ShRNA-mediated silencing of Gli2 gene inhibits proliferation and sensitizes human hepatocellular carcinoma cells towards TRAIL-induced apoptosis

Journal of Cellular Biochemistry

Volumn 112, Issue 11, 2011, Pages 3140-3150

  Zhang, Dawei ^a   Liu, Jianping ^a   Wang, Yang ^a   Chen, Jie ^a   Chen, Tao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

APOPTOSIS; Gli2; HCC; shRNA; TRAIL

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYCLIN D1; CYCLIN E; FLICE INHIBITORY PROTEIN; PROTEIN BCL 2; PROTEIN P21; SHORT HAIRPIN RNA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

BASE SEQUENCE; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DNA PRIMERS; FLOW CYTOMETRY; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIVER NEOPLASMS; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

ERINACEIDAE;

EID: 80055018393     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23240     Document Type: Article

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