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Volumn 38, Issue 10, 2011, Pages 497-504

Chemical genetics and drug screening in Drosophila cancer models

Author keywords

Cancer; Drosophila; Drug screening

Indexed keywords

APC PROTEIN; JANUS KINASE; PROTEIN RET; STAT PROTEIN; WNT PROTEIN;

EID: 80054960898     PISSN: 16738527     EISSN: 18735533     Source Type: Journal    
DOI: 10.1016/j.jgg.2011.09.003     Document Type: Review
Times cited : (50)

References (62)
  • 1
    • 33746826011 scopus 로고    scopus 로고
    • JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions
    • Arbouzova N.I., Zeidler M.P. JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions. Development 2006, 133:2605-2616.
    • (2006) Development , vol.133 , pp. 2605-2616
    • Arbouzova, N.I.1    Zeidler, M.P.2
  • 2
    • 33751530490 scopus 로고    scopus 로고
    • Mining the Wnt pathway for cancer therapeutics
    • Barker N., Clevers H. Mining the Wnt pathway for cancer therapeutics. Nat. Rev. Drug Discov. 2006, 5:997-1014.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 997-1014
    • Barker, N.1    Clevers, H.2
  • 3
    • 77649176432 scopus 로고    scopus 로고
    • Imaginal discs: renaissance of a model for regenerative biology
    • Bergantinos C., Vilana X., Corominas M., Serras F. Imaginal discs: renaissance of a model for regenerative biology. Bioessays 2010, 32:207-217.
    • (2010) Bioessays , vol.32 , pp. 207-217
    • Bergantinos, C.1    Vilana, X.2    Corominas, M.3    Serras, F.4
  • 4
    • 0035909523 scopus 로고    scopus 로고
    • Studies on human colon cancer gene APC by targeted expression in Drosophila
    • Bhandari P., Shashidhara L.S. Studies on human colon cancer gene APC by targeted expression in Drosophila. Oncogene 2001, 20:6871-6880.
    • (2001) Oncogene , vol.20 , pp. 6871-6880
    • Bhandari, P.1    Shashidhara, L.S.2
  • 5
    • 0242641565 scopus 로고    scopus 로고
    • Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
    • Brumby A.M., Richardson H.E. scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J. 2003, 22:5769-5779.
    • (2003) EMBO J. , vol.22 , pp. 5769-5779
    • Brumby, A.M.1    Richardson, H.E.2
  • 6
    • 23144434969 scopus 로고    scopus 로고
    • Using Drosophila melanogaster to map human cancer pathways
    • Brumby A.M., Richardson H.E. Using Drosophila melanogaster to map human cancer pathways. Nat. Rev. Cancer 2005, 5:626-639.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 626-639
    • Brumby, A.M.1    Richardson, H.E.2
  • 8
    • 27144555447 scopus 로고    scopus 로고
    • Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
    • Caussinus E., Gonzalez C. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat. Genet. 2005, 37:1125-1129.
    • (2005) Nat. Genet. , vol.37 , pp. 1125-1129
    • Caussinus, E.1    Gonzalez, C.2
  • 9
    • 18944388680 scopus 로고    scopus 로고
    • Mouse axin and axin2/conductin proteins are functionally equivalent in vivo
    • Chia I.V., Costantini F. Mouse axin and axin2/conductin proteins are functionally equivalent in vivo. Mol. Cell. Biol. 2005, 25:4371-4376.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4371-4376
    • Chia, I.V.1    Costantini, F.2
  • 10
    • 0001085592 scopus 로고
    • Imaginal disc development
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, M. Bate, A.M. Arias (Eds.)
    • Cohen S. Imaginal disc development. The Development of Drosophila melanogaster 1993, 747-841. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. M. Bate, A.M. Arias (Eds.).
    • (1993) The Development of Drosophila melanogaster , pp. 747-841
    • Cohen, S.1
  • 11
    • 78349235095 scopus 로고    scopus 로고
    • Drosophila as a novel therapeutic discovery tool for thyroid cancer
    • Das T., Cagan R. Drosophila as a novel therapeutic discovery tool for thyroid cancer. Thyroid 2010, 20:689-695.
