-
1
-
-
0025773927
-
The ancient riddle of (sepsis)
-
Majno, G. (1991) The ancient riddle of (sepsis). J. Infect. Dis. 163, 937-945.
-
(1991)
J. Infect. Dis
, vol.163
, pp. 937-945
-
-
Majno, G.1
-
2
-
-
0018858071
-
The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin
-
Michalek, S. M., Moore, R. N., McGhee, J. R., Rosenstreich, D. L., Mergenhagen, S. E. (1980) The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin. J. Infect. Dis. 141, 55-63.
-
(1980)
J. Infect. Dis
, vol.141
, pp. 55-63
-
-
Michalek, S.M.1
Moore, R.N.2
McGhee, J.R.3
Rosenstreich, D.L.4
Mergenhagen, S.E.5
-
3
-
-
0019906260
-
Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli
-
Ziegler, E. J., McCutchan, J. A., Fierer, J., Glauser, M. P., Sadoff, J. C., Douglas, H., Braude, A. I. (1982) Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coli. N. Engl. J. Med. 307, 1225-1230.
-
(1982)
N. Engl. J. Med
, vol.307
, pp. 1225-1230
-
-
Ziegler, E.J.1
McCutchan, J.A.2
Fierer, J.3
Glauser, M.P.4
Sadoff, J.C.5
Douglas, H.6
Braude, A.I.7
-
4
-
-
0038482456
-
Such stuff as dreams are made on: Mediator-targeted therapy in sepsis
-
Marshall, J. C. (2003) Such stuff as dreams are made on: mediator-targeted therapy in sepsis. Nat. Rev. Drug Discov. 2, 391-405.
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 391-405
-
-
Marshall, J.C.1
-
5
-
-
0037090339
-
Clinical trials of immunomodulatory therapies in severe sepsis and septic shock
-
Vincent, J-L., Sun, Q., Dubois, M-J. (2002) Clinical trials of immunomodulatory therapies in severe sepsis and septic shock. Clin. Infect. Dis. 34, 1084-1093.
-
(2002)
Clin. Infect. Dis
, vol.34
, pp. 1084-1093
-
-
Vincent, J.-L.1
Sun, Q.2
Dubois, M.-J.3
-
6
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) Study Group
-
Bernard, G. R., Vincent, J-L., Laterre, P. F., LaRosa, S. P., Dhainaut, J-F., Lopez-Rodriguez, A., Steingrub, J. S., Garber, G. E., Helterbrand, J. D., Ely, E. W., Fisher Jr., C. J., Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) Study Group (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N. Engl. J. Med. 344, 699-709.
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.-L.2
Laterre, P.F.3
LaRosa, S.P.4
Dhainaut, J.-F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher Jr., C.J.11
-
7
-
-
0037251850
-
Recombinant human activated protein C in sepsis: Inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials
-
Eichacker, P. Q., Natanson, C. (2003) Recombinant human activated protein C in sepsis: inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials. Crit. Care Med. 31 (Suppl. 1), S94-S96.
-
(2003)
Crit. Care Med
, vol.31
, Issue.SUPPL. 1
-
-
Eichacker, P.Q.1
Natanson, C.2
-
8
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane, D., Sebille, V., Charpentier, C., Bollaert, P-E., Francois, B., Korach, J-M., Capellier, G., Cohen, Y., Azoulay, E., Troche, G., et al. (2002) Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288, 862-871.
-
(2002)
JAMA
, vol.288
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
Bollaert, P.-E.4
Francois, B.5
Korach, J.-M.6
Capellier, G.7
Cohen, Y.8
Azoulay, E.9
Troche, G.10
-
9
-
-
33847009520
-
Meta-analysis: Intravenous immunoglobulin in critically ill adult patients with sepsis
-
Turgeon, A. F., Hutton, B., Fergusson, D. A., McIntyre, L., Tinmouth, A. A., Cameron, D. W., Hébert, P. C. (2007) Meta-analysis: intravenous immunoglobulin in critically ill adult patients with sepsis. Ann. Intern. Med. 146, 193-203.
-
(2007)
Ann. Intern. Med
, vol.146
, pp. 193-203
-
-
Turgeon, A.F.1
Hutton, B.2
Fergusson, D.A.3
McIntyre, L.4
Tinmouth, A.A.5
Cameron, D.W.6
Hébert, P.C.7
-
10
-
-
8544262221
-
Efficacy and safety of the monoclonal anti-TNF antibody F(ab′)2 fragment in patients with severe sepsis stratified by IL-6 level
-
Panacek, E. A., Marshall, J. C., Albertson, T. E., Johnson, D. H., Johnson, S. B., MacArthur, R. D., Miller, M. A., Barchuk, W. T., Fischkoff, S., Kaul, M., et al. (2004) Efficacy and safety of the monoclonal anti-TNF antibody F(ab′)2 fragment in patients with severe sepsis stratified by IL-6 level. Crit. Care Med. 32, 2173-2182.
