Interleukin-1β-stimulated invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific integrin receptors and by collagenase inhibitors

Arthritis and Rheumatism

Volumn 40, Issue 7, 1997, Pages 1298-1307

  Wang, Allan Z ^a   Wang, Jane C ^a   Fisher, Gregory W ^b   Diamond, Herbert S ^a  

^a WESTERN PENNSYLVANIA HOSPITAL   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; COLLAGENASE INHIBITOR; INTEGRIN; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; ALPHA4 INTEGRIN; ALPHA5 INTEGRIN; ANTIBODY; BETA1 INTEGRIN; CD51 ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 8; LEUKOCYTE ANTIGEN;

ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE MATRIX; CATTLE; CELL INVASION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; TISSUE SLICE; CELL CULTURE; DRUG ANTAGONISM; IMMUNOLOGY; IN VITRO STUDY; OSTEOARTHRITIS; PATHOLOGY; PHYSIOLOGY; SYNOVIUM;

ANTIBODIES; ANTIGENS, CD; ANTIGENS, CD29; ARTHRITIS, RHEUMATOID; CARTILAGE, ARTICULAR; CELLS, CULTURED; COLLAGENASES; FIBROBLASTS; HUMANS; INTEGRIN ALPHA4; INTEGRIN ALPHA5; INTEGRIN ALPHAV; INTEGRINS; INTERLEUKIN-1; INTERLEUKIN-8; OSTEOARTHRITIS; RECEPTORS, INTERLEUKIN-1; SYNOVIAL MEMBRANE;

EID: 0030612494     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780400715     Document Type: Article

References (46)

