메뉴 건너뛰기




Volumn 8, Issue 1, 2011, Pages 51-67

Islet transplantation and encapsulation: An update on recent developments

Author keywords

Alginate poly l lysine; Encapsulation; Islet transplantation; Microcapsules; Pericapsular fibrotic overgrowth; Sulphated glucomannanbarium alginate

Indexed keywords

ALEMTUZUMAB; ALGINATE POLYLYSINE ALGINATE; ALGINIC ACID; AZATHIOPRINE; BARIUM DERIVATIVE; BELATACEPT; CORTICOSTEROID; CYCLOSPORIN; DACLIZUMAB; INSULIN; MANNURONIC ACID; POLYACRYLONITRILE; POLYVINYLCHLORIDE; RAPAMYCIN; RITUXIMAB; TACROLIMUS; THYMOCYTE ANTIBODY; TRANSCRIPTOME;

EID: 80055075197     PISSN: 16136071     EISSN: 16140575     Source Type: Journal    
DOI: 10.1900/RDS.2011.8.51     Document Type: Review
Times cited : (146)

References (123)
  • 1
    • 0029954214 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus
    • Tisch R, McDevitt H. Insulin-dependent diabetes mellitus. Cell 1996. 85(3):291-297.
    • (1996) Cell , vol.85 , Issue.3 , pp. 291-297
    • Tisch, R.1    McDevitt, H.2
  • 2
    • 0035814696 scopus 로고    scopus 로고
    • Islet and stem cell transplantation for treating diabetes
    • Serup P, Madsen OD, Mandrup-Poulsen T. Islet and stem cell transplantation for treating diabetes. BMJ 2001. 322(7277):29-32.
    • (2001) BMJ , vol.322 , Issue.7277 , pp. 29-32
    • Serup, P.1    Madsen, O.D.2    Mandrup-Poulsen, T.3
  • 3
    • 33751076857 scopus 로고    scopus 로고
    • Association between impaired glucose metabolism and quality of life: Results from the Australian diabetes obesity and lifestyle study
    • Tapp RJ, Dunstan DW, Phillips P, Tonkin A, Zimmet PZ, Shaw JE. Association between impaired glucose metabolism and quality of life: Results from the Australian diabetes obesity and lifestyle study. Diabetes Res Clin Pract 2006. 74(2):154-161.
    • (2006) Diabetes Res Clin Pract , vol.74 , Issue.2 , pp. 154-161
    • Tapp, R.J.1    Dunstan, D.W.2    Phillips, P.3    Tonkin, A.4    Zimmet, P.Z.5    Shaw, J.E.6
  • 4
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993. 329(14):977-986.
    • (1993) N Engl J Med , vol.329 , Issue.14 , pp. 977-986
  • 5
    • 0014093712 scopus 로고
    • Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy
    • Kelly WD, Lillehei RC, Merkel FK, Idezuki Y, Goetz FC. Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery 1967. 61(6):827-837.
    • (1967) Surgery , vol.61 , Issue.6 , pp. 827-837
    • Kelly, W.D.1    Lillehei, R.C.2    Merkel, F.K.3    Idezuki, Y.4    Goetz, F.C.5
  • 6
    • 0023526914 scopus 로고
    • Pancreas transplant protocols at the University of Minnesota: Recipient and donor selection, operative and postoperative management, and outcome
    • Sutherland DE, Moudry KC, Elick BA, Goetz FC, Najarian JS. Pancreas transplant protocols at the University of Minnesota: recipient and donor selection, operative and postoperative management, and outcome. Clin Transpl 1987: 109-126.
    • (1987) Clin Transpl , pp. 109-126
    • Sutherland, D.E.1    Moudry, K.C.2    Elick, B.A.3    Goetz, F.C.4    Najarian, J.S.5
  • 8
    • 20344403093 scopus 로고    scopus 로고
    • Immunosuppression after pancreas transplantation
    • Gruessner RW. Immunosuppression after pancreas transplantation. Transplant Proc 2005. 37:1663-1666.
    • (2005) Transplant Proc , vol.37 , pp. 1663-1666
    • Gruessner, R.W.1
  • 9
    • 0015386234 scopus 로고
    • Transplantation of intact pancreatic islets in rats
    • Ballinger WF, Lacy PE. Transplantation of intact pancreatic islets in rats. Surgery 1972. 72(2):175-186.
    • (1972) Surgery , vol.72 , Issue.2 , pp. 175-186
    • Ballinger, W.F.1    Lacy, P.E.2
  • 11
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000. 343(4):230-238.
    • (2000) N Engl J Med , vol.343 , Issue.4 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3    Korbutt, G.S.4    Toth, E.5    Warnock, G.L.6    Kneteman, N.M.7    Rajotte, R.V.8
  • 14
    • 0035149610 scopus 로고    scopus 로고
    • Prevention of diabetes for up to 13 years by autoislet transplantation after pancreatectomy for chronic pancreatitis
    • Robertson RP, Lanz KJ, Sutherland DE, Kendall DM. Prevention of diabetes for up to 13 years by autoislet transplantation after pancreatectomy for chronic pancreatitis. Diabetes 2001. 50(1):47-50.
    • (2001) Diabetes , vol.50 , Issue.1 , pp. 47-50
    • Robertson, R.P.1    Lanz, K.J.2    Sutherland, D.E.3    Kendall, D.M.4
  • 15
    • 0343416364 scopus 로고    scopus 로고
    • Placebo-controlled study of mycophenolate mofetil used in combination with cyclosporin and corticosteroids for prevention of acute rejection in renal allograft recipients. European Mycophenolate Mofetil Cooperative Study Group
    • Wiesel M, Carl S. Placebo-controlled study of mycophenolate mofetil used in combination with cyclosporin and corticosteroids for prevention of acute rejection in renal allograft recipients. European Mycophenolate Mofetil Cooperative Study Group. J Urol 1998. 159(1):28-33.
