메뉴 건너뛰기




Volumn 71, Issue 21, 2011, Pages 6561-6566

PAR-1 and thrombin: The ties that bind the microenvironment to melanoma metastasis

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CONNEXIN 43; FIBRIN; INTERSTITIAL COLLAGENASE; MASPIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 1 INHIBITOR; THROMBIN; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 80155171682     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-1432     Document Type: Review
Times cited : (80)

References (37)
  • 1
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • DOI 10.1038/nrc1098
    • Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil'hypothesis revisited. Nat Rev Cancer 2003;3:453-8. (Pubitemid 37328849)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 453-458
    • Fidler, I.J.1
  • 2
    • 55749112156 scopus 로고    scopus 로고
    • Melanoma and the tumor microenvironment
    • Villanueva J, Herlyn M. Melanoma and the tumor microenvironment. Curr Oncol Rep 2008;10:439-46.
    • (2008) Curr Oncol Rep , vol.10 , pp. 439-446
    • Villanueva, J.1    Herlyn, M.2
  • 4
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000;407:258-64.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 5
    • 79960883524 scopus 로고    scopus 로고
    • The emerging role of the thrombin receptor (PAR-1) in melanoma metastasis-a possible therapeutic target
    • Villares GJ, Zigler M, Bar-Eli M. The emerging role of the thrombin receptor (PAR-1) in melanoma metastasis-a possible therapeutic target. Oncotarget 2011;2:8-17.
    • (2011) Oncotarget , vol.2 , pp. 8-17
    • Villares, G.J.1    Zigler, M.2    Bar-Eli, M.3
  • 6
    • 49649107043 scopus 로고    scopus 로고
    • Thrombin up-regulates cathepsin D which enhances angiogenesis, growth, and metastasis
    • Hu L, Roth JM, Brooks P, Luty J, Karpatkin S. Thrombin up-regulates cathepsin D which enhances angiogenesis, growth, and metastasis. Cancer Res 2008;68:4666-73.
    • (2008) Cancer Res , vol.68 , pp. 4666-4673
    • Hu, L.1    Roth, J.M.2    Brooks, P.3    Luty, J.4    Karpatkin, S.5
  • 8
    • 33750616197 scopus 로고    scopus 로고
    • Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated dormant tumor phenotype
    • DOI 10.1016/j.ccr.2006.10.002, PII S1535610806002868
    • Nierodzik ML, Karpatkin S. Thrombin induces tumor growth, metastasis, and angiogenesis: evidence for a thrombin-regulated dormant tumor phenotype. Cancer Cell 2006;10:355-62. (Pubitemid 44693468)
    • (2006) Cancer Cell , vol.10 , Issue.5 , pp. 355-362
    • Nierodzik, M.L.1    Karpatkin, S.2
  • 9
    • 0141819106 scopus 로고    scopus 로고
    • Tissue factor, thrombin, and cancer
    • Rickles FR, Patierno S, Fernandez PM. Tissue factor, thrombin, and cancer. Chest 2003;124[Suppl]:58S-68S. (Pubitemid 37128437)
    • (2003) Chest , vol.124 , Issue.3 SUPPL.
    • Rickles, F.R.1    Patierno, S.2    Fernandez, P.M.3
  • 11
    • 55349098455 scopus 로고    scopus 로고
    • Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA
    • Villares GJ, Zigler M, Wang H, Melnikova VO, Wu H, Friedman R, et al. Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA. Cancer Res 2008;68:9078-86.
    • (2008) Cancer Res , vol.68 , pp. 9078-9086
    • Villares, G.J.1    Zigler, M.2    Wang, H.3    Melnikova, V.O.4    Wu, H.5    Friedman, R.6
  • 12
    • 70350398248 scopus 로고    scopus 로고
    • Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis
    • Melnikova VO, Balasubramanian K, Villares GJ, Dobroff AS, Zigler M, Wang H, et al. Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis. J Biol Chem 2009;284:28845-55.
    • (2009) J Biol Chem , vol.284 , pp. 28845-28855
    • Melnikova, V.O.1    Balasubramanian, K.2    Villares, G.J.3    Dobroff, A.S.4    Zigler, M.5    Wang, H.6
  • 13
    • 69249096952 scopus 로고    scopus 로고
    • Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43
    • Villares GJ, Dobroff AS, Wang H, Zigler M, Melnikova VO, Huang L, et al. Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43. Cancer Res 2009;69:6730-7.
