메뉴 건너뛰기




Volumn 60, Issue 11, 2011, Pages 1610-1619

Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID A PROTEIN; CARISOPRODOL; CELL MARKER; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLYCOGEN; INSULIN; INTERLEUKIN 6; LEPTIN RECEPTOR; MOLECULAR MARKER; PHOSPHOENOLPYRUVATE CARBOXYLASE; PYRUVIC ACID; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHR; TRIACYLGLYCEROL;

EID: 80054997743     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.04.004     Document Type: Article
Times cited : (11)

References (49)
  • 1
    • 0034625547 scopus 로고    scopus 로고
    • Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes
    • J.C. Pickup, G.D. Chusney, S.M. Thomas, and D. Burt Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes Life Sci 67 2000 291 300
    • (2000) Life Sci , vol.67 , pp. 291-300
    • Pickup, J.C.1    Chusney, G.D.2    Thomas, S.M.3    Burt, D.4
  • 2
    • 0035908632 scopus 로고    scopus 로고
    • C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
    • A.D. Pradhan, J.E. Manson, N. Rifai, J.E. Buring, and P.M. Ridker C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus JAMA 286 2001 327 334
    • (2001) JAMA , vol.286 , pp. 327-334
    • Pradhan, A.D.1    Manson, J.E.2    Rifai, N.3    Buring, J.E.4    Ridker, P.M.5
  • 3
    • 0242268894 scopus 로고    scopus 로고
    • Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
    • P.J. Klover, T.A. Zimmers, L.G. Koniaris, and R.A. Mooney Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice Diabetes 52 2003 2784 2789
    • (2003) Diabetes , vol.52 , pp. 2784-2789
    • Klover, P.J.1    Zimmers, T.A.2    Koniaris, L.G.3    Mooney, R.A.4
  • 4
    • 0036894360 scopus 로고    scopus 로고
    • Interleukin-6 induces cellular insulin resistance in hepatocytes
    • J.J. Senn, P.J. Klover, I.A. Nowak, and R.A. Mooney Interleukin-6 induces cellular insulin resistance in hepatocytes Diabetes 51 2002 3391 3399
    • (2002) Diabetes , vol.51 , pp. 3391-3399
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Mooney, R.A.4
  • 5
    • 0037853260 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
    • J.J. Senn, P.J. Klover, I.A. Nowak, T.A. Zimmers, L.G. Koniaris, and R.W. Furlanetto Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes J Biol Chem 278 2003 13740 13746
    • (2003) J Biol Chem , vol.278 , pp. 13740-13746
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Zimmers, T.A.4    Koniaris, L.G.5    Furlanetto, R.W.6
  • 6
    • 0035930605 scopus 로고    scopus 로고
    • SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice
    • B. Emanuelli, P. Peraldi, C. Filloux, C. Chavey, K. Freidinger, and D.J. Hilton SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice J Biol Chem 276 2001 47944 47949
    • (2001) J Biol Chem , vol.276 , pp. 47944-47949
    • Emanuelli, B.1    Peraldi, P.2    Filloux, C.3    Chavey, C.4    Freidinger, K.5    Hilton, D.J.6
  • 7
    • 4344698092 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients
    • J. Rieusset, K. Bouzakri, E. Chevillotte, N. Ricard, D. Jacquet, and J.P. Bastard Suppressor of cytokine signaling 3 expression and insulin resistance in skeletal muscle of obese and type 2 diabetic patients Diabetes 53 2004 2232 2241
    • (2004) Diabetes , vol.53 , pp. 2232-2241
    • Rieusset, J.1    Bouzakri, K.2    Chevillotte, E.3    Ricard, N.4    Jacquet, D.5    Bastard, J.P.6
  • 8
    • 2942628012 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms
    • K. Ueki, T. Kondo, and C.R. Kahn Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms Mol Cell Biol 24 2004 5434 5446
    • (2004) Mol Cell Biol , vol.24 , pp. 5434-5446
    • Ueki, K.1    Kondo, T.2    Kahn, C.R.3
  • 10
    • 3042721664 scopus 로고    scopus 로고
    • Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction
    • M.A. Febbraio, N. Hiscock, M. Sacchetti, C.P. Fischer, and B.K. Pedersen Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction Diabetes 53 2004 1643 1648
    • (2004) Diabetes , vol.53 , pp. 1643-1648
    • Febbraio, M.A.1    Hiscock, N.2    Sacchetti, M.3    Fischer, C.P.4    Pedersen, B.K.5
  • 11
    • 23044499225 scopus 로고    scopus 로고
    • Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt
    • C. Weigert, A.M. Hennige, K. Brodbeck, H.U. Haring, and E.D. Schleicher Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt Am J Physiol Endocrinol Metab 289 2005 E251 E257
