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Volumn 19, Issue 9, 2011, Pages 821-829

Treatment of ricin A-chain-induced hepatotoxicity with liposome- encapsulated N-acetylcysteine

Author keywords

Antioxidants; Inflammation; Liposomes; Liver; N acetylcysteine; Oxidative stress; Reactive oxygen species

Indexed keywords

3 NITROTYROSINE; ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE; LIPOSOME; MYELOPEROXIDASE; RICIN A; TUMOR NECROSIS FACTOR ALPHA;

EID: 80054692473     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2011.582645     Document Type: Article
Times cited : (20)

References (70)
  • 1
    • 35848931018 scopus 로고    scopus 로고
    • Prophylactic effect of liposomal N-acetylcysteine against LPS-induced liver injuries
    • DOI 10.1177/0968051907085062
    • Alipour M, Omri A, Smith MG, Suntres ZE. (2007). Prophylactic effect of liposomal N-acetylcysteine against LPS-induced liver injuries. J Endotoxin Res, 13, 297-304 (Pubitemid 350056225)
    • (2007) Journal of Endotoxin Research , vol.13 , Issue.5 , pp. 297-304
    • Alipour, M.1    Omri, A.2    Smith, M.G.3    Suntres, Z.E.4
  • 2
    • 0023698992 scopus 로고
    • Toxicity of drug carriers to the mononuclear phagocyte system
    • Allen TM. (1988). Toxicity of drug carriers to the mononuclear phagocyte system. Adv Drug Deliv Rev, 2, 55-67
    • (1988) Adv Drug Deliv Rev , vol.2 , pp. 55-67
    • Allen, T.M.1
  • 3
    • 0018787411 scopus 로고
    • Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides
    • Baenziger JU, Fiete D. (1979). Structural determinants of Ricinus communis agglutinin and toxin specificity for oligosaccharides. J Biol Chem, 254, 9795-9799
    • (1979) J Biol Chem , vol.254 , pp. 9795-9799
    • Baenziger, J.U.1    Fiete, D.2
  • 4
    • 67349205002 scopus 로고    scopus 로고
    • Kupffer cells in non-alcoholic fatty liver disease: The emerging view
    • Baffy G. (2009). Kupffer cells in non-alcoholic fatty liver disease: the emerging view. J Hepatol, 51, 212-223
    • (2009) J Hepatol , vol.51 , pp. 212-223
    • Baffy, G.1
  • 5
    • 0033744850 scopus 로고    scopus 로고
    • Ultrastructural study of liver cell damage induced by ricin
    • Balint GA. (2000). Ultrastructural study of liver cell damage induced by ricin. Exp Toxicol Pathol, 52, 413-417
    • (2000) Exp Toxicol Pathol , vol.52 , pp. 413-417
    • Balint, G.A.1
  • 6
    • 0032943931 scopus 로고    scopus 로고
    • An in vivo model to study immunotoxin-induced vascular leak in human tissue
    • DOI 10.1097/00002371-199901000-00006
    • Baluna R, Vitetta ES. (1999). An in vivo model to study immunotoxininduced vascular leak in human tissue. J Immunother, 22, 41-47 (Pubitemid 29042289)
    • (1999) Journal of Immunotherapy , vol.22 , Issue.1 , pp. 41-47
    • Baluna, R.1    Vitetta, E.S.2
  • 7
    • 0030076357 scopus 로고    scopus 로고
    • Hepatotoxicity of ricin, saporin or a saporin immunotoxin: Xanthine oxidase activity in rat liver and blood serum
    • Battelli MG, Buonamici L, Polito L, Bolognesi A, Stirpe F. (1996). Hepatoxicity of ricin, saporin or a saporin immunotoxin: xanthine oxidase activity in rat liver and blood serum. Virchows Arch, 427, 529-535 (Pubitemid 126828185)
    • (1996) Virchows Archiv , vol.427 , Issue.5 , pp. 529-535
    • Battelli, M.G.1    Buonamici, L.2    Polito, L.3    Bologncsi, A.4    Stirpc, F.5
  • 8
    • 32844458032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it
    • Begriche K, Igoudjil A, Pessayre D, Fromenty B. (2006). Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion, 6, 1-28
    • (2006) Mitochondrion , vol.6 , pp. 1-28
    • Begriche, K.1    Igoudjil, A.2    Pessayre, D.3    Fromenty, B.4
  • 9
    • 0023202680 scopus 로고
    • The Kupffer cell is the first target in ricin-induced hepatitis
    • Bingen A, Creppy EE, Gut JP, Dirheimer G, Kirn A. (1987). The Kupffer cell is the first target in ricin-induced hepatitis. J Submicrosc Cytol, 19, 247-256 (Pubitemid 17083818)
    • (1987) Journal of Submicroscopic Cytology , vol.19 , Issue.2 , pp. 247-256
    • Bingen, A.1    Creppy, E.E.2    Gut, J.P.3
  • 10
    • 0024294244 scopus 로고
    • Uptake of native and deglycosylated ricin A-chain immunotoxins by mouse liver parenchymal and non-parenchymal cells in vitro and in vivo
    • Blakey DC, Skilleter DN, Price RJ, Thorpe PE. (1988). Uptake of native and deglycosylated ricin A-chain immunotoxins by mouse liver parenchymal and non-parenchymal cells in vitro and in vivo. Biochim Biophys Acta, 968, 172-178
    • (1988) Biochim Biophys Acta , vol.968 , pp. 172-178
    • Blakey, D.C.1    Skilleter, D.N.2    Price, R.J.3    Thorpe, P.E.4
  • 11
    • 0022531538 scopus 로고
    • Study of the plasma clearance of antibody - Ricin-A-chain immunotoxins. Evidence for specific recognition sites on the A chain that mediate rapid clearance of the immunotoxin
    • Bourrie BJ, Casellas P, Blythman HE, Jansen FK. (1986). Study of the plasma clearance of antibody-ricin-A-chain immunotoxins. Evidence for specific recognition sites on the A chain that mediate rapid clearance of the immunotoxin. Eur J Biochem, 155, 1-10 (Pubitemid 16077752)
    • (1986) European Journal of Biochemistry , vol.155 , Issue.1 , pp. 1-10
    • Bourrie, B.J.P.1    Casellas, P.2    Blythman, H.E.3    Jansen, F.K.4
  • 12
    • 0036829435 scopus 로고    scopus 로고
    • Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning
    • DOI 10.1016/S0891-5849(02)01017-1, PII S0891584902010171
    • Cutrn JC, Perrelli MG, Cavalieri B, Peralta C, Rosell Catafau J, Poli G. (2002). Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning. Free Radic Biol Med, 33, 1200-1208 (Pubitemid 35246588)
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.9 , pp. 1200-1208
    • Cutrn, J.C.1    Perrelli, M.-G.2    Cavalieri, B.3    Peralta, C.4    Rosell Catafau, J.5    Poli, G.6
  • 13
    • 2942530316 scopus 로고    scopus 로고
    • Ricin: Mechanism of toxicity, clinical manifestations, and vaccine development. A review
    • DOI 10.1081/CLT-120030945
    • Doan LG. (2004). Ricin: mechanism of toxicity, clinical manifestations, and vaccine development. A review. J Toxicol Clin Toxicol, 42, 201-208 (Pubitemid 38758534)
    • (2004) Journal of Toxicology - Clinical Toxicology , vol.42 , Issue.2 , pp. 201-208
    • Doan, L.G.1
  • 14
    • 0032556905 scopus 로고    scopus 로고
    • Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
    • DOI 10.1038/34923
    • Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B, van der Vliet A. (1998). Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature, 391, 393-397 (Pubitemid 28093514)
    • (1998) Nature , vol.391 , Issue.6665 , pp. 393-397
