Neurobiology of obesity

Obesity: Epidemiology, Pathophysiology, and Prevention

Volumn , Issue , 2007, Pages 81-92

  Eikelis, Nina ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80054754421     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (53)

1. Wilding, J.P., Neuropeptides and appetite control, Diabet. Med., 19, 619-627, 2002.
2. Jebb, S.A., Aetiology of obesity, Br. Med. Bull., 53, 264-285, 1997.
3. Bessesen, D.H. and Faggioni, R., Recently identified peptides involved in the regulation of body weight, Semin. Oncol., 25, 28-32, 1998.
4. Bray, G.A., Treatment for obesity: a nutrient balance/nutrient partition approach, Nutr. Rev., 49, 33-45, 1991.
5. Roberts, S.B. et al., Energy expenditure and intake in infants born to lean and overweight mothers, N. Engl. J. Med., 318, 461-466, 1988.
6. Griffiths, M. et al., Metabolic rate and physical development in children at risk of obesity, Lancet, 336, 76-78, 1990.
7. Ravussin, E. et al., Reduced rate of energy expenditure as a risk factor for body-weight gain, N. Engl. J. Med., 318, 467-472, 1988.
8. Tremblay, A. et al., Overfeeding and energy expenditure in humans, Am. J. Clin. Nutr., 56, 857-862, 1992.
9. Norgan, N.G. and Durnin, J.V., The effect of 6 weeks of overfeeding on the body weight, body composition, and energy metabolism of young men, Am. J. Clin. Nutr., 33, 978-988, 1980.
10. Leibel, R.L., Rosenbaum, M., and Hirsch, J., Changes in energy expenditure resulting from altered body weight, N. Engl. J. Med., 332, 621-628, 1995.
11. Mansell, P.I. and MacDonald, I.A., The effect of underfeeding on the physiological response to food ingestion in normal weight women, Br. J. Nutr., 60, 39-48, 1988.
12. Bessard, T., Schutz, Y., and Jequier, E., Energy expenditure and postprandial thermogenesis in obese women before and after weight loss, Am. J. Clin. Nutr., 38, 680-93, 1983.
13. Perusse, L. et al., Familial aggregation of abdominal visceral fat level: results from the Quebec family study, Metabolism, 45, 378-382, 1996.
14. Zhang, Y. et al., Positional cloning of the mouse obese gene and its human homologue, Nature, 372, 425-432, 1994.
15. Fruhbeck, G., A heliocentric view of leptin, Proc. Nutr. Soc., 60, 301-318, 2001.
16. Bado, A. et al., The stomach is a source of leptin, Nature, 394, 790-793, 1998.
17. Hassink, S.G. et al., Placental leptin: an important new growth factor in intrauterine and neonatal development?, Pediatrics, 100, E1, 1997.
18. Morash, B. et al., Leptin gene expression in the brain and pituitary gland, Endocrinology, 140, 5995-5998, 1999.
19. Wiesner, G. et al., Leptin is released from the human brain: influence of adiposity and gender, J. Clin. Endocrinol. Metab., 84, 2270-2274, 1999.
20. Zhang, F. et al., Crystal structure of the obese protein leptin-E100, Nature, 387, 206-209, 1997.
21. Tartaglia, L.A. et al., Identification and expression cloning of a leptin receptor, Ob-R, Cell, 83, 1263-1271, 1995.
22. Ahima, R.S. and Flier, J.S., Leptin, Annu. Rev. Physiol., 62, 413-437, 2000.
23. Ishida-Takahashi, R. et al., Rapid inhibition of leptin signaling by glucocorticoids in vitro and in vivo, J. Biol. Chem., 279, 19658-19664, 2004.
24. Mercer, J.G. et al., Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization, FEBS Lett., 387, 113-116, 1996.
25. Fei, H. et al., Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues, Proc. Natl. Acad. Sci. USA, 94, 7001-7005, 1997.
26. Huang, L., Wang, Z., and Li, C., Modulation of circulating leptin levels by its soluble receptor, J. Biol. Chem., 276, 6343-6349, 2001.
27. Sinha, M.K. et al., Evidence of free and bound leptin in human circulation: studies in lean and obese subjects and during short-term fasting, J. Clin. Invest., 98, 1277-1282, 1996.
