Fructose, uricase, and the Back-to-Africa hypothesis

Evolutionary Anthropology

Volumn 19, Issue 6, 2010, Pages 250-257

  Johnson, Richard J ^a   Andrews, Peter ^a  

^a NONE

Author keywords

Evolution; Fructose; Hominoid; Urate oxidase; Uric acid

Indexed keywords

HOMINIDAE; HOMINOIDEA; HOMO;

EID: 78651299436     PISSN: 10601538     EISSN: 15206505     Source Type: Journal    
DOI: 10.1002/evan.20266     Document Type: Article

References (82)

1. Andrews P, Martin L. 1991. Hominoid dietary evolution. Philos Trans R Soc Lond B Biol Sci 334: 199-209.
2. Teaford MF, Ungar P. 2007. Dental adaptations of African apes. In: Henke K, Tattersall I, Hardt T, editors. Handbook of palaeoanthropology. Berlin: Springer. p 1107-1130.
3. Ungar PS. 2006. Early human diets: the known, the unknown and the unknowable. Oxford: Oxford University Press.
4. Suc JP. 1999. Neogene vegetation change in West European and West circum-Mediterranean areas. In: Agusti L, Rook L, Andrews P, editors. The evolution of neogene terrestrial ecosystems in Europe. Cambridge: Cambridge University Press. p 378-384.
5. Laden G, Wrangham R. 2005. The rise of the hominids as an adaptive shift in fallback foods: plant underground storage organs (USOs) and australopith origins. J Hum Evol 49: 482-498.
6. Marshall AJ, Wrangham R. 2007. Evolutionary consequences of fallback foods. Int J Primatol 28: 1219-1235.
7. Oda M, Satta Y, Takenaka O, Takahata N. 2002. Loss of urate oxidase activity in hominoids and its evolutionary implications. Mol Biol Evol 19: 640-653.
8. Eronen JT, Rook L. 2004. The Mio-Pliocene European primate fossil record: dynamics and habitat tracking. J Hum Evol 47: 323-341.
9. Harrison T. 2002. Late Oligocene to middle Miocene catarrhines from Afro-Arabia. In: Hartwig W, editor. The primate fossil record. Cambridge: Cambridge University Press. p 311-338.
10. Kay RF, Simons EL. 1980. The ecology of Oligocene African Anthropoidea. Int J Primatol 1: 21-37.
11. Rögl F. 1999. Mediterranean and Paratethys paelogeography during the Oligocene and Miocene. In: Agusti J, Rook L, Andrews P, editors. The evolution of Neogene terrestrial ecosystems in Europe. Cambridge: Cambridge University Press. p 8-22.
12. Heizmann EP, Begun DR. 2001. The oldest Eurasian hominoid. J Hum Evol 41: 463-481.
13. Andrews P, Kelley J. 2007. Middle Miocene dispersals of apes. Folia Primatol 78: 328-343.
14. Andrews P, Tobien H. 1977. New Miocene locality in Turkey, with evidence on the origins of Ramapithecus and Sivapithecus. Nature 268: 699-701.
15. Begun DR, Geraads D, Gulec E. 2003. The Çandir hominoid locality: implications for the timing and pattern of hominoid dispersal events. Cour Forschung Inst Senckenberg 240: 251-265.
16. Begun DR. 2001. African and Eurasian Miocene hominoids and the origins of the Hominidae. In: Andrews P, Koufos G, DeBonis L, editors. Hominoid evolution and enviromental change in the Neogene of Europe. Cambridge: Cambridge University Press. p 231-253.
17. Andrews P. 1990. Paleoecology of the Miocene fauna from Paşalar, Turkey. J Hum Evol 19: 569-582.
18. Bestland EA. 1990. Sedimentology and paleopedology of Miocene alluvial deposits at the Pasalar hominoid site, western Turkey. J Hum Evol 19: 363-377.
19. Retallack GJ, Dugas DP, Bestland EA. 1990. Fossil soils and grasses of a middle Miocene East African grassland. Science 247: 1325-1328.