    • (2009) Cancer Res , vol.69 , pp. 6730-6737
    • Villares, G.J.1    Dobroff, A.S.2    Wang, H.3    Zigler, M.4    Melnikova, V.O.5    Huang, L.6
  • 14
    • 79551678748 scopus 로고    scopus 로고
    • Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype
    • Villares GJ, Zigler M, Dobroff AS, Wang H, Song R, Melnikova VO, et al. Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype. Proc Natl Acad Sci U S A 2011;108:626-31.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 626-631
    • Villares, G.J.1    Zigler, M.2    Dobroff, A.S.3    Wang, H.4    Song, R.5    Melnikova, V.O.6
  • 15
    • 3543121913 scopus 로고    scopus 로고
    • Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis
    • Shi X, Gangadharan B, Brass LF, Ruf W, Mueller BM. Proteaseactivated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Mol Cancer Res 2004;2:395-402. (Pubitemid 39031073)
    • (2004) Molecular Cancer Research , vol.2 , Issue.7 , pp. 395-402
    • Shi, X.1    Gangadharan, B.2    Brass, L.F.3    Ruf, W.4    Mueller, B.M.5
  • 16
    • 34147206365 scopus 로고    scopus 로고
    • Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression
    • DOI 10.1158/1541-7786.MCR-06-0261
    • Salah Z, Maoz M, Pokroy E, Lotem M, Bar-Shavit R, Uziely B. Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression. Mol Cancer Res 2007;5:229-40. (Pubitemid 46577967)
    • (2007) Molecular Cancer Research , vol.5 , Issue.3 , pp. 229-240
    • Salah, Z.1    Maoz, M.2    Pokroy, E.3    Lotem, M.4    Bar-Shavit, R.5    Uziely, B.6
  • 17
    • 71349087406 scopus 로고    scopus 로고
    • A matrix metalloproteinase- 1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis
    • Blackburn JS, Liu I, Coon CI, Brinckerhoff CE. A matrix metalloproteinase- 1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis. Oncogene 2009;28:4237-48.
    • (2009) Oncogene , vol.28 , pp. 4237-4248
    • Blackburn, J.S.1    Liu, I.2    Coon, C.I.3    Brinckerhoff, C.E.4
  • 18
    • 34247388037 scopus 로고    scopus 로고
    • Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer
    • DOI 10.1242/jcs.03409
    • Arora P, Ricks TK, Trejo J. Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer. J Cell Sci 2007;120: 921-8. (Pubitemid 46638507)
    • (2007) Journal of Cell Science , vol.120 , Issue.6 , pp. 921-928
    • Arora, P.1    Ricks, T.K.2    Trejo, J.3
  • 19
    • 1342325343 scopus 로고    scopus 로고
    • Persistent Signaling by Dysregulated Thrombin Receptor Trafficking Promotes Breast Carcinoma Cell Invasion
    • DOI 10.1128/MCB.24.5.1990-1999.2004
    • Booden MA, Eckert LB, Der CJ, Trejo J. Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion. Mol Cell Biol 2004;24:1990-9. (Pubitemid 38248939)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.5 , pp. 1990-1999
    • Booden, M.A.1    Eckert, L.B.2    Der, C.J.3    Trejo, J.4
  • 21
    • 68049143326 scopus 로고    scopus 로고
    • Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
    • Yang E, Boire A, Agarwal A, Nguyen N, O'Callaghan K, Tu P, et al. Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res 2009;69:6223-31.
    • (2009) Cancer Res , vol.69 , pp. 6223-6231
    • Yang, E.1    Boire, A.2    Agarwal, A.3    Nguyen, N.4    O'Callaghan, K.5    Tu, P.6
  • 22
    • 0037406817 scopus 로고    scopus 로고
    • Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells
    • Darmoul D, Gratio V, Devaud H, Lehy T, Laburthe M. Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells. Am J Pathol 2003;162:1503-13. (Pubitemid 36512832)
    • (2003) American Journal of Pathology , vol.162 , Issue.5 , pp. 1503-1513
    • Darmoul, D.1    Gratio, V.2    Devaud, H.3    Lehy, T.4    Laburthe, M.5
  • 24
    • 2942530298 scopus 로고    scopus 로고
    • Amplification of MMP-2 and MMP-9 production by prostate cancer cell lines via activation of protease-activated receptors
    • DOI 10.1002/pros.20047
    • Wilson SR, Gallagher S, Warpeha K, Hawthorne SJ. Amplification of MMP-2 and MMP-9 production by prostate cancer cell lines via activation of protease-activated receptors. Prostate 2004;60:168-74. (Pubitemid 38758582)
    • (2004) Prostate , vol.60 , Issue.2 , pp. 168-174
    • Wilson, S.R.1    Gallagher, S.2    Warpeha, K.3    Hawthorne, S.J.4
  • 25
    • 0034969753 scopus 로고    scopus 로고
    • Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues
    • D'Andrea MR, Derian CK, Santulli RJ, Andrade-Gordon P. Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues. Am J Pathol 2001;158:2031-41. (Pubitemid 32545189)
    • (2001) American Journal of Pathology , vol.158 , Issue.6 , pp. 2031-2041
    • D'Andrea, M.R.1    Derian, C.K.2    Santulli, R.J.3    Andrade-Gordon, P.4
  • 26
    • 33646003861 scopus 로고    scopus 로고
    • Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells
    • Tarzami ST, Wang G, Li W, Green L, Singh JP. Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells. J Thromb Haemost 2006;4:656-63.
