Prolonged membrane depolarization enhances midbrain dopamine neuron differentiation via epigenetic histone modifications

Stem Cells

Volumn 29, Issue 11, 2011, Pages 1861-1873

  He, Xi Biao ^a   Yi, Sang Hoon ^a   Rhee, Yong Hee ^a   Kim, Hyemin ^b   Han, Yong Mahn ^b   Lee, Suk Ho ^c   Lee, Hyunsu ^c   Park, Chang Hwan ^a   Lee, Yong Sung ^a   Richardson, Eric ^a   Kim, Byung Woo ^a,d   Lee, Sang Hun ^a  

^a Hanyang University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d Chungju National University   (South Korea)

Author keywords

Depolarization; Dopaminergic neuron; Histone modifications; MeCP2; Neural stem cell; Nurr1

Indexed keywords

CALCIUM; DOPAMINE TRANSPORTER; HISTONE H3; METHYL CPG BINDING PROTEIN 2; NUCLEAR RECEPTOR RELATED FACTOR 1; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL STIMULATION; CHROMATIN; CONTROLLED STUDY; CPG ISLAND; DISSOCIATION; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYONIC STEM CELL; EPIGENETICS; HISTONE ACETYLATION; HISTONE MODIFICATION; MESENCEPHALON; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NEURAL STEM CELL; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; RAT;

ANIMALS; CALCIUM; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DNA METHYLATION; DOPAMINERGIC NEURONS; EPIGENESIS, GENETIC; HISTONES; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; METHYL-CPG-BINDING PROTEIN 2; NEURAL STEM CELLS; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 2; RATS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 80054951619     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.739     Document Type: Article

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