    • (1998) J Urol , vol.159 , Issue.1 , pp. 28-33
    • Wiesel, M.1    Carl, S.2
  • 16
    • 0037184814 scopus 로고    scopus 로고
    • Achievement of insulin independence in three consecutive type 1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center
    • Goss JA, Schock AP, Brunicardi FC, Goodpastor SE, Garber AJ, Soltes G, Barth M, Froud T, Alejandro R, Ricordi C. Achievement of insulin independence in three consecutive type 1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center. Transplantation 2002. 74(12):1761-1766.
    • (2002) Transplantation , vol.74 , Issue.12 , pp. 1761-1766
    • Goss, J.A.1    Schock, A.P.2    Brunicardi, F.C.3    Goodpastor, S.E.4    Garber, A.J.5    Soltes, G.6    Barth, M.7    Froud, T.8    Alejandro, R.9    Ricordi, C.10
  • 19
    • 63649092987 scopus 로고    scopus 로고
    • Current status of islet cell transplantation
    • Ichii H, Ricordi C. Current status of islet cell transplantation. J Hepatobiliary Pancreat Surg 2009. 16(2):101-112.
    • (2009) J Hepatobiliary Pancreat Surg , vol.16 , Issue.2 , pp. 101-112
    • Ichii, H.1    Ricordi, C.2
  • 20
    • 0017606227 scopus 로고
    • The use, in diabetic rats and monkeys, of artificial capillary units containing cultured islets of Langerhans (artificial endocrine pancreas)
    • Sun AM, Parisius W, Healy GM, Vacek I, Macmorine HG. The use, in diabetic rats and monkeys, of artificial capillary units containing cultured islets of Langerhans (artificial endocrine pancreas). Diabetes 1977. 26(12):1136-1139.
    • (1977) Diabetes , vol.26 , Issue.12 , pp. 1136-1139
    • Sun, A.M.1    Parisius, W.2    Healy, G.M.3    Vacek, I.4    Macmorine, H.G.5
  • 22
    • 34147193338 scopus 로고    scopus 로고
    • Islet encapsulation: Strategies to enhance islet cell functions
    • Beck J, Angus R, Madsen B, Britt D, Vernon B, Nguyen KT. Islet encapsulation: strategies to enhance islet cell functions. Tissue Eng 2007. 13(3):589-599.
    • (2007) Tissue Eng , vol.13 , Issue.3 , pp. 589-599
    • Beck, J.1    Angus, R.2    Madsen, B.3    Britt, D.4    Vernon, B.5    Nguyen, K.T.6
  • 23
    • 33646735392 scopus 로고    scopus 로고
    • Biological and biomaterial approaches for improved islet transplantation
    • Narang AS, Mahato RI. Biological and biomaterial approaches for improved islet transplantation. Pharmacol Rev 2006. 58(2):194-243.
    • (2006) Pharmacol Rev , vol.58 , Issue.2 , pp. 194-243
    • Narang, A.S.1    Mahato, R.I.2
  • 24
    • 77951627260 scopus 로고    scopus 로고
    • Treatment of diabetes with encapsulated islets
    • de Vos P, Spasojevic M, Faas M. Treatment of diabetes with encapsulated islets. Adv Exp Med Biol 2010. 670:38-53.
    • (2010) Adv Exp Med Biol , vol.670 , pp. 38-53
    • de Vos, P.1    Spasojevic, M.2    Faas, M.3
  • 25
    • 0029128101 scopus 로고
    • Implantable biohybrid artificial organs
    • Colton CK. Implantable biohybrid artificial organs. Cell Transplant 1995. 4(4):415-436.
    • (1995) Cell Transplant , vol.4 , Issue.4 , pp. 415-436
    • Colton, C.K.1
  • 26
    • 0028111040 scopus 로고
    • Protection of encapsulated human islets implanted without immunosuppression in patients with type I or type II diabetes and in nondiabetic control subjects
    • Scharp DW, Swanson CJ, Olack BJ, Latta PP, Hegre OD, Doherty EJ, Gentile FT, Flavin KS, Ansara MF, Lacy PE. Protection of encapsulated human islets implanted without immunosuppression in patients with type I or type II diabetes and in nondiabetic control subjects. Diabetes 1994. 43(9):1167-1170.
    • (1994) Diabetes , vol.43 , Issue.9 , pp. 1167-1170
    • Scharp, D.W.1    Swanson, C.J.2    Olack, B.J.3    Latta, P.P.4    Hegre, O.D.5    Doherty, E.J.6    Gentile, F.T.7    Flavin, K.S.8    Ansara, M.F.9    Lacy, P.E.10
  • 27
    • 0021633384 scopus 로고
    • Islet immunoisolation: The use of hybrid artificial organs to prevent islet tissue rejection
    • Scharp DW, Mason NS, Sparks RE. Islet immunoisolation: the use of hybrid artificial organs to prevent islet tissue rejection. World J Surg 1984. 8(2):221-229.
    • (1984) World J Surg , vol.8 , Issue.2 , pp. 221-229
    • Scharp, D.W.1    Mason, N.S.2    Sparks, R.E.3
  • 28
    • 0030002116 scopus 로고    scopus 로고
    • Local inflammatory response around diffusion chambers containing xenografts. Nonspecific destruction of tissues and decreased local vascularization
    • Brauker J, Martinson LA, Young SK, Johnson RC. Local inflammatory response around diffusion chambers containing xenografts. Nonspecific destruction of tissues and decreased local vascularization. Transplantation 1996. 61(12):1671-1677.
