Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype

Clinical and Experimental Metastasis

Volumn 27, Issue 1, 2010, Pages 43-53

  Silini, Antonietta ^a   Ghilardi, Carmen ^a   Ardinghi, Camilla ^b   Bernasconi, Sergio ^a   Oliva, Paolo ^a   Carraro, Fabio ^b   Naldini, Antonella ^b   Bani, Maria Rosa ^a   Giavazzi, Raffaella ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

Invasion; Malignant melanoma; Metastasis; Migration; Protease activated receptor 1 (PAR 1)

Indexed keywords

[(METHYL) 7H PYRROLOQUINAZOLINE 1,3 DIAMINE]; ANTINEOPLASTIC AGENT; MESSENGER RNA; PROTEINASE ACTIVATED RECEPTOR 1; RECEPTOR BLOCKING AGENT; SCH 79797; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER PATIENT; CANCER TISSUE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE SILENCING; HUMAN; HUMAN CELL; LUNG CARCINOGENESIS; LUNG METASTASIS; MELANOMA; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SCID MOUSE; TUMOR PROMOTION;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; DISEASE PROGRESSION; HUMANS; MELANOMA; MICE; MICE, SCID; NEOPLASM METASTASIS; PYRROLES; QUINAZOLINES; RECEPTOR, PAR-1; SKIN NEOPLASMS;

EID: 74849103625     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-009-9301-8     Document Type: Article

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