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Weigert, C.1    Hennige, A.M.2    Brodbeck, K.3    Haring, H.U.4    Schleicher, E.D.5
  • 12
    • 33751501694 scopus 로고    scopus 로고
    • Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle
    • L. Al-Khalili, K. Bouzakri, S. Glund, F. Lonnqvist, H.A. Koistinen, and A. Krook Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle Mol Endocrinol 20 2006 3364 3375
    • (2006) Mol Endocrinol , vol.20 , pp. 3364-3375
    • Al-Khalili, L.1    Bouzakri, K.2    Glund, S.3    Lonnqvist, F.4    Koistinen, H.A.5    Krook, A.6
  • 13
    • 33750859187 scopus 로고    scopus 로고
    • Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
    • A.L. Carey, G.R. Steinberg, and S.L. Macaulay Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase Diabetes 55 2006 2688 2697
    • (2006) Diabetes , vol.55 , pp. 2688-2697
    • Carey, A.L.1    Steinberg, G.R.2    MacAulay, S.L.3
  • 14
    • 2942748289 scopus 로고    scopus 로고
    • AMPK activity is diminished in tissues of IL-6 knockout mice: The effect of exercise
    • M. Kelly, C. Keller, and P.R. Avilucea AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise Biochem Biophys Res Commun 320 2004 449 454
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 449-454
    • Kelly, M.1    Keller, C.2    Avilucea, P.R.3
  • 16
    • 0031895668 scopus 로고    scopus 로고
    • Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running
    • K. Ostrowski, T. Rohde, M. Zacho, S. Asp, and B.K. Pedersen Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running J Physiol 508 Pt 3 1998 949 953
    • (1998) J Physiol , vol.508 , Issue.PART 3 , pp. 949-953
    • Ostrowski, K.1    Rohde, T.2    Zacho, M.3    Asp, S.4    Pedersen, B.K.5
  • 17
    • 0642364997 scopus 로고    scopus 로고
    • Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise
    • M. Penkowa, C. Keller, P. Keller, S. Jauffred, and B.K. Pedersen Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise FASEB J 17 2003 2166 2168
    • (2003) FASEB J , vol.17 , pp. 2166-2168
    • Penkowa, M.1    Keller, C.2    Keller, P.3    Jauffred, S.4    Pedersen, B.K.5
  • 18
    • 58149345626 scopus 로고    scopus 로고
    • Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle
    • I. Nieto-Vazquez, S. Fernandez-Veledo, C. de Alvaro, and M. Lorenzo Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle Diabetes 57 2008 3211 3221
    • (2008) Diabetes , vol.57 , pp. 3211-3221
    • Nieto-Vazquez, I.1    Fernandez-Veledo, S.2    De Alvaro, C.3    Lorenzo, M.4
  • 20
    • 77957661299 scopus 로고    scopus 로고
    • Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
    • V.B. Matthews, T.L. Allen, and S. Risis Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance Diabetologia 53 2010 2431 2441
    • (2010) Diabetologia , vol.53 , pp. 2431-2441
    • Matthews, V.B.1    Allen, T.L.2    Risis, S.3
  • 21
    • 33745315308 scopus 로고    scopus 로고
    • Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice
    • D. Chida, T. Osaka, O. Hashimoto, and Y. Iwakura Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice Diabetes 55 2006 971 977
    • (2006) Diabetes , vol.55 , pp. 971-977
    • Chida, D.1    Osaka, T.2    Hashimoto, O.3    Iwakura, Y.4
  • 22
    • 3042739678 scopus 로고    scopus 로고
    • Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: Absence of development of age-related obesity
    • G.B. Di Gregorio, L. Hensley, T. Lu, G. Ranganathan, and P.A. Kern Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity Am J Physiol Endocrinol Metab 287 2004 E182 E187
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Di Gregorio, G.B.1    Hensley, L.2    Lu, T.3    Ranganathan, G.4    Kern, P.A.5
  • 23
    • 51349133256 scopus 로고    scopus 로고
    • Interleukin-6 regulates pancreatic alpha-cell mass expansion
    • H. Ellingsgaard, J.A. Ehses, and E.B. Hammar Interleukin-6 regulates pancreatic alpha-cell mass expansion Proc Natl Acad Sci U S A 105 2008 13163 13168
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13163-13168
    • Ellingsgaard, H.1    Ehses, J.A.2    Hammar, E.B.3
  • 24
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
    • D.L. Coleman Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice Diabetologia 14 1978 141 148
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 25
    • 23044468612 scopus 로고    scopus 로고
    • Interleukin-6 depletion selectively improves hepatic insulin action in obesity