    • (1996) Transplantation , vol.61 , Issue.12 , pp. 1671-1677
    • Brauker, J.1    Martinson, L.A.2    Young, S.K.3    Johnson, R.C.4
  • 32
    • 49249084800 scopus 로고    scopus 로고
    • Preimplantation of an immunoprotective device can lower the curative dose of islets to that of free islet transplantation: Studies in a rodent model
    • Sörenby AK, Kumagai-Braesch M, Sharma A, Hultenby KR, Wernerson AM, Tibell AB. Preimplantation of an immunoprotective device can lower the curative dose of islets to that of free islet transplantation: studies in a rodent model. Transplantation 2008. 86(2):364-366.
    • (2008) Transplantation , vol.86 , Issue.2 , pp. 364-366
    • Sörenby, A.K.1    Kumagai-Braesch, M.2    Sharma, A.3    Hultenby, K.R.4    Wernerson, A.M.5    Tibell, A.B.6
  • 33
    • 65549128625 scopus 로고    scopus 로고
    • Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: Implications for diabetes cell therapies
    • Lee SH, Hao E, Savinov AY, Geron I, Strongin AY, Itkin-Ansari P. Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: implications for diabetes cell therapies. Transplantation 2009. 87(7):983-991.
    • (2009) Transplantation , vol.87 , Issue.7 , pp. 983-991
    • Lee, S.H.1    Hao, E.2    Savinov, A.Y.3    Geron, I.4    Strongin, A.Y.5    Itkin-Ansari, P.6
  • 36
    • 81755187922 scopus 로고    scopus 로고
    • Science and application of skin delivery systems
    • J.W. Wiechers (ed.)
    • Poncelet, D. Science and application of skin delivery systems. J.W. Wiechers (ed.), Allured Publishing Corporation, 2008, p. 251.
    • (2008) Allured Publishing Corporation , pp. 251
    • Poncelet, D.1
  • 37
    • 33646735392 scopus 로고    scopus 로고
    • Biological and biomaterial approaches for improved islet transplantation
    • Narang AS, Mahato RI. Biological and biomaterial approaches for improved islet transplantation. Pharmacol Rev 2006. 58(2):194-243.
    • (2006) Pharmacol Rev , vol.58 , Issue.2 , pp. 194-243
    • Narang, A.S.1    Mahato, R.I.2
  • 39
    • 0019225745 scopus 로고
    • Microencapsulated islets as bioartificial endocrine pancreas
    • Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980. 210(4472):908-910.
    • (1980) Science , vol.210 , Issue.4472 , pp. 908-910
    • Lim, F.1    Sun, A.M.2
  • 40
    • 0029831198 scopus 로고    scopus 로고
    • Factors influencing the adequacy of microencapsulation of rat pancreatic islets
    • de Vos P, De Haan B, Wolters GH, van Schilfgaarde R. Factors influencing the adequacy of microencapsulation of rat pancreatic islets. Transplantation 1996. 62(7):888-893.
    • (1996) Transplantation , vol.62 , Issue.7 , pp. 888-893
    • de Vos, P.1    de Haan, B.2    Wolters, G.H.3    van Schilfgaarde, R.4
  • 42
    • 12344310263 scopus 로고    scopus 로고
    • Inflammatory response to peritoneal implantation of alginate-poly-L-lysine microcapsules
    • Robitaille R, Dusseault J, Henley N, Desbiens K, Labrecque N, Halle JP. Inflammatory response to peritoneal implantation of alginate-poly-L-lysine microcapsules. Biomaterials 2005. 26(19):4119-4127.
    • (2005) Biomaterials , vol.26 , Issue.19 , pp. 4119-4127
    • Robitaille, R.1    Dusseault, J.2    Henley, N.3    Desbiens, K.4    Labrecque, N.5    Halle, J.P.6
  • 43
    • 0031081712 scopus 로고    scopus 로고
    • Effect of the alginate composition on the biocompatibility of alginatepolylysine microcapsules
    • de Vos P, De Haan B, Van Schilfgaarde R. Effect of the alginate composition on the biocompatibility of alginatepolylysine microcapsules. Biomaterials 1997. 18(3):273-278.
    • (1997) Biomaterials , vol.18 , Issue.3 , pp. 273-278
    • de Vos, P.1    de Haan, B.2    van Schilfgaarde, R.3
  • 44
    • 0035814242 scopus 로고    scopus 로고
    • The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules
    • King A, Sandler S, Andersson A. The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules. J Biomed Mater Res 2001. 57(3):374-383.
    • (2001) J Biomed Mater Res , vol.57 , Issue.3 , pp. 374-383
    • King, A.1    Sandler, S.2    Andersson, A.3
  • 45
    • 4143098466 scopus 로고    scopus 로고
    • Causes of limited survival of microencapsulated pancreatic islet grafts
    • de Groot M, Schuurs TA, van Schilfgaarde R. Causes of limited survival of microencapsulated pancreatic islet grafts. J Surg Res 2004.121(1):141-150.
    • (2004) J Surg Res , vol.121 , Issue.1 , pp. 141-150
    • de Groot, M.1    Schuurs, T.A.2    van Schilfgaarde, R.3
  • 46
    • 0345346381 scopus 로고    scopus 로고
    • Transplantation of alginate microcapsules: Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters
    • Kulseng B, Skjak-Braek G, Ryan L, Andersson A, King A, Faxvaag A, Espevik T. Transplantation of alginate microcapsules: generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation 1999. 67(7):978-984.
    • (1999) TransplantaTion , vol.67 , Issue.7 , pp. 978-984
    • Kulseng, B.1    Skjak-Braek, G.2    Ryan, L.3    Andersson, A.4    King, A.5    Faxvaag, A.6    Espevik, T.7
  • 47
    • 33644669226 scopus 로고    scopus 로고
    • An overview on the development of a bio-artificial pancreas as a treatment of insulin-dependent diabetes mellitus
    • Silva AI, de Matos AN, Brons IG, Mateus M. An overview on the development of a bio-artificial pancreas as a treatment of insulin-dependent diabetes mellitus. Med Res Rev 2006. 26(2):181-222.