20. Denton GH. 1999. Cenozoic climate change. In: Bromage TD, Schrenk F, editors. African biogeography, climate change and human evolution. Oxford: Oxford University Press. p 94-114.
21. White F. 1983. The vegetation of Africa, a descriptive memoir to accompany the UNESCO/AETFAT/UNSO vegetation map of Africa. In: Res. NR, editor. UNESCO. p 1-356.
22. King T, Aiello L, Andrews P. 1999. Dental microwear of Griphopithecus alpani. J Hum Evol 36: 3-31.
23. Ersoy A, Kelley J, Andrews P, Alpagut B. 2008. Hominoid phalanges from the middle Miocene of Paşalar, Turkey. J Hum Evol 54: 518-529.
24. Bohme M. 2003. The Miocene climatic optimum:evidence from ectothermic vertebrates of Central Europe. Palaeogeorg Palaeoclimat Palaeoecol 195: 389-401.
25. Fortelius M, Eronen J, Liu LP, Pushkina D, Tesakov A, Vislobokova I, Zhang ZQ. 2003. Continental-scale hypsodonty patterns, climatic paleobiogrography and dispersal of Eurasian Neogene large mammal herbivores. Deinsea 10: 1-11.
26. Agusti J, Sanz de Siria A, Garces M. 2003. Explaining the end of the hominoid experiment in Europe. J Hum Evol 45: 145-153.
27. Andrews P, Bernor R. 1999. Vicariance biogeography and paleoecology of Eurasian Miocene hominoid primates. In: Agusti J, Rook L, Andrews P, editors. Hominoid evolution and climatic change in Europe. Cambridge: Cambridge University Press. p 454-487.
28. Kelley J, Andrews P, Alpagut B. 2008. A new hominoid species from the middle Miocene site of Pasalar, Turkey. J Hum Evol 54: 455-479.
29. Begun DR, Gulec E, Geraads D. 2003. Dispersal patterns of Eurasian hominoids: implications from Turkey. Deinsea 10: 23-39.
30. Agusti J, Cabrera L, Garces M, Llenas M. 1999. Mammal turnover and global climate change in the late miocene terrestrial record of the Valles-Penedes basin (NE Spain). In: Agusti J, Rook L, Andrews P, editors. The evolution of Neogene terrestrial ecosystems in Europe. Cambridge: Cambridge University Press. p 397-412.
31. Skinner MF, Dupras TL, Moya-Sola S. 1995. Periodicity of linear enamel hypoplasia among Miocene Dryopithecus from Spain. J Paleopathol 7: 195-222.
32. Skinner MF, Hopwood D. 2004. Hypothesis for the causes and periodicity of repetitive linear enamel hypoplasia in large, wild African (Pan troglodytes and Gorilla gorilla) and Asian (Pongo pygmaeus) apes. Am J Phys Anthropol 123: 216-235.
33. Begun DR. 2002. European hominoids. In: Hartwig WC, editor. The primate fossil record. Cambridge: Cambridge University Press. p 339-368.
34. Bernor R, Tobien H. 1990. The mammalian geochronology and biogeography of Paşalar (Middle Miocene, Turkey). J Hum Evol 19: 551-568.
35. Begun DR. 2005. Sivapithecus is east and Dryopithecus is west, and never the twain shall meet. Anthropol Sci 113: 53-64.
36. Begun DR. 2007. Primate evolution and human origins. In: Henke W, Rothe H, Tattersall I, editors. Handbook of palaeoanthropology. Berlin: Springer. p 921-997.
37. Stewart CB, Disotell TR. 1998. Primate evolution: in and out of Africa. Curr Biol 8: R582-588.
38. Goodman M, Porter CA, Czelusniak J, Page SL, Schneider H, Shoshani J, Gunnell G, Groves CP. 1998. Toward a phylogenetic classification of Primates based on DNA evidence complemented by fossil evidence. Mol Phylogenet Evol 9: 585-598.
39. Andrews P, Cronin JE. 1982. The relationships of Sivapithecus and Ramapithecus and the evolution of the orang-utan. Nature 297: 541-546.
40. Pilbeam D, Rose MD, Barry JC, Shah SM. 1990. New Sivapithecus humeri from Pakistan and the relationship of Sivapithecus and Pongo. Nature 348: 237-239.
