Effect of penetration enhancers and iontophoresis on the FT-IR spectroscopy and LHRH permeability through porcine skin

Journal of Controlled Release

Volumn 47, Issue 1, 1997, Pages 81-89

  Bhatia, Kuljit S ^a   Gao, Shen ^a   Singh, Jagdish ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Fourier transform infrared spectroscopy; Iontophoresis; Oleic acid; Penetration enhancer; Transdermal drug delivery

Indexed keywords

ALCOHOL; GONADORELIN; OLEIC ACID; PENETRATION ENHANCING AGENT; PROPYLENE GLYCOL; SKIN LIPID;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG METABOLISM; EPIDERMIS; INFRARED SPECTROSCOPY; IONTOPHORESIS; NONHUMAN; PRIORITY JOURNAL; SKIN PENETRATION; SKIN PERMEABILITY; SWINE; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0031003156     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(96)01618-5     Document Type: Article

References (30)

1. J. Hadgraft and R.H. Guy, Transdermal Drug Delivery-Developmental Issues and Research Initiatives, Marcel Dekker, New York, 1989.
2. R.R. Burnette and D. Marrero, Comparison between the iontophoretic and passive transport of thyrotropin releasing hormone across excised nude mouse skin. J. Pharm. Sci. 75 (1986) 738-743.
3. J. Singh and H.I. Maibach, Topical iontophoretic drug delivery in vivo: historical development, devices and future perspectives. Dermatology 187 (1993) 235-238.
4. J. Singh and M.S. Roberts, Iontophoretic transport of amphoteric solutes through human skin: p-aminobenzoic acid and amphotericin. Pharm. Sci. 1 (1995) 223-226.
5. S. Singh, S.B. Jayaswal, S.N. Upadhyay and J. Singh, Iontophoretic delivery of propranolol hydrochloride through human epidermis. J. Control. Release 18 (1992) 167-172.
6. L.L. Miller, G.A. Kolaskie and J.E. Riviere, Transdermal iontophoresis of gonadotropin releasing hormone (LHRH) and two analogues. J. Pharm. Sci. 79 (1990) 490-493.
7. B. Kari, Control of blood glucose levels in alloxan-diabetic rats by iontophoresis of insulin. Diabetes 35 (1986) 217-221.
8. M.H. Heit, P.L. Williams, F.L. Jayes, S.K. Chang and J.E. Riviere, Transdermal iontophoretic peptide delivery: in vitro and in vivo studies with lutenizing hormone releasing hormone. J. Pharm. Sci. 82 (1993) 240-243.
9. A.C. Wlliams and B.W. Barry, Skin absorption enhancers, Crit. Rev. Ther. Drug Carrier Syst. 9 (1992) 305-353.
10. J. Singh and S. Singh, in: C. Surber, P. Elsner and A.J. Bircher (Eds.) Exogenous Dermatology: Advances in Skin Related Allergology, Bioengineering, Pharmacology and Toxicology, Karger, Basel, 1995, pp. 179-183.
11. S. Ganga, P. Rama Rao and J. Singh, Effect of Azone® on the iontophoretic transdermal delivery of metoprolol tartarate through human epidermis in vitro. J. Control. Release 42 (1996) 57-64.
12. V. Srinivasan. M.H. Su, W.I. Higuchi and C.R. Behl, Iontophoresis of polypeptides: effect of ethanol pretreatment of human skin. J. Pharm. Sci. 79 (1990) 588-591.
13. V. Srinivasan, W.I. Higuchi, S.M. Sims, A.H. Ghanem and C.R. Behl, Transdermal iontophoretic drug delivery: mechanistic analysis and application to polypeptide delivery. J. Pharm. Sci. 78 (1989) 370-375.
14. H.E. Bodde, I. Van den Brink, H.K. Koerten and F.H.N. de Haan, Visualization of in vitro percutaneous penetration of mercuric chloride transport through intercellular space versus cellular uptake through desmosomes. J. Control. Release 15 (1991) 227-236.
15. J. Singh and K.S. Bhatia, Topical iontophoretic drug delivery: pathways, principles, factors and skin irritation. Med. Res. Rev. 16 (1996) 285-296.
16. G.M. Golden, D.B. Guzek, R.R. Harris, J.E. McKie and R.O. Potts, Lipid thermotropic transitions in human stratum corneum. J. Invest. Dermatol. 86 (1986) 255-259.
17. K. Knutson, R.O. Potts, D.B. Guzek, G.M. Golden, W.J. Lambert, J.E. McKie and W.I. Higuchi, Macro and molecular physical-chemical considerations in understanding drug transport in the stratum corneum. J. Control. Release 2 (1985) 67-87.
18. R.J. Santen, Therapeutic applications of luteinizing hormone releasing hormone and its analogs, G.B. Jr. Cutler, (Modera-ter). Ann. Intern. Med. 102 (1985) 643-657.
19. K.S. Bhatia and J. Singh, Pig ear skin as a model for predicting percutaneous absorption in man. Pharm. Sci. 2 (1996) 275-276.
20. R.J. Scheuplein, The physiology and pathophysiology of skin, in: A. Jarret (Ed.), Academic press. New York, 5, 1978, pp. 1693-1730.
21. N.A. Mazer, Pharmacokinetic and pharmacodynamic aspects of polypeptide delivery. J. Control. Release 11 (1990) 343-356.
22. M.-y. F. Lu, Lee and G.S. Rao, Percutaneous absorption enhancement of leuprolide. Pharm. Res. 9 (1992) 1575-1579.
23. D. Bommi Bommannan, J. Tamada, L. Leung and R.O. Potts, Effect of electroporation on transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH) in vitro. Pharm. Res. 11 (1994) 1809-1814.
24. R.L. Chan, M.L. Henzl, M.E. LePage, J. LaFargue, C.A. Nerenberg, S. Anik and M.D. Chaplin, Absorption and metabolism of nafarelin, a potent agonist of gonadotropin-releasing hormone. Clin. Pharmacol. Ther. 44 (1988) 275-282.
25. S. Singh and J. Singh, Transdermal delivery of drugs by phonophoresis: a review. Drug Design Delivery 5 (1990) 259-265.
26. H.L. Casal and H.H. Mantsch, Polymeric phase behavior of phospholipid membranes studied by infrared spectroscopy. Biochim. Biophys. Acta 779 (1984) 381-401.
27. R.O. Potts, G.M. Golden, M.L. Francoeur, V.H.W. Mak and R.H. Guy, Mechanism and enhancement of solute transport across the stratum corneum. J. Control. Release 15 (1991) 249-260.
28. M.L. Francoeur, G.M. Golden and R.O. Potts, Oleic acid: its effects on stratum corneum in relation to (trans)dermal drug delivery. Pharm. Res. 7, 621-627.
29. A. Naik, Louk A.R.M. Pechtold, R.O. Potts and R.H. Guy, Mechanism of oleic acid-induced skin penetration enhancement in vivo in humans. J. Control. Release 37 (1995) 299-306.
30. M.J. Clancy, J. Corish and O.I. Corrigan, A comparison of the effects of electric current and penetration enhancers on the properties of human skin using spectroscopic (FT-IR) and calorimetric (DSC) methods. Int. J. Pharm. 105 (1994) 47-56.