Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: Synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies

Arthritis Research and Therapy

Volumn 11, Issue 4, 2009, Pages

  Moran, Ellen M ^a   Mullan, Ronan ^a   McCormick, Jennifer ^a   Connolly, Mary ^a   Sullivan, Owen ^a   FitzGerald, Oliver ^a   Bresnihan, Barry ^a   Veale, Douglas J ^a   Fearon, Ursula ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; COLLAGENASE 3; COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C2; GELATINASE A; GELATINASE B; INTERLEUKIN 17; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; ONCOSTATIN M; PROTEOGLYCAN; SERUM AMYLOID A; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; ANTIRHEUMATIC AGENT;

ARTICLE; BIOLOGICAL THERAPY; BONE MATRIX; BONE TURNOVER; CARTILAGE CELL; CARTILAGE DEGENERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; OSTEOARTHRITIS; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIUM; TREATMENT DURATION; UPREGULATION; ZYMOGRAPHY; CARTILAGE; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; EXTRACELLULAR MATRIX; IMMUNOHISTOCHEMISTRY; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY;

ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; BIOLOGICAL THERAPY; CARTILAGE; CELLS, CULTURED; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-17; MATRIX METALLOPROTEINASES; ONCOSTATIN M; ORGAN CULTURE TECHNIQUES; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 68949158362     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2772     Document Type: Article

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