-
(2004)
Crit. Care Med
, vol.32
, pp. 2173-2182
-
-
Panacek, E.A.1
Marshall, J.C.2
Albertson, T.E.3
Johnson, D.H.4
Johnson, S.B.5
MacArthur, R.D.6
Miller, M.A.7
Barchuk, W.T.8
Fischkoff, S.9
Kaul, M.10
-
11
-
-
30044435348
-
Drotrecogin α (activated) in severe sepsis
-
Friedrich, J. O. (2006) Drotrecogin α (activated) in severe sepsis. N. Engl. J. Med. 354, 94-96.
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 94-96
-
-
Friedrich, J.O.1
-
12
-
-
0024333745
-
Sepsis syndrome: A valid clinical entity. Methylprednisolone Severe Sepsis Study Group
-
Bone, R. C., Fisher, C. J., Clemmer, T. P., Slotman, G. J., Metz, C. A., Balk, R. A. (1989) Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group. Crit. Care Med. 17, 389-393.
-
(1989)
Crit. Care Med
, vol.17
, pp. 389-393
-
-
Bone, R.C.1
Fisher, C.J.2
Clemmer, T.P.3
Slotman, G.J.4
Metz, C.A.5
Balk, R.A.6
-
13
-
-
0023252009
-
A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock
-
Bone, R. C., Fisher, C. J., Clemmer, T. P., Slotman, G. J., Metz, C. A., Balk, R. A. (1987) A controlled clinical trial of high-dose methylprednisolone in the treatment of severe sepsis and septic shock. N. Engl. J. Med. 317, 653-658.
-
(1987)
N. Engl. J. Med
, vol.317
, pp. 653-658
-
-
Bone, R.C.1
Fisher, C.J.2
Clemmer, T.P.3
Slotman, G.J.4
Metz, C.A.5
Balk, R.A.6
-
14
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
Chest
-
Bone, R. C., Balk, R. A., Cerra, F. B., Dellinger, R. P., Fein, A. M., Knaus, W. A., Schein, R. M. H., Sibbald, W. J. (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101, 1644-1655.
-
(1992)
The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.H.7
Sibbald, W.J.8
-
15
-
-
0027731546
-
Plasma cytokines and endotoxin levels correlate with survival in patients with the sepsis syndrome
-
Casey, L. C., Balk, R. A., Bone, R. C. (1993) Plasma cytokines and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann. Intern. Med. 119, 771-778.
-
(1993)
Ann. Intern. Med
, vol.119
, pp. 771-778
-
-
Casey, L.C.1
Balk, R.A.2
Bone, R.C.3
-
16
-
-
17344373215
-
Limulus amebocyte lysate assay for detection of endotoxin in patients with sepsis syndrome. AMCC Sepsis Project Working Group
-
Bates, D. W., Parsonnet, J., Ketchum, P. A., Miller, E. B., Novitsky, T. J., Sands, K., Hibberd, P. L., Graman, P. S., Lanken, P. N., Schwartz, J. S., et al. (1998) Limulus amebocyte lysate assay for detection of endotoxin in patients with sepsis syndrome. AMCC Sepsis Project Working Group. Clin. Infect. Dis. 27, 582-591.
-
(1998)
Clin. Infect. Dis
, vol.27
, pp. 582-591
-
-
Bates, D.W.1
Parsonnet, J.2
Ketchum, P.A.3
Miller, E.B.4
Novitsky, T.J.5
Sands, K.6
Hibberd, P.L.7
Graman, P.S.8
Lanken, P.N.9
Schwartz, J.S.10
-
17
-
-
0027489283
-
Endotoxemia after major vascular operations
-
Roumen, R. M. H., Frieling, J. T. M., van Tits, H. W., van der Vliet, J. A., Goris, R. J. (1993) Endotoxemia after major vascular operations. J. Vasc. Surg. 18, 853-857.
-
(1993)
J. Vasc. Surg
, vol.18
, pp. 853-857
-
-
Roumen, R.M.H.1
Frieling, J.T.M.2
van Tits, H.W.3
van der Vliet, J.A.4
Goris, R.J.5
-
18
-
-
0034118453
-
Endotoxin and antiendotoxin antibodies in patients with acute pancreatitis
-
Buttenschoen, K., Berger, D., Hiki, N., Buttenschoen, D. C., Vasilescu, C., Chikh-Torab, F., Seidelmann, M., Beger, H. G. (2000) Endotoxin and antiendotoxin antibodies in patients with acute pancreatitis. Eur. J. Surg. 166, 459-466.
-
(2000)
Eur. J. Surg
, vol.166
, pp. 459-466
-
-
Buttenschoen, K.1
Berger, D.2
Hiki, N.3
Buttenschoen, D.C.4
Vasilescu, C.5
Chikh-Torab, F.6
Seidelmann, M.7
Beger, H.G.8
-
19
-
-
3042785468
-
Diagnostic and prognostic implications of endotoxemia in critical illness: Results of the MEDIC study
-
Marshall, J. C., Foster, D., Vincent, J-L., Cook, D. J., Dellinger, R. P., Opal, S., Abraham, E., Brett, S., Smith, T., Mehta, S., Derzko, A., Romaschin, A. (2004) Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J. Infect. Dis. 190, 527-534.
