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Volumn 35, Issue 12, 2010, Pages 2479-2488

Scopolamine produces larger antidepressant and antianxiety effects in women than in men

Author keywords

anticholinergic; antidepressant; antimuscarinic; depression; gender

Indexed keywords

PLACEBO; SCOPOLAMINE;

EID: 77958001705     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.131     Document Type: Article
Times cited : (105)

References (55)
  • 3
    • 0031962557 scopus 로고    scopus 로고
    • The influence of age and sex on the prevalence of depressive conditions: Report from the National Survey of Psychiatric Morbidity
    • Bebbington PE, Dunn G, Jenkins R, Lewis G, Brugha T, Farrell M et al (1998). The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity. Psychol Med 28: 9-19.
    • (1998) Psychol Med , vol.28 , pp. 9-19
    • Bebbington, P.E.1    Dunn, G.2    Jenkins, R.3    Lewis, G.4    Brugha, T.5    Farrell, M.6
  • 4
    • 58149463233 scopus 로고    scopus 로고
    • Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine
    • Benmansour S, Piotrowski JP, Altamirano AV, Frazer A (2009). Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine. Neuropsychopharmacology 34: 555-564.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 555-564
    • Benmansour, S.1    Piotrowski, J.P.2    Altamirano, A.V.3    Frazer, A.4
  • 5
    • 33846190717 scopus 로고    scopus 로고
    • Different gender response to serotonergic and noradrenergic antidepressants. A comparative study of the efficacy of citalopram and reboxetine
    • Berlanga C, Flores-Ramos M (2006). Different gender response to serotonergic and noradrenergic antidepressants. A comparative study of the efficacy of citalopram and reboxetine. J Affect Disord 95: 119-123.
    • (2006) J Affect Disord , vol.95 , pp. 119-123
    • Berlanga, C.1    Flores-Ramos, M.2
  • 6
    • 0023919025 scopus 로고
    • Lifetime prevalence of psychiatric disorders in Edmonton
    • Bland RC, Orn H, Newman SC (1988). Lifetime prevalence of psychiatric disorders in Edmonton. Acta Psychiatr Scand Suppl 338: 24-32.
    • (1988) Acta Psychiatr Scand Suppl , vol.338 , pp. 24-32
    • Bland, R.C.1    Orn, H.2    Newman, S.C.3
  • 8
    • 0037043027 scopus 로고    scopus 로고
    • Association of the muscarinic cholinergic 2 receptor (CHRM2) gene with major depression in women
    • Comings DE, Wu S, Rostamkhani M, McGue M, Iacono WG, MacMurray JP (2002). Association of the muscarinic cholinergic 2 receptor (CHRM2) gene with major depression in women. Am J Med Genet 114: 527-529.
    • (2002) Am J Med Genet , vol.114 , pp. 527-529
    • Comings, D.E.1    Wu, S.2    Rostamkhani, M.3    McGue, M.4    Iacono, W.G.5    MacMurray, J.P.6
  • 9
    • 0035449911 scopus 로고    scopus 로고
    • Acetylcholine mediates the estrogen-induced increase in NMDA receptor binding in CA1 of the hippocampus and the associated improvement in working memory
    • Daniel JM, Dohanich GP (2001). Acetylcholine mediates the estrogen-induced increase in NMDA receptor binding in CA1 of the hippocampus and the associated improvement in working memory. J Neurosci 21: 6949-6956.
    • (2001) J Neurosci , vol.21 , pp. 6949-6956
    • Daniel, J.M.1    Dohanich, G.P.2
  • 10
    • 0024578607 scopus 로고
    • Progesterone effects upon dopamine release from the corpus striatum of female rats. I. Evidence for interneuronal control
    • Dluzen DE, Ramirez VD (1989). Progesterone effects upon dopamine release from the corpus striatum of female rats. I. Evidence for interneuronal control. Brain Res 476: 332-337.
    • (1989) Brain Res , vol.476 , pp. 332-337
    • Dluzen, D.E.1    Ramirez, V.D.2
  • 11
    • 75849117116 scopus 로고    scopus 로고
    • Replication of scopolamine's antidepressant efficacy in major depressive disorder: A randomized, placebo-controlled clinical trial
    • Drevets WC, Furey ML (2010). Replication of scopolamine's antidepressant efficacy in major depressive disorder: a randomized, placebo-controlled clinical trial. Biol Psychiatry 67: 432-438.
    • (2010) Biol Psychiatry , vol.67 , pp. 432-438
    • Drevets, W.C.1    Furey, M.L.2
  • 12
    • 50249084453 scopus 로고    scopus 로고
    • Brain structural and functional abnormalities in mood disorders: Implications for neurocircuitry models of depression
    • Drevets WC, Price JL, Furey ML (2008). Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct 213: 93-118.
