Biochemical consequences of alginate encapsulation: A NMR study of insulin-secreting cells

Biomaterials

Volumn 27, Issue 12, 2006, Pages 2577-2586

  Simpson, Nicholas E ^a   Grant, Samuel C ^a,b   Gustavsson, Lenita ^c   Peltonen, Vilje Mia ^c   Blackband, Stephen J ^a,b,d   Constantinidis, Ioannis ^a,d  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^d FLORIDA STATE UNIVERSITY   (United States)

Author keywords

13C NMR; Alginate; Isotopomer; Metabolism

Indexed keywords

CELLS; ENCAPSULATION; ENZYMES; INSULIN; METABOLISM; NUCLEAR MAGNETIC RESONANCE;

ALGINATE; ALGINATE-ENCAPSULATED CULTURES; ISOTOPOMER;

BIOCHEMICAL ENGINEERING;

ALGINIC ACID; GLUCOSE; INSULIN;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENCAPSULATION; GLUCOSE INTAKE; INSULIN RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ALGINATES; ANIMALS; BIOARTIFICIAL ORGANS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CITRIC ACID CYCLE; DRUG COMPOUNDING; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PARTICLE SIZE;

ANIMALIA;

EID: 30944459237     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2005.11.042     Document Type: Article

References (50)

