Exploring the activation mechanism of TRPM8 channel by targeted MD simulations

Biochemical and Biophysical Research Communications

Volumn 414, Issue 1, 2011, Pages 14-19

  Pedretti, Alessandro ^a   Labozzetta, Alessandra ^a   Lo Monte, Matteo ^a   Beccari, Andrea R ^b   Moriconi, Alessio ^b   Vistoli, Giulio ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Research and Development Centre   (Italy)

Author keywords

Docking analysis; MD simulations; Menthol; Pore opening; TRPM8 channel; Voltage sensor module

Indexed keywords

1 (2 HYDROXYPHENYL) 4 (3 NITROPHENYL) 1,2,3,6 TETRAHYDROPYRIMIDIN 2 ONE; AMTB; ION TRANSPORT AFFECTING AGENT; MENTHOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DRUG BINDING; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; RELIABILITY; SIMULATION;

HUMANS; MOLECULAR DYNAMICS SIMULATION; TRPM CATION CHANNELS;

EID: 80054068326     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.08.134     Document Type: Article

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