Drug-induced permeabilization of parasite's digestive vacuole is a key trigger of programmed cell death in Plasmodium falciparum

Cell Death and Disease

Volumn 2, Issue 10, 2011, Pages

  Ch'ng, J H ^a   Liew, K ^a   Goh, A S P ^a   Sidhartha, E ^a   Tan, K S W ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Chloroquine; Digestive vacuole; Lysosomal membrane permeabilization; Malaria; Plasmodium falciparum; Programmed cell death

Indexed keywords

CALCIUM ION; CHLOROQUINE; COUMARIN; ANTIMALARIAL AGENT;

ANTIMALARIAL ACTIVITY; APOPTOSIS; ARTICLE; CELL PERMEABILIZATION; CELL VACUOLE; CONTROLLED STUDY; DIGESTIVE SYSTEM; DIGESTIVE VACUOLE MEMBRANE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DEGRADATION; FLOW CYTOMETRY; IC 50; LYSOSOME; MAMMAL CELL; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ELECTRON MICROSCOPY; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN MICROARRAY; SIGNAL TRANSDUCTION;

MAMMALIA; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON; PLASMODIUM FALCIPARUM; PROTEIN ARRAY ANALYSIS; SIGNAL TRANSDUCTION; VACUOLES;

EID: 80055012546     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.97     Document Type: Article

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