메뉴 건너뛰기




Volumn 35, Issue 10, 2011, Pages 1037-1041

The neurosteroid dehydroepiandrosterone could improve somatic cell reprogramming

Author keywords

Apoptosis; Dehydroepiandrosterone (DHEA); Induced pluripotent stem cells (iPSC); P53; Reprogramming; Stem cell; Steroid

Indexed keywords

PRASTERONE; PROTEIN P53;

EID: 80054983103     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20100927     Document Type: Article
Times cited : (9)

References (77)
  • 1
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005;6:635-45.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 2
    • 77955352428 scopus 로고    scopus 로고
    • Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins
    • Angel M, Yanik MF. Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins. PLoS One 2010;5:e11756.
    • (2010) PLoS One , vol.5
    • Angel, M.1    Yanik, M.F.2
  • 3
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara T, Murohara T, Sullivan A. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997;275:964-67.
    • (1997) Science , vol.275 , pp. 964-967
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3
  • 4
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S, Ramassamy C, Poirier J, Quirion R. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Mol Brain Res 1999;66:35-41.
    • (1999) Mol Brain Res , vol.66 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2    Poirier, J.3    Quirion, R.4
  • 5
    • 80054982417 scopus 로고    scopus 로고
    • Neurosteroids: of the nervous system, by the nervous system, for the nervous system
    • Baulieu EE. Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Psychoneuroendocrinology 1998;2:963-87.
    • (1998) Psychoneuroendocrinology , vol.2 , pp. 963-987
    • Baulieu, E.E.1
  • 6
    • 0033593654 scopus 로고    scopus 로고
    • Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo
    • Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999;283:534-7.
    • (1999) Science , vol.283 , pp. 534-537
    • Bjornson, C.R.1    Rietze, R.L.2    Reynolds, B.A.3    Magli, M.C.4    Vescovi, A.L.5
  • 7
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005;122:947-56.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 8
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain:expression of neuronal phenotypes in adult mice
    • Brazelton TR, Rossi FM, Keshet GI, Blau HM. From marrow to brain:expression of neuronal phenotypes in adult mice. Science 2000;290:1775-9.
    • (2000) Science , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.2    Keshet, G.I.3    Blau, H.M.4
  • 9
    • 48849110380 scopus 로고    scopus 로고
    • Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts
    • Bru T, Clarke C, McGrew MJ, Sang HM, Wilmut I. Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts. Exp Cell Res 2008;15:2634-42.
    • (2008) Exp Cell Res , vol.15 , pp. 2634-2642
    • Bru, T.1    Clarke, C.2    McGrew, M.J.3    Sang, H.M.4    Wilmut, I.5
  • 10
    • 36549033276 scopus 로고    scopus 로고
    • Producing primate embryonic stem cells by somatic cell nuclear transfer
    • Byrne JA, Pedersen DA, Clepper LL, Nelson M, Sanger WG. Producing primate embryonic stem cells by somatic cell nuclear transfer. Nature 2007;450:497-502.
    • (2007) Nature , vol.450 , pp. 497-502
    • Byrne, J.A.1    Pedersen, D.A.2    Clepper, L.L.3    Nelson, M.4    Sanger, W.G.5
  • 11
    • 0034635914 scopus 로고    scopus 로고
    • Effects of p21waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases
    • Chang BD, Watanabe K, Broude EV. Effects of p21waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases. Proc Natl Acad Sci USA 2000;97:4291-6.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4291-4296
    • Chang, B.D.1    Watanabe, K.2    Broude, E.V.3
  • 12
    • 17444388849 scopus 로고    scopus 로고
    • A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents
    • Chang DC, Broudy E, Dokmanovic D. A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents. Cancer Res 1999;59:3761-7.
    • (1999) Cancer Res , vol.59 , pp. 3761-3767
    • Chang, D.C.1    Broudy, E.2    Dokmanovic, D.3
  • 14
    • 0032516063 scopus 로고    scopus 로고
    • Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development
    • Compagnone NA, Mellon SH. Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development. Proc Natl Acad Sci USA 1998;95:4678-83.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4678-4683
    • Compagnone, N.A.1    Mellon, S.H.2
  • 15
    • 23944457397 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
    • Cowan CA, Atienza J, Melton DA, Eggan K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 2005;309:1369-73.
    • (2005) Science , vol.309 , pp. 1369-1373
    • Cowan, C.A.1    Atienza, J.2    Melton, D.A.3    Eggan, K.4
  • 16
    • 31544436888 scopus 로고    scopus 로고
    • Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention?
    • Dashwood RH, Myzak MC, Ho E. Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? Carcinogenesis 2006;27:344-9.
    • (2006) Carcinogenesis , vol.27 , pp. 344-349
    • Dashwood, R.H.1    Myzak, M.C.2    Ho, E.3
  • 17
    • 64349106730 scopus 로고    scopus 로고
    • Targeted bisulfate sequencing reveals changes in DNA methylation associated with nuclear reprogramming
    • Deng J, Shoemaker R, Xie B. Targeted bisulfate sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol 2009;27:353-60.
    • (2009) Nat Biotechnol , vol.27 , pp. 353-360
    • Deng, J.1    Shoemaker, R.2    Xie, B.3
  • 18
    • 33846783210 scopus 로고    scopus 로고
    • Targeting cellular memory to reprogram the epigenome, restore potential, and improve somatic cell nuclear transfer
    • Eilertsen KJ, Power RA, Harkins LL, Misica P. Targeting cellular memory to reprogram the epigenome, restore potential, and improve somatic cell nuclear transfer. Anim Rep Sci 2007;98:129-46.
    • (2007) Anim Rep Sci , vol.98 , pp. 129-146
    • Eilertsen, K.J.1    Power, R.A.2    Harkins, L.L.3    Misica, P.4
  • 19
    • 0038185378 scopus 로고    scopus 로고
    • Genomic targets of the human c-Myc protein
    • Fernandez PC, Frank SR, Wang L. Genomic targets of the human c-Myc protein. Genes Dev 2003;17:1115-29.
    • (2003) Genes Dev , vol.17 , pp. 1115-1129
    • Fernandez, P.C.1    Frank, S.R.2    Wang, L.3
  • 20
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-30.
    • (1998) Science , vol.279 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 21
    • 0035886864 scopus 로고    scopus 로고
    • 2-Difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice
    • Green JE, Shibata MA, Shibata E. 2-Difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice. Cancer Res 2001;61:7449-55.
    • (2001) Cancer Res , vol.61 , pp. 7449-755
    • Green, J.E.1    Shibata, M.A.2    Shibata, E.3
  • 22
    • 0035143154 scopus 로고    scopus 로고
    • Site-specific methylation of the promoter alters deoxyribonucleic acidprotein interactions and prevents folliclestimulating hormone receptor gene transcription
    • Griswold MD, Kim JS. Site-specific methylation of the promoter alters deoxyribonucleic acidprotein interactions and prevents folliclestimulating hormone receptor gene transcription. Biol Reprod 2001;64:602-10.
    • (2001) Biol Reprod , vol.64 , pp. 602-610
    • Griswold, M.D.1    Kim, J.S.2
  • 23
    • 0033598374 scopus 로고    scopus 로고
    • Dystrophin expression in the mdx mouse restored by stem cell transplantation
    • Gussoni E, Soneoka Y, Strickland CD. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 1999;401:390-4.
    • (1999) Nature , vol.401 , pp. 390-394
    • Gussoni, E.1    Soneoka, Y.2    Strickland, C.D.3
  • 24
    • 0033992478 scopus 로고    scopus 로고
    • p53 and human cancer: the first ten thousand mutations
    • Hainaut P, Hollstein M. p53 and human cancer: the first ten thousand mutations. Adv Cancer Res 2000;77:81-137.
    • (2000) Adv Cancer Res , vol.77 , pp. 81-137
    • Hainaut, P.1    Hollstein, M.2
  • 25
    • 47749105737 scopus 로고    scopus 로고
    • Current concepts in reprogramming somatic cells to pluripotent state
    • Han J, Sidhu KS. Current concepts in reprogramming somatic cells to pluripotent state. Curr Stem Cell Res Ther 2008;3:66-74.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 66-74
    • Han, J.1    Sidhu, K.S.2
  • 26
    • 71449109765 scopus 로고    scopus 로고
    • Direct cell reprogramming is a stochastic process amenable to acceleration
    • Hanna J, Saha K, Pando B. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 2009;462:595-601.
    • (2009) Nature , vol.462 , pp. 595-601
    • Hanna, J.1    Saha, K.2    Pando, B.3
  • 27
    • 0036479115 scopus 로고    scopus 로고
    • Transcriptional repression of the antiapoptotic survivin gene by wild-type p53
    • Hoffman WH, Biade S, Zilfou JT, Chen J, Murphy M. Transcriptional repression of the antiapoptotic survivin gene by wild-type p53. J Biol Chem 2002;277:3247-57.
    • (2002) J Biol Chem , vol.277 , pp. 3247-3257
    • Hoffman, W.H.1    Biade, S.2    Zilfou, J.T.3    Chen, J.4    Murphy, M.5
  • 28
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 2009;460:1132-5.
    • (2009) Nature , vol.460 , pp. 1132-1135
    • Hong, H.1    Takahashi, K.2    Ichisaka, T.3    Aoi, T.4    Kanagawa, O.5
  • 29
    • 0026448672 scopus 로고
    • Regulation of the specific DNA binding function of p53
    • Hupp TR, Meek DW, Midgley CA, Lane DP. Regulation of the specific DNA binding function of p53. Cell 1992;71:875-86.
    • (1992) Cell , vol.71 , pp. 875-886
    • Hupp, T.R.1    Meek, D.W.2    Midgley, C.A.3    Lane, D.P.4
  • 30
    • 70350536767 scopus 로고    scopus 로고
    • A small molecule inhibitor of TGF-beta signaling replaces Sox2 in reprogramming by inducing Nanog
    • Ichida J, Blanchard J, Lam K. A small molecule inhibitor of TGF-beta signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 2009;5:491-503.
    • (2009) Cell Stem Cell , vol.5 , pp. 491-503
    • Ichida, J.1    Blanchard, J.2    Lam, K.3
  • 31
    • 77649275936 scopus 로고    scopus 로고
    • A non-viral mini circle vector for deriving human iPS cells
    • Jia F, Wilson KD, Sun N. A non-viral mini circle vector for deriving human iPS cells. Nat Methods 2008;7:197-9.
    • (2008) Nat Methods , vol.7 , pp. 197-199
    • Jia, F.1    Wilson, K.D.2    Sun, N.3
  • 33
    • 0036460078 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression
    • Karishma KK, Herbert J. Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression. Eur J Neurosci 2002;16:445-53.
    • (2002) Eur J Neurosci , vol.16 , pp. 445-453
    • Karishma, K.K.1    Herbert, J.2
  • 34
    • 0028927179 scopus 로고
    • p53, cell cycle control and apoptosis: implications for cancer
    • Kastan MB, Canman CE, Leonard CJ. p53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev 1995;14:3-15.
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 3-15
    • Kastan, M.B.1    Canman, C.E.2    Leonard, C.J.3
  • 35
    • 69349100455 scopus 로고    scopus 로고
    • Linking the p53 tumor suppressor pathway to somatic cell reprogramming
    • Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB. Linking the p53 tumor suppressor pathway to somatic cell reprogramming. Nature 2009;460:1140-4.
    • (2009) Nature , vol.460 , pp. 1140-1144
    • Kawamura, T.1    Suzuki, J.2    Wang, Y.V.3    Menendez, S.4    Morera, L.B.5
  • 36
    • 0025815451 scopus 로고
    • Identification of p53 as a sequencespecific DNA-binding protein
    • Kern SC, Kinzler KW, Bruskin A. Identification of p53 as a sequencespecific DNA-binding protein. Science 1991;252:1708-11.
    • (1991) Science , vol.252 , pp. 1708-1711
    • Kern, S.C.1    Kinzler, K.W.2    Bruskin, A.3
  • 37
    • 70349687407 scopus 로고    scopus 로고
    • Direct reprogramming of human neural stem cells by OCT4
    • Kim JB, Greber B, Arauzo Bravo MJ. Direct reprogramming of human neural stem cells by OCT4. Nature 2009a;461:649-53.
    • (2009) Nature , vol.461 , pp. 649-653
    • Kim, J.B.1    Greber, B.2    Arauzo Bravo, M.J.3
  • 38
    • 59349108302 scopus 로고    scopus 로고
    • Oct4-induced pluripotency in adult neural stem cells
    • Kim JB, Sebastiano V, Wu GM. Oct4-induced pluripotency in adult neural stem cells. Cell 2009b;136:411-9.
    • (2009) Cell , vol.136 , pp. 411-419
    • Kim, J.B.1    Sebastiano, V.2    Wu, G.M.3
  • 39
    • 0035805055 scopus 로고    scopus 로고
    • Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell
    • Krause DS, Theise ND, Collector MI. Multi-organ, multilineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-77.
    • (2001) Cell , vol.105 , pp. 369-377
    • Krause, D.S.1    Theise, N.D.2    Collector, M.I.3
  • 40
    • 0034895297 scopus 로고    scopus 로고
    • DHEA and its transformation into androgens and estrogens in peripheral target tissues:intracrinology
    • Labrie F, Luu-The V, Labrie C, Simard J. DHEA and its transformation into androgens and estrogens in peripheral target tissues:intracrinology. Front Neuroendocrinol 2001;22:185-212.
    • (2001) Front Neuroendocrinol , vol.22 , pp. 185-212
    • Labrie, F.1    Luu-The, V.2    Labrie, C.3    Simard, J.4
  • 41
    • 0033694301 scopus 로고    scopus 로고
    • Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    • Lagasse E, Connors H, Al-Dhalimy M. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-34.
    • (2000) Nat Med , vol.6 , pp. 1229-1234
    • Lagasse, E.1    Connors, H.2    Al-Dhalimy, M.3
  • 42
    • 69349103956 scopus 로고    scopus 로고
    • The Ink4/Arf locus is a barrier for iPS cell reprogramming
    • Li H, Collado M, Villasante A, Strati K, Ortega S. The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 2009;460:1136-9.
    • (2009) Nature , vol.460 , pp. 1136-1139
    • Li, H.1    Collado, M.2    Villasante, A.3    Strati, K.4    Ortega, S.5
  • 43
    • 13944273471 scopus 로고    scopus 로고
    • p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • Lin T, Chao C, Saito S. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 2005;7:165-71.
    • (2005) Nat Cell Biol , vol.7 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3
  • 44
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Gen 2006;38:431-40.
    • (2006) Nat Gen , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3
  • 45
    • 69349094006 scopus 로고    scopus 로고
    • A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
    • Marion RM, Strati K, Li H, Murga M, Blanco R. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 2009;460:1149-53.
    • (2009) Nature , vol.460 , pp. 1149-1153
    • Marion, R.M.1    Strati, K.2    Li, H.3    Murga, M.4    Blanco, R.5
  • 46
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000;290:1779-82.