28. Bjorbaek, C. et al., Expression of leptin receptor isoforms in rat brain microvessels, Endocrinology, 139, 3485-3491, 1998.
29. Golden, P.L., Maccagnan, T.J., and Pardridge, W.M., Human blood-brain barrier leptin receptor:binding and endocytosis in isolated human brain microvessels, J. Clin. Invest, 99, 14-18, 1997.
30. Hileman, S.M. et al., Transcellular transport of leptin by the short leptin receptor isoform Ob-Ra in Madin-Darby canine kidney cells, Endocrinology, 141, 1955-1961, 2000.
31. Esler, M. et al., Leptin in human plasma is derived in part from the brain, and cleared by the kidneys, Lancet, 351, 879, 1998.
32. Eikelis, N. et al., Extra-adipocyte leptin release in human obesity and its relation to sympathoadrenal function, Am. J. Physiol. Endocrinol. Metab., 286, E744-E752, 2004.
33. Eikelis, N. et al., Reduced brain leptin in patients with major depressive disorder and in suicide victims, Mol. Psychiatry, 11(9), 800-801, 2006.
34. Eikelis, N. and Esler, M., The neurobiology of human obesity, Exp. Physiol., 90, 673-682, 2005.
35. Hebebrand, J. et al., Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration, Mol. Psychiatry, 2, 330-334, 1997.
36. Remschmidt, H. and Schmidt, M., Prediction of long-term outcome in anorectic patients from longitudinal weight measurements during inpatient treatment: a cross validation study, in Child and Youth Psychiatry: European Perspectives.Vol 1. Anorexia Nervosa, Remschmidt, H. and Schmidt, M., Eds., Hogrefe & Huber, Toronto, 1990, pp. 150-167.
37. Monteleone, P. et al., Leptin secretion is related to chronicity and severity of the illness in bulimia nervosa, Psychosom. Med., 64, 874-979, 2002.
38. Monteleone, P. et al., Opposite modifications in circulating leptin and soluble leptin receptor across the eating disorder spectrum, Mol. Psychiatry, 7, 641-646, 2002.
39. Jimerson, D.C. et al., Decreased serum leptin in bulimia nervosa, J. Clin. Endocrinol. Metab, 85, 4511-4514, 2000.
40. Erickson, J.C., Hollopeter, G., and Palmiter, R.D., Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y, Science, 274, 1704-1707, 1996.
41. Cusin, I. et al., The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats: reduced sensitivity compared with lean animals, Diabetes, 45, 1446-1450, 1996.
42. Banks, W.A. and Farrell, C.L., Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible, Am. J. Physiol. Endocrinol. Metab., 285, E10-E15, 2003.
43. Banks, W.A. et al., Leptin enters the brain by a saturable system independent of insulin, Peptides, 17, 305-311, 1996.
44. Banks, W.A., The many lives of leptin, Peptides, 25, 331-338, 2004.
45. Hoggard, N. et al., Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta, Proc. Natl. Acad. Sci. USA, 94, 11073-11078, 1997.
46. Wang, J. et al., A nutrient-sensing pathway regulates leptin gene expression in muscle and fat, Nature, 393, 684-688, 1998.
47. Bjorbaek, C. et al., The role of SOCS-3 in leptin signaling and leptin resistance, J. Biol. Chem., 274, 30059-30065, 1999.
48. Katsuki, A. et al., Plasma levels of agouti-related protein are increased in obese men, J. Clin. Endocrinol. Metab., 86, 1921-1924, 2001.
49. Ollmann, M.M. et al., Antagonism of central melanocortin receptors in vitro and in vivo by Agoutirelated protein, Science, 278, 135-138, 1997.
50. Kojima, M. et al., Ghrelin is a growth-hormone-releasing acylated peptide from stomach, Nature, 402, 656-660, 1999.
51. Tschop, M., Smiley, D.L., and Heiman, M.L., Ghrelin induces adiposity in rodents, Nature, 407, 908-913, 2000.
52. Kamegai, J. et al., Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats, Diabetes, 50, 2438-2443, 2001.
53. Theander-Carrillo, C. et al., Ghrelin action in the brain controls adipocyte metabolism, J. Clin. Invest., 116, 1983-1993, 2006.