Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke

Stroke

Volumn 34, Issue 8, 2003, Pages 1951-1956

  Weir, Christopher J ^a   Muir, Scott W ^a   Walters, Matthew R ^a   Lees, Kennedy R ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Mortality; Stroke, acute; Survival; Urate

Indexed keywords

URATE;

ADULT; AGED; ARTICLE; BRAIN HEMORRHAGE; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RECURRENT DISEASE; SURVIVAL; TREATMENT OUTCOME; URIC ACID BLOOD LEVEL;

ACUTE DISEASE; AGED; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; CEREBROVASCULAR ACCIDENT; FEMALE; FOLLOW-UP STUDIES; HUMANS; ISCHEMIC ATTACK, TRANSIENT; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; ODDS RATIO; OUTCOME ASSESSMENT (HEALTH CARE); PREDICTIVE VALUE OF TESTS; PROGNOSIS; RECURRENCE; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; URIC ACID;

EID: 0041402693     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000081983.34771.D2     Document Type: Article

References (33)

1. Abbott RD, Brand FN, Kannel WB, Castelli WP. Gout and coronary heart disease: the Framingham study. J Clin Epidemiol. 1988;41:237-242.
2. Culleton BF, Larson MG, Kannel WB, Levy D. Serum uric acid and risk of cardiovascular disease and mortality: the Framingham Heart Study. Ann Intern Med. 1999;131:7-13.
3. Fang J, Alderman MH. Serum uric acid and cardiovascular mortality: the NHANES I epidemiologic follow-up study, 1971-1992: National Health and Nutrition Examination Survey. JAMA. 2000;283:2404-2410.
4. Jossa F, Farinaro E, Panico S, Krogh V, Celentano E, Galasso R, Mancini M, Trevisan M. Serum uric acid and hypertension: the Olivetti Heart Study. J Hum Hypertens. 1994;8:677-681.
5. Wannamethee SG, Shaper AG, Whincup PH. Serum urate and the risk of major coronary heart disease events. Heart. 1997;78:147-153.
6. Alderman MH, Cohen H, Madhavan S, Kivlighn S. Serum uric acid and cardiovascular events in successfully treated hypertensive patients. Hypertension. 1999;34:144-150.
7. Lehto S, Niskanen L, Ronnemaa T, Laakso M. Serum uric acid is a strong predictor of stroke in patients with non-insulin-dependent diabetes mellitus. Ann Epidemiol. 1996;6:331-340.
8. Mazza A, Pessina AC, Pavei A, Scarpa R, Tikhonoff V, Casiglia E. Predictors of stroke mortality in elderly people from the general population. The Cardiovascular Study in the Elderly. Eur J Epidemiol. 2001;17:1097-1104.
9. Becker BF. Towards the physiological function of uric acid. Free Radic Biol Med. 1993;14:615-631.
10. Bamford JM, Sandercock PAG, Dennis MS, Burn J, Warlow CP. Classification and natural-history of clinically identifiable subtypes of cerebral infarction. Lancet. 1991;337:1521-1526.
11. Lyden PD, Lu M, Levine SR, Brott TG, Broderick J, for the NINDS rtPA Stroke Study Group. A modified National Institutes of Health Stroke Scale for use in stroke clinical trials: preliminary reliability and validity. Stroke. 2001;32:1310-1317.
12. Teasdale G, Jennett B. Assessment of coma and impaired consciousness: a practical scale. Lancet. 1974;2:81-84.
13. Kendrick S, Clarke J. The Scottish record linkage system. Heath Bull (Edinb). 1993;51:1-15.
14. West of Scotland Coronary Prevention Study Group. Computerized record linkage: compared with traditional patient follow-up methods in clinical trials and illustrated in a prospective epidemiological study. J Clin Epidemiol. 1995;48:1441-1452.
15. Cox DR. Regression models and life tables. J R Statist Soc B. 1972;34:187-220.
16. CAPRIE Steering Committee. A randomised, blinded, trial of Clopidogrel Versus Aspirin in Patients at Risk of Ischaemic Events (CAPRIE). Lancet. 1996;348:1329-1339.
17. Coronary Drug Project Research Group. Serum uric acid: its association with other risk factors and with mortality in coronary heart disease. J Chronic Dis. 1976;29:557-569.
18. Hill AB. The environment and disease: association or causation? Proc R Soc Med. 1965;58:295-300.
19. Dobson A. Is raised serum uric acid a cause of cardiovascular disease or death? Lancet. 1999;354:1578.
20. San Diego R, Pan D, Morisky D, Enonmoh A, Fong R, Ward H. Elevated serum uric acid levels are associated with increased hypertension morbidity in the minority population. Am J Hypertens. 1999;12(suppl A):13A. Abstract.
21. Staessen J, for the European Working Party on High Blood Pressure in the Elderly. The determinants and prognostic significance of serum uric acid in elderly patients of the European Working Party on High Blood Pressure in the Elderly trial. Am J Med. 1991;90(suppl 3A): 50S-54S.
22. Chamorro A, Obach V, Cervera A, Revilla M, Deulofeu R, Aponte JH. Prognostic significance of uric acid serum concentration in patients with acute ischemic stroke. Stroke. 2002;33:1048-1052.
23. DeScheeder IK, van de Kraay AM, Lamers JM, Koster JF, deJong JW, Serruys PW. Myocardial malondialdehyde and uric acid release after short-lasting coronary occlusions during angioplasty: potential mechanisms for free radical generation. Am J Cardiol. 1991;68:392-395.
24. Ginsberg MH, Kozin F, O'Malley M, McCarty DJ. Release of platelet constituents by monosodium urate crystals. J Clin Invest. 1997;60:999-1007.
25. Iribarren C, Folsom AR, Eckfeldt JH, McGovern PG, Nieto FJ. Correlates of uric acid and its association with asymptomatic carotid atherosclerosis: the ARIC Study: Atherosclerosis Risk in Communities. Stroke. 1999;29:635-639.
26. Suarna C, Dean RT, May J, Stocker R. Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate. Arterioscler Thromb Vasc Biol. 1995;15:1616-1624.
27. Mazzali M, Hughes J, Kim YG, Jefferson JA, Kang D-H, Gordon KL, Lan HY, Kivlighn S, Johnson RJ. Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism. Hypertension. 2001;38:1101-1106.
28. Watanabe S, Kang D-H, Feng L, Nakagawa T, Kanellis J, Lan H, Mazzali M, Johnson RJ. Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity. Hypertension. 2002;40:356-360.
29. Sanchez-Lozada LG, Tapia E, Avila-Casado C, Soto V, Franco M, Santamaria J, Nakagawa T, Rodriguez-Iturbe B, Johnson RJ, Herrera-Acosta J. Mild hyperuricemia induces glomerular hypertension in normal rats. Am J Physiol Renal Physiol. 2002;283:F1105-F1110.
30. Kang D-H, Nakagawa T, Feng L, Watanabe S, Han L, Mazzali M, Truong L, Harris R, Johnson RJ. A role for uric acid in the progression of renal disease. J Am Soc Nephrol. 2002;13:2888-2897.
31. Mazzali M, Kanellis J, Han L, Feng L, Xia Y-Y, Chen Q, Kang D-H, Gordon KL, Watanabe S, Nakagawa T, et al. Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol. 2002;282:F991-F997.
32. PROGRESS Collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet. 2001;358:1033-1041.
33. Fox R. Am Heart Association 2001 scientific sessions: late-breaking science-statins: the new aspirin? Circulation. 2001;104: E9051-E9052.