydroxyvitamin D3 in human immunodeficiency virus infection: association with immunological hyperactivity and only minor changes in calcium homeostasis. J Clin Endocrinol Metab. 1998;83:3832-3838.
41. Haug CJ, Aukrust P, Lien E, Muller F, Espevik T, Froland SS. Disseminated Mycobacterium avium complex infection in AIDS: immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D. J Infect Dis. 1996;173:259-262.
42. Hanevold CD, Yamaguchi DT, Jordan SC. Tumor necrosis factor alpha modulates parathyroid hormone action in UMR-106-01 osteoblastic cells. J Bone Miner Res. 1993;8:1191-1200.
43. Madeddu G, Spanu A, Solinas P, et al. Bone mass loss and vitamin D metabolism impairment in HIV patients receiving highly active antiretroviral therapy. Q J Nucl Med. 2004;48:39-48.
44. Cozzolino M, Vidal M, Arcidiacono MV, Tebas P, Yarasheski KE, Dusso AS. HIV-protease inhibitors impair vitamin D bioactivation to 1,25-dihydroxyvitamin D. AIDS. 2003;17:513-520.
45. Glass AR, Eil C. Ketoconazole-induced reduction in serum 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab. 1986;63:766-769.
46. Ahmed B, Jaspan JB. Case report: hypercalcemia in a patient with AIDS and Pneumocystis carinii pneumonia. Am J Med Sci. 1993;306:313-316.
47. Delahunt JW, Romeril KE. Hypercalcemia in a patient with the acquired immunodeficiency syndrome and Mycobacterium avium intracellulare infection. J Acquir Immune Defic Syndr. 1994;7:871-872.
48. Aly ES, Baig M, Khanna D, Baumann MA. Hypercalcaemia: a clue to Mycobacterium avium intracellulare infection in a patient with AIDS. Int J Clin Pract. 1999;53:227-228.
49. Al-Tawfiq JA, Cushing HE. Hypercalcemia as an early sign of lymphoma in a patient with acquired immunodeficiency syndrome (AIDS). South Med J. 1999;92:924-926.
50. Adams JS, Fernandez M, Gacad MA, et al. Vitamin D metabolite-mediated hypercalcemia and hypercalciuria patients with AIDS- and non-AIDS-associated lymphoma. Blood. 1989;73:235-239.
51. Ali MY, Gopal KV, Llerena LA, Taylor HC. Hypercalcemia associated with infection by Cryptococcus neoformans and Coccidioides immitis. Am J Med Sci. 1999;318:419-423.
52. Besancon F, Just J, Bourgeade MF, et al. HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase. J Interferon Cytokine Res. 1997;17:461-467.
53. Kewenig S, Schneider T, Hohloch K, et al. Rapid mucosal CD4(+) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques. Gastroenterology. 1999;116:1115-1123.
54. Dannhauser A, van Staden AM, van der Ryst E, et al. Nutritional status of HIV-1 seropositive patients in the Free State Province of South Africa: anthropometric and dietary profile. Eur J Clin Nutr. 1999;53:165-173.
55. de Luis DA, Bachiller P, Aller R, et al. Relation among micronutrient intakes with CD4 count in HIV infected patients [in Spanish]. Nutr Hosp. 2002;17:285-289.
56. Girasole G, Wang JM, Pedrazzoni M, et al. Augmentation of monocyte chemotaxis by 1 alpha,25-dihydroxyvitamin D3. Stimulation of defective migration of AIDS patients. J Immunol. 1990;145:2459-2464.
57. Haug CJ, Muller F, Aukrust P, Froland SS. Different effect of 1,25-dihydroxyvitamin D3 on replication of Mycobacterium avium in monocyte-derived macrophages from human immunodeficiency virus-infected subjects and healthy controls. Immunol Lett. 1998;63:107-112.
58. Haug CJ, Muller F, Rollag H, Aukrust P, Degre M, Froland SS. The effect of 1,25-vitamin D3 on maturation of monocytes from HIV-infected patients varies with degree of immunodeficiency. Apmis. 1996;104:539-548.
