Blocking epidermal growth factor receptor attenuates reactive astrogliosis through inhibiting cell cycle progression and protects against ischemic brain injury in rats

Journal of Neurochemistry

Volumn 119, Issue 3, 2011, Pages 644-653

  Yang, Qin ^a   Wang, En Yin ^b   Huang, Xiao Jiang ^a   Qu, Wen Sheng ^a   Zhang, Lin ^b   Xu, Jin Zhi ^a   Wang, Wei ^a   Tian, Dai Shi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

cell cycle progression; epidermal growth factor receptor; middle cerebral artery occlusion; oxygen glucose deprivation; reactive astrogliosis

Indexed keywords

C225 ANTIBODY; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE; KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUTRALIZING ANTIBODY; OXYGEN; PROTEIN P27; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BRAIN INFARCT VOLUME; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN PROTECTION; CELL ACTIVATION; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; NERVE CELL CULTURE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BLOCKING; REOXYGENATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, MONOCLONAL; ASTROCYTES; BRAIN ISCHEMIA; CELL CYCLE; CELLS, CULTURED; GLIOSIS; MALE; NEUROPROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR;

RATTUS;

EID: 80054067057     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07446.x     Document Type: Article

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