1. P. Soon-Shiong, E. Feldman, R. Nelson, T. Heintz, Q. Yao, and Z. Yao Long-term reversal of diabetes by the injection of immunoprotected islets Proc Natl Acad Sci USA 90 1993 5843 5847
2. P. Soon-Shiong, R.E. Heintz, N. Merideth, Q.X. Yao, Z. Yao, and M. Murphy Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation Lancet 343 1994 950 951
3. G. Reach Bioartificial pancreas Diabetic Med 10 1993 105 109
4. F. Lim, and A.M. Sun Microencapsulated islets as bioartificial endocrine pancreas Science 210 1980 908 910
5. R.P. Lanza, and W.L. Chick Immunoisolation: at a turning point Immunol Today 18 1997 135 139
6. R.P. Lanza, and W.L. Chick Transplantation of encapsulated cells and tissues Surgery 121 1997 1 9
7. J.P. Benson, K.K. Papas, I. Constantinidis, and A. Sambanis Towards the development of a bioartificial pancreas: effects of poly l-lysine on alginate beads with βTC3 cells Cell Transplant 6 1997 395 402
8. I. Constantinidis, and A. Sambanis Towards the development of artificial endocrine tissues: 31P NMR spectroscopic studies of immunoisolated, insulin-secreting AtT-20 cells Biotechnol Bioeng 47 1995 431 443
9. 13C NMR study on the effect of alginate/poly l-lysine/alginate entrapment on glucose metabolism by βTC3 mouse insulinoma cells Cell Mol Biol 43 1997 721 729
10. i on the mechanism of insulin secretion in the mouse insulinoma βTC3 cell line Biochem J 326 1997 807 814
11. A. Sambanis, K.K. Papas, P.C. Flanders, R.C. Long Jr., H. Kang, and I. Constantinidis Towards the development of a bioartificial pancreas: immunoisolation and NMR monitoring of mouse insulinomas Cytotechnology 15 1994 351 363
12. B.A. Hicks, R. Stein, S. Efrat, S. Grant, D. Hanahan, and A.A. Demetriou Transplantation of β cells from transgenic mice into nude athymic diabetic rats restores glucose regulation Diabetes Res Clin Pract 14 1991 157 164
13. O. Smidsrod Molecular basis for some physical properties of alginates in gel state J Chem Soc Faraday Trans 57 1974 263 274
14. G. Skjak-Braek, H. Grasdale, and O. Smidsrod Inhomogeneous polysaccharide ionic gels Carbohydrate Polym 10 1989 31 54
15. A. Martinsen, G. Skjak-Braek, and O. Smidsrod Alginate as immobilization material: I. Correlation between chemical and physical properties of alginate gel beads Biotechnol Bioeng 33 1989 79 89
16. O. Smidsrod, and G. Skjak-Braek Alginate as immobilization matrix for cells Trends Biotechnol 8 1990 71 78
17. A. Martinsen, I. Storro, and G. Skjak-Braek Alginate as immobilization material: III. Diffusional properties Biotechnol Bioeng 39 1992 186 194
18. B. Thu, P. Bruheim, T. Espevik, O. Smidsrod, P. Soon-Shiong, and G. Skjak-Braek Alginate polycation microcapsules. I. Interaction between alginate and polycation Biomaterials 17 1996 1031 1040
19. B. Thu, P. Bruheim, T. Espevik, O. Smidsrod, P. Soon-Shiong, and G. Skjak-Braek Alginate polycation mirocapsules. II. Some functional properties Biomaterials 17 1996 1069 1079
20. I. Constantinidis, I. Rask, R.C. Long Jr., and A. Sambanis Effects of alginate composition on the metabolic, secretory, and growth characteristics of entrapped βTC3 mouse insulinoma cells Biomaterials 20 1999 2019 2027
21. C. Stabler, K. Wilks, A. Sambanis, and I. Constantinidis The effects of alginate composition on encapsulated βTC3 cells Biomaterials 22 2001 1301 1310
22. C.L. Stabler, A. Sambanis, and I. Constantinidis Effects of alginate composition on the growth and overall metabolic activity of betaTC3 cells Ann NY Acad Sci 961 2002 130 133
23. 2-guluronic acid interaction on alginate encapsulated βTC3 cells Biomaterials 25 2004 2603 2610
24. G.T. Grant, E.R. Morris, D.A. Rees, P.J.C. Smith, and D. Thom Biological interactions between polysaccharides and divalent cations: the egg-box model FEBS Lett 32 1973 195 198
25. F.M. Matschinsky A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm Diabetes 45 1996 223 241
26. C.B. Newgard, and J.D. McGarry Metabolic coupling factors in pancreatic β-cell signal transduction Annu Rev Biochem 64 1995 689 719
27. M. Prentki New insights into pancreatic β-cell metabolic signaling in insulin secretion Eur J Endocrinol 134 1996 272 286
28. D.H. Lu, H. Mulder, P.Y. Zhao, S.C. Burgess, M.V. Jensen, and S. Kamzolova C-13 NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS) Proc Natl Acad Sci USA 99 2002 2708 2713
29. G.W. Cline, R.L. Lepine, K.K. Papas, R.G. Kibbey, and G.I. Shulman 13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells J Biol Chem 279 2004 44370 44375
30. N.E. Mukundan, P.C. Flanders, I. Constantinidis, K.K. Papas, and A. Sambanis Rates of oxygen uptake by free and alginate entrapped βTC3 insulinoma cells Biochem Biophys Res Commun 210 1995 113 118
31. T.I. Klokk, and J.E. Melvik Controlling the size of alginate gel beads by use of a high electrostatic potential J Microencapsul 19 2002 415 424
32. 13C-NMR spectroscopy J Biol Chem 263 1988 6964 6971
33. 13C isotopomer analysis of complex metabolic conditions: substrate oxidation, multiple pyruvate cycles, and gluconeogenesis Metab Eng 6 2004 12 24
34. 13C NMR study. Diabetologia 2005; submitted for review.
35. A.G. Webb, and S.C. Grant Signal-to-noise and magnetic susceptibility trade-offs in solenoidal microcoils for NMR J Magn Reson B 113 1996 83 87
36. 2 measurements using NMR microscopy J Magn Reson B 109 1995 66 69
37. P.L. Pedersen Tumor mitochondria and the bioenergetics of cancer cells F. Homburger Progress in tumor research vol. 22 1978 S. Karger Basel 190 274
38. N. Sekine, V. Cirulli, R. Regazzi, L.J. Brown, E. Gine, and J. Tamarit-Rodriguez Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing J Biol Chem 269 1994 4895 4902
39. E. Tziampazis, and A. Sambanis Tissue engineering of a bioartificial pancreas: modeling the cell environment and device function Biotechnol Progr 11 1995 115 126
40. K.K. Papas, R.C. Long Jr., I. Constantinidis, and A. Sambanis Effects of oxygen on the metabolic and secretory activities of βTC3 monolayers Biochim Biophys Acta 1291 1996 163 166
41. K.K. Papas, R.C. Long Jr., I. Constantinidis, and A. Sambanis Development of a bioartificial pancreas: II. Effects of oxygen on long-term entrapped bTC3 cell cultures Biotechnol Bioeng 66 1999 231 237
42. K.K. Papas, R.C. Long Jr., A. Sambanis, and I. Constantinidis Effects of short-term hypoxia on a bioartificial pancreatic construct Cell Transplant 9 2000 415 422
43. F.M. Matschinsky, and J.E. Ellerman Metabolism of glucose in the islets of Langerhans J Biol Chem 243 1968 2730 2736
44. W.J. Malaisse, A. Sener, A. Herchuelz, and J.C. Hutton Insulin release: the fuel hypothesis Metabolism 28 1979 373 385
45. P. Hildebrandt, P. Sejrsen, S.L. Nielsen, K. Birch, and L. Sestoft Diffusion and polymerization determines the insulin absorption from subcutaneous tissue in diabetic patients Scand J Clin Lab Invest 45 1985 685 690
46. S. Sakai, T. Ono, H. Ijima, and K. Kawakami In vitro and in vivo evaluation of alginate/sol-gel synthesized aminopropyl-silicate/alginate membrane for bioartificial pancreas Biomaterials 23 2002 4177 4183
47. K.K. Papas, R.C. Long Jr., I. Constantinidis, and A. Sambanis Development of a bioartificial pancreas: I. Long-term propagation and basal and induced secretion from entrapped bTC3 cell cultures Biotechnol Bioeng 66 1999 219 230
48. R.M. Sutherland Cell and environment interactions in tumor microregions: the multicell spheroid model Science 240 1988 177 184
49. L.O. Sillerud, J.P. Freyer, M. Neeman, and M.A. Mattingly Proton NMR microscopy of multicellular tumor spheroid morphology Magn Reson Med 16 1990 380 389
50. M.J. MacDonald, L.A. Fahien, L.J. Brown, N.M. Hasan, J.D. Buss, and M.A. Kendrick Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion Am J Physiol Endocrinol Metab 288 2005 E1 E15