Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR

Brain Research

Volumn 1401, Issue , 2011, Pages 10-17

  Cui, Wei ^a   Cui, Guo Zhen ^b   Li, Wenming ^a   Zhang, Zaijun ^b   Hu, Shengquan ^a   Mak, Shinghung ^a   Zhang, Huan ^a   Carlier, Paul R ^c   Choi, Chung Lit ^a   Wong, Yi Tao ^b   Lee, Simon Ming Yuen ^b   Han, Yifan ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b University of Macau   (Macao)

^c VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

7nAChR; Bis(12) hupyridone; Differentiation; Huperzine A; Neural stem cell; Neurodegenerative disorder

Indexed keywords

BIS(12) HUPYRIDONE; BUNGAROTOXIN RECEPTOR; CHOLINESTERASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HUPERZINE A; MITOGEN ACTIVATED PROTEIN KINASE; PYRIDONE DERIVATIVE; TRANSCRIPTION FACTOR ELK 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HIPPOCAMPUS; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEURAL STEM CELL; NEURITE; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYLCHOLINESTERASE; ALKALOIDS; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; DIMERIZATION; NEURAL STEM CELLS; PC12 CELLS; QUINOLONES; RATS; RECEPTORS, NICOTINIC; SESQUITERPENES;

MUS; RATTUS;

EID: 79959760304     PISSN: 00068993     EISSN: 00068993     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.05.042     Document Type: Article

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