-
(2004)
J. Infect. Dis
, vol.190
, pp. 527-534
-
-
Marshall, J.C.1
Foster, D.2
Vincent, J.-L.3
Cook, D.J.4
Dellinger, R.P.5
Opal, S.6
Abraham, E.7
Brett, S.8
Smith, T.9
Mehta, S.10
Derzko, A.11
Romaschin, A.12
-
20
-
-
0022411888
-
Passive immunization against cachectin tumor necrosis factor protects mice from lethal effect of endotoxin
-
Beutler, B., Milsark, I. W., Cerami, A. C. (1985) Passive immunization against cachectin tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229, 869-871.
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.C.3
-
21
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in the Tlr4 gene
-
Poltorak, A., He, X., Smirnova, I., Liu, M-Y., van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in the Tlr4 gene. Science 282, 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.-Y.4
van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
22
-
-
0022230197
-
Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product
-
Anderson, K. V., Jürgens, G., Nüsslein-Vollhard, C. (1985) Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product. Cell 42, 779-789.
-
(1985)
Cell
, vol.42
, pp. 779-789
-
-
Anderson, K.V.1
Jürgens, G.2
Nüsslein-Vollhard, C.3
-
23
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., Uematsu, S., Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124, 783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
24
-
-
0035980651
-
Macrophage migration inhibitory factor (MIF) transcription is significantly elevated in Caenorhabditis elegans dauer larvae
-
Marson, A. L., Tarr, D. E., Scott, A. L. (2001) Macrophage migration inhibitory factor (MIF) transcription is significantly elevated in Caenorhabditis elegans dauer larvae. Gene 278, 53-62.
-
(2001)
Gene
, vol.278
, pp. 53-62
-
-
Marson, A.L.1
Tarr, D.E.2
Scott, A.L.3
-
25
-
-
0025255636
-
The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
-
Yuan, J. Y., Horvitz, H. R. (1990) The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev. Biol. 138, 33-41.
-
(1990)
Dev. Biol
, vol.138
, pp. 33-41
-
-
Yuan, J.Y.1
Horvitz, H.R.2
-
26
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
-
Miura, M., Zhu, H., Rotello, R., Hartwieg, E. A., Yuan, J. (1993) Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75, 653-660.
-
(1993)
Cell
, vol.75
, pp. 653-660
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
Hartwieg, E.A.4
Yuan, J.5
-
27
-
-
33748793685
-
Physiological functions of caspases beyond cell death
-
Nhan, T. Q., Liles, W. C., Schwartz, S. M. (2006) Physiological functions of caspases beyond cell death. Am. J. Pathol. 169, 729-737.
-
(2006)
Am. J. Pathol
, vol.169
, pp. 729-737
-
-
Nhan, T.Q.1
Liles, W.C.2
Schwartz, S.M.3
-
28
-
-
1642619114
-
Increased gene expression of a cytokine-related molecule and profilin after activation of Suberites domuncula cells with zenogeneic sponge molecule(s)
-
Muller, W. E., Perovic, S., Wilkesman, J., Kruse, M., Muller, I. M., Batel, R. (1999) Increased gene expression of a cytokine-related molecule and profilin after activation of Suberites domuncula cells with zenogeneic sponge molecule(s). DNA Cell Biol. 18, 885-893.
-
(1999)
DNA Cell Biol
, vol.18
, pp. 885-893
-
-
Muller, W.E.1
Perovic, S.2
Wilkesman, J.3
Kruse, M.4
Muller, I.M.5
Batel, R.6
-
29
-
-
85047693796
-
Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
-
Jia, S. H., Li, Y., Parodo, J., Kapus, A., Fan, L., Rotstein, O. D., Marshall, J. C. (2004) Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. J. Clin. Invest. 113, 1318-1327.
-
(2004)
J. Clin. Invest
, vol.113
, pp. 1318-1327
-
-
Jia, S.H.1
Li, Y.2
Parodo, J.3
Kapus, A.4
Fan, L.5
Rotstein, O.D.6
Marshall, J.C.7
-
30
-
-
0035145516
-
Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence
-
Martin, P. R., Shea, R. J., Mulks, M. H. (2001) Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence. J. Bacteriol. 183, 1168-1174.
-
(2001)
J. Bacteriol
, vol.183
, pp. 1168-1174
-
-
Martin, P.R.1
Shea, R.J.2
Mulks, M.H.3
-
31
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
Calvano, S. E., Xiao, W., Richards, D. R., Felciano, R. M., Baker, H. V., Cho, R. J., Chen, R. O., Brownstein, B. H., Cobb, J. P., Tschoeke, S. K., et al. (2005) A network-based analysis of systemic inflammation in humans. Nature 437, 1032-1037.