    • (2006) Med Res Rev , vol.26 , Issue.2 , pp. 181-222
    • Silva, A.I.1    de Matos, A.N.2    Brons, I.G.3    Mateus, M.4
  • 50
    • 0035433196 scopus 로고    scopus 로고
    • Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane
    • Duvivier-Kali VF, Omer A, Parent RJ, O'Neil JJ, Weir GC. Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane. Diabetes 2001. 50(8):1698-1705.
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1698-1705
    • Duvivier-Kali, V.F.1    Omer, A.2    Parent, R.J.3    O'Neil, J.J.4    Weir, G.C.5
  • 53
    • 0037222059 scopus 로고    scopus 로고
    • Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice
    • Omer A, Duvivier-Kali VF, Trivedi N, Wilmot K, Bonner-Weir S, Weir GC. Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice. Diabetes 2003. 52(1):69-75.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 69-75
    • Omer, A.1    Duvivier-Kali, V.F.2    Trivedi, N.3    Wilmot, K.4    Bonner-Weir, S.5    Weir, G.C.6
  • 55
    • 34347406300 scopus 로고    scopus 로고
    • Preoperative evaluation of microencapsulated human parathyroid tissue aids selection of the optimal bioartificial graft for human parathyroid allotransplantation
    • Moskalenko V, Ulrichs K, Kerscher A, Blind E, Otto C, Hamelmann W, Demidchik Y, Timm S. Preoperative evaluation of microencapsulated human parathyroid tissue aids selection of the optimal bioartificial graft for human parathyroid allotransplantation. Transpl Int 2007. 20(8):688-696.
    • (2007) Transpl Int , vol.20 , Issue.8 , pp. 688-696
    • Moskalenko, V.1    Ulrichs, K.2    Kerscher, A.3    Blind, E.4    Otto, C.5    Hamelmann, W.6    Demidchik, Y.7    Timm, S.8
  • 56
    • 0042847215 scopus 로고    scopus 로고
    • Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats
    • Omer A, Keegan M, Czismadia E, de Vos P, van Rooijen N, Bonner-Weir S, Weir GC. Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats. Xenotransplantation 2003. 10(3):240-251.
    • (2003) Xenotransplantation , vol.10 , Issue.3 , pp. 240-251
    • Omer, A.1    Keegan, M.2    Czismadia, E.3    de Vos, P.4    van Rooijen, N.5    Bonner-Weir, S.6    Weir, G.C.7
  • 58
    • 68249095519 scopus 로고    scopus 로고
    • Biocompatibility and immune acceptance of adult porcine islets transplanted intraperitoneally in diabetic NOD mice in calcium alginate poly-L-lysine microcapsules versus barium alginate microcapsules without poly-L-lysine
    • Safley SA, Cui H, Cauffiel S, Tucker-Burden C, Weber CJ. Biocompatibility and immune acceptance of adult porcine islets transplanted intraperitoneally in diabetic NOD mice in calcium alginate poly-L-lysine microcapsules versus barium alginate microcapsules without poly-L-lysine. J Diabetes Sci Technol 2008. 2(5):760-767.
    • (2008) J DiaBetes Sci Technol , vol.2 , Issue.5 , pp. 760-767
    • Safley, S.A.1    Cui, H.2    Cauffiel, S.3    Tucker-Burden, C.4    Weber, C.J.5
  • 61
    • 28444462444 scopus 로고    scopus 로고
    • Impact of residual contamination on the biofunctional properties of purified alginates used for cell encapsulation
    • Tam SK, Dusseault J, Polizu S, Menard M, Halle JP, Yahia L. Impact of residual contamination on the biofunctional properties of purified alginates used for cell encapsulation. Biomaterials 2006. 27(8):1296-1305.
    • (2006) Biomaterials , vol.27 , Issue.8 , pp. 1296-1305
    • Tam, S.K.1    Dusseault, J.2    Polizu, S.3    Menard, M.4    Halle, J.P.5    Yahia, L.6
  • 62
    • 70349847426 scopus 로고    scopus 로고
    • Direct effect of alginate purification on the survival of islets immobilized in alginate-based microcapsules
    • Langlois G, Dusseault J, Bilodeau S, Tam SK, Magassouba D, Halle JP. Direct effect of alginate purification on the survival of islets immobilized in alginate-based microcapsules. Acta Biomater 2009. 5(9):3433-3440.
    • (2009) Acta Biomater , vol.5 , Issue.9 , pp. 3433-3440
    • Langlois, G.1    Dusseault, J.2    Bilodeau, S.3    Tam, S.K.4    Magassouba, D.5    Halle, J.P.6
  • 64
    • 0035191683 scopus 로고    scopus 로고
    • Prevention of morphological changes in alginate microcapsules for islet xenotransplantation
    • Hobbs HA, Kendall WF, Darrabie M, Opara EC. Prevention of morphological changes in alginate microcapsules for islet xenotransplantation. J Investig Med 2001. 49(6):572-575.
    • (2001) J Investig Med , vol.49 , Issue.6 , pp. 572-575
    • Hobbs, H.A.1    Kendall, W.F.2    Darrabie, M.3    Opara, E.C.4
  • 66
    • 3142723475 scopus 로고    scopus 로고
    • Effect of polyethylene glycol grafted onto islet capsules on prevention of splenocyte and cytokine attacks
    • Lee DY, Nam JH, Byun Y. Effect of polyethylene glycol grafted onto islet capsules on prevention of splenocyte and cytokine attacks. J Biomater Sci Polym Ed 2004.15(6):753-766.