    • (2008) Brain Struct Funct , vol.213 , pp. 93-118
    • Drevets, W.C.1    Price, J.L.2    Furey, M.L.3
  • 14
    • 0033955194 scopus 로고    scopus 로고
    • Gender differences in depression and antidepressant pharmacokinetics and adverse events
    • Frackiewicz EJ, Sramek JJ, Cutler NR (2000). Gender differences in depression and antidepressant pharmacokinetics and adverse events. Ann Pharmacother 34: 80-88.
    • (2000) Ann Pharmacother , vol.34 , pp. 80-88
    • Frackiewicz, E.J.1    Sramek, J.J.2    Cutler, N.R.3
  • 15
    • 33749333018 scopus 로고    scopus 로고
    • Antidepressant efficacy of the antimuscarinic drug scopolamine: A randomized, placebo-controlled clinical trial
    • Furey ML, Drevets WC (2006). Antidepressant efficacy of the antimuscarinic drug scopolamine: a randomized, placebo-controlled clinical trial. Arch Gen Psychiatry 63: 1121-1129.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1121-1129
    • Furey, M.L.1    Drevets, W.C.2
  • 16
    • 1942509496 scopus 로고    scopus 로고
    • Effects of raloxifene and estradiol on hippocampal acetylcholine release and spatial learning in the rat
    • Gibbs RB, Gabor R, Cox T, Johnson DA (2004). Effects of raloxifene and estradiol on hippocampal acetylcholine release and spatial learning in the rat. Psychoneuroendocrinology 29: 741-748.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 741-748
    • Gibbs, R.B.1    Gabor, R.2    Cox, T.3    Johnson, D.A.4
  • 18
    • 34247239822 scopus 로고    scopus 로고
    • Effects of female sex hormones on responses to CGRP, acetylcholine, and 5-HT in rat isolated arteries
    • Gupta S, Mehrotra S, Villalon C, De Vries R, Garrelds I, Saxena P et al (2007). Effects of female sex hormones on responses to CGRP, acetylcholine, and 5-HT in rat isolated arteries. Headache 47: 564-575.
    • (2007) Headache , vol.47 , pp. 564-575
    • Gupta, S.1    Mehrotra, S.2    Villalon, C.3    De Vries, R.4    Garrelds, I.5    Saxena, P.6
  • 19
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M (1959). The assessment of anxiety states by rating. Br J Med Psychol 32: 50-55.
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 20
    • 0036253430 scopus 로고    scopus 로고
    • Interaction of a muscarinic cholinergic agonist on acetylcholine and dopamine receptors in the monkey brain studied with positron emission tomography
    • Hartvig P, Nordberg A, Torstenson R, Sjoberg P, Fasth KJ, Langstrom B (2002). Interaction of a muscarinic cholinergic agonist on acetylcholine and dopamine receptors in the monkey brain studied with positron emission tomography. Dement Geriatr Cogn Disord 13: 199-204.
    • (2002) Dement Geriatr Cogn Disord , vol.13 , pp. 199-204
    • Hartvig, P.1    Nordberg, A.2    Torstenson, R.3    Sjoberg, P.4    Fasth, K.J.5    Langstrom, B.6
  • 22
    • 0015520940 scopus 로고
    • A cholinergic-adrenergic hypothesis of mania and depression
    • Janowsky DS, el-Yousef MK, Davis JM, Sekerke HJ (1972). A cholinergic-adrenergic hypothesis of mania and depression. Lancet 2: 632-635.
    • (1972) Lancet , vol.2 , pp. 632-635
    • Janowsky, D.S.1    El-Yousef, M.K.2    Davis, J.M.3    Sekerke, H.J.4
  • 23
    • 0025373526 scopus 로고
    • Cholinergic dysfunction in depression
    • Janowsky DS, Overstreet DH (1990). Cholinergic dysfunction in depression. Pharmacol Toxicol 66(Suppl 3): 100-111.
    • (1990) Pharmacol Toxicol , vol.66 , Issue.SUPPL. 3 , pp. 100-111
    • Janowsky, D.S.1    Overstreet, D.H.2
  • 24
    • 0028674101 scopus 로고
    • Is cholinergic sensitivity a genetic marker for the affective disorders?
    • Janowsky DS, Overstreet DH, Nurnberger Jr JI (1994). Is cholinergic sensitivity a genetic marker for the affective disorders? Am J Med Genet 54: 335-344.