    • (2010) Thyroid , vol.20 , pp. 689-695
    • Das, T.1    Cagan, R.2
  • 12
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • DeGregori J., Johnson D.G. Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr. Mol. Med. 2006, 6:739-748.
    • (2006) Curr. Mol. Med. , vol.6 , pp. 739-748
    • DeGregori, J.1    Johnson, D.G.2
  • 13
    • 53649108148 scopus 로고    scopus 로고
    • Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling
    • Dow L.E., Elsum I.A., King C.L., Kinross K.M., Richardson H.E., Humbert P.O. Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling. Oncogene 2008, 27:5988-6001.
    • (2008) Oncogene , vol.27 , pp. 5988-6001
    • Dow, L.E.1    Elsum, I.A.2    King, C.L.3    Kinross, K.M.4    Richardson, H.E.5    Humbert, P.O.6
  • 14
    • 0022884576 scopus 로고
    • Repression and turnover pattern fushi tarazu RNA in the early Drosophila embryo
    • Edgar B.A., Weir M.P., Schubiger G., Kornberg T. Repression and turnover pattern fushi tarazu RNA in the early Drosophila embryo. Cell 1986, 47:747-754.
    • (1986) Cell , vol.47 , pp. 747-754
    • Edgar, B.A.1    Weir, M.P.2    Schubiger, G.3    Kornberg, T.4
  • 15
    • 79959678739 scopus 로고    scopus 로고
    • Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells
    • Edwards A., Gladstone M., Yoon P., Raben D., Frederick B., Su T.T. Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells. Dis. Model Mech. 2011, 4:496-503.
    • (2011) Dis. Model Mech. , vol.4 , pp. 496-503
    • Edwards, A.1    Gladstone, M.2    Yoon, P.3    Raben, D.4    Frederick, B.5    Su, T.T.6
  • 16
    • 52949102178 scopus 로고    scopus 로고
    • Apoptosis-induced compensatory proliferation. The cell is dead. Long live the cell!
    • Fan Y., Bergmann A. Apoptosis-induced compensatory proliferation. The cell is dead. Long live the cell!. Trends Cell Biol. 2008, 18:467-473.
    • (2008) Trends Cell Biol. , vol.18 , pp. 467-473
    • Fan, Y.1    Bergmann, A.2
  • 17
    • 42049095950 scopus 로고    scopus 로고
    • Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye
    • Fan Y., Bergmann A. Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye. Dev Cell. 2008, 14:399-410.
    • (2008) Dev Cell. , vol.14 , pp. 399-410
    • Fan, Y.1    Bergmann, A.2
  • 18
    • 0034704752 scopus 로고    scopus 로고
    • A Drosophila model of Parkinson's disease
    • Feany M.B., Bender W.W. A Drosophila model of Parkinson's disease. Nature 2000, 404:394-398.
    • (2000) Nature , vol.404 , pp. 394-398
    • Feany, M.B.1    Bender, W.W.2
  • 20
    • 80054726336 scopus 로고    scopus 로고
    • A screen for radiation sensitizers of Drosophila checkpoint mutants
    • Humana Press, 782, 105-117, W. Li (Ed.)
    • Gladstone M., Su T.T. A screen for radiation sensitizers of Drosophila checkpoint mutants. Cell Cycle Checkpoints: Methods and Protocols 2011, Humana Press, 782, 105-117. W. Li (Ed.).
    • (2011) Cell Cycle Checkpoints: Methods and Protocols
    • Gladstone, M.1    Su, T.T.2
  • 22
    • 17444423289 scopus 로고    scopus 로고
    • Wnt signaling in the intestinal epithelium: from endoderm to cancer
    • Gregorieff A., Clevers H. Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev. 2005, 19:877-890.
    • (2005) Genes Dev. , vol.19 , pp. 877-890
    • Gregorieff, A.1    Clevers, H.2
  • 23
    • 33845478597 scopus 로고    scopus 로고
    • Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila
    • Hariharan I.K., Bilder D. Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila. Annu. Rev. Genet. 2006, 40:335-361.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 335-361
    • Hariharan, I.K.1    Bilder, D.2
  • 25
    • 79952650312 scopus 로고    scopus 로고
    • The Ly6 protein coiled is required for septate junction and blood brain barrier organisation in Drosophila
    • Hijazi A., Haenlin M., Waltzer L., Roch F. The Ly6 protein coiled is required for septate junction and blood brain barrier organisation in Drosophila. PLoS ONE 2011, 6:e17763.
