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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 2, 2011, Pages 730-733

Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs

(9) Scott, Latanya M a Chen, Liwei a Daniel, Kenyon G a Brooks, Wesley H a Guida, Wayne C a,b,c Lawrence, Harshani R a Sebti, Said M a,b Lawrence, Nicholas J a,b Wu, Jie a,b

a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE (United States)

b UNIVERSITY OF SOUTH FLORIDA (United States)

c UNIVERSITY OF SOUTH FLORIDA (United States)

Author keywords

Celastrol; Enoxolone; Estramustine phosphate; Protein tyrosine phosphatase; Shp2; Triterpenoids

Indexed keywords

ANTINEOPLASTIC AGENT; CELASTROL; ENZYME INHIBITOR; ESTRADIOL; ESTRADIOL PHOSPHATE; ESTRAMUSTINE; ESTRAMUSTINE PHOSPHATE; GLYCYRRHETINIC ACID; MAITENIN; NSC 233064; PROTEIN TYROSINE PHOSPHATASE SHP 2; TRITERPENOID; TRODUSQUEMINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; ENZYME INHIBITION;

ANTINEOPLASTIC AGENTS, HORMONAL; ESTRAMUSTINE; HUMANS; MODELS, MOLECULAR; NEOPLASMS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

EID: 78651234025 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.11.117 Document Type: Article

Times cited : (37)

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