    • (1994) Am J Med Genet , vol.54 , pp. 335-344
    • Janowsky, D.S.1    Overstreet, D.H.2    Nurnberger Jr., J.I.3
  • 26
    • 0036841511 scopus 로고    scopus 로고
    • Relative sensitivity of the Montgomery-Asberg Depression Rating Scale, the Hamilton Depression rating scale and the Clinical Global Impressions rating scale in antidepressant clinical trials
    • Khan A, Khan SR, Shankles EB, Polissar NL (2002). Relative sensitivity of the Montgomery-Asberg Depression Rating Scale, the Hamilton Depression rating scale and the Clinical Global Impressions rating scale in antidepressant clinical trials. Int Clin Psychopharmacol 17: 281-285.
    • (2002) Int Clin Psychopharmacol , vol.17 , pp. 281-285
    • Khan, A.1    Khan, S.R.2    Shankles, E.B.3    Polissar, N.L.4
  • 28
    • 0019291913 scopus 로고
    • Influence of estrogens on tuberoinfundibular and striatal dopa-minergic systems in the rat
    • Labrie F, Ferland L, Veilleux R, Euvrard C, Boissier J (1980). Influence of estrogens on tuberoinfundibular and striatal dopa-minergic systems in the rat. Acta Psychiatr Belg 80: 658-673.
    • (1980) Acta Psychiatr Belg , vol.80 , pp. 658-673
    • Labrie, F.1    Ferland, L.2    Veilleux, R.3    Euvrard, C.4    Boissier, J.5
  • 29
    • 77952136563 scopus 로고    scopus 로고
    • Acetylcholine-dopamine interactions in the pathophysiology and treatment of CNS disorders
    • Lester DB, Rogers TD, Blaha CD (2010). Acetylcholine-dopamine interactions in the pathophysiology and treatment of CNS disorders. CNS Neurosci Ther 16: 137-162.
    • (2010) CNS Neurosci Ther , vol.16 , pp. 137-162
    • Lester, D.B.1    Rogers, T.D.2    Blaha, C.D.3
  • 30
    • 3142704372 scopus 로고    scopus 로고
    • Muscarinic receptors modulate the mRNA expression of NMDA receptors in brainstem and the release of glutamate in periaqueductal grey during morphine withdrawal in rats
    • Liu HF, Zhou WH, Xie XH, Cao JL, Gu J, Yang GD (2004). [Muscarinic receptors modulate the mRNA expression of NMDA receptors in brainstem and the release of glutamate in periaqueductal grey during morphine withdrawal in rats]. Sheng Li Xue Bao 56: 95-100.
    • (2004) Sheng Li Xue Bao , vol.56 , pp. 95-100
    • Liu, H.F.1    Zhou, W.H.2    Xie, X.H.3    Cao, J.L.4    Gu, J.5    Yang, G.D.6
  • 31
    • 0034952829 scopus 로고    scopus 로고
    • Gender differences in the efficacy of fluoxetine and maprotiline in depressed patients: A double-blind trial of antidepressants with serotonergic or norepinephrinergic reuptake inhibition profile
    • Martenyi F, Dossenbach M, Mraz K, Metcalfe S (2001). Gender differences in the efficacy of fluoxetine and maprotiline in depressed patients: a double-blind trial of antidepressants with serotonergic or norepinephrinergic reuptake inhibition profile. Eur Neuropsychopharmacol 11: 227-232.
    • (2001) Eur Neuropsychopharmacol , vol.11 , pp. 227-232
    • Martenyi, F.1    Dossenbach, M.2    Mraz, K.3    Metcalfe, S.4
  • 32
    • 0035912705 scopus 로고    scopus 로고
    • Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation
    • McEwen B, Akama K, Alves S, Brake WG, Bulloch K, Lee S et al (2001). Tracking the estrogen receptor in neurons: implications for estrogen-induced synapse formation. Proc Natl Acad Sci USA 98: 7093-7100.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7093-7100
    • McEwen, B.1    Akama, K.2    Alves, S.3    Brake, W.G.4    Bulloch, K.5    Lee, S.6
  • 34
    • 0034940379 scopus 로고    scopus 로고
    • Definitions of antidepressant treatment response, remission, nonresponse, partial response, and other relevant outcomes: A focus on treatment-resistant depression
    • Nierenberg AA, DeCecco LM (2001). Definitions of antidepressant treatment response, remission, nonresponse, partial response, and other relevant outcomes: a focus on treatment-resistant depression. J Clin Psychiatry 62(Suppl 16): 5-9.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 16 , pp. 5-9
    • Nierenberg, A.A.1    Dececco, L.M.2
  • 36
    • 0030037417 scopus 로고    scopus 로고
    • Potential animal model of multiple chemical sensitivity with cholinergic supersensitivity
    • Overstreet DH, Miller CS, Janowsky DS, Russell RW (1996). Potential animal model of multiple chemical sensitivity with cholinergic supersensitivity. Toxicology 111: 119-134.