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3    Maki, R.A.4    McKercher, S.R.5
  • 47
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through integrative genomic analysis
    • Mikkelsen T, Hanna S, Zhang X. Dissecting direct reprogramming through integrative genomic analysis. Nature 2008;454:49-55.
    • (2008) Nature , vol.454 , pp. 49-55
    • Mikkelsen, T.1    Hanna, S.2    Zhang, X.3
  • 48
    • 65949095201 scopus 로고    scopus 로고
    • Cell-free extracts from mammalian oocytes partially induce nuclear reprogramming in somatic cells
    • Miyamoto K, Tsukiyama T, Yang Y, Li N, Minami N. Cell-free extracts from mammalian oocytes partially induce nuclear reprogramming in somatic cells. Biol Rep 2009;80:935-43.
    • (2009) Biol Rep , vol.80 , pp. 935-943
    • Miyamoto, K.1    Tsukiyama, T.2    Yang, Y.3    Li, N.4    Minami, N.5
  • 49
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T, Reed J. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995;80:293-9.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.2
  • 50
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki JI, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Gen 2000;24:372-6.
    • (2000) Nat Gen , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.I.2    Smith, A.G.3
  • 51
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander TF, Weinberg J, Papsdorf M. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 2008;3:97-106.
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3
  • 52
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax that accelerates programmed cell death. Cell 1993;74:609-19.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 53
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-5.
    • (2001) Nature , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 54
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • Petersen BE, Bowen WC, Patrene KD. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-70.
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 55
    • 0033168050 scopus 로고    scopus 로고
    • Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone
    • Rao KV, Johnson WD, Bosland MC. Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone. Cancer Res 1999;59:3084-9.
    • (1999) Cancer Res , vol.59 , pp. 3084-3089
    • Rao, K.V.1    Johnson, W.D.2    Bosland, M.C.3
  • 56
    • 0035839106 scopus 로고    scopus 로고
    • Nuclear cloning and epigenetic reprogramming of the genome
    • Rideout WM, Eggan K, Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science 2001;293:1093-8.
    • (2001) Science , vol.293 , pp. 1093-1098
    • Rideout, W.M.1    Eggan, K.2    Jaenisch, R.3
  • 57
    • 0025269544 scopus 로고
    • Mechanisms of chemoprevention by dietary dehydroisoandrosterone. Inhibition of lymphopoiesis
    • Risdon G, Cope J, Bennett M. Mechanisms of chemoprevention by dietary dehydroisoandrosterone. Inhibition of lymphopoiesis. Am J Pathol 1990;136:759-69.
    • (1990) Am J Pathol , vol.136 , pp. 759-769
    • Risdon, G.1    Cope, J.2    Bennett, M.3
  • 58
    • 0026083240 scopus 로고
    • Differential effects of dehydroepiandrosterone (DHEA) on murine lymphopoiesis and myelopoiesis
    • Risdon G, Kumar V, Bennett M. Differential effects of dehydroepiandrosterone (DHEA) on murine lymphopoiesis and myelopoiesis. Exp Hematol 1991;19:128-31.
    • (1991) Exp Hematol , vol.19 , pp. 128-131
    • Risdon, G.1    Kumar, V.2    Bennett, M.3
  • 59
    • 30144440248 scopus 로고    scopus 로고
    • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
    • Rowland BD, Bernards R, Peeper DS. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat Cell Biol 2005;7:1074-82.
    • (2005) Nat Cell Biol , vol.7 , pp. 1074-1082
    • Rowland, B.D.1    Bernards, R.2    Peeper, D.S.3
  • 60
    • 0029549898 scopus 로고
    • Mechanism of cancer prevention action of DHEA
    • Schwartz A, Pashko L. Mechanism of cancer prevention action of DHEA. Ann NY Acad Sci 1995;774:180-6.
    • (1995) Ann NY Acad Sci , vol.774 , pp. 180-186
    • Schwartz, A.1    Pashko, L.2
  • 62
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F, Hockemeyer D, Beard C. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009;136:964-77.