59. Schlesinger M, Bar-Shavit Z, Hadar R, Rabinowitz R. Modulation of the expression of CD4 on HL-60 cells by exposure to 1,25-dihydroxyvitamin D3. Immunol Lett. 1989;22:307-311.
60. Rigby WF, Waugh M, Graziano RF. Regulation of human monocyte HLA-DR and CD4 antigen expression, and antigen presentation by 1,25-dihydroxyvitamin D3. Blood. 1990;76:189-197.
61. Connor RI, Rigby WF. 1 alpha,25-dihydroxyvitamin D3 inhibits productive infection of human monocytes by HIV-1. Biochem Biophys Res Commun. 1991;176:852-859.
62. Schuitemaker H, Kootstra NA, Koppelman MH, et al. Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages. J Clin Invest. 1992;89:1154-1160.
63. Pauza CD, Kornbluth R, Emau P, Richman DD, Deftos LJ. Vitamin D3 compounds regulate human immunodeficiency virus type 1 replication in U937 monoblastoid cells and in monocyte-derived macrophages. J Leukoc Biol. 1993;53:157-164.
64. Locardi C, Petrini C, Boccoli G, et al. Increased human immunodeficiency virus (HIV) expression in chronically infected U937 cells upon in vitro differentiation by hydroxyvitamin D3: roles of interferon and tumor necrosis factor in regulation of HIV production. J Virol. 1990;64:5874-5882.
65. Kitano K, Baldwin GC, Raines MA, Golde DW. Differentiating agents facilitate infection of myeloid leukemia cell lines by monocytotropic HIV-1 strains. Blood. 1990;76:1980-1988.
66. Skolnik PR, Jahn B, Wang MZ, Rota TR, Hirsch MS, Krane SM. Enhancement of human immunodeficiency virus 1 replication in monocytes by 1,25- dihydroxycholecalciferol. Proc Natl Acad Sci U S A. 1991;88:6632-6636.
67. Kizaki M, Ikeda Y, Simon KJ, Nanjo M, Koeffler HP. Effect of 1,25-dihydroxyvitamin D3 and its analogs on human immunodeficiency virus infection in monocytes/macrophages. Leukemia. 1993;7:1525-1530.
68. Goletti D, Kinter AL, Biswas P, Bende SM, Poli G, Fauci AS. Effect of cellular differentiation on cytokine-induced expression of human immunodeficiency virus in chronically infected promonocytic cells: dissociation of cellular differentiation and viral expression. J Virol. 1995;69:2540-2546.
69. Boulerice F, Geleziunas R, Bour S, et al. Differential susceptibilities of U-937 cell clones to infection by human immunodeficiency virus type 1. J Virol. 1992;66:1183-1187.
70. Biswas P, Mengozzi M, Mantelli B, et al. 1,25-Dihydroxyvitamin D3 upregulates functional CXCR4 human immunodeficiency virus type 1 coreceptors in U937 minus clones: NF-kappaB-independent enhancement of viral replication. J Virol. 1998;72:8380-8383.
71. Gray JD, Bottomley W, Layton AM, Cotterill JA, Monteiro E. The use of calcipotriol in HIV-related psoriasis. Clin Exp Dermatol. 1992;17:342-343.
72. Barber Y, Rubio C, Fernandez E, Rubio M, Fibla J. Host genetic background at CCR5 chemokine receptor and vitamin D receptor loci and human immunodeficiency virus (HIV) type 1 disease progression among HIV-seropositive injection drug users. J Infect Dis. 2001;184:1279-1288.
73. Morrison NA, Qi JC, Tokita A, et al. Prediction of bone density from vitamin D receptor alleles. Nature. 1994;367:284-287.
74. Nieto G, Barber Y, Rubio MC, Rubio M, Fibla J. Association between AIDS disease progression rates and the Fok-I polymorphism of the VDR gene in a cohort of HIV-1 seropositive patients. J Steroid Biochem Mol Biol. 2004;90:199-207.
75. Hill AV. The immunogenetics of human infectious diseases. Annu Rev Immunol. 1998;16:593-617.
76. Hayes VM. The genetics of susceptibility to HIV/AIDS: how does Africa differ? Presented at: AIDS Vaccine 2003. September 18, 2003; New York.