-
(2005)
Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
Chen, R.O.7
Brownstein, B.H.8
Cobb, J.P.9
Tschoeke, S.K.10
-
32
-
-
0030595339
-
The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre, B., Nicolas, E., Michaut, L., Reichhart, J. M., Hoffmann, J. A. (1996) The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86, 973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
33
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signaling
-
O'Neill, L. A., Bowie, A. G. (2007) The family of five: TIR-domain-containing adaptors in Toll-like receptor signaling. Nat. Rev. Immunol. 7, 353-364.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
34
-
-
2942627626
-
Hydrophobicity: An ancient damage-associated molecular pattern that initiates innate immune responses
-
Seong, S. Y., Matzinger, P. (2004) Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat. Rev. Immunol. 4, 469-478.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 469-478
-
-
Seong, S.Y.1
Matzinger, P.2
-
35
-
-
33846319348
-
The innate signaling of dangers and the dangers of innate signaling
-
Sansonetti, P. J. (2006) The innate signaling of dangers and the dangers of innate signaling. Nat. Immunol. 7, 1237-1242.
-
(2006)
Nat. Immunol
, vol.7
, pp. 1237-1242
-
-
Sansonetti, P.J.1
-
36
-
-
33947629255
-
Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
-
Miyake, K. (2007) Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin. Immunol. 19, 3-10.
-
(2007)
Semin. Immunol
, vol.19
, pp. 3-10
-
-
Miyake, K.1
-
37
-
-
3242664636
-
Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., Medzhitov, R. (2004) Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis. Cell 118, 229-241.
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
38
-
-
33845284823
-
Toll-like receptor signaling in intestinal epithelial cells contributes to colonic homoeostasis
-
Lee, J., Mo, J. H., Shen, C., Rucker, A. N., Raz, E. (2007) Toll-like receptor signaling in intestinal epithelial cells contributes to colonic homoeostasis. Curr. Opin. Gastroenterol. 23, 27-31.
-
(2007)
Curr. Opin. Gastroenterol
, vol.23
, pp. 27-31
-
-
Lee, J.1
Mo, J.H.2
Shen, C.3
Rucker, A.N.4
Raz, E.5
-
39
-
-
33646786804
-
Neutralization of tumor necrosis factor (TNF) in pre-clinical models of sepsis
-
Lorente, J. A., Marshall, J. C. (2005) Neutralization of tumor necrosis factor (TNF) in pre-clinical models of sepsis. Shock 24 (Suppl. 1), 107-119.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
, pp. 107-119
-
-
Lorente, J.A.1
Marshall, J.C.2
-
40
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
Bongartz, T., Sutton, A. J., Sweeting, M. J., Buchan, I., Matteson, E. L., Montori, V. (2006) Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA 295, 2275-2285.
-
(2006)
JAMA
, vol.295
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
41
-
-
0000955941
-
The fecal flora of various strains of mice. Its bearing on their susceptibility to endotoxin
-
Schaedler, R. W., Dubos, R. J. (1962) The fecal flora of various strains of mice. Its bearing on their susceptibility to endotoxin. J. Exp. Med. 115, 1149-1159.
-
(1962)
J. Exp. Med
, vol.115
, pp. 1149-1159
-
-
Schaedler, R.W.1
Dubos, R.J.2
-
42
-
-
33646786804
-
Pre-clinical models of sepsis: What can they tell us?
-
Marshall, J. C., Deitch, E. A., Moldawer, L. L., Opal, S., Redl, H., van der Poll, T. (2005) Pre-clinical models of sepsis: what can they tell us? Shock 24 (Suppl. 1), 107-119.
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
, pp. 107-119
-
-
Marshall, J.C.1
Deitch, E.A.2
Moldawer, L.L.3
Opal, S.4
Redl, H.5
van der6
Poll, T.7
-
43
-
-
34547539688
-
Empiric antimicrobial therapy in critical illness: Results of a surgical infection society survey
-
Aarts, M. A., Granton, J., Cook, D., Bohnen, J., Marshall, J. C. (2007) Empiric antimicrobial therapy in critical illness: results of a surgical infection society survey. Surg. Infect. (Larchmt) 8, 329-336.
-
(2007)
Surg. Infect. (Larchmt)
, vol.8
, pp. 329-336
-
-
Aarts, M.A.1
Granton, J.2
Cook, D.3
Bohnen, J.4
Marshall, J.C.5
-
44
-
-
33947168829
-
Signaling pathways activated by microorganisms
-
Takeuchi, O., Akira, S. (2007) Signaling pathways activated by microorganisms. Curr. Opin. Cell Biol. 19, 185-191.
-
(2007)
Curr. Opin. Cell Biol
, vol.19
, pp. 185-191
-
-
Takeuchi, O.1
Akira, S.2
-
45
-
-
0037226672
-
Mal and MyD88: Adapter proteins involved in signal transduction by Toll-like receptors
-
O'Neill, L. A., Dunne, A., Edjeback, M., Gray, P., Jefferies, C., Wietek, C. (2003) Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors. J. Endotoxin Res. 9, 55-59.
-
(2003)
J. Endotoxin Res
, vol.9
, pp. 55-59
-
-
O'Neill, L.A.1
Dunne, A.2
Edjeback, M.3
Gray, P.4
Jefferies, C.5
Wietek, C.6
-
46
-
-
34047098731
-
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis
-
Khor, C. C., Chapman, S. J., Vannberg, F. O., Dunne, A., Murphy, C., Ling, E. Y., Frodsham, A. J., Walley, A. J., Kyrieleis, O., Khan, A., et al. (2007) A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat. Genet. 39, 523-528.