    • Eiserich, J.P.1    Hristova, M.2    Cross, C.E.3    Jones, A.D.4    Freeman, B.A.5    Halliwell, B.6    Van Der Vliet, A.7
  • 15
    • 35348860706 scopus 로고    scopus 로고
    • Ricin A chain from Ricinus sanguineus: DNA sequence, structure and toxicity
    • DOI 10.1007/s10930-007-9088-x
    • El-Nikhely N, Helmy M, Saeed HM, Abou Shama LA, Abd El-Rahman Z. (2007). Ricin A Chain from Ricinus sanguineus: DNA sequence, structure and toxicity. Protein J, 26, 481-489 (Pubitemid 47573260)
    • (2007) Protein Journal , vol.26 , Issue.7 , pp. 481-489
    • El-Nikhely, N.1    Helmy, M.2    Saeed, H.M.3    Abou Shama, L.A.4    Abd El-Rahman, Z.5
  • 16
    • 0027138758 scopus 로고
    • Endosomal proteolysis precedes ricin A-chain toxicity in macrophages
    • DOI 10.1006/abbi.1993.1583
    • Fiani ML, Blum JS, Stahl PD. (1993). Endosomal proteolysis precedes ricin A-chain toxicity in macrophages. Arch Biochem Biophys, 307, 225-230 (Pubitemid 24001556)
    • (1993) Archives of Biochemistry and Biophysics , vol.307 , Issue.2 , pp. 225-230
    • Fiani, M.L.1    Blum, J.S.2    Stahl, P.D.3
  • 17
    • 0031957118 scopus 로고    scopus 로고
    • Inhibition of LPS-mediated activation in rat Kupffer cells by N- acetylcysteine occurs subsequent to NF-κB translocation and requires protein synthesis
    • Fox ES, Leingang KA. (1998). Inhibition of LPS-mediated activation in rat Kupffer cells by N-acetylcysteine occurs subsequent to NF-kappaB translocation and requires protein synthesis. J Leukoc Biol, 63, 509-514 (Pubitemid 28163192)
    • (1998) Journal of Leukocyte Biology , vol.63 , Issue.4 , pp. 509-514
    • Fox, E.S.1    Leingang, K.A.2
  • 19
    • 0032608756 scopus 로고    scopus 로고
    • Time- and concentration-dependent production of superoxide anion, nitric oxide, DNA damage and cellular death by ricin in the J774A.1 macrophage cells
    • Hassoun EA, Wang X. (1999). Time- and concentration-dependent production of superoxide anion, nitric oxide, DNA damage and cellular death by ricin in the J774A.1 macrophage cells. J Biochem Mol Toxicol, 13, 179-185 (Pubitemid 129705390)
    • (1999) Journal of Biochemical and Molecular Toxicology , vol.13 , Issue.3-4 , pp. 179-185
    • Hassoun, E.A.1    Wang, X.2
  • 20
    • 10044237489 scopus 로고    scopus 로고
    • 1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride
    • DOI 10.1016/j.tox.2004.09.013, PII S0300483X04005670
    • He Q, Kim J, Sharma RP. (2005). Fumonisin B1 hepatotoxicity in mice is attenuated by depletion of Kupffer cells by gadolinium chloride. Toxicology, 207, 137-147 (Pubitemid 39601693)
    • (2005) Toxicology , vol.207 , Issue.1 , pp. 137-147
    • He, Q.1    Kim, J.2    Sharma, R.P.3
  • 21
    • 0032147208 scopus 로고    scopus 로고
    • Biological tyrosine nitration: A pathophysiological function of nitric oxide and reactive oxygen species
    • DOI 10.1006/abbi.1998.0755
    • Ischiropoulos H. (1998). Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys, 356, 1-11 (Pubitemid 28364347)
    • (1998) Archives of Biochemistry and Biophysics , vol.356 , Issue.1 , pp. 1-11
    • Ischiropoulos, H.1
  • 22
  • 23
    • 33748307666 scopus 로고    scopus 로고
    • Role of neutrophils in acute inflammatory liver injury
    • DOI 10.1111/j.1478-3231.2006.01327.x
    • Jaeschke H, Hasegawa T. (2006). Role of neutrophils in acute inflammatory liver injury. Liver Int, 26, 912-919 (Pubitemid 44323408)
    • (2006) Liver International , vol.26 , Issue.8 , pp. 912-919
    • Jaeschke, H.1    Hasegawa, T.2
  • 24
    • 0027933593 scopus 로고
    • Purification of cultured primary rat hepatocytes using selection with ricin A subunit
    • DOI 10.1016/0270-9139(94)90197-X
    • Johnston DE, Jasuja R. (1994). Purification of cultured primary rat hepatocytes using selection with ricin A subunit. Hepatology, 20, 436-444 (Pubitemid 24233372)
    • (1994) Hepatology , vol.20 , Issue.2 , pp. 436-444
    • Johnston, D.E.1    Jasuja, R.2
  • 25
    • 11144247941 scopus 로고    scopus 로고
    • Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and p38 MAPK and provides a mouse model of hemolytic uremic syndrome
    • Korcheva V, Wong J, Corless C, Iordanov M, Magun B. (2005). Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome. Am J Pathol, 166, 323-339 (Pubitemid 40051684)
    • (2005) American Journal of Pathology , vol.166 , Issue.1 , pp. 323-339
    • Korcheva, V.1    Wong, J.2    Corless, C.3    Iordanov, M.4    Magun, B.5
  • 26
    • 33846903334 scopus 로고    scopus 로고
    • Role of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophages
    • DOI 10.1016/j.molimm.2006.10.025, PII S0161589006006614
    • Korcheva V, Wong J, Lindauer M, Jacoby DB, Iordanov MS, Magun B. (2007). Role of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophages. Mol Immunol, 44, 2761-2771 (Pubitemid 46240306)
    • (2007) Molecular Immunology , vol.44 , Issue.10 , pp. 2761-2771
    • Korcheva, V.1    Wong, J.2    Lindauer, M.3    Jacoby, D.B.4    Iordanov, M.S.5    Magun, B.6
  • 28
    • 0037357016 scopus 로고    scopus 로고
    • Oxidative stress associated hepatic and renal toxicity induced by ricin in mice
    • DOI 10.1016/S0041-0101(02)00313-6, PII S0041010102003136
    • Kumar O, Sugendran K, Vijayaraghavan R. (2003). Oxidative stress associated hepatic and renal toxicity induced by ricin in mice. Toxicon, 41, 333-338 (Pubitemid 36144172)
    • (2003) Toxicon , vol.41 , Issue.3 , pp. 333-338
    • Kumar, O.1    Sugendran, K.2    Vijayaraghavan, R.3
  • 29
    • 0027292645 scopus 로고
    • Ricin induces the production of tumour necrosis factor-α and interleukin-1β by human peripheral-blood mononuclear cells
    • Licastro F, Morini MC, Bolognesi A, Stirpe F. (1993). Ricin induces the production of tumour necrosis factor-alpha and interleukin-1 beta by human peripheral-blood mononuclear cells. Biochem J, 294 (Pt 2), 517-520 (Pubitemid 23268855)
    • (1993) Biochemical Journal , vol.294 , Issue.2 , pp. 517-520
    • Licastro, F.1    Morini, M.C.2    Bolognesi, A.3    Stirpe, F.4
  • 31
    • 0027174451 scopus 로고
    • Endocytosis of ricin by rat liver cells in vivo and in vitro is mainly mediated by mannose receptors on sinusoidal endothelial cells
    • Magnsson S, Berg T. (1993). Endocytosis of ricin by rat liver cells in vivo and in vitro is mainly mediated by mannose receptors on sinusoidal endothelial cells. Biochem J, 291 (Pt 3), 749-755 (Pubitemid 23148448)
    • (1993) Biochemical Journal , vol.291 , Issue.3 , pp. 749-755
    • Magnusson, S.1    Berg, T.2
  • 32
    • 0027160323 scopus 로고
    • Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells
    • DOI 10.1006/excr.1993.1065
    • Magnusson S, Kjeken R, Berg T. (1993). Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells. Exp Cell Res, 205, 118-125 (Pubitemid 23192110)
    • (1993) Experimental Cell Research , vol.205 , Issue.1 , pp. 118-125
    • Magnusson, S.1    Kjeken, R.2    Berg, T.3
  • 34
    • 51649091581 scopus 로고    scopus 로고
    • Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents
    • Mitsopoulos P, Omri A, Alipour M, Vermeulen N, Smith MG, Suntres ZE. (2008). Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. Int J Pharm, 363, 106-111
    • (2008) Int J Pharm , vol.363 , pp. 106-111
    • Mitsopoulos, P.1    Omri, A.2    Alipour, M.3    Vermeulen, N.4    Smith, M.G.5    Suntres, Z.E.6
  • 35
    • 78149465001 scopus 로고    scopus 로고
    • Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat
    • Mitsopoulos P, Suntres ZE. (2010). Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat. Chem Biol Interact, 188, 427-436
    • (2010) Chem Biol Interact , vol.188 , pp. 427-436
    • Mitsopoulos, P.1    Suntres, Z.E.2
  • 36
    • 0026667633 scopus 로고
    • Ricin-induced hepatic lipid peroxidation, glutathione depletion, and DNA single-strand breaks in mice
    • Muldoon DF, Hassoun EA, Stohs SJ. (1992). Ricin-induced hepatic lipid peroxidation, glutathione depletion, and DNA single-strand breaks in mice. Toxicon, 30, 977-984
    • (1992) Toxicon , vol.30 , pp. 977-984
    • Muldoon, D.F.1    Hassoun, E.A.2    Stohs, S.J.3
  • 37
    • 0028354394 scopus 로고
    • Modulation of ricin toxicity in mice by biologically active substances
    • Muldoon DF, Stohs SJ. (1994). Modulation of ricin toxicity in mice by biologically active substances. J Appl Toxicol, 14, 81-86 (Pubitemid 24124981)
    • (1994) Journal of Applied Toxicology , vol.14 , Issue.2 , pp. 81-86
    • Muldoon, D.F.1    Stohs, S.J.2
  • 38
    • 0030474051 scopus 로고    scopus 로고
    • Thiol regulation of endotoxin-induced release of tumour necrosis factor α from isolated rat Kupffer cells
    • Neuschwander-Tetri BA, Bellezzo JM, Britton RS, Bacon BR, Fox ES. (1996). Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells. Biochem J, 320 (Pt 3), 1005-1010 (Pubitemid 27013820)
    • (1996) Biochemical Journal , vol.320 , Issue.3 , pp. 1005-1010
    • Neuschwander-Tetri, B.A.1    Bellezzo, J.M.2    Britton, R.S.3    Bacon, B.R.4    Fox, E.S.5
  • 40
    • 7044249860 scopus 로고    scopus 로고
    • Determination of the thiol redox state of organisms: New oxidative stress indicators
    • DOI 10.1007/s00216-004-2525-1
    • Patsoukis N, Georgiou CD. (2004). Determination of the thiol redox state of organisms: new oxidative stress indicators. Anal Bioanal Chem, 378, 1783-1792 (Pubitemid 40877658)
    • (2004) Analytical and Bioanalytical Chemistry , vol.378 , Issue.7 , pp. 1783-1792
    • Patsoukis, N.1    Georgiou, C.D.2
  • 41
    • 33750564770 scopus 로고    scopus 로고
    • Reactions of myeloperoxidase-derived oxidants with biological substrates: Gaining chemical insight into human inflammatory diseases
    • DOI 10.2174/092986706778773095
    • Pattison DI, Davies MJ. (2006). Reactions of myeloperoxidase-derived oxidants with biological substrates: gaining chemical insight into human inflammatory diseases. Curr Med Chem, 13, 3271-3290 (Pubitemid 44669775)
    • (2006) Current Medicinal Chemistry , vol.13 , Issue.27 , pp. 3271-3290