    • (2004) J Biomater Sci Polym Ed , vol.15 , Issue.6 , pp. 753-766
    • Lee, D.Y.1    Nam, J.H.2    Byun, Y.3
  • 67
    • 0033010333 scopus 로고    scopus 로고
    • Analysis of the cellular reaction towards microencapsulated xenogeneic islets after intraperitoneal transplantation
    • Siebers U, Horcher A, Brandhorst H, Brandhorst D, Hering B, Federlin K, Bretzel RG, Zekorn T. Analysis of the cellular reaction towards microencapsulated xenogeneic islets after intraperitoneal transplantation. J Mol Med 1999. 77(1):215-218.
    • (1999) J Mol Med , vol.77 , Issue.1 , pp. 215-218
    • Siebers, U.1    Horcher, A.2    Brandhorst, H.3    Brandhorst, D.4    Hering, B.5    Federlin, K.6    Bretzel, R.G.7    Zekorn, T.8
  • 69
    • 0000211882 scopus 로고
    • Protection of xenografts with immunoisolation membranes
    • Martinson L, Pauley R, Brauker J. Protection of xenografts with immunoisolation membranes. Cell Transplant 1995. 3(1):249-256.
    • (1995) Cell Transplant , vol.3 , Issue.1 , pp. 249-256
    • Martinson, L.1    Pauley, R.2    Brauker, J.3
  • 70
    • 0027433162 scopus 로고
    • Macrophage-generated nitric oxide as cytotoxic factor in destruction of alginate-encapsulated islets. Protection by arginine analogs and/or coencapsulated erythrocytes
    • Wiegand F, Kroncke KD, Kolb-Bachofen V. Macrophage-generated nitric oxide as cytotoxic factor in destruction of alginate-encapsulated islets. Protection by arginine analogs and/or coencapsulated erythrocytes. Transplantation 1993. 56(5):1206-1212.
    • (1993) Transplantation , vol.56 , Issue.5 , pp. 1206-1212
    • Wiegand, F.1    Kroncke, K.D.2    Kolb-Bachofen, V.3
  • 71
    • 0033608801 scopus 로고    scopus 로고
    • Co-encapsulation of Sertoli enriched testicular cell fractions further prolongs fish-to-mouse islet xenograft survival
    • Yang H, Wright JR. Co-encapsulation of Sertoli enriched testicular cell fractions further prolongs fish-to-mouse islet xenograft survival. Transplantation 1999. 67(6):815-820.
    • (1999) Transplantation , vol.67 , Issue.6 , pp. 815-820
    • Yang, H.1    Wright, J.R.2
  • 72
    • 0242438799 scopus 로고    scopus 로고
    • Protection of insulin secreting cells from nitric oxide induced cellular damage by crosslinked hemoglobin
    • Chae SY, Lee M, Kim SW, Bae YH. Protection of insulin secreting cells from nitric oxide induced cellular damage by crosslinked hemoglobin. Biomaterials 2004. 25(5):843-850.
    • (2004) Biomaterials , vol.25 , Issue.5 , pp. 843-850
    • Chae, S.Y.1    Lee, M.2    Kim, S.W.3    Bae, Y.H.4
  • 73
    • 0034486027 scopus 로고    scopus 로고
    • Human pancreatic islets transfected to produce an inhibitor of TNF are protected against destruction by human leukocytes
    • Dobson T, Fraga D, Saba C, Bryer-Ash M, Gaber AO, Gerling IC. Human pancreatic islets transfected to produce an inhibitor of TNF are protected against destruction by human leukocytes. Cell Transplant 2000. 9(6):857-865.
    • (2000) Cell Transplant , vol.9 , Issue.6 , pp. 857-865
    • Dobson, T.1    Fraga, D.2    Saba, C.3    Bryer-Ash, M.4    Gaber, A.O.5    Gerling, I.C.6
  • 74
    • 0032830997 scopus 로고    scopus 로고
    • Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro
    • Giannoukakis N, Rudert WA, Ghivizzani SC, Gambotto A, Ricordi C, Trucco M, Robbins PD. Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro. Diabetes 1999. 48(9):1730-1736.
    • (1999) Diabetes , vol.48 , Issue.9 , pp. 1730-1736
    • Giannoukakis, N.1    Rudert, W.A.2    Ghivizzani, S.C.3    Gambotto, A.4    Ricordi, C.5    Trucco, M.6    Robbins, P.D.7
  • 76
    • 70350699457 scopus 로고    scopus 로고
    • Allotransplantation of sulphate glucomannan-alginate barium (SGA) microencapsulated rat islets for the treatment of diabetes mellitus
    • Chen X, Shao W, Chen JB, Zhang L, Matthias C, Shan SG, Qi ZQ. Allotransplantation of sulphate glucomannan-alginate barium (SGA) microencapsulated rat islets for the treatment of diabetes mellitus. Immunol Invest 2009. 38(7):561-571.
    • (2009) Immunol Invest , vol.38 , Issue.7 , pp. 561-571
    • Chen, X.1    Shao, W.2    Chen, J.B.3    Zhang, L.4    Matthias, C.5    Shan, S.G.6    Qi, Z.Q.7
  • 77
    • 0035120134 scopus 로고    scopus 로고
    • Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site
    • Carlsson PO, Palm F, Andersson A, Liss P. Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 2001. 50(3):489-495.
    • (2001) Diabetes , vol.50 , Issue.3 , pp. 489-495
    • Carlsson, P.O.1    Palm, F.2    Andersson, A.3    Liss, P.4
  • 78
    • 0027302243 scopus 로고
    • Transplantation of free and microencapsulated islets in rats: Evidence for the requirement of an increased islet mass for transplantation into the peritoneal site
    • Siebers U, Horcher A, Bretzel RG, Klock G, Zimmermann U, Federlin K, Zekorn T. Transplantation of free and microencapsulated islets in rats: evidence for the requirement of an increased islet mass for transplantation into the peritoneal site. Int J Artif Organs 1993. 16(2):96-99.