    • (1996) Toxicology , vol.111 , pp. 119-134
    • Overstreet, D.H.1    Miller, C.S.2    Janowsky, D.S.3    Russell, R.W.4
  • 37
    • 0346461630 scopus 로고    scopus 로고
    • Glutamate and depression: Clinical and preclinical studies
    • Paul IA, Skolnick P (2003). Glutamate and depression: clinical and preclinical studies. Ann NY Acad Sci 1003: 250-272.
    • (2003) Ann NY Acad Sci , vol.1003 , pp. 250-272
    • Paul, I.A.1    Skolnick, P.2
  • 38
    • 33744799688 scopus 로고    scopus 로고
    • Gender differences in response to antidepressant treatment prescribed in primary care. Does menopause make a difference?
    • Pinto-Meza A, Usall J, Serrano-Blanco A, Suarez D, Haro JM (2006). Gender differences in response to antidepressant treatment prescribed in primary care. Does menopause make a difference? J Affect Disord 93: 53-60.
    • (2006) J Affect Disord , vol.93 , pp. 53-60
    • Pinto-Meza, A.1    Usall, J.2    Serrano-Blanco, A.3    Suarez, D.4    Haro, J.M.5
  • 39
    • 1542321106 scopus 로고    scopus 로고
    • Estrogen-mediated regulation of cholinergic expression in basal forebrain neurons requires extracellular-signal-regulated kinase activity
    • Pongrac JL, Gibbs RB, Defranco DB (2004). Estrogen-mediated regulation of cholinergic expression in basal forebrain neurons requires extracellular- signal-regulated kinase activity. Neu-roscience 124: 809-816.
    • (2004) Neu-roscience , vol.124 , pp. 809-816
    • Pongrac, J.L.1    Gibbs, R.B.2    Defranco, D.B.3
  • 41
    • 0028219668 scopus 로고
    • Sleep in depression: The influence of age, gender and diagnostic subtype on baseline sleep and the cholinergic REM induction test with RS 86
    • Riemann D, Hohagen F, Bahro M, Berger M (1994a). Sleep in depression: the influence of age, gender and diagnostic subtype on baseline sleep and the cholinergic REM induction test with RS 86. Eur Arch Psychiatry Clin Neurosci 243: 279-290.
    • (1994) Eur Arch Psychiatry Clin Neurosci , vol.243 , pp. 279-290
    • Riemann, D.1    Hohagen, F.2    Bahro, M.3    Berger, M.4
  • 42
    • 0028304364 scopus 로고
    • Cholinergic REM induction test: Muscarinic supersensitivity underlies polysomnographic findings in both depression and schizophrenia
    • Riemann D, Hohagen F, Krieger S, Gann H, Muller WE, Olbrich R et al (1994b). Cholinergic REM induction test: muscarinic supersensitivity underlies polysomnographic findings in both depression and schizophrenia. J Psychiatr Res 28: 195-210.
    • (1994) J Psychiatr Res , vol.28 , pp. 195-210
    • Riemann, D.1    Hohagen, F.2    Krieger, S.3    Gann, H.4    Muller, W.E.5    Olbrich, R.6
  • 43
    • 0038532259 scopus 로고    scopus 로고
    • Growth hormone responses to low-dose physostigmine administration: Functional sex differences (sexual diergism) between major depressives and matched controls
    • Rubin RT, Abbasi SA, Rhodes ME, Czambel RK (2003). Growth hormone responses to low-dose physostigmine administration: functional sex differences (sexual diergism) between major depressives and matched controls. Psychol Med 33: 655-665.
    • (2003) Psychol Med , vol.33 , pp. 655-665
    • Rubin, R.T.1    Abbasi, S.A.2    Rhodes, M.E.3    Czambel, R.K.4
  • 44
    • 0032787663 scopus 로고    scopus 로고
    • Hypothalamo-pituitary-adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: Sex differences between major depressives and matched control subjects
    • Rubin RT, O'Toole SM, Rhodes ME, Sekula LK, Czambel RK (1999). Hypothalamo-pituitary-adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: sex differences between major depressives and matched control subjects. Psychiatry Res 89: 1-20.
