Bacteria modulate the CD8+ T cell epitope repertoire of host Cytosol-Exposed proteins to manipulate the host immune response

PLoS Computational Biology

Volumn 7, Issue 10, 2011, Pages

  Maman, Yaakov ^a   Nir Paz, Ran ^b   Louzoun, Yoram ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; EPITOPES; IMMUNE SYSTEM; MOLECULAR BIOLOGY; PHYSIOLOGY; PROTEINS; T-CELLS; VIRUSES;

ADAPTIVE IMMUNE RESPONSE; B CELLS; BACTERIAL PROTEIN; CD4 T-CELLS; CYTOSOLS; EXPOSED TO; HOST CELLS; HOST IMMUNE RESPONSE; T-CELL EPITOPES; T-CELL RESPONSE;

BACTERIA;

BACTERIAL PROTEIN; CARRIER PROTEIN; EARLY SECRETORY ANTIGENIC TARGET 6; EPITOPE; LISTERIOLYSIN O; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING; UNCLASSIFIED DRUG; HLA ANTIGEN;

ALLELE; APOPTOSIS; ARTICLE; BACTERIAL SURVIVAL; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOSOL; ESCHERICHIA COLI; HOST PATHOGEN INTERACTION; HYDROPHOBICITY; IMMUNE EVASION; IMMUNE RESPONSE; IMMUNOMODULATION; LISTERIA MONOCYTOGENES; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOSOME; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PSEUDOMONAS AERUGINOSA; SHIGELLA FLEXNERI; TYPE III SECRETION SYSTEM; ALGORITHM; BACTERIAL PHENOMENA AND FUNCTIONS; CLASSIFICATION; GENETICS; HUMAN; IMMUNOLOGY; MUTATION; VALIDATION STUDY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA; PSEUDOMONAS AERUGINOSA;

ALGORITHMS; ALLELES; BACTERIAL PHYSIOLOGICAL PHENOMENA; CD8-POSITIVE T-LYMPHOCYTES; CYTOSOL; EPITOPES; HLA ANTIGENS; HUMANS; MUTATION;

EID: 80055078431     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002220     Document Type: Article

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