Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 22, 2011, Pages 6833-6837

  Liu, Dongping ^a   Kong, Guiping ^a   Chen, Quan Cheng ^a   Wang, Guanghui ^a   Li, Jie ^a   Xu, Yang ^a   Lin, Ting ^a   Tian, Yingpu ^a   Zhang, Xiaokun ^a,b   Yao, Xinsheng ^a,c   Feng, Gensheng ^a,d   Lu, Zhongxian ^a   Chen, Haifeng ^a  

^a XIAMEN UNIVERSITY   (China)

^b BURNHAM INSTITUTE   (United States)

^c JINAN UNIVERSITY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Angelica dahurica; Cell apoptosis; Fatty acid; Shp2 inhibitors

Indexed keywords

2 HYDROXY 3 [(1 OXODODECYL)OXY]PROPYL BETA DEXTRO GLUCOPYRANOSIDE; 2,3 DIHYDROXYPROPYL DECANOATE; 3 HYDROXY 6 PYRIDINE METHANOL; ACETIC ACID ETHYL ESTER; ANTINEOPLASTIC AGENT; CAFFEIC ACID; CASPASE 3; CASPASE 8; CASPASE 9; DOTRIACONTANOIC ACID; ESTERASE INHIBITOR; FEPTADECADIENOIC ACID; HEMATOPOIETIC PROTEIN TYROSINE PHOSPHATASE; HEPTADECADIENE 4,6 DIYNE 3,8,11 TRIOL; HEXACOSADIENOIC ACID; NONADECADIENOIC ACID; OCTADECENOIC ACID; POLY(ADENOSINE DIPHOSPHATE RIBOSE); POLYUNSATURATED FATTY ACID; PROTEIN TYROSINE PHOSPHATASE SHP 2; STIGMASTEROL 3 O BETA GLUCOSIDE; TRICOSADIENOIC ACID; UNCLASSIFIED DRUG; VH1 RELATED HUMAN PROTEIN;

ANGELICA DAHURICA; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL SURVIVAL; DOSE RESPONSE; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PLANT ROOT; PROTEIN CLEAVAGE; TUMOR CELL;

ANGELICA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ENZYME INHIBITORS; FATTY ACIDS; HEP G2 CELLS; HUMANS; NEOPLASMS; PLANT EXTRACTS; PLANT ROOTS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11;

ANGELICA DAHURICA;

EID: 80054775810     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.09.023     Document Type: Article

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