Uric Acid: A Danger Signal From the RNA World That May Have a Role in the Epidemic of Obesity, Metabolic Syndrome, and Cardiorenal Disease: Evolutionary Considerations

Seminars in Nephrology

Volumn 31, Issue 5, 2011, Pages 394-399

  Johnson, Richard J ^a   Lanaspa, Miguel A ^a   Gaucher, Eric A ^b  

^a UNIVERSITY OF COLORADO   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Anti oxidant; Fructose; Oxidant; RNA world; Thrifty gene; Uricase

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; FRUCTOSE; RNA; URATE OXIDASE; URIC ACID;

ANTIOXIDANT ACTIVITY; APE; ARTICLE; CLIMATE; COOLING; DIABETES MELLITUS; EVOLUTION; FRUCTOSE METABOLISM; GENE; GENE MUTATION; GLOBAL COOLING; GOUT; HUMAN; HYPERTENSION; HYPERURICEMIA; INTELLIGENCE; KIDNEY DISEASE; METABOLIC SYNDROME X; MULTIINFARCT DEMENTIA; NEPHROLITHIASIS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PREECLAMPSIA; PRIORITY JOURNAL; STARVATION; SURVIVAL; URIC ACID BLOOD LEVEL; URICASE GENE;

ANIMALS; BIOLOGICAL EVOLUTION; CARDIO-RENAL SYNDROME; HUMANS; METABOLIC SYNDROME X; MUTATION; OBESITY; RNA; URATE OXIDASE; URIC ACID;

EID: 80054082041     PISSN: 02709295     EISSN: 15584488     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2011.08.002     Document Type: Article

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