-
(2007)
Nat. Genet
, vol.39
, pp. 523-528
-
-
Khor, C.C.1
Chapman, S.J.2
Vannberg, F.O.3
Dunne, A.4
Murphy, C.5
Ling, E.Y.6
Frodsham, A.J.7
Walley, A.J.8
Kyrieleis, O.9
Khan, A.10
-
47
-
-
0037804774
-
Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia
-
Branger, J., van den Blink, B., Weijer, S., Gupta, A., van Deventer, S. J., Hack, C. E., Peppelenbosch, M. P., van der Poll, T. (2003) Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia. Blood 101, 4446-4448.
-
(2003)
Blood
, vol.101
, pp. 4446-4448
-
-
Branger, J.1
van den Blink, B.2
Weijer, S.3
Gupta, A.4
van Deventer, S.J.5
Hack, C.E.6
Peppelenbosch, M.P.7
van der Poll, T.8
-
48
-
-
0037442501
-
Blocking of responses to endotoxin by E5564 in healthy volunteers with experimental endotoxemia
-
Lynn, M., Rossignol, D. P., Wheeler, J. L., Kao, R. J., Perdomo, C. A., Noveck, R., Vargas, R., D'Angelo, T., Gotzkowsky, S., McMahon, F. G. (2003) Blocking of responses to endotoxin by E5564 in healthy volunteers with experimental endotoxemia. J. Infect. Dis. 187, 631-639.
-
(2003)
J. Infect. Dis
, vol.187
, pp. 631-639
-
-
Lynn, M.1
Rossignol, D.P.2
Wheeler, J.L.3
Kao, R.J.4
Perdomo, C.A.5
Noveck, R.6
Vargas, R.7
D'Angelo, T.8
Gotzkowsky, S.9
McMahon, F.G.10
-
49
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin, G. S., Mannino, D. M., Eaton, S., Moss, M. (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348, 1546-1554.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
50
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus, D. C., Linde-Zwirble, W. T., Lidicker, J., Clermont, G., Carcillo, J., Pinsky, M. R. (2001) Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 29, 1303-1310.
-
(2001)
Crit. Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
51
-
-
0030733447
-
-
Muckart, D. J., Bhagwanjee, S. (1997) American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients. Crit. Care Med. 25, 1789-1795.
-
Muckart, D. J., Bhagwanjee, S. (1997) American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients. Crit. Care Med. 25, 1789-1795.
-
-
-
-
52
-
-
0028893025
-
The natural history of the systemic inflammatory response syndrome (SIRS): A prospective study
-
Rangel-Frausto, M. S., Pittet, D., Costigan, M., Hwang, T., Davis, C. S., Wenzel, R. P. (1995) The natural history of the systemic inflammatory response syndrome (SIRS): a prospective study. JAMA 273, 117-123.
-
(1995)
JAMA
, vol.273
, pp. 117-123
-
-
Rangel-Frausto, M.S.1
Pittet, D.2
Costigan, M.3
Hwang, T.4
Davis, C.S.5
Wenzel, R.P.6
-
53
-
-
0025021527
-
Microbial infection and the septic response in critical surgical illness. Sepsis, not infection, determines outcome
-
Marshall, J. C., Sweeney, D. (1990) Microbial infection and the septic response in critical surgical illness. Sepsis, not infection, determines outcome. Arch. Surg. 125, 17-22.
-
(1990)
Arch. Surg
, vol.125
, pp. 17-22
-
-
Marshall, J.C.1
Sweeney, D.2
-
54
-
-
0032874915
-
Historic perspectives on the relative contributions of diastolic and systolic blood pressure elevation to cardiovascular risk profile
-
Kannel, W. B. (1999) Historic perspectives on the relative contributions of diastolic and systolic blood pressure elevation to cardiovascular risk profile. Am. Heart J. 138, 205-210.
-
(1999)
Am. Heart J
, vol.138
, pp. 205-210
-
-
Kannel, W.B.1
-
55
-
-
0032240617
-
History and international developments in cancer staging
-
Gospodarowicz, M., Benedet, L., Hutter, R. V., Flemimg, I., Henson, D. E., Sobin, L. H. (1998) History and international developments in cancer staging. Cancer Prev. Control 2, 262-268.
-
(1998)
Cancer Prev. Control
, vol.2
, pp. 262-268
-
-
Gospodarowicz, M.1
Benedet, L.2
Hutter, R.V.3
Flemimg, I.4
Henson, D.E.5
Sobin, L.H.6
-
56
-
-
34247588117
-
Acute lung injury and the acute respiratory distress syndrome: A clinical review
-
Wheeler, A. P., Bernard, G. R. (2007) Acute lung injury and the acute respiratory distress syndrome: a clinical review. Lancet 369, 1553-1564.
-
(2007)
Lancet
, vol.369
, pp. 1553-1564
-
-
Wheeler, A.P.1
Bernard, G.R.2
-
57
-
-
0343893748
-
-
Ventilation with lower tidal as compared with traditional tidal for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 342, 1301-1308
-
(2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 342, 1301-1308.
