Increased expression of integrins on fibroblast-like synoviocytes from rheumatoid arthritis in vitro correlates with enhanced binding to extracellular matrix proteins

Annals of the Rheumatic Diseases

Volumn 56, Issue 1, 1997, Pages 45-51

  Rinaldi, N ^a,b   Schwarz Eywill, M ^b,d   Weis, D ^c   Leppelmann Jansen, P ^a,b   Lukoschek, M ^b   Keilholz, U ^a,b   Barth, T F E ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b Department of Internal Medicine V ^*  (Germany)

^c Institute of Pathology

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; MATRIX PROTEIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

EID: 0031035590     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.56.1.45     Document Type: Article

References (35)

1. Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11-25.
2. Yokosaki Y, Palmer EL, Prieto AL, Crossin KL, Bourdon MA, Pytela R, et al. The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin. J Biol Chem 1994; 269:26691-6.
3. Rinaldi N, Barth T, Henne C, Mechtersheimer G, Möller P. Synoviocytes in chronic synovitis in situ and cytokine stimulated synovial cells in vitro neo-express α1, α3 and α5 chains of β1 integrins. Virchows Arch 1994;425:171-80.
4. Nikkari L, Aho A, Yli-Jama T, Larjava H, Jalkanen M, Heino J. Expression of integrin family of cell adhesion receptors in rheumatoid synovium. Alpha 6 integrin subunit in normal and hyperplastic synovial lining cell layer. Am J Pathol 1993;142:1019-27.
5. El-Gabalawy H, Wilkins J. β1 (CD29) integrin expression in rheumatoid synovial membranes: an immunohistologic study of distribution patterns. J Rheumatol 1993; 20:231-7.
6. Albelda SM. Role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab Invest 1993;68:4-17.
7. Levesque JP, Hatzfeld A, Hatzfeld J. Mitogenic properties of extracellular matrix proteins. Immunol Today 1991; 12:258-62.
8. Juliano RL, Haskill S. Signal transduction from the extracellular matrix. J Cell Biol 1993;111:721-9.
9. Straus AH, Carter WG, Wayner EA, Hakomori S. Mechanisms of fibronectin-mediated cell migration: dependence or independence of cell migration susceptibility on RGDS-directed receptor (integrin). Exp Cell Res 1989;183:126-39.
10. Hauzenberger D, Sundqvist KG. Functional specialization of fibronectin-binding β1- integrins in T-lymphocyte migration. J Immunol 1994;153:960-71.
11. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
12. Abrahamsen TG, Froland SS, Natvig JB, Pahle J. Elution and characterization of lymphocytes from rheumatoid inflammatory tissue. Scand J Immunol 1975;4:822-30.
13. Landegren U. Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens. J Immunol Methods 1984;67:379-88.
14. Carter WG, Wayner EA, Bouchard TS, Kaur P. The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol 1990;110:1387-404.
15. Ruan CG, Xi XD, Du XP, Wan HY, Wu X, Li PX, Gu JM. Studies on monoclonal antibodies against human platelets - a monoclonal antibody to human platelet glycoprotein I-SZ-2. Sci Sin B 1987;30:404-12.
16. Wayner EA, Carter WG. Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits. J Cell Biol 1987;105:1873-4.
17. Wayner EA, Carter WG, Piotrowicz RS, Kunicki TJ. The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa. J Cell Biol 1988;107:1881-91.
18. May MJ, Entwistle G, Humphries MJ, Ager A. VCAM-1 is a CS1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium. J Cell Sci 1993;106:109-19.
19. Weinel RJ, Rosendahl A, Neumann K, Chaloupka B, Erb D, Rothmund M, et al. Expression and function of VLA-alpha 2, -alpha 3, -alpha 5 and -alpha 6-integrin receptors in pancreatic carcinoma. Int J Cancer 1992;52:827-33.
20. Shaw LM, Messier JM, Mercurio AM. The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin. J Cell Biol 1990;110:2167-74.
21. Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, et al. CD antigens. Blood 1994;83:879-80.
22. Wynne-Roberts CR, Castor CW. Ultrastructural comparison of rheumatoid and non rheumatoid synovial fibroblasts grown in tissue culture. Arthritis Rheum 1972;15:65-83.
23. Castor CW, Ragsdale CG, Cabrai AR, Smith EM, Aaron BP. Metabolic and catabolic responses of human articular cells to growth factors. J Rheumatol 1987;14:67-9.
24. Cerola E, Pulkki K, Pelliniemi LJ, Granfors K, Vuorio E, Troivanen A. Arthritis-associated changes in flow cytometric characteristics of cultural synovial fibroblasts. Arthritis Rheum 1988;31:339-47.
25. Hernvann A, Cynober L, Aussel C, Ekindjian OG. Rheumatoid arthritis modifies basal and insulin-mediated glucose uptake by human synoviocytes. Cell Mol Biol 1991;37:541-7.
26. Goddard DH, Grossman SL, Williams WV, Weiner DB, Gross JL, Eidsvoog K, et al. Regulation of synovial cell growth. Co-expression of transforming growth factor-β and basic fibroblast growth factor by cultured synovial cells. Arthritis Rheum 1992;35:1296-303.
27. McCroskery PA, Arai S, Amento EP, Krane SM. Stimulation of procollagenase synthesis in human rheumatoid synovial fibroblasts by mononuclear cell factor/interleukin-1. FEBS Lett 1985;191:7-12.
28. Goto M, Okamoto M, Sasano M, Yanagisawa S, Miyamoto T, Nishioka K, et al. Adherent synovial cells from nonrheumatoid arthritis do not release interleukin 1 beta and prostaglandin E2 spontaneously in long term culture. J Rheumatol 1990;17:1299-302.
29. Gailit J, Ruoslahti E. Regulation of the fibronectin receptor affinity by divalent cations. J Biol Chem 1988;263:12927-32.
30. Sriamarao P, Mendler M, Bourdon MA. Endothelial cell attachment and spreading on human tenascin is mediated by α2β1 and αvβ3 integrins. J Cell Sci 1993;105:1001-12.
31. Yokosaki Y, Palmer EL, Prieto AL, Crossin KL, Bourdon MA, Pytela R, et al. The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin. J Biol Chem 1994; 269:26691-6.
32. Cutolo M, Picasso M, Ponassi M, Zhen Sun M, Balza E. Tenascin and fibronectin distribution in human normal and pathological synovium. J Rheumatol 1992;19:1439-47.
33. Suzuki H. Fibronectin in the synovium and synovial fluid in rheumatoid arthritis and in osteoarthritis. Nippon-Seikeigeka-Gakkai-Zasshi 1994;68:172-83.
34. Tremble P, Chiquet-Ehrismann R, Werb Z. The extracellular matrix ligands fibronectin and tenascin collaborate in regulating collagenase gene expression in fibroblasts. Mol Biol Cell 1994;5:439-53.
35. Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol 1989;109:877-89.