    • (2011) PLoS ONE , vol.6
    • Hijazi, A.1    Haenlin, M.2    Waltzer, L.3    Roch, F.4
  • 26
    • 10044297023 scopus 로고    scopus 로고
    • Exposing Drosophila to neuroactive drugs
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, W. Sullivan, M. Ashburner, R.S. Hawley (Eds.)
    • Hirsh J. Exposing Drosophila to neuroactive drugs. Drosophila Protocols 2000, 617-623. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. W. Sullivan, M. Ashburner, R.S. Hawley (Eds.).
    • (2000) Drosophila Protocols , pp. 617-623
    • Hirsh, J.1
  • 28
    • 0032168160 scopus 로고    scopus 로고
    • Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
    • Jackson G.R., Salecker I., Dong X., Yao X., Arnheim N., Faber P.W., MacDonald M.E., Zipursky S.L. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron 1998, 21:633-642.
    • (1998) Neuron , vol.21 , pp. 633-642
    • Jackson, G.R.1    Salecker, I.2    Dong, X.3    Yao, X.4    Arnheim, N.5    Faber, P.W.6    MacDonald, M.E.7    Zipursky, S.L.8
  • 29
    • 0037118247 scopus 로고    scopus 로고
    • Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
    • Jackson G.R., Wiedau-Pazos M., Sang T.K., Wagle N., Brown C.A., Massachi S., Geschwind D.H. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 2002, 34:509-519.
    • (2002) Neuron , vol.34 , pp. 509-519
    • Jackson, G.R.1    Wiedau-Pazos, M.2    Sang, T.K.3    Wagle, N.4    Brown, C.A.5    Massachi, S.6    Geschwind, D.H.7
  • 31
    • 56749171402 scopus 로고    scopus 로고
    • Drosophila asymmetric division, polarity and cancer
    • Januschke J., Gonzalez C. Drosophila asymmetric division, polarity and cancer. Oncogene 2008, 27:6994-7002.
    • (2008) Oncogene , vol.27 , pp. 6994-7002
    • Januschke, J.1    Gonzalez, C.2
  • 32
    • 64549110803 scopus 로고    scopus 로고
    • EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors
    • Jiang H., Edgar B.A. EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 2009, 136:483-493.
    • (2009) Development , vol.136 , pp. 483-493
    • Jiang, H.1    Edgar, B.A.2
  • 33
    • 0028361914 scopus 로고
    • Analog of vertebrate anionic sites in blood-brain interface of larval Drosophila
    • Juang J.L., Carlson S.D. Analog of vertebrate anionic sites in blood-brain interface of larval Drosophila. Cell Tissue Res. 1994, 277:87-95.
    • (1994) Cell Tissue Res. , vol.277 , pp. 87-95
    • Juang, J.L.1    Carlson, S.D.2
  • 34
    • 21744436611 scopus 로고    scopus 로고
    • Rod-Zw10-Zwilch: a key player in the spindle checkpoint
    • Karess R. Rod-Zw10-Zwilch: a key player in the spindle checkpoint. Trends Cell Biol. 2005, 15:386-392.
    • (2005) Trends Cell Biol. , vol.15 , pp. 386-392
    • Karess, R.1
  • 36
    • 70450198995 scopus 로고    scopus 로고
    • Cell competition, growth and size control in the Drosophila wing imaginal disc
    • Martin F.A., Herrera S.C., Morata G. Cell competition, growth and size control in the Drosophila wing imaginal disc. Development 2009, 136:3747-3756.
    • (2009) Development , vol.136 , pp. 3747-3756
    • Martin, F.A.1    Herrera, S.C.2    Morata, G.3
  • 37
    • 69549105422 scopus 로고    scopus 로고
    • Apoptosis in Drosophila: compensatory proliferation and undead cells
    • Martin F.A., Perez-Garijo A., Morata G. Apoptosis in Drosophila: compensatory proliferation and undead cells. Int. J. Dev. Biol. 2009, 53:1341-1347.