-
-
-
-
58
-
-
0345436055
-
Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome. A randomized controlled trial
-
Ranieri, V. M., Suter, P. M., Tortorella, C., de Tullio, R., Dayer, J. M., Brienza, A., Bruno, F., Slutsky, A. S. (1999) Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome. A randomized controlled trial. JAMA 282, 54-61.
-
(1999)
JAMA
, vol.282
, pp. 54-61
-
-
Ranieri, V.M.1
Suter, P.M.2
Tortorella, C.3
de Tullio, R.4
Dayer, J.M.5
Brienza, A.6
Bruno, F.7
Slutsky, A.S.8
-
59
-
-
0038324005
-
Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome
-
Imai, Y., Parodo, J., Kajikawa, O., de Perrot, M., Fischer, S., Edwards, V., Cutz, E., Liu, M., Keshavjee, S., Martin, T. R., et al. (2003) Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 289, 2104-2112.
-
(2003)
JAMA
, vol.289
, pp. 2104-2112
-
-
Imai, Y.1
Parodo, J.2
Kajikawa, O.3
de Perrot, M.4
Fischer, S.5
Edwards, V.6
Cutz, E.7
Liu, M.8
Keshavjee, S.9
Martin, T.R.10
-
60
-
-
0343360868
-
A multicentre randomized controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group
-
Hebert, P. C., Wells, G., Blajchman, M. A., Marshall, J., Martin, C., Pagliarello, G., Tweeddale, M., Schweitzer, I., Yetisir, E. (1999) A multicentre randomized controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group. N. Engl. J. Med. 340, 409-417.
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 409-417
-
-
Hebert, P.C.1
Wells, G.2
Blajchman, M.A.3
Marshall, J.4
Martin, C.5
Pagliarello, G.6
Tweeddale, M.7
Schweitzer, I.8
Yetisir, E.9
-
61
-
-
0034682246
-
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation
-
Kress, J. P., Pohlman, A. S., O'Connor, M. F., Hall, J. B. (2000) Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N. Engl. J. Med. 342, 1471-1477.
-
(2000)
N. Engl. J. Med
, vol.342
, pp. 1471-1477
-
-
Kress, J.P.1
Pohlman, A.S.2
O'Connor, M.F.3
Hall, J.B.4
-
62
-
-
0023708461
-
Diagnosis of nosocomial bacterial pneumonia in intubated patients undergoing ventilation: Comparison of the usefulness of bronchoalveolar lavage and protected specimen brush
-
Chastre, J., Fagon, J. Y., Soler, P., Bornet, M., Domart, Y., Trouillet, J. L., Gibert, C., Hance, A. J. (1988) Diagnosis of nosocomial bacterial pneumonia in intubated patients undergoing ventilation: comparison of the usefulness of bronchoalveolar lavage and protected specimen brush. Am. J. Med. 85, 499-506.
-
(1988)
Am. J. Med
, vol.85
, pp. 499-506
-
-
Chastre, J.1
Fagon, J.Y.2
Soler, P.3
Bornet, M.4
Domart, Y.5
Trouillet, J.L.6
Gibert, C.7
Hance, A.J.8
-
63
-
-
31344461826
-
Sepsis in European intensive care units: Results of the SOAP study
-
Vincent, J-L., Sakr, Y., Sprung, C. L., Ranieri, V. M., Reinhart, K., Gerlach, H., Moreno, R., Carlet, J., Le Gall, R., Payen, D. (2006) Sepsis in European intensive care units: results of the SOAP study. Crit. Care Med. 34, 344-353.
-
(2006)
Crit. Care Med
, vol.34
, pp. 344-353
-
-
Vincent, J.-L.1
Sakr, Y.2
Sprung, C.L.3
Ranieri, V.M.4
Reinhart, K.5
Gerlach, H.6
Moreno, R.7
Carlet, J.8
Le Gall, R.9
Payen, D.10
-
64
-
-
3242775982
-
Surviving sepsis campaign guidelines for management of severe sepsis and septic shock
-
Dellinger, R. P., Carlet, J. M., Masur, H., Gerlach, H., Calandra, T., Cohen, J., Moreno, R., Carlet, J., Le Gall, R., Payen, D. (2004) Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit. Care Med. 32, 858-873.
-
(2004)
Crit. Care Med
, vol.32
, pp. 858-873
-
-
Dellinger, R.P.1
Carlet, J.M.2
Masur, H.3
Gerlach, H.4
Calandra, T.5
Cohen, J.6
Moreno, R.7
Carlet, J.8
Le Gall, R.9
Payen, D.10
-
65
-
-
1642596843
-
FDA perspective on study design for therapies for severe sepsis
-
Schwieterman, W., Roberts, R. (1997) FDA perspective on study design for therapies for severe sepsis. Sepsis 1, 69.