    • (1993) Int J Artif Organs , vol.16 , Issue.2 , pp. 96-99
    • Siebers, U.1    Horcher, A.2    Bretzel, R.G.3    Klock, G.4    Zimmermann, U.5    Federlin, K.6    Zekorn, T.7
  • 80
    • 49249084800 scopus 로고    scopus 로고
    • Preimplantation of an immunoprotective device can lower the curative dose of islets to that of free islet transplantation: Studies in a rodent model
    • Sörenby AK, Kumagai-Braesch M, Sharma A, Hultenby KR, Wernerson AM, Tibell AB. Preimplantation of an immunoprotective device can lower the curative dose of islets to that of free islet transplantation: studies in a rodent model. Transplantation 2008. 86(2):364-366.
    • (2008) Transplantation , vol.86 , Issue.2 , pp. 364-366
    • Sörenby, A.K.1    Kumagai-Braesch, M.2    Sharma, A.3    Hultenby, K.R.4    Wernerson, A.M.5    Tibell, A.B.6
  • 81
    • 0029064481 scopus 로고
    • Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro
    • Bellmann K, Wenz A, Radons J, Burkart V, Kleemann R, Kolb H. Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro. J Clin Invest 1995. 95(6):2840-2845.
    • (1995) J Clin Invest , vol.95 , Issue.6 , pp. 2840-2845
    • Bellmann, K.1    Wenz, A.2    Radons, J.3    Burkart, V.4    Kleemann, R.5    Kolb, H.6
  • 82
    • 33846842100 scopus 로고    scopus 로고
    • Amelioration of diabetes by imatinib mesylate (Gleevec): Role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning
    • Hagerkvist R, Sandler S, Mokhtari D, Welsh N. Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning. FASEB 2007. 21(2):618-628.
    • (2007) FASEB , vol.21 , Issue.2 , pp. 618-628
    • Hagerkvist, R.1    Sandler, S.2    Mokhtari, D.3    Welsh, N.4
  • 85
    • 18044371624 scopus 로고    scopus 로고
    • Encapsulation of islets in rough surface, hydroxymethylated polysulfone capillaries stimulates VEGF release and promotes vascularization after transplantation
    • Lembert N, Wesche J, Petersen P, Doser M, Zschocke P, Becker HD, Ammon HP. Encapsulation of islets in rough surface, hydroxymethylated polysulfone capillaries stimulates VEGF release and promotes vascularization after transplantation. Cell Transplant 2005. 14(2-3):97-108.
    • (2005) Cell Transplant , vol.14 , Issue.2-3 , pp. 97-108
    • Lembert, N.1    Wesche, J.2    Petersen, P.3    Doser, M.4    Zschocke, P.5    Becker, H.D.6    Ammon, H.P.7
  • 86
    • 33747886762 scopus 로고    scopus 로고
    • Immobilized microalgal cells as an oxygen supply system for encapsulated pancreatic islets: A feasibility study
    • Bloch K, Papismedov E, Yavriyants K, Vorobeychik M, Beer S, Vardi P. Immobilized microalgal cells as an oxygen supply system for encapsulated pancreatic islets: a feasibility study. Artif Organs 2006. 30(9):715-718.
    • (2006) Artif Organs , vol.30 , Issue.9 , pp. 715-718
    • Bloch, K.1    Papismedov, E.2    Yavriyants, K.3    Vorobeychik, M.4    Beer, S.5    Vardi, P.6
  • 87
    • 77950916877 scopus 로고    scopus 로고
    • Fibroblast growth factor-1 (FGF1) loaded microbeads enhance local capillary neovascularization
    • Moya ML, Garfinkel MR, Liu X, Lucas S, Opara EC, Greisler HP, Brey EM. Fibroblast growth factor-1 (FGF1) loaded microbeads enhance local capillary neovascularization. J Surg Res 2010. 160(2):208-212.
    • (2010) J Surg Res , vol.160 , Issue.2 , pp. 208-212
    • Moya, M.L.1    Garfinkel, M.R.2    Liu, X.3    Lucas, S.4    Opara, E.C.5    Greisler, H.P.6    Brey, E.M.7
  • 88
    • 0025391442 scopus 로고
    • Alginate as immobilization matrix for cells
    • Smidsrød O, Skjak-Braek G. Alginate as immobilization matrix for cells. Trends Biotechnol 1990. 8(3):71-78.
    • (1990) Trends Biotechnol , vol.8 , Issue.3 , pp. 71-78
    • Smidsrød, O.1    Skjak-Braek, G.2
  • 89
    • 0036295460 scopus 로고    scopus 로고
    • Effects of alginate composition on the growth and overall metabolic activity of betaTC3 cells
    • Stabler CL, Sambanis A, Constantinidis I. Effects of alginate composition on the growth and overall metabolic activity of betaTC3 cells. Ann N Y Acad Sci 2002. 961:130-133.
    • (2002) Ann N Y Acad Sci , vol.961 , pp. 130-133
    • Stabler, C.L.1    Sambanis, A.2    Constantinidis, I.3
  • 91
    • 0032791152 scopus 로고    scopus 로고
    • Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells
    • Tiedge M, Lortz S, Munday R, Lenzen S. Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells. Diabetologia 1999. 42(7):849-855.
    • (1999) Diabetologia , vol.42 , Issue.7 , pp. 849-855
    • Tiedge, M.1    Lortz, S.2    Munday, R.3    Lenzen, S.4
  • 92
    • 24344495365 scopus 로고    scopus 로고
    • Rossi C. Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters
    • Giovagnoli S, Luca G, Casaburi I, Blasi P, Macchiarulo G, Ricci M, Calvitti M, Basta G, Calafiore R, Rossi C. Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters. J Control Release 2005. 107(1):65-77.