    • (1999) Psychiatry Res , vol.89 , pp. 1-20
    • Rubin, R.T.1    O'Toole, S.M.2    Rhodes, M.E.3    Sekula, L.K.4    Czambel, R.K.5
  • 45
    • 0032213937 scopus 로고    scopus 로고
    • Estrogen-serotonin interactions: Implications for affective regulation
    • Rubinow DR, Schmidt PJ, Roca CA (1998). Estrogen-serotonin interactions: implications for affective regulation. Biol Psychiatry 44: 839-850.
    • (1998) Biol Psychiatry , vol.44 , pp. 839-850
    • Rubinow, D.R.1    Schmidt, P.J.2    Roca, C.A.3
  • 46
    • 0032780061 scopus 로고    scopus 로고
    • Basal forebrain afferent projections modulating cortical acetylcholine, attention, and implications for neuropsychiatric disorders
    • Sarter M, Bruno JP, Turchi J (1999). Basal forebrain afferent projections modulating cortical acetylcholine, attention, and implications for neuropsychiatric disorders. Ann NY Acad Sci 877: 368-382.
    • (1999) Ann NY Acad Sci , vol.877 , pp. 368-382
    • Sarter, M.1    Bruno, J.P.2    Turchi, J.3
  • 48
    • 71349087103 scopus 로고    scopus 로고
    • Estradiol and the relationship between dendritic spines, NR2B containing NMDA receptors, and the magnitude of long-term potentiation at hippocampal CA3-CA1 synapses
    • Smith CC, Vedder LC, McMahon LL (2009). Estradiol and the relationship between dendritic spines, NR2B containing NMDA receptors, and the magnitude of long-term potentiation at hippocampal CA3-CA1 synapses. Psychoneuroendocrinology 34(Suppl 1): S130-S142.
    • (2009) Psychoneuroendocrinology , vol.34 , Issue.SUPPL. 1
    • Smith, C.C.1    Vedder, L.C.2    McMahon, L.L.3
  • 49
    • 0037341824 scopus 로고    scopus 로고
    • Hormones and mood: From menarche to menopause and beyond
    • Steiner M, Dunn E, Born L (2003). Hormones and mood: from menarche to menopause and beyond. J Affect Disord 74: 67-83.
    • (2003) J Affect Disord , vol.74 , pp. 67-83
    • Steiner, M.1    Dunn, E.2    Born, L.3
  • 50
    • 15744390962 scopus 로고    scopus 로고
    • Estrogen mediated inhibition of dopamine transport in the striatum: Regulation by G alpha i/o
    • Thompson TL, Certain ME (2005). Estrogen mediated inhibition of dopamine transport in the striatum: regulation by G alpha i/o. Eur J Pharmacol 511: 121-126.
    • (2005) Eur J Pharmacol , vol.511 , pp. 121-126
    • Thompson, T.L.1    Certain, M.E.2
  • 51
    • 4544236290 scopus 로고    scopus 로고
    • Evidence of common and specific genetic effects: Association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome
    • Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S et al (2004). Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Hum Mol Genet 13: 1903-1911.
    • (2004) Hum Mol Genet , vol.13 , pp. 1903-1911
    • Wang, J.C.1    Hinrichs, A.L.2    Stock, H.3    Budde, J.4    Allen, R.5    Bertelsen, S.6
  • 52
    • 0027987251 scopus 로고
    • Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism
    • Woolley CS, McEwen BS (1994). Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism. J Neurosci 14: 7680-7687.
    • (1994) J Neurosci , vol.14 , pp. 7680-7687
    • Woolley, C.S.1    McEwen, B.S.2
  • 53
    • 1542440486 scopus 로고    scopus 로고
    • Special issues related to the treatment of depression in women
    • Yonkers KA (2003). Special issues related to the treatment of depression in women. J Clin Psychiatry 64(Suppl 18): 8-13.
    • (2003) J Clin Psychiatry , vol.64 , Issue.SUPPL. 18 , pp. 8-13
    • Yonkers, K.A.1
  • 54
    • 0018175277 scopus 로고
    • A rating scale for mania: Reliability, validity and sensitivity
    • Young RC, Biggs JT, Ziegler VE, Meyer DA (1978). A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 133: 429-435.
    • (1978) Br J Psychiatry , vol.133 , pp. 429-435
    • Young, R.C.1    Biggs, J.T.2    Ziegler, V.E.3    Meyer, D.A.4
  • 55
    • 33745655207 scopus 로고    scopus 로고
    • Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors
    • Zhang Z, Chen K, Shih JC, Teng CT (2006). Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors. Mol Endocrinol 20: 1547-1561.
    • (2006) Mol Endocrinol , vol.20 , pp. 1547-1561
    • Zhang, Z.1    Chen, K.2    Shih, J.C.3    Teng, C.T.4


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