-
(1997)
Sepsis
, vol.1
, pp. 69
-
-
Schwieterman, W.1
Roberts, R.2
-
66
-
-
0032495658
-
Double-blind randomized controlled trial of monoclonal antibody to human tumor necrosis factor in treatment of septic shock. NORASEPT II Study Group
-
Abraham, E., Anzueto, A., Gutierrez, G., Tessler, S., San Pedro, G., Wunderink, R., Dal Nogare, A., Nasraway, S., Berman, S., Cooney, R., et al. (1998) Double-blind randomized controlled trial of monoclonal antibody to human tumor necrosis factor in treatment of septic shock. NORASEPT II Study Group. Lancet 351, 929-933.
-
(1998)
Lancet
, vol.351
, pp. 929-933
-
-
Abraham, E.1
Anzueto, A.2
Gutierrez, G.3
Tessler, S.4
San Pedro, G.5
Wunderink, R.6
Dal Nogare, A.7
Nasraway, S.8
Berman, S.9
Cooney, R.10
-
67
-
-
4444273012
-
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: Effect on survival in patients with septic shock
-
Lopez, A., Lorente, J. A., Steingrub, J., Bakker, J., McLuckie, A., Willatts, S., Brockway, M., Anzueto, A., Holzapfel, L., Breen, D., et al. (2004) Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit. Care Med. 32, 21-30.
-
(2004)
Crit. Care Med
, vol.32
, pp. 21-30
-
-
Lopez, A.1
Lorente, J.A.2
Steingrub, J.3
Bakker, J.4
McLuckie, A.5
Willatts, S.6
Brockway, M.7
Anzueto, A.8
Holzapfel, L.9
Breen, D.10
-
68
-
-
0038690407
-
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial
-
Abraham, E., Reinhart, K., Opal, S., Demeyer, I., Doig, C., Rodriguez, A. L., Beale, R., Svoboda, P., Laterre, P. F., Simon, S., et al. (2003) Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA 290, 238-247.
-
(2003)
JAMA
, vol.290
, pp. 238-247
-
-
Abraham, E.1
Reinhart, K.2
Opal, S.3
Demeyer, I.4
Doig, C.5
Rodriguez, A.L.6
Beale, R.7
Svoboda, P.8
Laterre, P.F.9
Simon, S.10
-
69
-
-
0029115513
-
Long-term survival and function after suspected gram-negative sepsis
-
Perl, T. M., Dvorak, L., Hwang, T., Wenzel, R. P. (1995) Long-term survival and function after suspected gram-negative sepsis. JAMA 274, 338-345.
-
(1995)
JAMA
, vol.274
, pp. 338-345
-
-
Perl, T.M.1
Dvorak, L.2
Hwang, T.3
Wenzel, R.P.4
-
70
-
-
33947667912
-
Influence of comorbid conditions on long-term mortality after pneumonia in older people
-
Yende, S., Angus, D. C., Ali, I. S., Somes, G., Newman, A. B., Bauer, D., Garcia, M., Harris, T. B., Kritchevsky, S. B. (2007) Influence of comorbid conditions on long-term mortality after pneumonia in older people. J. Am. Geriatr. Soc. 55, 518-525.
-
(2007)
J. Am. Geriatr. Soc
, vol.55
, pp. 518-525
-
-
Yende, S.1
Angus, D.C.2
Ali, I.S.3
Somes, G.4
Newman, A.B.5
Bauer, D.6
Garcia, M.7
Harris, T.B.8
Kritchevsky, S.B.9
-
71
-
-
0035054111
-
New strategies for clinical trials in patients with sepsis and septic shock
-
Cohen, J., Guyatt, G., Bernard, G. R., Calandra, T., Cook, D., Elebourne, D., Marshall, J., Nunn, A., Opal, S. (2001) New strategies for clinical trials in patients with sepsis and septic shock. Crit. Care Med. 29, 880-886.
-
(2001)
Crit. Care Med
, vol.29
, pp. 880-886
-
-
Cohen, J.1
Guyatt, G.2
Bernard, G.R.3
Calandra, T.4
Cook, D.5
Elebourne, D.6
Marshall, J.7
Nunn, A.8
Opal, S.9
-
72
-
-
23844501676
-
Outcome measures for clinical research in sepsis: A report of the 2nd Cambridge Colloquium of the International Sepsis Forum
-
Marshall, J. C., Vincent, J. L., Guyatt, G., Angus, D. C., Abraham, E., Bernard, G., Bombardier, C., Calandra, T., Jorgensen, H. S., Sylvester, R., Boers, M. (2005) Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis Forum. Crit. Care Med. 33, 1708-1716.
-
(2005)
Crit. Care Med
, vol.33
, pp. 1708-1716
-
-
Marshall, J.C.1
Vincent, J.L.2
Guyatt, G.3
Angus, D.C.4
Abraham, E.5
Bernard, G.6
Bombardier, C.7
Calandra, T.8
Jorgensen, H.S.9
Sylvester, R.10
Boers, M.11
-
73
-
-
0032241954
-
The role of cancer staging in evidence-based medicine
-
Mackillop, W. J., O'Sullivan, B., Gospodarowicz, M. (1998) The role of cancer staging in evidence-based medicine. Cancer Prev. Control 2, 269-277.
