메뉴 건너뛰기




Volumn 705, Issue , 2011, Pages 465-492

Mucin O-glycan branching enzymes: Structure, function, and gene regulation

Author keywords

b6N acetylglucosaminyltransferase; Branching enzymes; C2GnT; Mucin O glycan

Indexed keywords

CD34 ANTIGEN; COMPLEMENTARY DNA; CYSTEINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCAN DERIVATIVE; GLYCOSYLTRANSFERASE; L SELECTIN; MUCIN O GLYCAN; PADGEM PROTEIN; RETINOIC ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 1,4 ALPHA GLUCAN BRANCHING ENZYME; MUCIN; N ACETYLGLUCOSAMINYLTRANSFERASE; POLYSACCHARIDE;

EID: 80054037878     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-7877-6_25     Document Type: Conference Paper
Times cited : (22)

References (137)
  • 1
    • 33644620356 scopus 로고    scopus 로고
    • Respiratory tract mucin genes and mucin glycoproteins in health and disease
    • Rose MC, Voynow JA (2006) Respiratory tract mucin genes and mucin glycoproteins in health and disease. Physiol Rev 86:245-278
    • (2006) Physiol Rev , vol.86 , pp. 245-278
    • Rose, M.C.1    Voynow, J.A.2
  • 2
    • 0347123435 scopus 로고    scopus 로고
    • Mucins in cancer: Protection and control of the cell surface
    • Hollingsworth MA, Swanson BJ (2004) Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 4:45-60
    • (2004) Nat Rev Cancer , vol.4 , pp. 45-60
    • Hollingsworth, M.A.1    Swanson, B.J.2
  • 4
    • 0024517925 scopus 로고
    • Sialo-oligosaccharide receptors for mycoplasma pneumoniae and related oligosaccharides of poly-N-acetyllactosamine series are polarized at the cilia and apical-microvillar domains of the ciliated cells in human bronchial epithelium
    • Loveless RW, Feizi T (1989) Sialo-oligosaccharide receptors for mycoplasma pneumoniae and related oligosaccharides of poly-N-acetyllactosamine series are polarized at the cilia and apical-microvillar domains of the ciliated cells in human bronchial epithelium. Infect Immun 57:1285-1289
    • (1989) Infect Immun , vol.57 , pp. 1285-1289
    • Loveless, R.W.1    Feizi, T.2
  • 5
    • 0020770775 scopus 로고
    • Isolation and characterization of receptor sialo-glycoprotein for hemagglutinating virus of Japan (sendai virus) from bovine erythrocyte membrane
    • Suzuki Y, Suzuki T, Matsumoto M (1983) Isolation and characterization of receptor sialo-glycoprotein for hemagglutinating virus of Japan (sendai virus) from bovine erythrocyte membrane. J Biochem 93:1621-1633
    • (1983) J Biochem , vol.93 , pp. 1621-1633
    • Suzuki, Y.1    Suzuki, T.2    Matsumoto, M.3
  • 6
    • 0020557001 scopus 로고
    • Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells
    • Andersson B, Dahmen J, Frejd T, Leffler H, Magnusson G, Noori G, Eden CS (1983) Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells. J Exp Med 158:559-570
    • (1983) J Exp Med , vol.158 , pp. 559-570
    • Andersson, B.1    Dahmen, J.2    Frejd, T.3    Leffler, H.4    Magnusson, G.5    Noori, G.6    Eden, C.S.7
  • 7
    • 0035190667 scopus 로고    scopus 로고
    • Airway mucus obstruction: Mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia
    • Rose MC, Nickola TJ, Voynow JA (2001) Airway mucus obstruction: mucin glycoproteins, MUC gene regulation and goblet cell hyperplasia. Am J Respir Cell Mol Biol 25:533-537
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 533-537
    • Rose, M.C.1    Nickola, T.J.2    Voynow, J.A.3
  • 10
    • 33747883766 scopus 로고    scopus 로고
    • Cell surface-associated mucins in signal transduction
    • Singh PK, Hollingsworth MA (2006) Cell surface-associated mucins in signal transduction. Trends Cell Biol 16:467-476
    • (2006) Trends Cell Biol , vol.16 , pp. 467-476
    • Singh, P.K.1    Hollingsworth, M.A.2
  • 13
    • 0035137134 scopus 로고    scopus 로고
    • Roles of O-linked oligosaccharides in immune responses
    • Tsuboi S, Fukuda M (2001) Roles of O-linked oligosaccharides in immune responses. Bioessays 23:46-53
    • (2001) Bioessays , vol.23 , pp. 46-53
    • Tsuboi, S.1    Fukuda, M.2
  • 14
    • 0029070815 scopus 로고
    • Leukocyte trafficking mediated by selectin-carbohydrate interactions
    • McEver RP, Moore KL, Cummings RD (1995) Leukocyte trafficking mediated by selectin-carbohydrate interactions. J Biol Chem 270:11025-11028
    • (1995) J Biol Chem , vol.270 , pp. 11025-11028
    • McEver, R.P.1    Moore, K.L.2    Cummings, R.D.3
  • 15
    • 0030658888 scopus 로고    scopus 로고
    • Carcinoma-associated expression of core 2 beta-1, 6-N- acetylglucosaminyltransferase gene in human colorectal cancer: Role of O-glycans in tumor progression
    • Shimodaira K, Nakayama J, Nakamura N, Hasebe O, Katsuyama T, Fukuda M (1997) Carcinoma-associated expression of core 2 beta-1, 6-N- acetylglucosaminyltransferase gene in human colorectal cancer: role of O-glycans in tumor progression. Cancer Res 57:5201-5206
    • (1997) Cancer Res , vol.57 , pp. 5201-5206
    • Shimodaira, K.1    Nakayama, J.2    Nakamura, N.3    Hasebe, O.4    Katsuyama, T.5    Fukuda, M.6
  • 16
    • 0019321948 scopus 로고
    • Mucin synthesis. II. Substrate specificity and product identification studies on canine submaxillary gland UDP-GlcNAc:Gal beta 1-3GalNAc(GlcNAc leads to GalNAc) beta 6-N-acetylglucosaminyltransferase
    • Williams D, Longmore G, Matta KL, Schachter H (1980) Mucin synthesis. II. Substrate specificity and product identification studies on canine submaxillary gland UDP-GlcNAc:Gal beta 1-3GalNAc(GlcNAc leads to GalNAc) beta 6-N-acetylglucosaminyltransferase. J Biol Chem 255:11253-11261
    • (1980) J Biol Chem , vol.255 , pp. 11253-11261
    • Williams, D.1    Longmore, G.2    Matta, K.L.3    Schachter, H.4
  • 17
    • 0021813383 scopus 로고
    • Mucin synthesis, UDP-GlcNAc: GalNAc-R beta 3-N- acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase from pig and rat colon mucosa
    • Brockhausen I, Matta KL, Orr J, Schachter H (1985) Mucin synthesis, UDP-GlcNAc: GalNAc-R beta 3-N-acetylglucosaminyltransferase and UDP-GlcNAc:GlcNAc beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 6-N- acetylglucosaminyltransferase from pig and rat colon mucosa. Biochemistry 24:1866-1874
    • (1985) Biochemistry , vol.24 , pp. 1866-1874
    • Brockhausen, I.1    Matta, K.L.2    Orr, J.3    Schachter, H.4
  • 18
    • 0022500701 scopus 로고
    • Mucin synthesis, conversion of R1-beta 1-3Gal-R2 to R1-beta 1-3(GlcNAc beta 1-6)gal-R2 and of R1-beta 1-3GalNAc-R2 to R1-beta 1-3(GlcNAc beta 1-6)GalNAc-R2 by a beta 6-N-acetylglucosaminyltransferase in pig gastric mucosa
    • Brockhausen I, Matta KL, Orr J, Schachter H, Koenderman AH, van den Eijnden DH (1986) Mucin synthesis, conversion of R1-beta 1-3Gal-R2 to R1-beta 1-3(GlcNAc beta 1-6)gal-R2 and of R1-beta 1-3GalNAc-R2 to R1-beta 1-3(GlcNAc beta 1-6)GalNAc-R2 by a beta 6-N-acetylglucosaminyltransferase in pig gastric mucosa. Eur J Biochem 157:463-474
    • (1986) Eur J Biochem , vol.157 , pp. 463-474
    • Brockhausen, I.1    Matta, K.L.2    Orr, J.3    Schachter, H.4    Koenderman, A.H.5    Van Den Eijnden, D.H.6
  • 19
    • 0026352595 scopus 로고
    • Mucin biosynthesis: Purification and characterization of a mucin beta 6N-acetylglucosaminyltransferase
    • Ropp PA, Little MR, Cheng PW (1991) Mucin biosynthesis: purification and characterization of a mucin beta 6N-acetylglucosaminyltransferase. J Biol Chem 266:23863-23871
    • (1991) J Biol Chem , vol.266 , pp. 23863-23871
    • Ropp, P.A.1    Little, M.R.2    Cheng, P.W.3
  • 20
    • 0026662007 scopus 로고
    • Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen
    • Bierhuizen MF, Fukuda M (1992) Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen. Proc Natl Acad Sci USA 89:9326-9330
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9326-9330
    • Bierhuizen, M.F.1    Fukuda, M.2
  • 21
    • 0027207613 scopus 로고
    • Expression of the developmental i antigen by a cloned human cDNA encoding a member of a beta-1, 6-N-acetylglucosaminyltransferase gene family
    • Bierhuizen MF, Mattei MG, Fukuda M (1993) Expression of the developmental I antigen by a cloned human cDNA encoding a member of a beta-1, 6-N-acetylglucosaminyltransferase gene family. Genes Dev 7:468-478
    • (1993) Genes Dev , vol.7 , pp. 468-478
    • Bierhuizen, M.F.1    Mattei, M.G.2    Fukuda, M.3
  • 22
    • 0033582478 scopus 로고    scopus 로고
    • Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1, 6-N-acetylglucosaminyltransferase forming core 2 and core 4
    • Schwientek T, Nomoto M, Levery SB, Merkx G, van Kessel AG, Bennett EP, Hollingsworth MA, Clausen H (1999) Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1, 6-N- acetylglucosaminyltransferase forming core 2 and core 4. J Biol Chem 274:4504-4512
    • (1999) J Biol Chem , vol.274 , pp. 4504-4512
    • Schwientek, T.1    Nomoto, M.2    Levery, S.B.3    Merkx, G.4    Van Kessel, A.G.5    Bennett, E.P.6    Hollingsworth, M.A.7    Clausen, H.8
  • 23
    • 0033613934 scopus 로고    scopus 로고
    • Molecular cloning and expression of a novel beta-1, 6-N-acetylglu- cosaminyltransferase that forms core 2, core 4, and i branches
    • Yeh JC, Ong E, Fukuda M (1999) Molecular cloning and expression of a novel beta-1, 6-N-acetylglu-cosaminyltransferase that forms core 2, core 4, and I branches. J Biol Chem 274:3215-3221
    • (1999) J Biol Chem , vol.274 , pp. 3215-3221
    • Yeh, J.C.1    Ong, E.2    Fukuda, M.3
  • 24
    • 0034646696 scopus 로고    scopus 로고
    • Control of O-glycan branch formation. Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n- acetylglucosaminyltransferase
    • Schwientek T, Yeh JC, Levery SB, Keck B, Merkx G, van Kessel AG, Fukuda M, Clausen H (2000) Control of O-glycan branch formation. Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n- acetylglucosaminyltransferase. J Biol Chem 275:11106-11113
    • (2000) J Biol Chem , vol.275 , pp. 11106-11113
    • Schwientek, T.1    Yeh, J.C.2    Levery, S.B.3    Keck, B.4    Merkx, G.5    Van Kessel, A.G.6    Fukuda, M.7    Clausen, H.8
  • 25
    • 0242496203 scopus 로고    scopus 로고
    • Highly conserved cysteines of mouse core 2 beta1, 6-N- acetylglucosaminyltransferase i form a network of disulfide bonds and include a thiol that affects enzyme activity
    • Yen TY, Macher BA, Bryson S, Chang X, Tvaroska I, Tse R, Takeshita S, Lew AM, Datti A (2003) Highly conserved cysteines of mouse core 2 beta1, 6-N-acetylglucosaminyltransferase I form a network of disulfide bonds and include a thiol that affects enzyme activity. J Biol Chem 278:45864-45881
    • (2003) J Biol Chem , vol.278 , pp. 45864-45881
    • Yen, T.Y.1    MacHer, B.A.2    Bryson, S.3    Chang, X.4    Tvaroska, I.5    Tse, R.6    Takeshita, S.7    Lew, A.M.8    Datti, A.9
  • 26
    • 4644219854 scopus 로고    scopus 로고
    • Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltra nsferase-M cysteines conserved in the mucin beta6-N-acetylglucosaminyltransferase family
    • Singh J, Khan GA, Kinarsky L, Cheng H, Wilken J, Choi KH, Bedows E, Sherman S, Cheng PW (2004) Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltra nsferase-M cysteines conserved in the mucin beta6-N-acetylglucosaminyltransferase family. J Biol Chem 279:38969-38977
    • (2004) J Biol Chem , vol.279 , pp. 38969-38977
    • Singh, J.1    Khan, G.A.2    Kinarsky, L.3    Cheng, H.4    Wilken, J.5    Choi, K.H.6    Bedows, E.7    Sherman, S.8    Cheng, P.W.9
  • 27
    • 0029025688 scopus 로고
    • Genomic organization of core 2 and i branching beta-1, 6-N-acetylglucosaminyltransferases. Implication for evolution of the beta-1, 6-N-acetylglucosaminyltransferase gene family
    • Bierhuizen MF, Maemura K, Kudo S, Fukuda M (1995) Genomic organization of core 2 and I branching beta-1, 6-N-acetylglucosaminyltransferases. Implication for evolution of the beta-1, 6-N-acetylglucosaminyltransferase gene family. Glycobiology 5:417-425
    • (1995) Glycobiology , vol.5 , pp. 417-425
    • Bierhuizen, M.F.1    Maemura, K.2    Kudo, S.3    Fukuda, M.4
  • 28
    • 0030763636 scopus 로고    scopus 로고
    • Tissue-specific regulation of mouse core 2 beta-1, 6-N- acetylglucosaminyltransferase
    • Sekine M, Nara K, Suzuki A (1997) Tissue-specific regulation of mouse core 2 beta-1, 6-N-acetylglucosaminyltransferase. J Biol Chem 272:27246-27252
    • (1997) J Biol Chem , vol.272 , pp. 27246-27252
    • Sekine, M.1    Nara, K.2    Suzuki, A.3
  • 29
    • 2342453352 scopus 로고    scopus 로고
    • Mucin biosynthesis: Bovine C2GnT-M gene, tissue-specific expression, and herpes virus-4 homologue
    • Choi KH, Osorio FA, Cheng PW (2004) Mucin biosynthesis: bovine C2GnT-M gene, tissue-specific expression, and herpes virus-4 homologue. Am J Respir Cell Mol Biol 30:710-719
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 710-719
    • Choi, K.H.1    Osorio, F.A.2    Cheng, P.W.3
  • 30
    • 33748756443 scopus 로고    scopus 로고
    • X-ray crystal structure of leukocyte type core 2 beta1, 6-N-acetylglucosaminyltransferase. Evidence for a convergence of metal ion-independent glycosyltransferase mechanism
    • Pak JE, Arnoux P, Zhou S, Sivarajah P, Satkunarajah M, Xing X, Rini JM (2006) X-ray crystal structure of leukocyte type core 2 beta1, 6-N-acetylglucosaminyltransferase. Evidence for a convergence of metal ion-independent glycosyltransferase mechanism. J Biol Chem 281:26693-26701
    • (2006) J Biol Chem , vol.281 , pp. 26693-26701
    • Pak, J.E.1    Arnoux, P.2    Zhou, S.3    Sivarajah, P.4    Satkunarajah, M.5    Xing, X.6    Rini, J.M.7
  • 31
    • 83455237976 scopus 로고    scopus 로고
    • Biosynthesis and function of beta 1, 6 branched mucin-type glycans
    • Wu AM (ed) Acedemic, New York
    • Beum PV, Cheng PW (2001) Biosynthesis and function of beta 1, 6 branched mucin-type glycans. In: Wu AM (ed) The molecular immunology of complex carbohydrates-2. Acedemic, New York, pp 271-312
    • (2001) The Molecular Immunology of Complex carbohydrates-2 , pp. 271-312
    • Beum, P.V.1    Cheng, P.W.2
  • 32
    • 33744799438 scopus 로고    scopus 로고
    • Mucin-type O-glycans in human colon and breast cancer: Glycody-namics and functions
    • Brockhausen I (2006) Mucin-type O-glycans in human colon and breast cancer: glycody-namics and functions. EMBO Rep 7:599-604
    • (2006) EMBO Rep , vol.7 , pp. 599-604
    • Brockhausen, I.1
  • 33
    • 0029854393 scopus 로고    scopus 로고
    • A family of UDP-GalNAc: Polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation
    • Clausen H, Bennett EP (1996) A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation. Glycobiology 6:635-646
    • (1996) Glycobiology , vol.6 , pp. 635-646
    • Clausen, H.1    Bennett, E.P.2
  • 34
    • 0027280810 scopus 로고
    • The specificity of UDP-GalNAc:Polypeptide N- acetylgalactosaminyltransferase as inferred from a database of in vivo substrates and from the in vitro glycosylation of proteins and peptides
    • Elhammer AP, Poorman RA, Brown E, Maggiora LL, Hoogerheide JG, Kezdy FJ (1993) The specificity of UDP-GalNAc:Polypeptide N- acetylgalactosaminyltransferase as inferred from a database of in vivo substrates and from the in vitro glycosylation of proteins and peptides. J Biol Chem 268:10029-10038
    • (1993) J Biol Chem , vol.268 , pp. 10029-10038
    • Elhammer, A.P.1    Poorman, R.A.2    Brown, E.3    Maggiora, L.L.4    Hoogerheide, J.G.5    Kezdy, F.J.6
  • 35
    • 0027364263 scopus 로고
    • The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:Polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues
    • Wang Y, Agrwal N, Eckhardt AE, Stevens RD, Hill RL (1993) The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:Polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues. J Biol Chem 268:22979-22983
    • (1993) J Biol Chem , vol.268 , pp. 22979-22983
    • Wang, Y.1    Agrwal, N.2    Eckhardt, A.E.3    Stevens, R.D.4    Hill, R.L.5
  • 37
    • 49749151409 scopus 로고    scopus 로고
    • Regulation of protein O-glycosylation by the endo-plasmic reticulum-localized molecular chaperone cosmc
    • Ju T, Aryal RP, Stowell CJ, Cummings RD (2008) Regulation of protein O-glycosylation by the endo-plasmic reticulum-localized molecular chaperone cosmc. J Cell Biol 182:531-542
    • (2008) J Cell Biol , vol.182 , pp. 531-542
    • Ju, T.1    Aryal, R.P.2    Stowell, C.J.3    Cummings, R.D.4
  • 38
    • 27544487771 scopus 로고    scopus 로고
    • A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules
    • Uchimura K, Gauguet JM, Singer MS, Tsay D, Kannagi R, Muramatsu T, von Andrian UH, Rosen SD (2005) A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Nat Immunol 6:1105-1113
    • (2005) Nat Immunol , vol.6 , pp. 1105-1113
    • Uchimura, K.1    Gauguet, J.M.2    Singer, M.S.3    Tsay, D.4    Kannagi, R.5    Muramatsu, T.6    Von Andrian, U.H.7    Rosen, S.D.8
  • 40
    • 0032567431 scopus 로고    scopus 로고
    • Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans. The requirement of novel beta-1, 4-galactosyl-trans-ferase IV and beta-1, 3-n-acetylglucosaminyltransferase
    • Ujita M, McAuliffe J, Schwientek T, Almeida R, Hindsgaul O, Clausen H, Fukuda M (1998) Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans. The requirement of novel beta-1, 4-galactosyl-trans-ferase IV and beta-1, 3-n-acetylglucosaminyltransferase. J Biol Chem 273:34843-34849
    • (1998) J Biol Chem , vol.273 , pp. 34843-34849
    • Ujita, M.1    McAuliffe, J.2    Schwientek, T.3    Almeida, R.4    Hindsgaul, O.5    Clausen, H.6    Fukuda, M.7
  • 41
    • 0031445110 scopus 로고    scopus 로고
    • Expression cloning of cDNA encoding a human beta-1, 3-N- acetylglucosaminyltransferase that is essential for poly-N-acetyllactosamine synthesis
    • Sasaki K, Kurata-Miura K, Ujita M, Angata K, Nakagawa S, Sekine S, Nishi T, Fukuda M (1997) Expression cloning of cDNA encoding a human beta-1, 3-N-acetylglucosaminyltransferase that is essential for poly-N-acetyllactosamine synthesis. Proc Natl Acad Sci USA 94:14294-14299
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14294-14299
    • Sasaki, K.1    Kurata-Miura, K.2    Ujita, M.3    Angata, K.4    Nakagawa, S.5    Sekine, S.6    Nishi, T.7    Fukuda, M.8
  • 42
    • 0034956687 scopus 로고    scopus 로고
    • The genetic regulation of fucosylated and sialylated antigens on developing myeloid cells
    • Wu AM (ed) Acedemic, New York
    • Watkins WM, Clarke JL (2001) The genetic regulation of fucosylated and sialylated antigens on developing myeloid cells. In: Wu AM (ed) The molecular immunology of complex car-bohydrates-2. Acedemic, New York, pp 231-265
    • (2001) The Molecular Immunology of Complex car-bohydrates-2 , pp. 231-265
    • Watkins, W.M.1    Clarke, J.L.2
  • 43
    • 0037066753 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc- peptide beta1, 3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans
    • Iwai T, Inaba N, Naundorf A, Zhang Y, Gotoh M, Iwasaki H, Kudo T, Togayachi A, Ishizuka Y, Nakanishi H, Narimatsu H (2002) Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1, 3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J Biol Chem 277:12802-12809
    • (2002) J Biol Chem , vol.277 , pp. 12802-12809
    • Iwai, T.1    Inaba, N.2    Naundorf, A.3    Zhang, Y.4    Gotoh, M.5    Iwasaki, H.6    Kudo, T.7    Togayachi, A.8    Ishizuka, Y.9    Nakanishi, H.10    Narimatsu, H.11
  • 44
    • 0036005794 scopus 로고    scopus 로고
    • The cytosolic and transmembrane domains of the beta 1, 6N-acetylglucosaminyltransferase (C2GnT) function as a cis to medial/Golgi-targeting determinant
    • Zerfaoui M, Fukuda M, Langlet C, Mathieu S, Suzuki M, Lombardo D, El-Battari A (2002) The cytosolic and transmembrane domains of the beta 1, 6N-acetylglucosaminyltransferase (C2GnT) function as a cis to medial/Golgi-targeting determinant. Glycobiology 12:15-24
    • (2002) Glycobiology , vol.12 , pp. 15-24
    • Zerfaoui, M.1    Fukuda, M.2    Langlet, C.3    Mathieu, S.4    Suzuki, M.5    Lombardo, D.6    El-Battari, A.7
  • 45
    • 0031040995 scopus 로고    scopus 로고
    • Golgi localization of glycosyltransferases: More questions than answers
    • Colley KJ (1997) Golgi localization of glycosyltransferases: more questions than answers. Glycobiology 7:1-13
    • (1997) Glycobiology , vol.7 , pp. 1-13
    • Colley, K.J.1
  • 46
    • 0037629966 scopus 로고    scopus 로고
    • Soluble human core 2 beta6-N-acetylglucosaminyltransferase C2GnT1 requires its conserved cysteine residues for full activity
    • Yang X, Qin W, Lehotay M, Toki D, Dennis P, Schutzbach JS, Brockhausen I (2003) Soluble human core 2 beta6-N-acetylglucosaminyltransferase C2GnT1 requires its conserved cysteine residues for full activity. Biochim Biophys Acta 1648:62-74
    • (2003) Biochim Biophys Acta , vol.1648 , pp. 62-74
    • Yang, X.1    Qin, W.2    Lehotay, M.3    Toki, D.4    Dennis, P.5    Schutzbach, J.S.6    Brockhausen, I.7
  • 47
    • 0035824876 scopus 로고    scopus 로고
    • Three-dimensional structures of the Mn and Mg dTDP complexes of the family GT-2 glycosyltransferase SpsA: A comparison with related NDP-sugar glycosyltrans-ferases
    • Tarbouriech N, Charnock SJ, Davies GJ (2001) Three-dimensional structures of the Mn and Mg dTDP complexes of the family GT-2 glycosyltransferase SpsA: a comparison with related NDP-sugar glycosyltrans-ferases. J Mol Biol 314:655-661
    • (2001) J Mol Biol , vol.314 , pp. 655-661
    • Tarbouriech, N.1    Charnock, S.J.2    Davies, G.J.3
  • 48
    • 0034613392 scopus 로고    scopus 로고
    • Identification of essential amino acid residues in the Sinorhizobium meliloti glucosyltransferase Exo
    • Garinot-Schneider C, Lellouch AC, Geremia RA (2000) Identification of essential amino acid residues in the Sinorhizobium meliloti glucosyltransferase Exo. J Biol Chem 275:31407-31413
    • (2000) J Biol Chem , vol.275 , pp. 31407-31413
    • Garinot-Schneider, C.1    Lellouch, A.C.2    Geremia, R.A.3
  • 49
    • 35648957730 scopus 로고    scopus 로고
    • Control of core 2 beta1, 6N-acetylglucosaminyltransferase-I transcription by Sp1 in lymphocytes and epithelial cells
    • Falkenberg VR, Fregien N (2007) Control of core 2 beta1, 6N-acetylglucosaminyltransferase-I transcription by Sp1 in lymphocytes and epithelial cells. Glycoconj J 24:511-519
    • (2007) Glycoconj J , vol.24 , pp. 511-519
    • Falkenberg, V.R.1    Fregien, N.2
  • 50
    • 34249896720 scopus 로고    scopus 로고
    • Mucin biosyn thesis: Identification of the cis-regulatory elements of human C2GnT-M gene
    • Tan S, Cheng PW (2007) Mucin biosynthesis: identification of the cis-regulatory elements of human C2GnT-M gene. Am J Respir Cell Mol Biol 36:737-745
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 737-745
    • Tan, S.1    Cheng, P.W.2
  • 51
    • 33644930051 scopus 로고    scopus 로고
    • The cis-regulatory element Gsl5 is indispensable for proximal straight tubule cell-specific transcription of core 2 beta-1, 6-N- acetylglucosaminyltransferase in the mouse kidney
    • Sekine M, Taya C, Shitara H, Kikkawa Y, Akamatsu N, Kotani M, Miyazaki M, Suzuki A, Yonekawa H (2006) The cis-regulatory element Gsl5 is indispensable for proximal straight tubule cell-specific transcription of core 2 beta-1, 6-N-acetylglucosaminyltransferase in the mouse kidney. J Biol Chem 281:1008-1015
    • (2006) J Biol Chem , vol.281 , pp. 1008-1015
    • Sekine, M.1    Taya, C.2    Shitara, H.3    Kikkawa, Y.4    Akamatsu, N.5    Kotani, M.6    Miyazaki, M.7    Suzuki, A.8    Yonekawa, H.9
  • 52
    • 0036737802 scopus 로고    scopus 로고
    • Phylogenetic development of a regulatory gene for the core 2 GlcNAc transferase in mus musculus
    • Sekine M, Kikkawa Y, Takahama S, Tsuda K, Yonekawa H, Suzuki A (2002) Phylogenetic development of a regulatory gene for the core 2 GlcNAc transferase in mus musculus. J Biochem 132:387-393
    • (2002) J Biochem , vol.132 , pp. 387-393
    • Sekine, M.1    Kikkawa, Y.2    Takahama, S.3    Tsuda, K.4    Yonekawa, H.5    Suzuki, A.6
  • 54
    • 0038280004 scopus 로고    scopus 로고
    • Multiple transcription initiation and alternative splicing in the 5' untranslated region of the core 2 beta1-6N-acetylglucosaminyl-transferase i gene
    • Falkenberg VR, Alvarez K, Roman C, Fregien N (2003) Multiple transcription initiation and alternative splicing in the 5' untranslated region of the core 2 beta1-6N-acetylglucosaminyl-transferase I gene. Glycobiology 13:411-418
    • (2003) Glycobiology , vol.13 , pp. 411-418
    • Falkenberg, V.R.1    Alvarez, K.2    Roman, C.3    Fregien, N.4
  • 55
    • 34548781311 scopus 로고    scopus 로고
    • Mucin biosyn thesis: Molecular cloning and expression of mouse mucus-type core 2 beta1, 6N-acetylglucosaminyltransferase
    • Hashimoto M, Tan S, Mori N, Cheng H, Cheng PW (2007) Mucin biosynthesis: molecular cloning and expression of mouse mucus-type core 2 beta1, 6N-acetylglucosaminyltransferase. Glycobiology 17:994-1006
    • (2007) Glycobiology , vol.17 , pp. 994-1006
    • Hashimoto, M.1    Tan, S.2    Mori, N.3    Cheng, H.4    Cheng, P.W.5
  • 57
    • 39649083397 scopus 로고    scopus 로고
    • I branching formation in erythroid differentiation is regulated by transcription factor C/EBPalpha
    • Twu YC, Chen CP, Hsieh CY, Tzeng CH, Sun CF, Wang SH, Chang MS, Yu LC (2007) I branching formation in erythroid differentiation is regulated by transcription factor C/EBPalpha. Blood 110:4526-4534
    • (2007) Blood , vol.110 , pp. 4526-4534
    • Twu, Y.C.1    Chen, C.P.2    Hsieh, C.Y.3    Tzeng, C.H.4    Sun, C.F.5    Wang, S.H.6    Chang, M.S.7    Yu, L.C.8
  • 58
    • 3042580045 scopus 로고    scopus 로고
    • A nonsense mutation in the glucosaminyl (N-acetyl) transferase 2 gene (GCNT2): Association with autosomal recessive congenital cataracts
    • Pras E, Raz J, Yahalom V, Frydman M, Garzozi HJ, Pras E, Hejtmancik JF (2004) A nonsense mutation in the glucosaminyl (N-acetyl) transferase 2 gene (GCNT2): association with autosomal recessive congenital cataracts. Invest Ophthalmol Vis Sci 45:1940-1945
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1940-1945
    • Pras, E.1    Raz, J.2    Yahalom, V.3    Frydman, M.4    Garzozi, H.J.5    Pras, E.6    Hejtmancik, J.F.7
  • 59
    • 0032428668 scopus 로고    scopus 로고
    • Core 2 oligosac-charide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation
    • Ellies LG, Tsuboi S, Petryniak B, Lowe JB, Fukuda M, Marth JD (1998) Core 2 oligosac-charide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation. Immunity 9:881-890
    • (1998) Immunity , vol.9 , pp. 881-890
    • Ellies, L.G.1    Tsuboi, S.2    Petryniak, B.3    Lowe, J.B.4    Fukuda, M.5    Marth, J.D.6
  • 60
    • 0029257527 scopus 로고
    • Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells
    • Baum LG, Pang M, Perillo NL, Wu T, Delegeane A, Uittenbogaart CH, Fukuda M, Seilhamer JJ (1995) Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells. J Exp Med 181:877-887
    • (1995) J Exp Med , vol.181 , pp. 877-887
    • Baum, L.G.1    Pang, M.2    Perillo, N.L.3    Wu, T.4    Delegeane, A.5    Uittenbogaart, C.H.6    Fukuda, M.7    Seilhamer, J.J.8
  • 61
    • 0029834552 scopus 로고    scopus 로고
    • The CD43 130-kD peripheral T-cell activation antigen is downregulated in thymic positive selection
    • Ellies LG, Tao W, Fellinger W, The HS, Ziltener HJ (1996) The CD43 130-kD peripheral T-cell activation antigen is downregulated in thymic positive selection. Blood 88:1725-1732
    • (1996) Blood , vol.88 , pp. 1725-1732
    • Ellies, L.G.1    Tao, W.2    Fellinger, W.3    The, H.S.4    Ziltener, H.J.5
  • 63
    • 0037646471 scopus 로고    scopus 로고
    • Extended core 1 and core 2 branched O-glycans differentially modulate sialyl lewis X-type L-selectin ligand activity
    • Mitoma J, Petryniak B, Hiraoka N, Yeh JC, Lowe JB, Fukuda M (2003) Extended core 1 and core 2 branched O-glycans differentially modulate sialyl lewis X-type L-selectin ligand activity. J Biol Chem 278:9953-9961
    • (2003) J Biol Chem , vol.278 , pp. 9953-9961
    • Mitoma, J.1    Petryniak, B.2    Hiraoka, N.3    Yeh, J.C.4    Lowe, J.B.5    Fukuda, M.6
  • 64
    • 0036696903 scopus 로고    scopus 로고
    • Glycosylation in the control of selectin counter-receptor structure and function
    • Lowe JB (2002) Glycosylation in the control of selectin counter-receptor structure and function. Immunol Rev 186:19-36
    • (2002) Immunol Rev , vol.186 , pp. 19-36
    • Lowe, J.B.1
  • 65
    • 0035266352 scopus 로고    scopus 로고
    • Clinicopathological significance of core 2 beta1, 6-N- acetylglucosaminyltransferase messenger RNA expressed in the pulmonary adenocarcinoma determined by in situ hybridization
    • Machida E, Nakayama J, Amano J, Fukuda M (2001) Clinicopathological significance of core 2 beta1, 6-N-acetylglucosaminyltransferase messenger RNA expressed in the pulmonary adenocarcinoma determined by in situ hybridization. Cancer Res 61:2226-2231
    • (2001) Cancer Res , vol.61 , pp. 2226-2231
    • MacHida, E.1    Nakayama, J.2    Amano, J.3    Fukuda, M.4
  • 66
    • 0034741783 scopus 로고    scopus 로고
    • Core 2 beta1, 6-N-acetylglucosaminyl-transferases and alpha1, 3-fucosyltransferases regulate the synthesis of O-glycans on selectin ligands on oral cavity carcinoma cells
    • Renkonen J, Rabina J, Mattila P, Grenman R, Renkonen R (2001) Core 2 beta1, 6-N-acetylglucosaminyl-transferases and alpha1, 3-fucosyltransferases regulate the synthesis of O-glycans on selectin ligands on oral cavity carcinoma cells. APMIS 109:500-506
    • (2001) APMIS , vol.109 , pp. 500-506
    • Renkonen, J.1    Rabina, J.2    Mattila, P.3    Grenman, R.4    Renkonen, R.5
  • 67
    • 0033609828 scopus 로고    scopus 로고
    • Expression of core 2 beta-1, 6-N-acetylglucosaminyltransferase in a human pancreatic cancer cell line results in altered expression of MUC1 tumor-associated epitopes
    • Beum PV, Singh J, Burdick M, Hollingsworth MA, Cheng PW (1999) Expression of core 2 beta-1, 6-N-acetylglucosaminyltransferase in a human pancreatic cancer cell line results in altered expression of MUC1 tumor-associated epitopes. J Biol Chem 274:24641-24648
    • (1999) J Biol Chem , vol.274 , pp. 24641-24648
    • Beum, P.V.1    Singh, J.2    Burdick, M.3    Hollingsworth, M.A.4    Cheng, P.W.5
  • 68
    • 0025851570 scopus 로고
    • Biosynthesis of O-glycans in leukocytes from normal donors and from patients with leukemia: Increase in O-glycan core 2 UDP-GlcNAc:Gal beta 3 GalNAc alpha-R (GlcNAc to GalNAc) beta(1-6)-N-acetylglucosaminyltransferase in leukemic cells
    • Brockhausen I, Kuhns W, Schachter H, Matta KL, Sutherland DR, Baker MA (1991) Biosynthesis of O-glycans in leukocytes from normal donors and from patients with leukemia: increase in O-glycan core 2 UDP-GlcNAc:Gal beta 3 GalNAc alpha-R (GlcNAc to GalNAc) beta(1-6)-N-acetylglucosaminyltransferase in leukemic cells. Cancer Res 51:1257-1263
    • (1991) Cancer Res , vol.51 , pp. 1257-1263
    • Brockhausen, I.1    Kuhns, W.2    Schachter, H.3    Matta, K.L.4    Sutherland, D.R.5    Baker, M.A.6
  • 69
    • 0027530462 scopus 로고
    • Branching beta 1-6N-acetylglucosaminetransferases and polylactosamine expression in mouse F9 teratocar-cinoma cells and differentiated counterparts
    • Heffernan M, Lotan R, Amos B, Palcic M, Takano R, Dennis JW (1993) Branching beta 1-6N-acetylglucosaminetransferases and polylactosamine expression in mouse F9 teratocar-cinoma cells and differentiated counterparts. J Biol Chem 268:1242-1251
    • (1993) J Biol Chem , vol.268 , pp. 1242-1251
    • Heffernan, M.1    Lotan, R.2    Amos, B.3    Palcic, M.4    Takano, R.5    Dennis, J.W.6
  • 70
    • 0027457979 scopus 로고
    • Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N- acetylglucosaminyltransferase (GlcNAc to GalNAc) in chinese hamster ovary cells
    • Datti A, Dennis JW (1993) Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in chinese hamster ovary cells. J Biol Chem 268:5409-5416
    • (1993) J Biol Chem , vol.268 , pp. 5409-5416
    • Datti, A.1    Dennis, J.W.2
  • 71
    • 15644377526 scopus 로고    scopus 로고
    • Single glycosyltransferase, core 2 beta1 6-N-acetylglucosami nyltransferase, regulates cell surface sialyl-lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester
    • Nakamura M, Kudo T, Narimatsu H, Furukawa Y, Kikuchi J, Asakura S, Yang W, Iwase S, Hatake K, Miura Y (1998) Single glycosyltransferase, core 2 beta1 6-N-acetylglucosami nyltransferase, regulates cell surface sialyl-lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester. J Biol Chem 273:26779-26789
    • (1998) J Biol Chem , vol.273 , pp. 26779-26789
    • Nakamura, M.1    Kudo, T.2    Narimatsu, H.3    Furukawa, Y.4    Kikuchi, J.5    Asakura, S.6    Yang, W.7    Iwase, S.8    Hatake, K.9    Miura, Y.10
  • 72
    • 0022893107 scopus 로고
    • Morphological abnormalities in the lymphocytes of patients with the wiskott-aldrich syndrome
    • Kenney D, Cairns L, Remold-O'Donnell E, Peterson J, Rosen FS, Parkman R (1986) Morphological abnormalities in the lymphocytes of patients with the wiskott-aldrich syndrome. Blood 68:1329-1332
    • (1986) Blood , vol.68 , pp. 1329-1332
    • Kenney, D.1    Cairns, L.2    Remold-O'Donnell, E.3    Peterson, J.4    Rosen, F.S.5    Parkman, R.6
  • 75
    • 0019856576 scopus 로고
    • Surface protein abnormalities in lymphocytes and platelets from patients with Wiskott-Aldrich syndrome
    • Parkman R, Remold-O'Donnell E, Kenney DM, Perrine S, Rosen FS (1981) Surface protein abnormalities in lymphocytes and platelets from patients with Wiskott-Aldrich syndrome. Lancet 2:1387-1389
    • (1981) Lancet , vol.2 , pp. 1387-1389
    • Parkman, R.1    Remold-O'Donnell, E.2    Kenney, D.M.3    Perrine, S.4    Rosen, F.S.5
  • 76
    • 0021250856 scopus 로고
    • Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome
    • Remold-O'Donnell E, Kenney DM, Parkman R, Cairns L, Savage B, Rosen FS (1984) Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome. J Exp Med 159:1705-1723
    • (1984) J Exp Med , vol.159 , pp. 1705-1723
    • Remold-O'Donnell, E.1    Kenney, D.M.2    Parkman, R.3    Cairns, L.4    Savage, B.5    Rosen, F.S.6
  • 77
    • 0025726368 scopus 로고
    • Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome
    • Park JK, Rosenstein YJ, Remold-O'Donnell E, Bierer BE, Rosen FS, Burakoff SJ (1991) Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome. Nature 350:706-709
    • (1991) Nature , vol.350 , pp. 706-709
    • Park, J.K.1    Rosenstein, Y.J.2    Remold-O'Donnell, E.3    Bierer, B.E.4    Rosen, F.S.5    Burakoff, S.J.6
  • 80
    • 0030611585 scopus 로고    scopus 로고
    • Activity levels of a beta1, 6N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients
    • Orlacchio A, Sarchielli P, Gallai V, Datti A, Saccardi C, Palmerini CA (1997) Activity levels of a beta1, 6N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients. J Neurol Sci 151:177-183
    • (1997) J Neurol Sci , vol.151 , pp. 177-183
    • Orlacchio, A.1    Sarchielli, P.2    Gallai, V.3    Datti, A.4    Saccardi, C.5    Palmerini, C.A.6
  • 82
    • 0033499812 scopus 로고    scopus 로고
    • Circulating antibodies against an exocrine pancreatic enzyme in type 1 diabetes
    • Panicot L, Mas E, Thivolet C, Lombardo D (1999) Circulating antibodies against an exocrine pancreatic enzyme in type 1 diabetes. Diabetes 48:2316-2323
    • (1999) Diabetes , vol.48 , pp. 2316-2323
    • Panicot, L.1    Mas, E.2    Thivolet, C.3    Lombardo, D.4
  • 83
    • 0023803332 scopus 로고
    • Human T-lymphocyte activation is associated with changes in O-glycan biosynthesis
    • Piller F, Piller V, Fox RI, Fukuda M (1988) Human T-lymphocyte activation is associated with changes in O-glycan biosynthesis. J Biol Chem 263:15146-15150
    • (1988) J Biol Chem , vol.263 , pp. 15146-15150
    • Piller, F.1    Piller, V.2    Fox, R.I.3    Fukuda, M.4
  • 84
    • 33750982692 scopus 로고    scopus 로고
    • Roles of mucin-type O-glycans synthesized by core2beta1, 6-N-acetylglucosaminyltransferase
    • Fukuda M (2006) Roles of mucin-type O-glycans synthesized by core2beta1, 6-N-acetylglucosaminyltransferase. Methods Enzymol 416:332-346
    • (2006) Methods Enzymol , vol.416 , pp. 332-346
    • Fukuda, M.1
  • 85
    • 0035877986 scopus 로고    scopus 로고
    • Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice
    • Sperandio M, Thatte A, Foy D, Ellies LG, Marth JD, Ley K (2001) Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase- deficient mice. Blood 97:3812-3819
    • (2001) Blood , vol.97 , pp. 3812-3819
    • Sperandio, M.1    Thatte, A.2    Foy, D.3    Ellies, L.G.4    Marth, J.D.5    Ley, K.6
  • 86
    • 0017815793 scopus 로고
    • Cell surface glycoproteins of murine cytotoxic T lymphocytes. I. T 145, a new cell surface glycoprotein selectively expressed on Ly 1-2+ cytotoxic T lymphocytes
    • Kimura AK, Wigzell H (1978) Cell surface glycoproteins of murine cytotoxic T lymphocytes. I. T 145, a new cell surface glycoprotein selectively expressed on Ly 1-2+ cytotoxic T lymphocytes. J Exp Med 147:1418-1434
    • (1978) J Exp Med , vol.147 , pp. 1418-1434
    • Kimura, A.K.1    Wigzell, H.2
  • 89
    • 33750352830 scopus 로고    scopus 로고
    • CD43 deficiency has no impact in competitive in vivo assays of neutrophil or activated T cell recruitment efficiency
    • Carlow DA, Ziltener HJ (2006) CD43 deficiency has no impact in competitive in vivo assays of neutrophil or activated T cell recruitment efficiency. J Immunol 177:6450-6459
    • (2006) J Immunol , vol.177 , pp. 6450-6459
    • Carlow, D.A.1    Ziltener, H.J.2
  • 90
    • 0036771571 scopus 로고    scopus 로고
    • Beta-galactoside alpha2, 3-sialyltransferase-I gene expression during Th2 but not Th1 differentiation: Implications for core2-glycan formation on cell surface proteins
    • Grabie N, Delfs MW, Lim YC, Westrich JR, Luscinskas FW, Lichtman AH (2002) Beta-galactoside alpha2, 3-sialyltransferase-I gene expression during Th2 but not Th1 differentiation: implications for core2-glycan formation on cell surface proteins. Eur J Immunol 32:2766-2772
    • (2002) Eur J Immunol , vol.32 , pp. 2766-2772
    • Grabie, N.1    Delfs, M.W.2    Lim, Y.C.3    Westrich, J.R.4    Luscinskas, F.W.5    Lichtman, A.H.6
  • 91
    • 0031052022 scopus 로고    scopus 로고
    • Modification of CD43 and other lymphocyte O-glycoproteins by core 2N-acetylglucosaminyltransferase
    • Barran P, Fellinger W, Warren CE, Dennis JW, Ziltener HJ (1997) Modification of CD43 and other lymphocyte O-glycoproteins by core 2N-acetylglucosaminyltransferase. Glycobiology 7:129-136
    • (1997) Glycobiology , vol.7 , pp. 129-136
    • Barran, P.1    Fellinger, W.2    Warren, C.E.3    Dennis, J.W.4    Ziltener, H.J.5
  • 92
    • 14844290268 scopus 로고    scopus 로고
    • Not core 2 beta 1, 6-N-acetylglucosaminyltransferase-2 or -3 but-1 regulates sialyl-Lewis x expression in human precursor B cells
    • Kikuchi J, Shinohara H, Nonomura C, Ando H, Takaku S, Nojiri H, Nakamura M (2005) Not core 2 beta 1, 6-N-acetylglucosaminyltransferase-2 or -3 but-1 regulates sialyl-Lewis x expression in human precursor B cells. Glycobiology 15:271-280
    • (2005) Glycobiology , vol.15 , pp. 271-280
    • Kikuchi, J.1    Shinohara, H.2    Nonomura, C.3    Ando, H.4    Takaku, S.5    Nojiri, H.6    Nakamura, M.7
  • 93
    • 0023008168 scopus 로고
    • Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelog-enous leukemia cells
    • Fukuda M, Carlsson SR, Klock JC, Dell A (1986) Structures of O-linked oligosaccharides isolated from normal granulocytes, chronic myelogenous leukemia cells, and acute myelog-enous leukemia cells. J Biol Chem 261:12796-12806
    • (1986) J Biol Chem , vol.261 , pp. 12796-12806
    • Fukuda, M.1    Carlsson, S.R.2    Klock, J.C.3    Dell, A.4
  • 94
    • 0026489530 scopus 로고
    • Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans
    • Maemura K, Fukuda M (1992) Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans. J Biol Chem 267: 24379-24386
    • (1992) J Biol Chem , vol.267 , pp. 24379-24386
    • Maemura, K.1    Fukuda, M.2
  • 95
    • 0033373335 scopus 로고    scopus 로고
    • Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration
    • Yang J, Hirata T, Croce K, Merrill-Skoloff G, Tchernychev B, Williams E, Flaumenhaft R, Furie BC, Furie B (1999) Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration. J Exp Med 190:1769-1782
    • (1999) J Exp Med , vol.190 , pp. 1769-1782
    • Yang, J.1    Hirata, T.2    Croce, K.3    Merrill-Skoloff, G.4    Tchernychev, B.5    Williams, E.6    Flaumenhaft, R.7    Furie, B.C.8    Furie, B.9
  • 98
    • 0141756182 scopus 로고    scopus 로고
    • Glycan-dependent leukocyte adhesion and recruitment in inflammation
    • Lowe JB (2003) Glycan-dependent leukocyte adhesion and recruitment in inflammation. Curr Opin Cell Biol 15:531-538
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 531-538
    • Lowe, J.B.1
  • 99
    • 0028197560 scopus 로고
    • Monospecific and common glycoprotein ligands for E-and P-selectin on myeloid cells
    • Lenter M, Levinovitz A, Isenmann S, Vestweber D (1994) Monospecific and common glycoprotein ligands for E-and P-selectin on myeloid cells. J Cell Biol 125:471-481
    • (1994) J Cell Biol , vol.125 , pp. 471-481
    • Lenter, M.1    Levinovitz, A.2    Isenmann, S.3    Vestweber, D.4
  • 100
    • 0035887765 scopus 로고    scopus 로고
    • IL-12, STAT4-dependent up-regulation of CD4(+) T cell core 2 beta-1, 6-n-acetylglucosami-nyltransferase, an enzyme essential for biosynthesis of P-selectin ligands
    • Lim YC, Xie H, Come CE, Alexander SI, Grusby MJ, Lichtman AH, Luscinskas FW (2001) IL-12, STAT4-dependent up-regulation of CD4(+) T cell core 2 beta-1, 6-n-acetylglucosami-nyltransferase, an enzyme essential for biosynthesis of P-selectin ligands. J Immunol 167:4476-4484
    • (2001) J Immunol , vol.167 , pp. 4476-4484
    • Lim, Y.C.1    Xie, H.2    Come, C.E.3    Alexander, S.I.4    Grusby, M.J.5    Lichtman, A.H.6    Luscinskas, F.W.7
  • 101
    • 0026494476 scopus 로고
    • Platelets and cancer metastasis: A causal relationship?
    • Honn KV, Tang DG, Crissman JD (1992) Platelets and cancer metastasis: a causal relationship? Cancer Metastasis Rev 11:325-351
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 325-351
    • Honn, K.V.1    Tang, D.G.2    Crissman, J.D.3
  • 102
    • 0019820999 scopus 로고
    • Role of platelets in tumor cell metastases
    • Karpatkin S, Pearlstein E (1981) Role of platelets in tumor cell metastases. Ann Intern Med 95:636-641
    • (1981) Ann Intern Med , vol.95 , pp. 636-641
    • Karpatkin, S.1    Pearlstein, E.2
  • 103
    • 1642576028 scopus 로고    scopus 로고
    • Core 2 branching beta1, 6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing
    • Hiraoka N, Kawashima H, Petryniak B, Nakayama J, Mitoma J, Marth JD, Lowe JB, Fukuda M (2004) Core 2 branching beta1, 6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing. J Biol Chem 279:3058-3067
    • (2004) J Biol Chem , vol.279 , pp. 3058-3067
    • Hiraoka, N.1    Kawashima, H.2    Petryniak, B.3    Nakayama, J.4    Mitoma, J.5    Marth, J.D.6    Lowe, J.B.7    Fukuda, M.8
  • 105
    • 2542459194 scopus 로고    scopus 로고
    • Functional analysis of the combined role of the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase and dimerization of P-selectin glycoprotein ligand-1 in rolling on P-selectin
    • Smith MJ, Smith BR, Lawrence MB, Snapp KR (2004) Functional analysis of the combined role of the O-linked branching enzyme core 2 beta1-6-N- glucosaminyltransferase and dimerization of P-selectin glycoprotein ligand-1 in rolling on P-selectin. J Biol Chem 279:21984-21991
    • (2004) J Biol Chem , vol.279 , pp. 21984-21991
    • Smith, M.J.1    Smith, B.R.2    Lawrence, M.B.3    Snapp, K.R.4
  • 106
    • 0030041932 scopus 로고    scopus 로고
    • Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P-and E-selectin
    • Li F, Wilkins PP, Crawley S, Weinstein J, Cummings RD, McEver RP (1996) Post-translational modifications of recombinant P-selectin glycoprotein ligand-1 required for binding to P-and E-selectin. J Biol Chem 271:3255-3264
    • (1996) J Biol Chem , vol.271 , pp. 3255-3264
    • Li, F.1    Wilkins, P.P.2    Crawley, S.3    Weinstein, J.4    Cummings, R.D.5    McEver, R.P.6
  • 107
    • 0029830192 scopus 로고    scopus 로고
    • Core2 beta-1, 6-N-acetylglucosaminyl-transferase enzyme activity is critical for P-selectin glycoprotein ligand-1 binding to P-selectin
    • Kumar R, Camphausen RT, Sullivan FX, Cumming DA (1996) Core2 beta-1, 6-N-acetylglucosaminyl-transferase enzyme activity is critical for P-selectin glycoprotein ligand-1 binding to P-selectin. Blood 88:3872-3879
    • (1996) Blood , vol.88 , pp. 3872-3879
    • Kumar, R.1    Camphausen, R.T.2    Sullivan, F.X.3    Cumming, D.A.4
  • 109
    • 27744552385 scopus 로고    scopus 로고
    • N-glycans of core2 beta(1,6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of alpha(1, 3)-fuco-syltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): Effects on P-, L-and E-selectin binding
    • Prorok-Hamon M, Notel F, Mathieu S, Langlet C, Fukuda M, El-Battari A (2005) N-glycans of core2 beta(1, 6)-N-acetylglucosaminyltransferase-I (C2GnT-I) but not those of alpha(1, 3)-fuco-syltransferase-VII (FucT-VII) are required for the synthesis of functional P-selectin glycoprotein ligand-1 (PSGL-1): effects on P-, L-and E-selectin binding. Biochem J 391:491-502
    • (2005) Biochem J , vol.391 , pp. 491-502
    • Prorok-Hamon, M.1    Notel, F.2    Mathieu, S.3    Langlet, C.4    Fukuda, M.5    El-Battari, A.6
  • 110
    • 27644478752 scopus 로고    scopus 로고
    • Transfection ofantisensecore 2 beta1, 6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells
    • Kikuchi J, Ozaki H, Nonomura C, Shinohara H, Iguchi S, Nojiri H, Hamada H, Kiuchi A, NakamuraM (2005) Transfection ofantisensecore 2 beta1, 6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells. Leukemia 19:1934-1940
    • (2005) Leukemia , vol.19 , pp. 1934-1940
    • Kikuchi, J.1    Ozaki, H.2    Nonomura, C.3    Shinohara, H.4    Iguchi, S.5    Nojiri, H.6    Hamada, H.7    Nakamuram, K.A.8
  • 112
  • 115
    • 33744799438 scopus 로고    scopus 로고
    • Mucin-type O-glycans in human colon and breast cancer: Glycody-namics and functions
    • Brockhausen I (2006) Mucin-type O-glycans in human colon and breast cancer: glycody-namics and functions. EMBO Rep 7:599-604
    • (2006) EMBO Rep , vol.7 , pp. 599-604
    • Brockhausen, I.1
  • 116
    • 0033559260 scopus 로고    scopus 로고
    • Dual roles of sialyl Lewis x oligosaccharides in tumor metastasis and rejection by natural killer cells
    • Ohyama C, Tsuboi S, Fukuda M (1999) Dual roles of sialyl Lewis x oligosaccharides in tumor metastasis and rejection by natural killer cells. EMBO J 18:1516-1525
    • (1999) EMBO J , vol.18 , pp. 1516-1525
    • Ohyama, C.1    Tsuboi, S.2    Fukuda, M.3
  • 117
    • 0025917249 scopus 로고
    • A carbohydrate domain common to both sialyl Le(a) and sialyl Le(x) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1
    • Berg EL, Robinson MK, Mansson O, Butcher EC, Magnani JL (1991) A carbohydrate domain common to both sialyl Le(a) and sialyl Le(x) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1. J Biol Chem 266:14869-14872
    • (1991) J Biol Chem , vol.266 , pp. 14869-14872
    • Berg, E.L.1    Robinson, M.K.2    Mansson, O.3    Butcher, E.C.4    Magnani, J.L.5
  • 119
    • 0030811894 scopus 로고    scopus 로고
    • Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer
    • Kannagi R (1997) Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer. Glycoconj J 14:577-584
    • (1997) Glycoconj J , vol.14 , pp. 577-584
    • Kannagi, R.1
  • 123
    • 0032482987 scopus 로고    scopus 로고
    • P-selectin deficiency attenuates tumor growth and metastasis
    • Kim YJ, Borsig L, Varki NM, Varki A (1998) P-selectin deficiency attenuates tumor growth and metastasis. Proc Natl Acad Sci USA 95:9325-9330
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9325-9330
    • Kim, Y.J.1    Borsig, L.2    Varki, N.M.3    Varki, A.4
  • 124
    • 0035957362 scopus 로고    scopus 로고
    • L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis
    • Qian F, Hanahan D, Weissman IL (2001) L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis. Proc Natl Acad Sci USA 98:3976-3981
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3976-3981
    • Qian, F.1    Hanahan, D.2    Weissman, I.L.3
  • 125
    • 33749363387 scopus 로고    scopus 로고
    • Haploinsufficiency of C2GnT-I glycosyltransferase renders T lymphoma cells resistant to cell death
    • Cabrera PV, Amano M, Mitoma J, Chan J, Said J, Fukuda M, Baum LG (2006) Haploinsufficiency of C2GnT-I glycosyltransferase renders T lymphoma cells resistant to cell death. Blood 108:2399-2406
    • (2006) Blood , vol.108 , pp. 2399-2406
    • Cabrera, P.V.1    Amano, M.2    Mitoma, J.3    Chan, J.4    Said, J.5    Fukuda, M.6    Baum, L.G.7
  • 126
    • 25144450137 scopus 로고    scopus 로고
    • Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis
    • Xia B, Royall JA, Damera G, Sachdev GP, Cummings RD (2005) Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis. Glycobiology 15:747-775
    • (2005) Glycobiology , vol.15 , pp. 747-775
    • Xia, B.1    Royall, J.A.2    Damera, G.3    Sachdev, G.P.4    Cummings, R.D.5
  • 128
    • 0019333793 scopus 로고
    • A new O-glycosidically linked tri-hexosamine core structure in sheep gastric mucin: A preliminary note
    • Hounsell EF, Fukuda M, Powell ME, Feizi T, Hakomori S (1980) A new O-glycosidically linked tri-hexosamine core structure in sheep gastric mucin: a preliminary note. Biochem Biophys Res Commun 92:1143-1150
    • (1980) Biochem Biophys Res Commun , vol.92 , pp. 1143-1150
    • Hounsell, E.F.1    Fukuda, M.2    Powell, M.E.3    Feizi, T.4    Hakomori, S.5
  • 129
    • 34250378697 scopus 로고    scopus 로고
    • Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
    • An G, Wei B, Xia B, McDaniel JM, Ju T, Cummings RD, Braun J, Xia L (2007) Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med 204:1417-1429
    • (2007) J Exp Med , vol.204 , pp. 1417-1429
    • An, G.1    Wei, B.2    Xia, B.3    McDaniel, J.M.4    Ju, T.5    Cummings, R.D.6    Braun, J.7    Xia, L.8
  • 130
    • 11844303459 scopus 로고    scopus 로고
    • Detection of glycosyltransferases in the golden hamster (Mesocricetus auratus) oviduct and evidence for the regulation of O-glycan biosynthesis during the estrous cycle
    • McBride DS, Brockhausen I, Kan FW (2005) Detection of glycosyltransferases in the golden hamster (Mesocricetus auratus) oviduct and evidence for the regulation of O-glycan biosynthesis during the estrous cycle. Biochim Biophys Acta 1721:107-115
    • (2005) Biochim Biophys Acta , vol.1721 , pp. 107-115
    • McBride, D.S.1    Brockhausen, I.2    Kan, F.W.3
  • 131
    • 11144335891 scopus 로고    scopus 로고
    • Mucin biosyn thesis: Upregulation of core 2 beta 1, 6N- acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line
    • Beum PV, Basma H, Bastola DR, Cheng PW (2005) Mucin biosynthesis: upregulation of core 2 beta 1, 6N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line. Am J Physiol Lung Cell Mol Physiol 288:L116-L124
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288
    • Beum, P.V.1    Basma, H.2    Bastola, D.R.3    Cheng, P.W.4
  • 132
    • 0037789219 scopus 로고    scopus 로고
    • Mucin biosynthesis: Epidermal growth factor downregulates core 2 enzymes in a human airway adenocarcinoma cell line
    • Beum PV, Bastola DR, Cheng PW (2003) Mucin biosynthesis: epidermal growth factor downregulates core 2 enzymes in a human airway adenocarcinoma cell line. Am J Respir Cell Mol Biol 29:48-56
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 48-56
    • Beum, P.V.1    Bastola, D.R.2    Cheng, P.W.3
  • 133
    • 0035879351 scopus 로고    scopus 로고
    • Cutting edge: Differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells
    • White SJ, Underhill GH, Kaplan MH, Kansas GS (2001) Cutting edge: differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells. J Immunol 167:628-631
    • (2001) J Immunol , vol.167 , pp. 628-631
    • White, S.J.1    Underhill, G.H.2    Kaplan, M.H.3    Kansas, G.S.4
  • 134
    • 18744369058 scopus 로고    scopus 로고
    • Regulation of sialyl-lewis x epitope expression by TNF-alpha and EGF in an airway carcinoma cell line
    • Ishibashi Y, Inouye Y, Okano T, Taniguchi A (2005) Regulation of sialyl-lewis x epitope expression by TNF-alpha and EGF in an airway carcinoma cell line. Glycoconj J 22:53-62
    • (2005) Glycoconj J , vol.22 , pp. 53-62
    • Ishibashi, Y.1    Inouye, Y.2    Okano, T.3    Taniguchi, A.4
  • 135
    • 1642335478 scopus 로고    scopus 로고
    • Effect ofN-acetylglucosaminyltransferase v on the expressions of other glycosyltransferases
    • Guo P, