Measures of anxiety, amygdala volumes, and hippocampal scopolamine phMRI response in elderly female rhesus macaques

Neuropharmacology

Volumn 62, Issue 1, 2012, Pages 385-390

  Haley, Gwendolen E ^a,b   McGuire, Acacia ^a   Berteau Pavy, Daphnee ^a   Weiss, Alison ^b   Patel, Roshni ^a   Messaoudi, Ilhem ^b   Urbanski, Henryk F ^a,b,c   Raber, Jacob ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Amygdala; Anxiety; Hippocampus; Nonhuman primate; phMRI; Scopolamine

Indexed keywords

MUSCARINIC RECEPTOR; SCOPOLAMINE;

AMYGDALA SIZE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANXIETY; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; FEMALE; HIPPOCAMPAL SIZE; HIPPOCAMPUS; MAZE TEST; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RHESUS MONKEY; TASK PERFORMANCE; TEMPERAMENT; VOXEL BASED MORPHOMETRY;

AGING; AMYGDALA; ANALYSIS OF VARIANCE; ANIMALS; ANXIETY; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEMALE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MAZE LEARNING; MUSCARINIC ANTAGONISTS; SCOPOLAMINE HYDROBROMIDE;

EID: 80054098145     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.08.014     Document Type: Conference Paper

References (56)

