Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting σ1 receptors produce anti-cocaine effects in mice

European Journal of Pharmacology

Volumn 419, Issue 2-3, 2001, Pages 163-174

  Matsumoto, Rae R ^a   McCracken, Kari A ^a   Friedman, Michele J ^a   Pouw, Buddy ^a   De Costa, Brian R ^b   Bowen, Wayne D ^b  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Receptor; Antisense; Cocaine; Convulsion; Locomotor activity; Psychomotor activity; Toxicity

Indexed keywords

1 [2 (3,4 DICHLOROPHENYL)ETHYL] 1,4 DIAZABICYCLO[4.3.0]NONANE; 1 [2 (3,4 DICHLOROPHENYL)ETHYL] 4 METHYLPIPERAZINE; 4 AMINOBUTYRIC ACID A RECEPTOR; ANTISENSE OLIGODEOXYNUCLEOTIDE; BD 1018; BD 1031; BD 1063; COCAINE; DI 2 TOLYLGUANIDINE; DOPAMINE RECEPTOR; LR 132; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 (1 PYRROLIDINYL)CYCLOHEXYLAMINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)ETHYLAMINE; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)ETHYLAMINE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OPIATE AGONIST; OPIATE ANTAGONIST; OPIATE RECEPTOR; SIGMA 1 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CONVULSION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG RECEPTOR BINDING; ENANTIOMER; HYPERACTIVITY; LETHALITY; LOCOMOTION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ANALYSIS OF VARIANCE; ANIMALS; BINDING, COMPETITIVE; COCAINE; ETHYLAMINES; LOCOMOTION; MALE; MICE; MOTOR ACTIVITY; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PIPERAZINES; PYRROLIDINES; RECEPTORS, SIGMA; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035843786     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00968-2     Document Type: Article

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