Ascorbate-induced differentiation of embryonic cortical precursors into neurons and astrocytes

Journal of Neuroscience Research

Volumn 73, Issue 2, 2003, Pages 156-165

  Lee, Ji Yeon ^a   Chang, Mi Yoon ^a   Park, Chang Hwan ^a   Kim, Hye Young ^a   Kim, Jin Hyuk ^a   Son, Hyeon ^a   Lee, Yong Sung ^a   Lee, Sang Hun ^a  

^a Hanyang University   (South Korea)

Author keywords

Ascorbate; CNS development; CNS precursors; Differentiation; Synaptic maturation

Indexed keywords

ASCORBIC ACID;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN DEVELOPMENT; CELL DENSITY; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; GENE EXPRESSION; GLIA CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; STEM CELL; SYNAPSE;

ANIMALS; ASCORBIC ACID; ASTROCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CEREBRAL CORTEX; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; NEURONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0038167080     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10647     Document Type: Article

References (50)

1. Agus DB, Gambhir SS, Pardridge WM, Spielholz C, Baselga J, Vera JC, Golde DW. 1997. Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. J Clin Invest 100:2842-2848.
2. Brahma B, Forman RE, Stewart EE, Nicholson C, Rice ME. 2000. Ascorbate inhibits edema in brain slices. J Neurochem 74:1263-1270.
3. Brewer GJ, Torricelli JR, Evege EK, Price PJ. 1993. Optimized survival of hippocampal neurons in B27-supplementated Neurobasal, a new serum-free medium combination. J Neurosci Res 35:567-576.
4. Cao W, Carney JM, Duchon A, Floyd RA, Chevion M. 1988. Oxygen free radical involvement in ischemia and reperfusion injury to brain. Neurosci Lett 88:233-238.
5. Chang M-Y, Son H, Lee Y-S, Lee SH. 2003. Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively. Mol Cell Neurosci (in press).
6. Diliberto EJ Jr, Menniti FS, Knoth J, Daniels AJ, Kizer JS, Viveros OH. 1987. Adrenomedullary chromaffin cells as a model to study the neurobiology of ascorbic acid: from monooxygenation to neuromodulation. Ann N Y Acad Sci 498:28-53.
7. Gross RE, Mehler MF, Mabie PC, Zang ZY, Santschi L, Kessler JA. 1996. Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron 17:595-606.
8. Grunewald RA. 1993. Ascorbic acid in the brain. Brain Res Rev 18:123-133.
9. Ha HC, Thiagalingam A, Nelkin BD, Casero RA Jr. 2000. Reactive oxygen species are critical for the growth and differentiation of medullary thyroid carcinoma cells. Clin Cancer Res 6:3783-3787.
10. Halliwell B. 1996. Vitamin C: antioxidant and pro-oxidant in vivo. Free Radic Res 25:439-454.
11. Halliwell B, Foyer CH. 1976. Ascorbic acid, metal ions and the superoxide radical. Biochem J 155:697-700.
12. 3H]spiroperidol binding in neostriatal membrane preparations. J Neurochem 41:1384-1392.
13. Henry PT, Chandry MJ. 1998. Effect of ascorbic acid on infarct size in experimental focal cerebral ischemia and reperfusion in a primate model. Acta Neurochir 140:977-980.
14. Johe KK, Hazel TG, Muller T, Dugich-Djordjevic MM, McKay RD. 1996. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev 10:3129-3140.
15. Kalir H, Mytilineou C. 1991. Ascorbic acid in mesencephalic cultures: Effects on dopaminergic neuron development. J Neurochem 57:458-464.
16. Kratzing CC, Kelly JD, Kratzing JE. 1985. Ascorbic acid in fetal rat brain. J Neurochem 44:1623-1624.
17. Kuo CH, Yonehara N, Hata F, Yoshida H. 1978. Subcellular distribution of ascorbic acid in rat brain. Jpn J Pharmacol 28:789-791.
18. Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H. 1995. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268:836-844.
19. López-Coviella I, Berse B, Krauss R, Thies RS, Blusztajn JK. 2000. Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9. Science 289:313-316.
20. Makar TK, Nedergaard M, Preuss A, Gelbard AS, Perumal AS, Cooper AJL. 1994. Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of oxidative metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. J Neurochem 62:45-53.
21. Milby K, Oke A, Adams PN. 1982. Detailed mapping of ascorbate distribution in rat brain. Neurosci Lett 28:15-20.
22. Miele M, Fillenz M. 1996. In vivo determination of extracellular brain ascorbate. J Neurosci Methods 70:15-19.