41. Moya-Sola S, Kohler M. 1996. A Dryopithecus skeleton and the origins of great-ape locomotion. Nature 379: 156-159.
42. Grehan JR, Schwartz JH. 2009. Evolution of the second orangutan: phylogeny and biogeography of hominid origins. J Biogeogr 36: 1823-1844.
43. Havel PJ. 2005. Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism. Nutr Rev 63: 133-157.
44. Johnson RJ, Perez-Pozo SE, Sautin YY, Manitius J, Sanchez-Lozada LG, Feig DI, Shafiu M, Segal M, Glassock RJ, Shimada M. 2009. Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes? Endocrino Rev 30: 96-116.
45. Ouyang X, Cirillo P, Sautin Y, McCall S, Bruchette JL, Diehl AM, Johnson RJ, Abdelmalek MF. 2008. Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J Hepatol 48: 993-999.
46. Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W. 2009. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest 119: 1322-1334.
47. Roncal CA, Reungjui S, Sanchez-Lozada LG, Mu W, Sautin YY, Nakagawa T, Johnson RJ. 2009. Combination of captopril and allopurinol retards fructose-induced metabolic syndrome. Am J Nephrol 30: 399-404.
48. Bruynseels K, Bergans N, Gillis N, van Dorpen F, Van Hecke P, Stalmans W, Vanstapel F. 1999. On the inhibition of hepatic glycogenolysis by fructose: a 31P-NMR study in perfused rat liver using the fructose analogue 2, 5-anhydro-D-mannitol. NMR Biomed 12: 145-156.
49. Teff KL, Elliott SS, Tschop M, Kieffer TJ, Rader D, Heiman M, Townsend RR, Keim NL, D'Alessio D, Havel PJ. 2004. Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women. J Clin Endocrinol Metab 89: 2963-2972.
50. Shapiro A, Mu W, Roncal C, Cheng KY, Johnson RJ, Scarpace PJ. 2008. Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding. Am J Physiol Regul Integr Comp Physiol 295: R1370-1375.
51. Avena NM, Rada P, Hoebel BG. 2006. Sugar bingeing in rats. In: Gerfen C, Holmes A, Sibley D, Stolnick P, Wray S, editors. Current Protocols in Neuroscience. Princeton: Princeton University Press. (to be addressed by authors), Chapter 9:Unit9 23C.
52. Reaven GM. 1999. Insulin resistance, the key to survival: a rose by any other name. Diabetologia 42: 384-385.
53. Vasdev S, Gill V, Parai S, Gadag V. 2007. Fructose-induced hypertension in Wistar-Kyoto rats: interaction with moderately high dietary salt. Can J Physiol Pharmacol 85: 413-421.
54. Johnson RJ, Sautin YY, Oliver WJ, Roncal C, Mu W, Gabriela Sanchez-Lozada L, Rodriguez-Iturbe B, Nakagawa T, Benner SA. 2009. Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in Western society? J Comp Physiol [B] 179: 67-76.
55. Knott CD. 1998. Changes in orangutan caloric intake, energy balance, and ketones in response to fluctuating fruit availability. Int J Primatol 19: 1061-1079.
56. Nakagawa T, Hu H, Zharikov S, Tuttle KR, Short RA, Glushakova O, Ouyang X, Feig DI, Block ER, Herrera-Acosta J. 2006. A causal role for uric acid in fructose-induced metabolic syndrome. Am J Physiol Renal Physiol 290: F625-631.
57. Van den Berghe G. 1986. Fructose: metabolism and short-term effects on carbohydrate and purine metabolic pathways. Prog Biochem Pharmacol 21: 1-32.
58. Hallfrisch J. 1990. Metabolic effects of dietary fructose. Faseb J 4: 2652-2660.
59. Odievre M, Gentil C, Gautier M, Alagille D. 1978. Hereditary fructose intolerance in childhood: diagnosis, management, and course in 55 patients. Am J Dis Child 132: 605-608.