1. Shiozawa S, Tokushisa T: Contribution of synovial mesenchymal cells to the pathogenesis of rheumatoid arthritis. Semin Arthritis Rheum 21:267-273, 1992
2. Shiozawa S, Yoshihara R, Kuroki Y, Fujita T, Shiozawa K, Imura S: Pathogenic importance of fibronectin in the superficial region of articular cartilage as a local factor for the induction of pannus extension on rheumatoid articular cartilage. Ann Rheum Dis 51:869-873, 1992
3. McCarthy JB, Hagen ST, Furcht LT: Human fibronectin contains distinct adhesion- and motility-promoting domains for metastatic melanoma cells. J Cell Biol 102:179-188, 1986
4. Wang AZ, Chen JM, Fisher GW, Wang JC, Diamond HS: Improved in vitro models for assay of rheumatoid synoviocyte chemotaxis. Clin Exp Rheumatol 12:293-299, 1994
5. Frye C, Yocum D, Benjamin J, Hendrix M: Transformed pheno-type of the rheumatoid synoviocyte shows invasion of basement membrane matrix and enhanced migration (abstract). Arthritis Rheum 35 (suppl 9):S139, 1992
6. Rinaldi N, Barth T, Henne C, Mechtersheimer G, Möller P: Synoviocytes in chronic synovitis in situ and cytokine stimulated synovial cells in vitro neo-express alpha 1, alpha 3 and alpha 5 chains of beta 1 integrins. Virchows Arch 425:171-180, 1994
7. Ishikawa H, Hirata S, Nishibayashi Y, Imura S, Kubo H, Ohno O: The role of adhesion molecules in synovial pannus formation in rheumatoid arthritis. Clin Orthop 300:297-303, 1994
8. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS Medsger TA Jr, Mitchell DM, Neustadt DH, Pinals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315-324, 1988
9. Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, Christy W, Cooke TD, Greenwald R, Hochberg M, Howell D, Kaplan D, Koopman W, Longley S III, Mankin H, McShane DJ, Medsger T Jr, Meenan R, Mikkelsen W, Moskowitz R, Murphy W, Rothschild B, Segal M, Sokoloff L, Wolfe F: Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 29:1039-1049, 1986
10. Comper WD: Cartilage - Molecular Aspects. Boca Raton, FL, CRC Press, 1991
11. Häuselmann HJ, Flechtenmacher J, Michal L, Thonar EJ-MA, Shinmei M, Kuettner KE, Aydelotte MB: The superficial layer of human articular cartilage is more susceptible to interleukin-1-induced damage than the deeper layers. Arthritis Rheum 39:478-488, 1996
12. Arend WP, Joslin FG, Massoni RJ: Characteristics of chondrocyte responses to a human interleukin 1-like factor. Clin Immunol Immnopathol 36:358-370, 1985
13. Hembry RM, Bagga M, Reynolds JJ, Hamblen DL: Immunolocalisation studies on six matrix metalloproteinase and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis. Ann Rheum Dis 54:25-32, 1995
14. Goldring MB, Birkhead J, Sandell U, Kimura T, Krane SM: Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest 82:2026-2037, 1988
15. Smith RJ, Chin JE, Sam LM, Justen JM: Biologic effects of an interleukin-1 receptor antagonist protein on interleukin-1-stimulated cartilage erosion and chondrocyte responsiveness. Arthritis Rheum 34:78-83, 1991
16. Tetlow LC, Lees M, Ogata Y, Nagase H, Woolley DE: Differential expression of gelatinase B (MMP-9) and stromelysin-1 (MMP-3) by rheumatoid synovial cells in vitro and in vivo. Rheumatol Int 13:53-59, 1993
17. Ishikawa H, Ohno O, Saura R, Matsubara T, Kuroda T, Hirohata K: Cytokine enhancement of monocyte/synovial cell attachment to the surface of cartilage: a possible trigger of pannus formation in arthritis. Rheumatol Int 11:31-36, 1991
18. Tuan R, Frye CA, Yocum DE, Seftor EA, Moore TL, Hendrix MJC: An in vitro model for studying mechanisms underlying synovial fibroblast mediated cartilage destruction in rheumatoid arthritis (abstract). Arthritis Rheum 37 (suppl 9):S311, 1994
19. Frye CA, Tuan R, Yocum DE, Hendrix MJC: An in vitro model for studying mechanisms underlying cartilage destruction associated with rheumatoid arthritis (abstract). Arthritis Rheum 36 (suppl 9):S174, 1993
20. Recklies AD, Golds EE: Induction of synthesis and release of interleukin-8 from human articular chondrocytes and cartilage explants. Arthritis Rheum 35:1510-1519, 1992
21. Miyasaka N: Cytokines and chemical mediators in rheumatoid arthritis. Nippon Rinsho 50:463-469, 1992
22. Endo H, Akahoshi T, Takagishi K, Kashiwazaki S, Matsushima K: Elevation of interleukin-8 (IL-8) levels in joint fluids of patients with rheumatoid arthritis and the induction by IL-8 of leukocyte infiltration and synovitis in rabbit joints. Lymphokine Cytokine Res 10:245-252, 1991