    • (2009) Cell , vol.136 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3
  • 63
    • 77952425747 scopus 로고    scopus 로고
    • Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
    • Stadtfeld M, Utikal J, Weir G. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 2010;465:175-81.
    • (2010) Nature , vol.465 , pp. 175-181
    • Stadtfeld, M.1    Utikal, J.2    Weir, G.3
  • 64
    • 0030886015 scopus 로고    scopus 로고
    • Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53
    • Sugrue MM, Shin DY, Lee SW, Aaronson SA. Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Proc Natl Acad Sci USA 1997;94:9648-53.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9648-9653
    • Sugrue, M.M.1    Shin, D.Y.2    Lee, S.W.3    Aaronson, S.A.4
  • 65
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 66
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-72.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5
  • 67
    • 34250854663 scopus 로고    scopus 로고
    • Neuroepithelial cells supply an initial transient wave of MSC differentiation
    • Takashima Y, Era T, Nakao K. Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell 2007;129:1377-88.
    • (2007) Cell , vol.129 , pp. 1377-1388
    • Takashima, Y.1    Era, T.2    Nakao, K.3
  • 68
    • 28644443829 scopus 로고    scopus 로고
    • Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells
    • Taranger CK, Noer A, Sørensen AL, Hakelien AM, Boquest AC. Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Mol Biol Cell 2005;16:5719-5735.
    • (2005) Mol Biol Cell , vol.16 , pp. 5719-5735
    • Taranger, C.K.1    Noer, A.2    Sørensen, A.L.3    Hakelien, A.M.4    Boquest, A.C.5
  • 69
    • 69349098273 scopus 로고    scopus 로고
    • Immortalization eliminates a road block during cellular reprogramming into iPS cells
    • Utikal J, Polo JM, Stadtfeld M. Immortalization eliminates a road block during cellular reprogramming into iPS cells. Nature 2009;460:1145-8.
    • (2009) Nature , vol.460 , pp. 1145-1148
    • Utikal, J.1    Polo, J.M.2    Stadtfeld, M.3
  • 70
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: the cell's response p53
    • Vousden KH, Lu X. Live or let die: the cell's response p53. Nat Rev Cancer 2002;2:594-604.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 71
    • 49449096588 scopus 로고    scopus 로고
    • A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
    • Wernig M, Lengner CJ, Hanna J. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat Biotech 2008;26:916-24.
    • (2008) Nat Biotech , vol.26 , pp. 916-924
    • Wernig, M.1    Lengner, C.J.2    Hanna, J.3
  • 73
    • 9844232032 scopus 로고    scopus 로고
    • Re-expression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition
    • Xu HJ, Zhou Y, Ji W. Re-expression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition. Oncogene 1997;15:2589-96.
    • (1997) Oncogene , vol.15 , pp. 2589-2596
    • Xu, H.J.1    Zhou, Y.2    Ji, W.3
  • 74
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917-20.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 75
    • 24344499512 scopus 로고    scopus 로고
    • Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription
    • Zhang Y, Fatima N, Dufau ML. Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription. Mol Cell Biol 2005;25:7929-39.
    • (2005) Mol Cell Biol , vol.25 , pp. 7929-7939
    • Zhang, Y.1    Fatima, N.2    Dufau, M.L.3
  • 76
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4:381-4.
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 77
    • 77952779185 scopus 로고    scopus 로고
    • Demethylation of LHR in Dehydroepiandrosterone induced mouse model of polycystic ovary syndrome
    • Zhu JQ, Zhu L, Liang XW. Demethylation of LHR in Dehydroepiandrosterone induced mouse model of polycystic ovary syndrome. Mol Hum Reprod 2010;16:260-6.
    • (2010) Mol Hum Reprod , vol.16 , pp. 260-266
    • Zhu, J.Q.1    Zhu, L.2    Liang, X.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.