Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Regala, Roderick P ^a   Justilien, Verline ^a   Walsh, Michael P ^a   Weems, Capella ^a   Khoor, Andras ^a   Murray, Nicole R ^a   Fields, Alan P ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

K RAS PROTEIN; STROMELYSIN 2; URETHAN; KRAS2 PROTEIN, MOUSE; PROTEIN P21;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC TRANSFORMATION; GENOTYPE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KRAS GENE; LUNG ALVEOLUS CELL; LUNG CANCER; MMP10 GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; STEM CELL EXPANSION; ANIMAL; BRONCHUS; C57BL MOUSE; CELL PROLIFERATION; CELL TRANSFORMATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; LUNG ALVEOLUS; LUNG TUMOR; METABOLISM; METASTASIS; PATHOLOGY; REPRODUCIBILITY; STEM CELL;

MUS;

ANIMALS; BRONCHI; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 10; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS P21(RAS); PULMONARY ALVEOLI; REPRODUCIBILITY OF RESULTS; STEM CELLS; URETHANE;

EID: 80054743546     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026439     Document Type: Article

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