23. Morrison SJ, Perez SE, Qiao Z, Verdi JM, Hicks C, Weinmaster G, Anderson DJ. 2000. Transient notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell 101:499-510.
24. Otsuka E, Yamaguchi A, Hirose S, Hagiwara H. 1999. Characterization of osteoblastic differentiation of stromal cell line ST2 that is induced by ascorbic acid. Am J Physiol 277:C132-C138.
25. Peluso JJ. 2000. N-cadherin-mediated cell contact regulates ovarian surface epithelial cell survival. Biol Signals Recept 9:115-121.
26. Pérez-Pinzón MA, Patricia LM, Myron R, Thomas JS. 1997. Antioxidants, mitochondrial hyperoxidation and electrical recovery after anoxia in hippocampal slices. Brain Res 754:163-170.
27. Pilling D, Akbar AN, Shamsadeen N, Scheel-Toellner D, Buckley C, Salmon M. 2000. High cell density provides potent survival signals for resting T-cells. Cell Mol Biol 46:163-174.
28. Ranjan A, Theodore D, Haran RP, Chandy MJ. 1993. Ascorbic acid and focal ischemia in a primate model. Acta Neurochir 123:87-91.
29. Rebec GV, Pierce RC. 1994. A vitamin as neuromodulator: ascorbate release into the extracellular fluid of the brain regulates dopaminergic and glutamergic transmission. Prog Neurobiol 43:537-565.
30. Rice ME. 2000. Ascorbate regulation and its neuroprotective role in the brain. Trends Neurosci 23:209-216.
31. Rice ME, Pérez-Pinzón MA, Lee EJK. 1994. Ascorbic acid, but not glutathione, is taken up by brain slices and preserves cell morphology. J Neurophysiol 71:1591-1596.
32. Rice ME, Lee EM, Choy Y. 1995. High levels of ascorbic acid, not glutathione, in the CNS of anoxia-tolerant reptiles contrasted with levels in anoxia-intolerant species. J Neurochem 64:1790-1799.
33. Ronchetti IP, Quaglino D Jr, Bergamini G. 1996. Ascorbic acid and connective tissue. In: Subcellular biochemistry: ascorbic acid: biochemistry and biomedical cell biology. New York: Plenum.
34. Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M. 1997. Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. J Biol Chem 272:18982-18989.
35. Sauer H, Wartenberg M, Hescheler J. 2001. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 11:173-186.
36. Schenk JO, Miller E, Gaddis R, Adams RN. 1982. Homeostatic control of ascorbic acid concentration in CNS extracellular fluid. Brain Res 253:353-356.
37. Sciamanna MA, Lee CP. 1993. Ischemia/reperfusion-induced injury of forebrain mitochondria and protection by ascorbate. Arch Biochem Biophys 305:215-224.
38. Si F, Ross GM, Shin SH. 1998. Glutathione protects PC12 cells from ascorbate- and dopamine-induced apoptosis. Exp Brain Res 123:263-268.
39. Siushnsian R, Wilson JX. 1995. Ascorbate transport and intracellular concentration in cerebral astrocytes. J Neurochem 66:1227-1233.
40. Song JH, Shin SH, Ross GM. 1999. Prooxidant effects of ascorbate in rat brain slice. J Neurosci Res 58:328-336.
41. Song JH, Shin SH, Ross GM. 2001. Oxidative stress induced by ascorbate causes neuronal damage in an in vitro system. Brain Res 895:66-72.
42. Stamford JA, Kruk ZL, Millar J. 1984. Regional differences in extracellular ascorbic acid levels in the rat brain determined by high speed cyclic voltammetry. Brain Res 299:289-295.
43. Studer L, Tabar V, McKay R. 1998. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci 1:290-295.
44. Suzukawa K, Miura K, Mitsushita J, Resau J, Hirose K, Crystal R, Kamata T. 2000. Nerve growth factor-induced neuronal differentiation requires generation of Racl-regulated reactive oxygen species. J Biol Chem 275:13175-13178.
45. Tanigaki K, Nogaki F, Takahashi J, Tashiro K, Kurooka H, Honjo T. 2001. Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate. Neuron 29:45-55.
46. +-dependent L-ascorbic acid transporters. Nature 399:70-75.
47. Vera JC, Rivas CI, Fischbarg J. 1993. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid. Nature 364:79-82.
48. Xiao G, Cui Y, Ducy P, Karsenty G, Franceschi RT. 1997. Ascorbic acid-dependent activation of the osteocalcin promoter in MC3T3-E1 preosteoblast: requirement for collagen matrix synthesis and the presence of an intact OSE2 sequence. Mol Endocrinol 11:1103-1113.
49. Yan J, Studer L, McKay R. 2001. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. J Neurochem 76:307-311.
50. Zhu G, Mehler MF, Mabie PC, Kessler JA. 1999. Developmental changes in progenitor cell responsiveness to cytokines. J Neurosci Res 56:131-145.