-
(1998)
Cancer Prev. Control
, vol.2
, pp. 269-277
-
-
Mackillop, W.J.1
O'Sullivan, B.2
Gospodarowicz, M.3
-
74
-
-
0037904920
-
Measures, markers, and mediators: Towards a staging system for clinical sepsis
-
Marshall, J. C., Vincent, J-L., Fink, M. P., Cook, D. J., Rubenfeld, G., Foster, D., Faist, E., Reinhart, K. (2003) Measures, markers, and mediators: towards a staging system for clinical sepsis. Crit. Care Med. 31, 1560-1567.
-
(2003)
Crit. Care Med
, vol.31
, pp. 1560-1567
-
-
Marshall, J.C.1
Vincent, J.-L.2
Fink, M.P.3
Cook, D.J.4
Rubenfeld, G.5
Foster, D.6
Faist, E.7
Reinhart, K.8
-
75
-
-
0037389094
-
-
Levy, M. M., Fink, M., Marshall, J. C., Abraham, E., Angus, D., Cook, D., Cohen, J., Opal, S. M., Vincent, J-L., Ramsay, G. (2003) 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit. Care Med. 31, 1250-1256.
-
Levy, M. M., Fink, M., Marshall, J. C., Abraham, E., Angus, D., Cook, D., Cohen, J., Opal, S. M., Vincent, J-L., Ramsay, G. (2003) 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit. Care Med. 31, 1250-1256.
-
-
-
-
76
-
-
0023870774
-
Genetic and environmental influences on premature death in adult adoptees
-
Sørensen, T. I., Nielsen, G. G., Andersen, P. K., Teasdale, P. W. (1988) Genetic and environmental influences on premature death in adult adoptees. N. Engl. J. Med. 318, 727-732.
-
(1988)
N. Engl. J. Med
, vol.318
, pp. 727-732
-
-
Sørensen, T.I.1
Nielsen, G.G.2
Andersen, P.K.3
Teasdale, P.W.4
-
77
-
-
0141800036
-
Genetic polymorphisms in sepsis and septic shock: Role in prognosis and potential for therapy
-
Holmes, C. L., Russell, J. A., Walley, K. R. (2003) Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy. Chest 124, 1103-1115.
-
(2003)
Chest
, vol.124
, pp. 1103-1115
-
-
Holmes, C.L.1
Russell, J.A.2
Walley, K.R.3
-
78
-
-
0033546610
-
Association of TNF2, a TNF-α promoter polymorphism, with septic shock susceptibility and mortality
-
Mira, J-P., Cariou, A., Grall, F., Delclaux, C., Losser, M-R., Heshmati, F., Cheval, C., Monchi, M., Teboul, J-L., Riche, F., et al. (1999) Association of TNF2, a TNF-α promoter polymorphism, with septic shock susceptibility and mortality. JAMA 282, 561-568.
-
(1999)
JAMA
, vol.282
, pp. 561-568
-
-
Mira, J.-P.1
Cariou, A.2
Grall, F.3
Delclaux, C.4
Losser, M.-R.5
Heshmati, F.6
Cheval, C.7
Monchi, M.8
Teboul, J.-L.9
Riche, F.10
-
79
-
-
33846138651
-
Association of TNF-α -308 G/A polymorphism with responsiveness to TNF-α-blockers in rheumatoid arthritis: A meta-analysis
-
Lee, Y. H., Rho, Y. H., Choi, S. J., Ji, J. D., Song, G. G. (2006) Association of TNF-α -308 G/A polymorphism with responsiveness to TNF-α-blockers in rheumatoid arthritis: a meta-analysis. Rheumatol. Int. 27, 157-161.
-
(2006)
Rheumatol. Int
, vol.27
, pp. 157-161
-
-
Lee, Y.H.1
Rho, Y.H.2
Choi, S.J.3
Ji, J.D.4
Song, G.G.5
-
80
-
-
9344246862
-
Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo- controlled, dose-ranging study
-
Reinhart, K., Wiegand-Löhnert, C., Grimminger, F., Kaul, M., Withington, S., Treacher, D., Eckart, J., Willatts, S., Bouza, C., Krausch, D., et al. (1996) Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: a multicenter, randomized, placebo- controlled, dose-ranging study. Crit. Care Med. 24, 733-742.
-
(1996)
Crit. Care Med
, vol.24
, pp. 733-742
-
-
Reinhart, K.1
Wiegand-Löhnert, C.2
Grimminger, F.3
Kaul, M.4
Withington, S.5
Treacher, D.6
Eckart, J.7
Willatts, S.8
Bouza, C.9
Krausch, D.10
-
81
-
-
0006275886
-
Effect of anti-TNF antibody on organ-specific components of MOD score. Afelimomab Study Group
-
Marshall, J. C., Albertson, T. E., Barchuk, W., van Meter, L. (2001) Effect of anti-TNF antibody on organ-specific components of MOD score. Afelimomab Study Group. Am. J. Respir. Crit. Care Med. 163, A820.
-
(2001)
Am. J. Respir. Crit. Care Med
, vol.163
-
-
Marshall, J.C.1
Albertson, T.E.2
Barchuk, W.3
van Meter, L.4
|