    • (2006) J Thromb Haemost , vol.4 , pp. 656-663
    • Tarzami, S.T.1    Wang, G.2    Li, W.3    Green, L.4    Singh, J.P.5
  • 27
    • 79953092222 scopus 로고    scopus 로고
    • Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection
    • Sen P, Gopalakrishnan R, Kothari H, Keshava S, Clark CA, Esmon CT, et al. Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection. Blood 2011;117:3199-208.
    • (2011) Blood , vol.117 , pp. 3199-3208
    • Sen, P.1    Gopalakrishnan, R.2    Kothari, H.3    Keshava, S.4    Clark, C.A.5    Esmon, C.T.6
  • 29
    • 3142592165 scopus 로고    scopus 로고
    • Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis
    • DOI 10.1182/blood-2004-02-0434
    • Camerer E, Qazi AA, Duong DN, Cornelissen I, Advincula R, Coughlin SR. Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis. Blood 2004;104:397-401. (Pubitemid 38900020)
    • (2004) Blood , vol.104 , Issue.2 , pp. 397-401
    • Camerer, E.1    Qazi, A.A.2    Duong, D.N.3    Cornelissen, I.4    Advincula, R.5    Coughlin, S.R.6
  • 30
    • 0023946733 scopus 로고
    • Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo
    • Karpatkin S, Pearlstein E, Ambrogio C, Coller BS. Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. J Clin Invest 1988;81:1012-9.
    • (1988) J Clin Invest , vol.81 , pp. 1012-1019
    • Karpatkin, S.1    Pearlstein, E.2    Ambrogio, C.3    Coller, B.S.4
  • 31
    • 64249129547 scopus 로고    scopus 로고
    • Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site
    • Trivedi V, Boire A, Tchernychev B, Kaneider NC, Leger AJ, O'Callaghan K, et al. Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site. Cell 2009;137: 332-43.
    • (2009) Cell , vol.137 , pp. 332-343
    • Trivedi, V.1    Boire, A.2    Tchernychev, B.3    Kaneider, N.C.4    Leger, A.J.5    O'Callaghan, K.6
  • 32
    • 0141905920 scopus 로고    scopus 로고
    • Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1
    • DOI 10.1042/BJ20030346
    • Chalmers CJ, Balmanno K, Hadfield K, Ley R, Cook SJ. Thrombin inhibits Bim (Bcl-2-interacting mediator of cell death) expression and prevents serum-withdrawal-induced apoptosis via protease-activated receptor 1. Biochem J 2003;375:99-109. (Pubitemid 37255385)
    • (2003) Biochemical Journal , vol.375 , Issue.1 , pp. 99-109
    • Chalmers, C.J.1    Balmanno, K.2    Hadfield, K.3    Ley, R.4    Cook, S.J.5
  • 34
    • 77949876317 scopus 로고    scopus 로고
    • Thrombin receptor antagonism-the potential of antiplatelet medication SCH 530348
    • Macaulay TE, Allen C, Ziada KM. Thrombin receptor antagonism-the potential of antiplatelet medication SCH 530348. Expert Opin Pharmacother 2010;11:1015-22.
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1015-1022
    • Macaulay, T.E.1    Allen, C.2    Ziada, K.M.3
  • 35
    • 74849103625 scopus 로고    scopus 로고
    • Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype
    • Silini A, Ghilardi C, Ardinghi C, Bernasconi S, Oliva P, Carraro F, et al. Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype. Clin Exp Metastasis 2010;27:43-53.
    • (2010) Clin Exp Metastasis , vol.27 , pp. 43-53
    • Silini, A.1    Ghilardi, C.2    Ardinghi, C.3    Bernasconi, S.4    Oliva, P.5    Carraro, F.6
  • 37
    • 72249120877 scopus 로고    scopus 로고
    • Thrombin's central role in angiogenesis and pathophysiological processes
    • Tsopanoglou NE, Maragoudakis ME. Thrombin's central role in angiogenesis and pathophysiological processes. Eur Cytokine Netw 2009;20:171-9.
    • (2009) Eur Cytokine Netw , vol.20 , pp. 171-179
    • Tsopanoglou, N.E.1    Maragoudakis, M.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.