    • (2009) Int. J. Dev. Biol. , vol.53 , pp. 1341-1347
    • Martin, F.A.1    Perez-Garijo, A.2    Morata, G.3
  • 38
    • 31444452338 scopus 로고    scopus 로고
    • Evidence that stem cells reside in the adult Drosophila midgut epithelium
    • Micchelli C.A., Perrimon N. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature 2006, 439:475-479.
    • (2006) Nature , vol.439 , pp. 475-479
    • Micchelli, C.A.1    Perrimon, N.2
  • 39
    • 78649731667 scopus 로고    scopus 로고
    • Driving chromosome segregation: lessons from the human and Drosophila centromere-kinetochore machinery
    • Orr B., Afonso O., Feijao T., Sunkel C.E. Driving chromosome segregation: lessons from the human and Drosophila centromere-kinetochore machinery. Biochem. Soc. Trans. 2010, 38:1667-1675.
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 1667-1675
    • Orr, B.1    Afonso, O.2    Feijao, T.3    Sunkel, C.E.4
  • 40
    • 0242666126 scopus 로고    scopus 로고
    • A genetic screen in Drosophila for metastatic behavior
    • Pagliarini R.A., Xu T. A genetic screen in Drosophila for metastatic behavior. Science 2003, 302:1227-1231.
    • (2003) Science , vol.302 , pp. 1227-1231
    • Pagliarini, R.A.1    Xu, T.2
  • 41
    • 0442323560 scopus 로고    scopus 로고
    • Tuberous sclerosis complex: from Drosophila to human disease
    • Pan D., Dong J., Zhang Y., Gao X. Tuberous sclerosis complex: from Drosophila to human disease. Trends Cell Biol. 2004, 14:78-85.
    • (2004) Trends Cell Biol. , vol.14 , pp. 78-85
    • Pan, D.1    Dong, J.2    Zhang, Y.3    Gao, X.4
  • 42
    • 79955749505 scopus 로고    scopus 로고
    • Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery
    • Pandey U.B., Nichols C.D. Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacol. Rev. 2011, 63:411-436.
    • (2011) Pharmacol. Rev. , vol.63 , pp. 411-436
    • Pandey, U.B.1    Nichols, C.D.2
  • 43
    • 0025053965 scopus 로고
    • The ultrastructure of imaginal disc cells in primary cultures and during cell aggregation in continuous cell lines
    • Peel D.J., Johnson S.A., Milner M.J. The ultrastructure of imaginal disc cells in primary cultures and during cell aggregation in continuous cell lines. Tissue Cell 1990, 22:749-758.
    • (1990) Tissue Cell , vol.22 , pp. 749-758
    • Peel, D.J.1    Johnson, S.A.2    Milner, M.J.3
  • 44
    • 33846193290 scopus 로고    scopus 로고
    • The many ways of Wnt in cancer
    • Polakis P. The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 2007, 17:45-51.
    • (2007) Curr. Opin. Genet. Dev. , vol.17 , pp. 45-51
    • Polakis, P.1
  • 45
    • 0037108151 scopus 로고    scopus 로고
    • Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
    • Radimerski T., Montagne J., Hemmings-Mieszczak M., Thomas G. Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Genes Dev. 2002, 16:2627-2632.
    • (2002) Genes Dev. , vol.16 , pp. 2627-2632
    • Radimerski, T.1    Montagne, J.2    Hemmings-Mieszczak, M.3    Thomas, G.4
  • 48
    • 30744450262 scopus 로고    scopus 로고
    • Transport of polyamines in Drosophila S2 cells: kinetics, pharmacology and dependence on the plasma membrane proton gradient
    • Romero-Calderon R., Krantz D.E. Transport of polyamines in Drosophila S2 cells: kinetics, pharmacology and dependence on the plasma membrane proton gradient. Biochem. J. 2006, 393:583-589.
    • (2006) Biochem. J. , vol.393 , pp. 583-589
    • Romero-Calderon, R.1    Krantz, D.E.2
  • 51
    • 78649634635 scopus 로고    scopus 로고
    • Distinct death mechanisms in Drosophila development
    • Ryoo H.D., Baehrecke E.H. Distinct death mechanisms in Drosophila development. Curr. Opin. Cell Biol. 2010, 22:889-895.
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 889-895
    • Ryoo, H.D.1    Baehrecke, E.H.2
  • 52
    • 5044248528 scopus 로고    scopus 로고
    • Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways
    • Ryoo H.D., Gorenc T., Steller H. Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. Dev. Cell 2004, 7:491-501.