    • Pattison, D.I.1    Davies, M.J.2
  • 42
    • 4444317796 scopus 로고    scopus 로고
    • Antitoxins: Novel strategies to target agents of bioterrorism
    • DOI 10.1038/nrmicro977
    • Rainey GJ, Young JA. (2004). Antitoxins: novel strategies to target agents of bioterrorism. Nat Rev Microbiol, 2, 721-726 (Pubitemid 39200063)
    • (2004) Nature Reviews Microbiology , vol.2 , Issue.9 , pp. 721-726
    • Rainey, G.J.A.1    Young, J.A.T.2
  • 43
    • 0024592576 scopus 로고
    • The toxicity, distribution and excretion of ricin holotixin in rats
    • DOI 10.1016/0300-483X(89)90183-2
    • Ramsden CS, Drayson MT, Bell EB. (1989). The toxicity, distribution and excretion of ricin holotoxin in rats. Toxicology, 55, 161-171 (Pubitemid 19094987)
    • (1989) Toxicology , vol.55 , Issue.1-2 , pp. 161-171
    • Ramsden, C.S.1    Drayson, M.T.2    Bell, E.B.3
  • 44
    • 33745600868 scopus 로고    scopus 로고
    • Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective
    • DOI 10.1016/j.jconrel.2006.04.015, PII S0168365906002057
    • Ratnam DV, Ankola DD, Bhardwaj V, Sahana DK, Kumar MN. (2006). Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective. J Control Release, 113, 189-207 (Pubitemid 43983041)
    • (2006) Journal of Controlled Release , vol.113 , Issue.3 , pp. 189-207
    • Ratnam, D.V.1    Ankola, D.D.2    Bhardwaj, V.3    Sahana, D.K.4    Kumar, M.N.V.R.5
  • 46
    • 54949121317 scopus 로고    scopus 로고
    • Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model
    • Roche JK, Stone MK, Gross LK, Lindner M, Seaner R, Pincus SH, Obrig TG. (2008). Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model. Lab Invest, 88, 1178-1191
    • (2008) Lab Invest , vol.88 , pp. 1178-1191
    • Roche, J.K.1    Stone, M.K.2    Gross, L.K.3    Lindner, M.4    Seaner, R.5    Pincus, S.H.6    Obrig, T.G.7
  • 47
    • 77953127589 scopus 로고    scopus 로고
    • Protein toxins from plants and bacteria: Probes for intracellular transport and tools in medicine
    • Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG. (2010). Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine. FEBS Lett, 584, 2626-2634
    • (2010) FEBS Lett , vol.584 , pp. 2626-2634
    • Sandvig, K.1    Torgersen, M.L.2    Engedal, N.3    Skotland, T.4    Iversen, T.G.5
  • 48
    • 70349429612 scopus 로고    scopus 로고
    • Ricin as a weapon of mass terror-separating fact from fiction
    • Schep LJ, Temple WA, Butt GA, Beasley MD. (2009). Ricin as a weapon of mass terror-separating fact from fiction. Environ Int, 35, 1267-1271
    • (2009) Environ Int , vol.35 , pp. 1267-1271
    • Schep, L.J.1    Temple, W.A.2    Butt, G.A.3    Beasley, M.D.4
  • 49
    • 0035102917 scopus 로고    scopus 로고
    • The role of hepatocytes in the clearance of liposomes from the blood circulation
    • DOI 10.1016/S0163-7827(00)00020-5, PII S0163782700000205
    • Scherphof GL, Kamps JA. (2001). The role of hepatocytes in the clearance of liposomes from the blood circulation. Prog Lipid Res, 40, 149-166 (Pubitemid 32220186)
    • (2001) Progress in Lipid Research , vol.40 , Issue.3 , pp. 149-166
    • Scherphof, G.L.1    Kamps, J.A.A.M.2
  • 51
    • 77952955444 scopus 로고    scopus 로고
    • Different in vitro toxicities of structurally similar type i ribosome-inactivating proteins (RIPs)
    • Sha O, Yew DT, Ng TB, Yuan L, Kwong WH. (2010). Different in vitro toxicities of structurally similar type I ribosome-inactivating proteins (RIPs). Toxicol In Vitro, 24, 1176-1182
    • (2010) Toxicol in Vitro , vol.24 , pp. 1176-1182
    • Sha, O.1    Yew, D.T.2    Ng, T.B.3    Yuan, L.4    Kwong, W.H.5
  • 52
    • 0023669219 scopus 로고
    • In vivo depletion of mannose receptor bearing cells from rat liver by ricin A chain: Effects on clearance of beta-glucuronidase
    • Simmons BM, Stahl PD, Russell JH. (1987). In vivo depletion of mannose receptor bearing cells from rat liver by ricin A chain: effects on clearance of beta-glucuronidase. Biochem Biophys Res Commun, 146, 849-854
    • (1987) Biochem Biophys Res Commun , vol.146 , pp. 849-854
    • Simmons, B.M.1    Stahl, P.D.2    Russell, J.H.3
  • 53
    • 0022552817 scopus 로고
    • Selective uptake of ricin A-chain by hepatic nonparenchymal cells in vitro. Importance of mannose oligosaccharides in the toxin
    • DOI 10.1016/0014-5793(86)80276-9
    • Skilleter DN, Foxwell BM. (1986). Selective uptake of ricin A-chain by hepatic non-parenchymal cells in vitro. Importance of mannose oligosaccharides in the toxin. FEBS Lett, 196, 344-348 (Pubitemid 16047489)
    • (1986) FEBS Letters , vol.196 , Issue.2 , pp. 344-348
    • Skilleter, D.N.1    Foxwell, B.M.J.2
  • 54
    • 0019869796 scopus 로고
    • A comparison of the accumulation of ricin by hepatic parenchymal and non-parenchymal cells and its inhibition of protein synthesis
    • Skilleter DN, Paine AJ, Stirpe F. (1981). A comparison of the accumulation of ricin by hepatic parenchymal and nonparenchymal cells and its inhibition of protein synthesis. Biochim Biophys Acta, 677, 495-500 (Pubitemid 12207077)
    • (1981) Biochimica et Biophysica Acta , vol.677 , Issue.3-4 , pp. 495-500
    • Skilleter, D.N.1    Paine, A.J.2    Stirpe, F.3
  • 55
    • 4043133131 scopus 로고    scopus 로고
    • Ribosome-inactivating proteins
    • DOI 10.1016/j.toxicon.2004.05.004, PII S0041010104001904
    • Stirpe F. (2004). Ribosome-inactivating proteins. Toxicon, 44, 371-383 (Pubitemid 39070639)
    • (2004) Toxicon , vol.44 , Issue.4 , pp. 371-383
    • Stirpe, F.1
  • 57
    • 0037201949 scopus 로고    scopus 로고
    • Role of antioxidants in paraquat toxicity
    • DOI 10.1016/S0300-483X(02)00382-7, PII S0300483X02003827
    • Suntres ZE. (2002). Role of antioxidants in paraquat toxicity. Toxicology, 180, 65-77 (Pubitemid 35248093)
    • (2002) Toxicology , vol.180 , Issue.1 , pp. 65-77
    • Suntres, Z.E.1
  • 58
    • 0026457784 scopus 로고
    • Protective effect of liposome-associated alpha-tocopherol against paraquat-induced acute lung toxicity
    • Suntres ZE, Hepworth SR, Shek PN. (1992). Protective effect of liposome-associated alpha-tocopherol against paraquat-induced acute lung toxicity. Biochem Pharmacol, 44, 1811-1818
    • (1992) Biochem Pharmacol , vol.44 , pp. 1811-1818
    • Suntres, Z.E.1    Hepworth, S.R.2    Shek, P.N.3
  • 59
    • 0029682892 scopus 로고    scopus 로고
    • Treatment of LPS-induced tissue injury: Role of liposomal antioxidants
    • Suntres ZE, Shek PN. (1996). Treatment of LPS-induced tissue injury: role of liposomal antioxidants. Shock, 6 Suppl 1, S57-S64 (Pubitemid 126727797)
    • (1996) Shock , vol.6 , Issue.6 SUPPL.
    • Suntres, Z.E.1    Shek, P.N.2
  • 60
    • 0031920110 scopus 로고    scopus 로고
    • Prophylaxis against lipopolysaccharide-induced acute lung injury by α- tocopherol liposomes
    • DOI 10.1097/00003246-199804000-00023
    • Suntres ZE, Shek PN. (1998). Prophylaxis against lipopolysaccharideinduced acute lung injury by alpha-tocopherol liposomes. Crit Care Med, 26, 723-729 (Pubitemid 28201420)
    • (1998) Critical Care Medicine , vol.26 , Issue.4 , pp. 723-729
    • Suntres, Z.E.1    Shek, P.N.2
  • 61
    • 0033969395 scopus 로고    scopus 로고
    • Prophylaxis against lipopolysaccharide-induced lung injuries by liposome-entrapped dexamethasone in rats
    • DOI 10.1016/S0006-2952(99)00411-6, PII S0006295299004116
    • Suntres ZE, Shek PN. (2000). Prophylaxis against lipopolysaccharideinduced lung injuries by liposome-entrapped dexamethasone in rats. Biochem Pharmacol, 59, 1155-1161 (Pubitemid 30110509)
    • (2000) Biochemical Pharmacology , vol.59 , Issue.9 , pp. 1155-1161
    • Suntres, Z.E.1    Shek, P.N.2
  • 62
    • 35348872878 scopus 로고    scopus 로고
    • Ricin-Induced Tissue Toxicity: The Role of Oxidative Stress
    • Suntres ZE, Stone WL, Smith MG. (2005). Ricin-Induced Tissue Toxicity: The Role of Oxidative Stress. J Med CBR Def 3
    • (2005) J Med CBR Def , pp. 3
    • Suntres, Z.E.1    Stone, W.L.2    Smith, M.G.3
  • 63
    • 0022425552 scopus 로고
    • Modification of the carbohydrate in ricin with metaperiodate- cyanoborohydride mixtures. Effects on toxicity and in vivo distribution
    • Thorpe PE, Detre SI, Foxwell BM, Brown AN, Skilleter DN, Wilson G, Forrester JA, Stirpe F. (1985). Modification of the carbohydrate in ricin with metaperiodate-cyanoborohydride mixtures. Effects on toxicity and in vivo distribution. Eur J Biochem, 147, 197-206
    • (1985) Eur J Biochem , vol.147 , pp. 197-206
    • Thorpe, P.E.1    Detre, S.I.2    Foxwell, B.M.3    Brown, A.N.4    Skilleter, D.N.5    Wilson, G.6    Forrester, J.A.7    Stirpe, F.8
  • 65
    • 33846860816 scopus 로고    scopus 로고
    • Future of toxicology - Lipid peroxidation in the future: From biomarker to etiology
    • DOI 10.1021/tx600304n
    • Uchida K. (2007). Future of toxicology-lipid peroxidation in the future: from biomarker to etiology. Chem Res Toxicol, 20, 3-5. (Pubitemid 46220148)
    • (2007) Chemical Research in Toxicology , vol.20 , Issue.1 , pp. 3-5
    • Uchida, K.1
  • 66
    • 33947123224 scopus 로고    scopus 로고
    • The antioxidant tempamine: In vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release
    • DOI 10.1021/la060218k
    • Wasserman V, Kizelsztein P, Garbuzenko O, Kohen R, Ovadia H, Tabakman R, Barenholz Y. (2007). The antioxidant tempamine: in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release. Langmuir, 23, 1937-1947 (Pubitemid 46406145)
    • (2007) Langmuir , vol.23 , Issue.4 , pp. 1937-1947
    • Wasserman, V.1    Kizelsztein, P.2    Garbuzenko, O.3    Kohen, R.4    Ovadia, H.5    Tabakman, R.6    Barenholz, Y.7
  • 67
    • 0029835057 scopus 로고    scopus 로고
    • The synovial membrane, liver, and tongue: Target organs for a ricin A- chain immunotoxin (ZD0490)
    • Westwood FR, Jones DV, Aldridge A. (1996). The synovial membrane, liver, and tongue: target organs for a ricin A-chain immunotoxin (ZD0490). Toxicol Pathol, 24, 477-483 (Pubitemid 26274857)
    • (1996) Toxicologic Pathology , vol.24 , Issue.4 , pp. 477-483
    • Westwood, F.R.1    Jones, D.V.2    Aldridge, A.3
  • 68
    • 3042697876 scopus 로고    scopus 로고
    • Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice
    • DOI 10.1002/hep.20288
    • Wu J, Liu L, Yen RD, Catana A, Nantz MH, Zern MA. (2004). Liposomemediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice. Hepatology, 40, 195-204 (Pubitemid 38868938)
    • (2004) Hepatology , vol.40 , Issue.1 , pp. 195-204
    • Wu, J.1    Liu, L.2    Yen, R.D.3    Catana, A.4    Nantz, M.H.5    Zern, M.A.6
  • 69
    • 0036518616 scopus 로고    scopus 로고
    • Targeting hepatocytes for drug and gene delivery: Emerging novel approaches and applications
    • Wu J, Nantz MH, Zern MA. (2002). Targeting hepatocytes for drug and gene delivery: emerging novel approaches and applications. Front Biosci, 7, d717-d725
    • (2002) Front Biosci , vol.7
    • Wu, J.1    Nantz, M.H.2    Ma, Z.3


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