Therapeutic IMC-C225 antibody inhibits breast cancer cell invasiveness via Vav2-dependent activation of RhoA GTPase

Clinical Cancer Research

Volumn 14, Issue 19, 2008, Pages 6161-6170

  Molli, Poonam R ^a   Adam, Liana ^a   Kumar, Rakesh ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CETUXIMAB; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN ANTIBODY; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VAV2 PROTEIN; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; VAV PROTEIN; VAV2 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INVASION; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRESS FIBER; BREAST TUMOR; CHEMISTRY; CYTOSKELETON; FEMALE; IMMUNOLOGY; METABOLISM; METASTASIS; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CYTOSKELETON; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHENOTYPE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-VAV; RECEPTOR, EPIDERMAL GROWTH FACTOR; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN;

EID: 58149161749     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-5288     Document Type: Article

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