    • (2004) Dev. Cell , vol.7 , pp. 491-501
    • Ryoo, H.D.1    Gorenc, T.2    Steller, H.3
  • 53
    • 0002726419 scopus 로고    scopus 로고
    • BrdU labeling of chromosomes
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, W. Sullivan, M. Ashburner, R.S. Hawley (Eds.)
    • Shermoen A. BrdU labeling of chromosomes. Drosophila Protocols 2000, 57-65. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. W. Sullivan, M. Ashburner, R.S. Hawley (Eds.).
    • (2000) Drosophila Protocols , pp. 57-65
    • Shermoen, A.1
  • 54
    • 33845627082 scopus 로고    scopus 로고
    • Cellular responses to DNA damage: one signal, multiple choices
    • Su T.T. Cellular responses to DNA damage: one signal, multiple choices. Annu. Rev. Genet. 2006, 40:187-208.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 187-208
    • Su, T.T.1
  • 55
    • 38349111992 scopus 로고    scopus 로고
    • A Drosophila model to identify polyamine-drug conjugates that target the polyamine transporter in an intact epithelium
    • Tsen C., Iltis M., Kaur N., Bayer C., Delcros J.G., von Kalm L., Phanstiel O.T. A Drosophila model to identify polyamine-drug conjugates that target the polyamine transporter in an intact epithelium. J. Med. Chem. 2008, 51:324-330.
    • (2008) J. Med. Chem. , vol.51 , pp. 324-330
    • Tsen, C.1    Iltis, M.2    Kaur, N.3    Bayer, C.4    Delcros, J.G.5    von Kalm, L.6    Phanstiel, O.T.7
  • 56
    • 30644469503 scopus 로고    scopus 로고
    • Drosophila models for cancer research
    • Vidal M., Cagan R.L. Drosophila models for cancer research. Curr. Opin. Genet. Dev. 2006, 16:10-16.
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 10-16
    • Vidal, M.1    Cagan, R.L.2
  • 57
    • 18144392678 scopus 로고    scopus 로고
    • ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma
    • Vidal M., Wells S., Ryan A., Cagan R. ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res. 2005, 65:3538-3541.
    • (2005) Cancer Res. , vol.65 , pp. 3538-3541
    • Vidal, M.1    Wells, S.2    Ryan, A.3    Cagan, R.4
  • 58
    • 75749106942 scopus 로고    scopus 로고
    • Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion
    • Wu M., Pastor-Pareja J.C., Xu T. Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature 2010, 463:545-548.
    • (2010) Nature , vol.463 , pp. 545-548
    • Wu, M.1    Pastor-Pareja, J.C.2    Xu, T.3
  • 59
    • 0033581953 scopus 로고    scopus 로고
    • Ectopic expression of human p53 inhibits entry into S phase and induces apoptosis in the Drosophila eye imaginal disc
    • Yamaguchi M., Hirose F., Inoue Y.H., Shiraki M., Hayashi Y., Nishi Y., Matsukage A. Ectopic expression of human p53 inhibits entry into S phase and induces apoptosis in the Drosophila eye imaginal disc. Oncogene 1999, 18:6767-6775.
    • (1999) Oncogene , vol.18 , pp. 6767-6775
    • Yamaguchi, M.1    Hirose, F.2    Inoue, Y.H.3    Shiraki, M.4    Hayashi, Y.5    Nishi, Y.6    Matsukage, A.7
  • 60
    • 0029069540 scopus 로고
    • Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
    • Yu C.L., Meyer D.J., Campbell G.S., Larner A.C., Carter-Su C., Schwartz J., Jove R. Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 1995, 269:81-83.
    • (1995) Science , vol.269 , pp. 81-83
    • Yu, C.L.1    Meyer, D.J.2    Campbell, G.S.3    Larner, A.C.4    Carter-Su, C.5    Schwartz, J.6    Jove, R.7
  • 61
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer-new molecular targets come of age
    • Yu H., Jove R. The STATs of cancer-new molecular targets come of age. Nat. Rev. Cancer 2004, 4:97-105.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 62
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: a leading role for STAT3
    • Yu H., Pardoll D., Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat. Rev. Cancer 2009, 9:798-809.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3


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