    • (2005) J Control Release , vol.107 , Issue.1 , pp. 65-77
    • Giovagnoli, S.1    Luca, G.2    Casaburi, I.3    Blasi, P.4    Macchiarulo, G.5    Ricci, M.6    Calvitti, M.7    Basta, G.8    Calafiore, R.9
  • 93
    • 0034154565 scopus 로고    scopus 로고
    • Lipid peroxidation in nicotinamidedeficient and nicotinamide-supplemented rats with streptozotocininduced diabetes
    • Melo SS, Arantes MR, Meirelles MS, Jordao AA Jr, Vannucchi H. Lipid peroxidation in nicotinamidedeficient and nicotinamide-supplemented rats with streptozotocininduced diabetes. Acta Diabetol 2000. 37(1):33-39.
    • (2000) Acta Diabetol , vol.37 , Issue.1 , pp. 33-39
    • Melo, S.S.1    Arantes, M.R.2    Meirelles, M.S.3    Jordao Jr., A.A.4    Vannucchi, H.5
  • 94
    • 0029981458 scopus 로고    scopus 로고
    • Protection of mouse islet isografts from nonspecific inflammatory damage by recipient treatment with nicotinamide and 15deoxyspergualin
    • Kenmochi T, Miyamoto M, Mullen Y. Protection of mouse islet isografts from nonspecific inflammatory damage by recipient treatment with nicotinamide and 15deoxyspergualin. Cell Transplant 1996. 5(1):41-47.
    • (1996) Cell Transplant , vol.5 , Issue.1 , pp. 41-47
    • Kenmochi, T.1    Miyamoto, M.2    Mullen, Y.3
  • 95
    • 70350726217 scopus 로고    scopus 로고
    • Anti-inflammatory peptide-functionalized hydrogels for insulin-secreting cell encapsulation
    • Su J, Hu BH, Lowe WL Jr, Kaufman DB, Messersmith PB. Anti-inflammatory peptide-functionalized hydrogels for insulin-secreting cell encapsulation. Biomaterials 2010. 31(2):308-314.
    • (2010) Biomaterials , vol.31 , Issue.2 , pp. 308-314
    • Su, J.1    Hu, B.H.2    Lowe Jr., W.L.3    Kaufman, D.B.4    Messersmith, P.B.5
  • 97
    • 0032104252 scopus 로고    scopus 로고
    • Synthesis of sulfonylurea conjugated copolymer via PEO spacer and its in vitro short-term bioactivity in insulin secretion from islets of Langerhans
    • Hwang JS, Chae SY, Lee MK, Bae YH. Synthesis of sulfonylurea conjugated copolymer via PEO spacer and its in vitro short-term bioactivity in insulin secretion from islets of Langerhans. Biomaterials 1998. 19(13):1189-1195.
    • (1998) Biomaterials , vol.19 , Issue.13 , pp. 1189-1195
    • Hwang, J.S.1    Chae, S.Y.2    Lee, M.K.3    Bae, Y.H.4
  • 98
    • 85047700090 scopus 로고    scopus 로고
    • Interaction of sulfonylurea conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion
    • Park KH, Kim SW, Bae YH. Interaction of sulfonylurea conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion. J Biomed Mater Res 2001. 55(1):72-78.
    • (2001) J Biomed Mater Res , vol.55 , Issue.1 , pp. 72-78
    • Park, K.H.1    Kim, S.W.2    Bae, Y.H.3
  • 99
    • 11144319307 scopus 로고    scopus 로고
    • Synthesis, bioactivity and specificity of glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets
    • Kim S, Wan Kim S, Bae YH. Synthesis, bioactivity and specificity of glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets. Biomaterials 2005. 26(17):3597-3606.
    • (2005) Biomaterials , vol.26 , Issue.17 , pp. 3597-3606
    • Kim, S.1    Wan, K.S.2    Bae, Y.H.3
  • 103
    • 74549158242 scopus 로고    scopus 로고
    • No evidence of porcine endogenous retrovirus in patients with type 1 diabetes after long-term porcine islet xenotransplantation
    • Valdes-Gonzalez R, Dorantes LM, Bracho-Blanchet E, Rodriguez-Ventura A, White DJ. No evidence of porcine endogenous retrovirus in patients with type 1 diabetes after long-term porcine islet xenotransplantation. J Med Virol 2010. 82(2): 331-334.
    • (2010) J Med Virol , vol.82 , Issue.2 , pp. 331-334
    • Valdes-Gonzalez, R.1    Dorantes, L.M.2    Bracho-Blanchet, E.3    Rodriguez-Ventura, A.4    White, D.J.5
  • 104
    • 0037222059 scopus 로고    scopus 로고
    • Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice
    • Omer A, Duvivier-Kali VF, Trivedi N, Wilmot K, Bonner-Weir S, Weir GC. Survival and maturation of microencapsulated porcine neonatal pancreatic cell clusters transplanted into immunocompetent diabetic mice. Diabetes 2003. 52(1):69-75.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 69-75
    • Omer, A.1    Duvivier-Kali, V.F.2    Trivedi, N.3    Wilmot, K.4    Bonner-Weir, S.5    Weir, G.C.6
  • 105
    • 34250613861 scopus 로고    scopus 로고
    • Differentiation of transplanted microencapsulated fetal pancreatic cells
    • Foster JL, Williams G, Williams LJ, Tuch BE. Differentiation of transplanted microencapsulated fetal pancreatic cells. Transplantation 2007. 83(11):1440-1448.