60. Yu MA, Sanchez-Lozada LG, Johnson RJ, Kang DH. n.d. Uric acid: an inducer of oxidative stress and renin angiotensin system in human vascular endothelial cells. J Hypertens. In press.
61. Corry DB, Eslami P, Yamamoto K, Nyby MD, Makino H, Tuck ML. 2008. Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system. J Hypertens 26: 269-275.
62. Sautin YY, Nakagawa T, Zharikov S, Johnson RJ. 2007. Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am J Physiol Cell Physiol 293: C584-5796.
63. Sanchez-Lozada LG, Tapia E, Jimenez A, Bautista P, Cristobal M, Nepomuceno T, Soto V, Avila-Casado C, Nakagawa T, Johnson RJ. 2007. Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol 292: F423-429.
64. Cheung KJ, Tzameli I, Pissios P, Rovira I, Gavrilova O, Ohtsubo T, Chen Z, Finkel T, Flier JS, Friedman JM. 2007. Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity. Cell Metab 5: 115-128.
65. Shi Y, Evans JE, Rock KL. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425: 516-521.
66. Barrera CM, Hunter RE, Dunlap WP. 1989. Hyperuricemia and locomotor activity in developing rats. Pharmacol Biochem Behav 33: 367-369.
67. Orowan E. 1955. The origin of man. Nature 175: 683-684.
68. Bloch S, Brackenridge CJ. 1972. Psychological, performance and biochemical factors in medical students under examination stress. J Psychosom Res 16: 25-33.
69. Brooks GW, Mueller E. 1966. Serum urate concentrations among university professors; relation to drive, achievement, and leadership. JAMA 195: 415-418.
70. Wacker WE. 1970. Man: sapient but gouty. N Engl J Med 283: 151-152.
71. Christen P, Peacock WC, Christen AE, Wacker WE. 1970. Urate oxidase in primate phylogenesis. Eur J Biochem 12: 3-5.
72. Stavric B, Johnson WJ, Clayman S, Gadd RE, Chartrand A. 1976. Effect of fructose administration on serum urate levels in the uricase inhibited rat. Experientia 32: 373-374.
73. Haldane JBS. 1932. The causes of evolution. Princeton, NJ: Princeton University Press.
74. O'Brien E, Peters C. 1999. Climatic perspectives for Neogene environmental reconstructions. In: Agusti J, Rook L, Andrews P, editors. Hominoid evolution and climatic change in Europe. Cambridge: Cambridge University Press. p 55-81.
75. Ames BN, Cathcart R, Schwiers E, Hochstein P. 1981. Uric acid provides an antioxidant defense in humans against oxidant-and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci USA 78: 6858-6862.
76. Feig DI, Soletsky B, Johnson RJ. 2008. Effect of allopurinol on the blood pressure of adolescents with newly diagnosed essential hypertension. JAMA 300: 922-930.
77. Ogino K, Kato M, Furuse Y, Kinugasa Y, Ishida K, Osaki S, Kinugawa T, Igawa O, Hisatome I, Shigemasa C. Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study. Circ Heart Fail 3: 73-81.
78. Perez-Pozo SE, Schold J, Nakagawa T, Sanchez-Lozada LG, Johnson RJ, Lillo JL. 2009. Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response. Int J Obes (Lond). 34: 454-461.
79. Marshall AJ, Wrangham RW. 2007. Evolutionary consequences of fallback foods. Int J Primatol 28: 1219-1235.
80. Boesch C, Boesch-Achermann H. 2000. The chimpanzees of the Tai forest: behavioural ecology and evolution. Oxford: Oxford University Press.
81. Johnson RJ, Andrews P, Benner SA, Oliver WJ. n.d.Theodore E. Woodward Award. The evolution of obesity: insights from the Mid Miocene. Trans Am Clin Climatol Assoc. In press.
82. Neel JV. 1962. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet 14: 353-362.