1. T. Ali-Melkkila, J. Kanto, and E. Iisalo Pharmacokinetics and related pharmacodynamics of anticholinergic drugs Acta Anaesthesiol. Scand. 37 1993 633 642 (Pubitemid 23298996)
2. D.G. Amaral, M.D. Bauman, and C.M. Schumann The amygdala and autism: implications from non-human primate studies Genes Brain Behav. 2 2003 295 302 (Pubitemid 37345667)
3. D.G. Amaral The amygdala, social behavior, and danger detection Ann. N. Y Acad. Sci. 1000 2003 337 347 (Pubitemid 38264850)
4. M. Barros, M. Giorgetti, A.A. Souto, G. Vilela, K. Santos, N.V. Boas, and C. Tomaz Persistent anxiety-like behavior in marmosets following a recent predatory stress condition: reversal by diazepam Pharmacol. Biochem. Behav. 86 2007 705 711 (Pubitemid 46829325)
5. M. Barros, R.S. Maior, J.P. Huston, and C. Tomaz Predatory stress as an experimental strategy to measure fear and anxiety-related behaviors in non-human primates Rev. Neurosci. 19 2008 157 169
6. J.G. Beck Cognitive aspects of anxiety and depression in the elderly Curr. Psychiatry Rep. 7 2005 27 31 (Pubitemid 40485476)
7. M. Bodnar, A.K. Malla, Y. Czechowska, A. Benoit, F. Fathalli, R. Joober, M. Pruessner, J. Pruessner, and M. Lepage Neural markers of remission in first-episode schizophrenia: a volumetric neuroimaging study of the hippocampus and amygdala Schizophr Res. 122 2010 72 80
8. P. Cagni, I. Goncalves Jr., F. Ziller, N. Emile, and M. Barros Humans and natural predators induce different fear/anxiety reactions and response pattern to diazepam in marmoset monkeys Pharmacol. Biochem. Behav. 93 2009 134 140
9. N.S. Canteras, L.B. Resstel, L.J. Bertoglio, P. Carobrez Ade, and F.S. Guimaraes Neuroanatomy of anxiety Curr. Top. Behav. Neurosci. 2 2010 77 96
10. A.E. Castaneda, A. Tuulio-Henriksson, M. Marttunen, J. Suvisaari, and J. Lonnqvist A review on cognitive impairments in depressive and anxiety disorders with a focus on young adults J. Affect Disord. 106 2008 1 27 (Pubitemid 350309672)
11. B.T. Christian, A.S. Fox, J.A. Oler, N.T. Vandehey, D. Murali, J. Rogers, T.R. Oakes, S.E. Shelton, R.J. Davidson, and N.H. Kalin Serotonin transporter binding and genotype in the nonhuman primate brain using [C-11]DASB PET Neuroimage 47 2009 1230 1236
12. K. Coleman, R.E. Dahl, N.D. Ryan, and J.L. Cameron Growth hormone response to growth hormone-releasing hormone and clonidine in young monkeys: correlation with behavioral characteristics J. Child. Adolesc. Psychopharmacol. 13 2003 227 241 (Pubitemid 37288523)
13. O.S. Davis, C.M. Haworth, and R. Plomin Dramatic increase in heritability of cognitive development from early to middle childhood: an 8-year longitudinal study of 8,700 pairs of twins Psychol. Sci. 20 2009 1301 1308
14. A. Degroot, and G.G. Nomikos Genetic deletion of muscarinic M4 receptors is anxiolytic in the shock-probe burying model Eur. J. Pharmacol. 531 2006 183 186 (Pubitemid 43202233)
15. L.A. Fairbanks, M.J. Jorgensen, A. Huff, K. Blau, Y.Y. Hung, and J.J. Mann Adolescent impulsivity predicts adult dominance attainment in male vervet monkeys Am. J. Primatol 64 2004 1 17 (Pubitemid 39428846)
16. L.A. Fairbanks, T.K. Newman, J.N. Bailey, M.J. Jorgensen, S.E. Breidenthal, R.A. Ophoff, A.G. Comuzzie, L.J. Martin, and J. Rogers Genetic contributions to social impulsivity and aggressiveness in vervet monkeys Biol. Psychiatry 55 2004 642 647 (Pubitemid 38315039)
17. M.L. Furey, A. Khanna, E.M. Hoffman, and W.C. Drevets Scopolamine produces larger antidepressant and antianxiety effects in women than in men Neuropsychopharmacology 35 2010 2479 2488
18. S. Gold, B. Christian, S. Arndt, G. Zeien, T. Cizadlo, D.L. Johnson, M. Flaum, and N.C. Andreasen Functional MRI statistical software packages: a comparative analysis Hum. Brain Mapp. 6 1998 73 84 (Pubitemid 28146507)
19. G.E. Haley, N. Landauer, L. Renner, A. Weiss, K. Hooper, H.F. Urbanski, S.G. Kohama, M. Neuringer, and J. Raber Circadian activity associated with spatial learning and memory in aging rhesus monkeys Exper Neurol. 217 2009 55 62
20. Haley, G.E., Kroenke, C., Schwarz, D., Kohama, S., Urbanski, H.F., Raber, J. Hippocampal M1 receptor function associated with spatial learning and memory in aged female rhesus macaques. Age, in press.
21. A.R. Hariri, V.S. Mattay, A. Tessitore, B. Kolachana, F. Fera, D. Goldman, M.F. Egan, and D.R. Weinberger Serotonin transporter genetic variation and the response of the human amygdala Science 297 2002 400 403 (Pubitemid 34790769)
22. E. Irle, C. Lange, U. Sachsse, and G. Weniger Further evidence that post-traumatic stress disorder but not dissociative disorders are related to amygdala and hippocampal size reduction in trauma-exposed individuals Acta Psychiatr. Scand. 119 2009 330 331 discussion 331
23. J.C. Jackson, N. Mitchell, and R.O. Hopkins Cognitive functioning, mental health, and quality of life in ICU survivors: an overview Crit. Care Clin. 25 2009 615 628 x
24. D. Janeway An integrated approach to the diagnosis and treatment of anxiety within the practice of cardiology Cardiol. Rev. 17 2009 36 43
25. N.H. Kalin, and S.E. Shelton Defensive behaviors in infant rhesus monkeys: environmental cues and neurochemical regulation Science 243 1989 1718 1721 (Pubitemid 19106969)
26. N.H. Kalin, S.E. Shelton, and L.K. Takahashi Defensive behaviors in infant rhesus monkeys: ontogeny and context-dependent selective expression Child. Dev. 62 1991 1175 1183
27. N.H. Kalin, S.E. Shelton, and R.J. Davidson The role of the central nucleus of the amygdala in mediating fear and anxiety in the primate J. Neurosci. 24 2004 5506 5515 (Pubitemid 38812633)
28. J.W. Kenney, D.S. Wilkinson, and T.J. Gould The enhancement of contextual fear conditioning by ABT-418 Behav. Pharmacol. 21 2010 246 249
29. F. Laplante, O. Nakagawasai, L.K. Srivastava, and R. Quirion Alterations in behavioral responses to a cholinergic agonist in post-pubertal rats with neonatal ventral hippocampal lesions: relationship to changes in muscarinic receptor levels Neuropsychopharmacology 30 2005 1076 1087 (Pubitemid 40720965)
30. K.P. Lesch, D. Bengel, A. Heils, S.Z. Sabol, B.D. Greenberg, S. Petri, J. Benjamin, C.R. Muller, D.H. Hamer, and D.L. Murphy Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1996 1527 1531 (Pubitemid 26403928)
31. K.P. Lesch Molecular foundation of anxiety disorders J. Neural Transm. 108 2001 717 746
32. C.J. Machado, and J. Bachevalier Behavioral and hormonal reactivity to threat: effects of selective amygdala, hippocampal or orbital frontal lesions in monkeys Psychoneuroendocrinology 33 2008 926 941
33. M. Maizels, T.A. Smitherman, and D.B. Penzien A review of screening tools for psychiatric comorbidity in headache patients Headache 46 Suppl. 3 2006 S98 S109
34. S.B. McHugh, R.M. Deacon, J.N. Rawlins, and D.M. Bannerman Amygdala and ventral hippocampus contribute differentially to mechanisms of fear and anxiety Behav. Neurosci. 118 2004 63 78 (Pubitemid 38222524)
35. J. Menard, and D. Treit Effects of centrally administered anxiolytic compounds in animal models of anxiety Neurosci. Biobehav Rev. 23 1999 591 613 (Pubitemid 29086927)
36. Y.S. Mineur, O. Somenzi, and M.R. Picciotto Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice Neuropharmacology 52 2007 1256 1262 (Pubitemid 46527701)
37. M.R. Munafo, S.M. Brown, and A.R. Hariri Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis Biol. Psychiatry 63 2008 852 857 (Pubitemid 351458448)
38. J.D. Newman, and M.J. Farley An ethologically based, stimulus and gender-sensitive nonhuman primate model for anxiety Prog. Neuropsychopharmacol. Biol. Psychiatry 19 1995 677 685
39. J.A. Oler, A.S. Fox, S.E. Shelton, J. Rogers, T.D. Dyer, R.J. Davidson, W. Shelledy, T.R. Oakes, J. Blangero, and N.H. Kalin Amygdalar and hippocampal substrates of anxious temperament differ in their heritability Nature 466 2010 864 868
40. K.J. Parker, C.L. Buckmaster, A.F. Schatzberg, and D.M. Lyons Prospective investigation of stress inoculation in young monkeys Arch. Gen. Psychiatry 61 2004 933 941 (Pubitemid 39181083)
41. H. Rao, S.J. Gillihan, J. Wang, M. Korczykowski, G.M. Sankoorikal, K.A. Kaercher, E.S. Brodkin, J.A. Detre, and M.J. Farah Genetic variation in serotonin transporter alters resting brain function in healthy individuals Biol. Psychiatry 62 2007 600 606 (Pubitemid 47314381)
42. A.J. Shackman, I. Sarinopoulos, J.S. Maxwell, D.A. Pizzagalli, A. Lavric, and R.J. Davidson Anxiety selectively disrupts visuospatial working memory Emotion 6 2006 40 61 (Pubitemid 43829895)
43. Siegel, J.A., Haley, G.E., Raber, J. Apolipoprotein E isoform-dependent effects on anxiety and cognition in female TR mice. Neurobiol Aging, in press.
44. S.A. Small, M.K. Chawla, M. Buonocore, P.R. Rapp, and C.A. Barnes Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging Proc. Natl. Acad. Sci. U. S. A. 101 2004 7181 7186 (Pubitemid 38596463)
45. R.C. Smith, and C.D. Lay State and trait anxiety: an annotated bibliography Psychol. Rep. 34 1974 519 594
46. J.W. Smythe, S. Bhatnagar, D. Murphy, C. Timothy, and B. Costall The effects of intrahippocampal scopolamine infusions on anxiety in rats as measured by the black-white box test Brain Res. Bull. 45 1998 89 93 (Pubitemid 28048773)
47. E.L. Sullivan, B. Grayson, D. Takahashi, N. Robertson, A. Maier, C.L. Bethea, M.S. Smith, K. Coleman, and K.L. Grove Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring J. Neurosci. 30 2010 3826 3830
48. P. Vicens, D. Ribes, M. Torrente, and J.L. Domingo Behavioral effects of PNU-282987, an alpha7 nicotinic receptor agonist, in mice Behav. Brain Res. 216 2011 341 348
49. C.H. Vinkers, E.Y. Bijlsma, L.C. Houtepen, K.G. Westphal, J.G. Veening, L. Groenink, and B. Olivier Medial amygdala lesions differentially influence stress responsivity and sensorimotor gating in rats Physiol. Behav. 99 2010 395 401
50. P.M. Visscher, W.G. Hill, and N.R. Wray Heritability in the genomics era - concepts and misconceptions Nat. Rev. Genet. 9 2008 255 266 (Pubitemid 351399832)
51. P.M. Wall, J. Flinn, and C. Messier Infralimbic muscarinic M1 receptors modulate anxiety-like behaviour and spontaneous working memory in mice Psychopharmacology (Berl) 155 2001 58 68 (Pubitemid 32295770)
52. G. Weniger, C. Lange, U. Sachsse, and E. Irle Amygdala and hippocampal volumes and cognition in adult survivors of childhood abuse with dissociative disorders Acta Psychiatr. Scand. 118 2008 281 290
53. G. Weniger, C. Lange, U. Sachsse, and E. Irle Reduced amygdala and hippocampus size in trauma-exposed women with borderline personality disorder and without posttraumatic stress disorder J. Psychiatry Neurosci. 34 2009 383 388
54. S.H. Woodward, D.G. Kaloupek, C.C. Streeter, C. Martinez, M. Schaer, and S. Eliez Decreased anterior cingulate volume in combat-related PTSD Biol. Psychiatry 59 2006 582 587 (Pubitemid 43357951)
55. J. Wrase, M. Reimold, I. Puls, T. Kienast, and A. Heinz Serotonergic dysfunction: brain imaging and behavioral correlates Cogn. Affect Behav. Neurosci. 6 2006 53 61
56. Z. Zhou, G. Zhu, A.R. Hariri, M.A. Enoch, D. Scott, R. Sinha, M. Virkkunen, D.C. Mash, R.H. Lipsky, X.Z. Hu, C.A. Hodgkinson, K. Xu, B. Buzas, Q. Yuan, P.H. Shen, R.E. Ferrell, S.B. Manuck, S.M. Brown, R.L. Hauger, C.S. Stohler, J.K. Zubieta, and D. Goldman Genetic variation in human NPY expression affects stress response and emotion Nature 452 2008 997 1001 (Pubitemid 351589618)