    • (2007) Transplantation , vol.83 , Issue.11 , pp. 1440-1448
    • Foster, J.L.1    Williams, G.2    Williams, L.J.3    Tuch, B.E.4
  • 106
    • 33947360223 scopus 로고    scopus 로고
    • Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation
    • Elliott RB, Escobar L, Tan PL, Muzina M, Zwain S, Buchanan C. Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. Xenotransplantation 2007. 14(2):157-161.
    • (2007) XenotransPlantation , vol.14 , Issue.2 , pp. 157-161
    • Elliott, R.B.1    Escobar, L.2    Tan, P.L.3    Muzina, M.4    Zwain, S.5    Buchanan, C.6
  • 108
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004. 429(6987):41-46.
    • (2004) Nature , vol.429 , Issue.6987 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 109
    • 9644266753 scopus 로고    scopus 로고
    • Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass
    • Georgia S, Bhushan A. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J Clin Invest 2004. 114(7):963-968.
    • (2004) J Clin Invest , vol.114 , Issue.7 , pp. 963-968
    • Georgia, S.1    Bhushan, A.2
  • 110
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001. 292(5520):1389-1394.
    • (2001) Science , vol.292 , Issue.5520 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay, R.6
  • 113
    • 70449093715 scopus 로고    scopus 로고
    • Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm
    • Chayosumrit M, Tuch B, Sidhu K. Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm. Biomaterials 2010. 31(3):505-514.
    • (2010) Biomaterials , vol.31 , Issue.3 , pp. 505-514
    • Chayosumrit, M.1    Tuch, B.2    Sidhu, K.3
  • 114
    • 33750986489 scopus 로고    scopus 로고
    • Differentiation of encapsulated embryonic stem cells after transplantation
    • Dean SK, Yulyana Y, Williams G, Sidhu KS, Tuch BE. Differentiation of encapsulated embryonic stem cells after transplantation. Transplantation 2006. 82(9):1175-1184.
    • (2006) Transplantation , vol.82 , Issue.9 , pp. 1175-1184
    • Dean, S.K.1    Yulyana, Y.2    Williams, G.3    Sidhu, K.S.4    Tuch, B.E.5
  • 115
    • 33745026210 scopus 로고    scopus 로고
    • Proliferation and differentiation of mouse embryonic stem cells in APA microcapsule: A model for studying the interaction between stem cells and their niche
    • Wang X, Wang W, Ma J, Guo X, Yu X, Ma X. Proliferation and differentiation of mouse embryonic stem cells in APA microcapsule: a model for studying the interaction between stem cells and their niche. Biotechnol Prog 2006. 22(3):791-800.
    • (2006) Biotechnol Prog , vol.22 , Issue.3 , pp. 791-800
    • Wang, X.1    Wang, W.2    Ma, J.3    Guo, X.4    Yu, X.5    Ma, X.6
  • 116
    • 32544451446 scopus 로고    scopus 로고
    • Alginate-PLL microencapsulation: Effect on the differentiation of embryonic stem cells into hepatocytes
    • Maguire T, Novik E, Schloss R, Yarmush M. Alginate-PLL microencapsulation: effect on the differentiation of embryonic stem cells into hepatocytes. Biotechnol Bioeng 2006. 93(3):581-591.
    • (2006) Biotechnol Bioeng , vol.93 , Issue.3 , pp. 581-591
    • Maguire, T.1    Novik, E.2    Schloss, R.3    Yarmush, M.4
  • 118
    • 0034538443 scopus 로고    scopus 로고
    • Three dimensional culture upregulates extracellular matrix protein expression in human liver cell lines a step towards mimicking the liver in vivo?
    • Selden C, Khalil M, Hodgson H. Three dimensional culture upregulates extracellular matrix protein expression in human liver cell lines a step towards mimicking the liver in vivo? Int J Artif Organs 2000. 23(11):774-781.
    • (2000) Int J Artif Organs , vol.23 , Issue.11 , pp. 774-781
    • Selden, C.1    Khalil, M.2    Hodgson, H.3
  • 119
  • 120
    • 28444499313 scopus 로고    scopus 로고
    • Encapsulation of adult human mesenchymal stem cells within collagen-agarose microenvironments
    • Batorsky A, Liao J, Lund AW, Plopper GE, Stegemann JP. Encapsulation of adult human mesenchymal stem cells within collagen-agarose microenvironments. Biotechnol Bioeng 2005. 92(4):492-500.
    • (2005) Biotechnol Bioeng , vol.92 , Issue.4 , pp. 492-500
    • Batorsky, A.1    Liao, J.2    Lund, A.W.3    Plopper, G.E.4    Stegemann, J.P.5
  • 121
    • 77956144899 scopus 로고    scopus 로고
    • Beneficial effects of desferrioxamine on encapsulated human islets in vitro and in vivo study
    • Vaithilingam V, Oberholzer J, Guillemin GJ, Tuch BE. Beneficial effects of desferrioxamine on encapsulated human islets in vitro and in vivo study. Am J Transplant 2010. 10(9):1961-1969.
    • (2010) Am J Transplant , vol.10 , Issue.9 , pp. 1961-1969
    • Vaithilingam, V.1    Oberholzer, J.2    Guillemin, G.J.3    Tuch, B.E.4
  • 123
    • 77953313463 scopus 로고    scopus 로고
    • The humanized NOD/SCID mouse as a preclinical model to study the fate of encapsulated human islets
    • Vaithilingam V, Oberholzer J, Guillemin GJ, Tuch BE. The humanized NOD/SCID mouse as a preclinical model to study the fate of encapsulated human islets. Rev Diabet Stud 2010. 7(1):62-73.
    • (2010) Rev Diabet Stud , vol.7 , Issue.1 , pp. 62-73
    • Vaithilingam, V.1    Oberholzer, J.2    Guillemin, G.J.3    Tuch, B.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.