Transplantation of alginate microcapsules: Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters

Transplantation

Volumn 67, Issue 7, 1999, Pages 978-984

  Kulseng, Bård ^a,c   Skjåk BrÆk, Gudmund ^a   Ryan, Liv ^a   Andersson, Arne ^b   King, Aileen ^b   Faxvaag, Arild ^a   Espevik, Terje ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b UPPSALA UNIVERSITY   (Sweden)

^c Inst Cancer Res/Molecular Biology   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; BOVINE SERUM ALBUMIN; CYCLOSPORIN; GULURONIC ACID; IMMUNOLOGICAL ADJUVANT; MANNURONIC ACID; PANCREAS ISLET CELL ANTIBODY; POLYLYSINE; SUGAR ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNOGENICITY; IMMUNOSUPPRESSIVE TREATMENT; MICROCAPSULE; MICROENCAPSULATION; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PERMEABILITY; PLAQUE FORMING CELL; PRIORITY JOURNAL; RAT; SHEEP ERYTHROCYTE; SWINE;

ADJUVANTS, IMMUNOLOGIC; ALGINATES; ANIMALS; ANTIBODIES; BIOCOMPATIBLE MATERIALS; CAPSULES; CELL AGGREGATION; FEMALE; FETAL TISSUE TRANSPLANTATION; FETUS; GLUCURONIC ACID; HEXURONIC ACIDS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; RATS; RATS, WISTAR; SERUM ALBUMIN, BOVINE; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 0345346381     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199904150-00008     Document Type: Article

References (26)

1. Thu B, Bruheim P, Espevik T, Smidsrod O, Soon Shiong P, Skjak Braek G. Alginate polycation microcapsules. I. Interaction between alginate and polycation. Biomaterials 1996; 17: 1031.
2. Kulseng B, Thu B, Espevik T, Skjåk-Bræk G. Alginate poylysine microcapsules as immune barrier: permeability of cytokines and immunoglobulins over the capsule membrane. Cell Transplant 1997; 6: 387.
3. Espevik T, Otterlei M, Skjak Braek G, Ryan L, Wright SD, Sundan A. The involvement of CD14 in stimulation of cytokine production by uronic acid polymers. Eur J Immunol 1993; 23: 255.
4. Otterlei M, Ostgaard K, Skjak Braek G, Smidsrod O, Soon Shiong P, Espevik T. Induction of cytokine production from human monocytes stimulated with alginate. J Immunother 1991; 10: 286.
5. Grasdalen H. High-field 1 h-NMR spectroscopy of alginate: sequential structure and linkage conformations. Carbohydr Polym 1983; 118: 255.
6. Martinsen A, Skjåk-Bræk G, Smidsrcd O, Zanetti F, Paoletti S. Comparison of different methods for determination of molecular weight and weight distribution of alginates. Carbohydr Polym 1991; 15: 171.
7. Skjak Braek G, Grasdalen H, Larsen B. Monomer sequence and acetylation pattern in some bacterial alginates. Carbohydr Res 1986; 154: 239.
8. Korsgren O, Sandler S, Landstrom AS, Jansson L, Andersson A. Large-scale production of fetal porcine pancreatic islet-like cell clusters: an experimental tool for studies of islet cell differentiation and xenotransplantation. Transplantation 1988; 45: 509.
9. Martinsen A, Skjåk-Bræk G, Smidsrd O. Alginate as immobilization material. I. Correlation between chemical and physical properties of alginate gel beads. Biotechn Bioeng 1989; 33: 79.
10. Jahr TG, Ryan L, Sundan A, Lichenstein HS, Skjak Braek G, Espevik T. Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/permeability-increasing factor. Infect Immun 1997; 65: 89.
11. Faxvaag A, Espevik T, Dalen A. An immunosuppressive murine leukaemia virus induces a Th1→Th2 switch and abrogates the IgM antibody response to sheep erythrocytes by suppressing the production of IL-2. Clin Exp Immunol 1995; 102: 487.
12. Cunningham AJ, Szenberg A. Further improvements in the plaque technique for detecting single antibody-forming cells. Immunology 1967; 14: 599.
13. Naim JO, Lanzafame RJ, van Oss CJ. The adjuvant effect of silicone-gel on antibody formation in rats. Immunol Invest 1993; 22: 151.
14. Sun AM, O'Shea GM, Goosen MF. Injectable microencapsulated islet cells as a bioartificial pancreas. Appl Biochem Biotechnol 1984; 10: 87.
15. Thu B, Bruheim P, Espevik T, Smidsrod O, Soon Shiong P, Skjak Braek G. Alginate polycation microcapsules. II. Some functional properties. Biomaterials 1996; 17: 1069.
16. Kulseng B, Skjak Braek G, Folling I, Espevik T. TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide. Scand J Immunol 1996; 43: 335.
17. Weber CJ, Hagler MK, Chryssochoos JT, et al. CTLA4-Ig prolongs survival of microencapsulated neonatal porcine islet xenografts in diabetic NOD mice. Cell Transplant 1997; 6: 505.
18. LIU Y. Is CTLA-4 a negative regulator for T-cell activation? Immunol Today 1997; 18: 569.
19. Lanza RP, Beyer AM, Chick WL. Xenogenic humoral responses to islets transplanted in biohybrid diffusion chambers. Transplantation 1994; 57: 1371.
20. Shiroki R, Mohanakumar T, Scharp DW. Analysis of the serological and cellular sensitization induced by encapsulated human islets transplantation in type I and type II diabetes patients. Cell Transplant 1995; 4: 535.
21. Sun Y, Ma X, Zhou D, Vacek I, Sun AM. Normalization of diabetes in spontaneously diabetic cynomolgus monkeys by xenografts of microencapsulated porcine islets without immunosuppression. J Clin Invest 1996; 98: 1417.
22. Lanza RP, Kuhtreiber WM, Ecker D, Staruk JE, Chick WL. Xenotransplantation of porcine and bovine islets without immunosuppression using uncoated alginate microspheres. Transplantation 1995; 59: 1377.
23. Arakawa H, Andius P, Kawikova I, Skoogh BE, Lofdahl CG, Lotvall J. Treatment with cyclosporin A during sensitization with trimellitic anhydride attenuates the airway responses to allergen challenge three weeks later. Eur J Pharmacol 1994; 252: 313.
24. Lanza RP, Kuhtreiber WM, Ecker DM, Marsh JP, Staruk JE, Chick WL. A simple method for xenotransplanting cells and tissues into rats using uncoated alginate microreactors. Transplant Proc 1996; 28: 835.
25. Theofilopoulos AN, Dixon FJ. The biology and detection of immune complexes. Adv Immunol 1979; 28: 89.
26. Wilson CB, Dixon FJ. Quantitation of acute and chronic serum sickness in the rabbit. J Exp Med 1979; 134: 7.