PI3-K/Akt and ERK pathways activated by VEGF play opposite roles in MPP+-induced neuronal apoptosis

Neurochemistry International

Volumn 59, Issue 6, 2011, Pages 945-953

  Cui, Wei ^a   Li, Wenming ^a,b   Han, Renwen ^a   Mak, Shinghung ^a   Zhang, Huan ^a   Hu, Shengquan ^a   Rong, Jianhui ^c   Han, Yifan ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c THE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Akt; Apoptosis; ERK; Neuroprotection; Parkinson's disease; VEGF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; VASCULOTROPIN; VATALANIB;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; GRANULE CELL; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; DRUG ADMINISTRATION SCHEDULE; MAP KINASE SIGNALING SYSTEM; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; PHOSPHATIDYLINOSITOL 3-KINASES; PRIMARY CELL CULTURE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80255135581     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.07.005     Document Type: Article

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