23. Koch AE, Kunkel SL, Burrows JC, Evanoff HL, Haines GK, Pope RM, Strieter RM: Synovial tissue macrophage as a source of the chemotactic cytokine IL-8. J Immunol 147:2187-2195, 1991
24. Ishikawa H, Hirata S, Nishibayashi Y, Kubo H, Osamu O, Imura S: Cytokine enhancement of adhesion molecule expression on cultured synovial cells at the surface of cartilage: a possible trigger of pannus formation in arthritis (abstract). Arthritis Rheum 36 (suppl 9):S265, 1993
25. Taylor DJ: Interleukin-4 (IL-4) induces down-modulation and shedding of the p55 tumour necrosis factor receptor and inhibits TNF alpha's effect on rheumatoid synovial fibroblasts. Rheumatol Int 14:21-25, 1994
26. Henderson B, Pettipher ER: Arthritogenic actions of recombinant IL-1 and tumor necrosis factor α in the rabbit: evidence for synergistic interactions between cytokines in vivo. Clin Exp Immunol 75:306-310, 1989
27. Chu CQ, Field M, Feldmann M, Maini RN: Localization of tumor necrosis factor α in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 34:1125-1132, 1991
28. Mohamed-Ali H: Influence of synovial cells on cartilage in vitro: induction of breakdown and inhibition of synthesis. Virchows Arch B Cell Pathol 62:227-236, 1992
29. Farahat MN, Yanni G, Poston R, Panayi GS: Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 52:870-875, 1993
30. Kahle P, Saal JG, Schaudt K, Zacher J, Fritz P, Pawelec G: Determination of cytokines in synovial fluids: correlation with diagnosis and histomorphological characteristics of synovial tissue. Ann Rheum Dis 51:731-734, 1992
31. Arend WP, Welgus HG, Thompson RC, Eisenberg SP: Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist. J Clin Invest 85:1694-1697, 1990
32. Firestein GS, Boyle DL, Yu C, Paine MM, Whisenand TD, Zvaifler NJ, Arend WP: Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis. Arthritis Rheum 37:644-652, 1994
33. Deleuran BW, Chu CQ, Field M, Brennan FM, Katsikis P, Feldmann M, Maini RN: Localization of interleukin-1α, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis. Br J Rheumatol 31:801-809, 1992
34. Haas TA, Plow EF: Integrin-ligand interactions: a year in review. Curr Opin Cell Biol 6:656-662, 1994
35. Yamada KM, Aota S, Akiyama SK, La Flamme SE: Mechanisms of fibronectin and integrin function during cell adhesion and migration. Cold Spring Harb Symp Quant Biol 152:203-212, 1992
36. Nikkari L, Aho H, Yli-Jama T, Larjava H, Jalkanen M, Heino J: Expression of integrin family of cell adhesion receptors in rheumatoid synovium: alpha 6 integrin subunit in normal and hyperplastic synovial lining cell layer. Am J Pathol 142:1019-1027, 1993
37. Schneider M, Voss B, Rauterberg J, Menke M, Pauly TH, Miehlke RK, Friemann J, Gerlach U: Basement membrane proteins in synovial membrane: distribution in rheumatoid arthritis and synthesis by fibroblast-like cells. Clin Rheumatol 13:90-97, 1994
38. Demaziere A, Athanasou NA: Adhesion receptors of intimal and subintimal cells of the normal synovial membrane. J Pathol 168:209-215, 1992
39. Hocking DC, Smith RK, McKeown-Longo PJ: A novel role for the integrin-binding III-10 module in fibronectin matrix assembly. J Cell Biol 133:431-444, 1996
40. Makarem R, Newham P, Askari JA, Green LJ, Clements J, Edwards M, Humphries MJ, Mould AP: Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1. J Biol Chem 269:4005-4011, 1994
41. Makarem R, Humphries MJ: LDV: a novel cell adhesion motif recognized by the integrin alpha 4 beta 1. Biochem Soc Trans 19:380S, 1991
42. Huhtala P, Humphries MJ, McCarthy JB, Tremble PM, Werb Z, Damsky CH: Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J Cell Biol 129:867-879, 1995
43. Trabandt A, Aicher W, Gay R, Sukhatme VP, Nilson-Hamilton M, Hamilton RT, Mcghee JR, Fassbender HG, Gay S: Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts. Matrix 10: 349-361, 1990
44. Hutchinson NI, Lark MW, MacNaul KL, Harper C, Hoerrner LA, McDonnell J, Donatelli S, Moore V, Bayne EK: In vivo expression of stromelysin in synovium and cartilage of rabbits injected intraarticularly with interleukin-1β. Arthritis Rheum 35:1227-1233, 1992
45. Case JP, Lafyatis R, Remmers EF, Kumkumian GK, Wilder RL: Transin/stromelysin expression in rheumatoid synovium: a transformation-associated metalloproteinase secreted by phenotypically invasive synoviocytes. Am J Pathol 135:1055-1064, 1989
46. 2 levels of human synovial cells. Arthritis Rheum 30:562-566, 1987