(+/-)-naringenin as large conductance Ca 2+-activated K + (BK Ca) channel opener in vascular smooth muscle cells

British Journal of Pharmacology

Volumn 149, Issue 8, 2006, Pages 1013-1021

  Saponara, S ^a   Testai, L ^b   Iozzi, D ^a   Martinotti, E ^b   Martelli, A ^b   Chericoni, S ^b   Sgaragli, G ^a   Fusi, F ^a   Calderone, V ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

(+ ) naringenin; Large conductance Ca 2+ activated K + channels; Naringin; Rat aorta ring; Rat tail artery myocyte; Whole cell patch clamp

Indexed keywords

4 AMINOPYRIDINE; AURANTIIN; CALCIUM CHELATING AGENT; CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLIBENCLAMIDE; IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NARINGENIN; NORADRENALIN; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM CHLORIDE; POTASSIUM ION; TETRYLAMMONIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; IC 50; MALE; MUSCLE CELL; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; TAIL ARTERY; VASCULAR RING; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; ARTERIES; CALCIUM; CELL SEPARATION; CHELATING AGENTS; EGTAZIC ACID; ELECTROPHYSIOLOGY; FLAVANONES; KINETICS; MALE; MEMBRANE POTENTIALS; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, SPRAGUE-DAWLEY; VASODILATION;

EID: 33845650271     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706951     Document Type: Article

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