    • P.J. Klover, A.H. Clementi, and R.A. Mooney Interleukin-6 depletion selectively improves hepatic insulin action in obesity Endocrinology 146 2005 3417 3427
    • (2005) Endocrinology , vol.146 , pp. 3417-3427
    • Klover, P.J.1    Clementi, A.H.2    Mooney, R.A.3
  • 26
    • 3142723189 scopus 로고    scopus 로고
    • Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
    • K. Ueki, T. Kondo, Y.H. Tseng, and C.R. Kahn Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse Proc Natl Acad Sci U S A 101 2004 10422 10427
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10422-10427
    • Ueki, K.1    Kondo, T.2    Tseng, Y.H.3    Kahn, C.R.4
  • 27
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248 254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 28
    • 0031441286 scopus 로고    scopus 로고
    • Troglitazone action is independent of adipose tissue
    • C.F. Burant, S. Sreenan, and K. Hirano Troglitazone action is independent of adipose tissue J Clin Invest 100 1997 2900 2908
    • (1997) J Clin Invest , vol.100 , pp. 2900-2908
    • Burant, C.F.1    Sreenan, S.2    Hirano, K.3
  • 29
    • 0035900778 scopus 로고    scopus 로고
    • Foxa3 (hepatocyte nuclear factor 3 gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast
    • W. Shen, L.M. Scearce, J.E. Brestelli, N.J. Sund, and K.H. Kaestner Foxa3 (hepatocyte nuclear factor 3 gamma) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast J Biol Chem 276 2001 42812 42817
    • (2001) J Biol Chem , vol.276 , pp. 42812-42817
    • Shen, W.1    Scearce, L.M.2    Brestelli, J.E.3    Sund, N.J.4    Kaestner, K.H.5
  • 30
    • 34547906123 scopus 로고    scopus 로고
    • Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1
    • J.T. Rodgers, and P. Puigserver Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1 Proc Natl Acad Sci U S A 104 2007 12861 12866
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12861-12866
    • Rodgers, J.T.1    Puigserver, P.2
  • 31
    • 0036853886 scopus 로고    scopus 로고
    • Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
    • K. Miyake, W. Ogawa, M. Matsumoto, T. Nakamura, H. Sakaue, and M. Kasuga Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver J Clin Invest 110 2002 1483 1491
    • (2002) J Clin Invest , vol.110 , pp. 1483-1491
    • Miyake, K.1    Ogawa, W.2    Matsumoto, M.3    Nakamura, T.4    Sakaue, H.5    Kasuga, M.6
  • 32
    • 5344252327 scopus 로고    scopus 로고
    • Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
    • J. Lin, P.H. Wu, and P.T. Tarr Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice Cell 119 2004 121 135
    • (2004) Cell , vol.119 , pp. 121-135
    • Lin, J.1    Wu, P.H.2    Tarr, P.T.3
  • 33
    • 33750588944 scopus 로고    scopus 로고
    • Nutrient control of phosphorylation and translocation of Foxo1 in C57BL/6 and db/db mice
    • H. Aoyama, H. Daitoku, and A. Fukamizu Nutrient control of phosphorylation and translocation of Foxo1 in C57BL/6 and db/db mice Int J Mol Med 18 2006 433 439
    • (2006) Int J Mol Med , vol.18 , pp. 433-439
    • Aoyama, H.1    Daitoku, H.2    Fukamizu, A.3
  • 34
    • 0037067570 scopus 로고    scopus 로고
    • Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss
    • P. Cohen, M. Miyazaki, and N.D. Socci Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss Science 297 2002 240 243
    • (2002) Science , vol.297 , pp. 240-243
    • Cohen, P.1    Miyazaki, M.2    Socci, N.D.3
  • 35
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • D. Cai, M. Yuan, D.F. Frantz, P.A. Melendez, L. Hansen, and J. Lee Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB Nat Med 11 2005 183 190
    • (2005) Nat Med , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6
  • 36
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • P. Trayhurn, and I.S. Wood Adipokines: inflammation and the pleiotropic role of white adipose tissue Br J Nutr 92 2004 347 355
    • (2004) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 37
    • 77956335194 scopus 로고    scopus 로고
    • Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action
    • F.T. Wunderlich, P. Strohle, and A.C. Konner Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action Cell Metab 12 2010 237 249
    • (2010) Cell Metab , vol.12 , pp. 237-249
    • Wunderlich, F.T.1    Strohle, P.2    Konner, A.C.3
  • 39
    • 67749142348 scopus 로고    scopus 로고
    • Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes
    • V.T. Samuel, S.A. Beddow, T. Iwasaki, X.M. Zhang, X. Chu, and C.D. Still Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes Proc Natl Acad Sci U S A 106 2009 12121 12126
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12121-12126
    • Samuel, V.T.1    Beddow, S.A.2    Iwasaki, T.3    Zhang, X.M.4    Chu, X.5    Still, C.D.6
  • 40
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
    • S.J. Pilkis, and D.K. Granner Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis Annu Rev Physiol 54 1992 885 909
    • (1992) Annu Rev Physiol , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 41
    • 0037086660 scopus 로고    scopus 로고
    • The glucose-6-phosphatase system
    • E. van Schaftingen, and I. Gerin The glucose-6-phosphatase system Biochem J 362 Pt 3 2002 513 532
    • (2002) Biochem J , vol.362 , Issue.PART 3 , pp. 513-532
    • Van Schaftingen, E.1    Gerin, I.2
  • 42
    • 0031596597 scopus 로고    scopus 로고
    • Interleukin 1beta and interleukin 6, but not tumor necrosis factor alpha, inhibit insulin-stimulated glycogen synthesis in rat hepatocytes
    • T. Kanemaki, H. Kitade, M. Kaibori, K. Sakitani, Y. Hiramatsu, and Y. Kamiyama Interleukin 1beta and interleukin 6, but not tumor necrosis factor alpha, inhibit insulin-stimulated glycogen synthesis in rat hepatocytes Hepatology 27 1998 1296 1303
    • (1998) Hepatology , vol.27 , pp. 1296-1303
    • Kanemaki, T.1    Kitade, H.2    Kaibori, M.3    Sakitani, K.4    Hiramatsu, Y.5    Kamiyama, Y.6
  • 43
    • 0025020079 scopus 로고
    • Interleukin 6 stimulates hepatic glucose release from prelabeled glycogen pools
    • D.G. Ritchie Interleukin 6 stimulates hepatic glucose release from prelabeled glycogen pools Am J Physiol 258 1 Pt 1 1990 E57 E64
    • (1990) Am J Physiol , vol.258 , Issue.1 PART 1
    • Ritchie, D.G.1
  • 44
    • 0033544940 scopus 로고    scopus 로고
    • Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
    • H. Shimano, N. Yahagi, and M. Amemiya-Kudo Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes J Biol Chem 274 1999 35832 35839
    • (1999) J Biol Chem , vol.274 , pp. 35832-35839
    • Shimano, H.1    Yahagi, N.2    Amemiya-Kudo, M.3
  • 45
    • 0033563213 scopus 로고    scopus 로고
    • Structure, function and regulation of pyruvate carboxylase
    • S. Jitrapakdee, and J.C. Wallace Structure, function and regulation of pyruvate carboxylase Biochem J 340 Pt 1 1999 1 16
    • (1999) Biochem J , vol.340 , Issue.PART 1 , pp. 1-16
    • Jitrapakdee, S.1    Wallace, J.C.2
  • 46
    • 0034604248 scopus 로고    scopus 로고
    • Chronic subclinical inflammation as part of the insulin resistance syndrome: The Insulin Resistance Atherosclerosis Study (IRAS)
    • A. Festa, R. D'Agostino Jr., G. Howard, L. Mykkanen, R.P. Tracy, and S.M. Haffner Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS) Circulation 102 2000 42 47
    • (2000) Circulation , vol.102 , pp. 42-47
    • Festa, A.1    D'Agostino, Jr.R.2    Howard, G.3    Mykkanen, L.4    Tracy, R.P.5    Haffner, S.M.6
  • 47
    • 0035344020 scopus 로고    scopus 로고
    • Hepatic mRNAs up-regulated by starvation: An expression profile determined by suppression subtractive hybridization
    • J. Zhang, L.E. Underwood, and A.J. D'Ercole Hepatic mRNAs up-regulated by starvation: an expression profile determined by suppression subtractive hybridization FASEB J 15 2001 1261 1263
    • (2001) FASEB J , vol.15 , pp. 1261-1263
    • Zhang, J.1    Underwood, L.E.2    D'Ercole, A.J.3
  • 48
    • 0032821775 scopus 로고    scopus 로고
    • Weight loss and low body cell mass in males with lung cancer: Relationship with systemic inflammation, acute-phase response, resting energy expenditure, and catabolic and anabolic hormones
    • J.P. Simons, A.M. Schols, W.A. Buurman, and E.F. Wouters Weight loss and low body cell mass in males with lung cancer: relationship with systemic inflammation, acute-phase response, resting energy expenditure, and catabolic and anabolic hormones Clin Sci (Lond) 97 1999 215 223
    • (1999) Clin Sci (Lond) , vol.97 , pp. 215-223
    • Simons, J.P.1    Schols, A.M.2    Buurman, W.A.3    Wouters, E.F.4
  • 49
    • 33845947091 scopus 로고    scopus 로고
    • Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice
    • Y. Tamura, T. Ogihara, and T. Uchida Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice Diabetologia 50 2007 131 141
    • (2007) Diabetologia , vol.50 , pp. 131-141
    • Tamura, Y.1    Ogihara, T.2    Uchida, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.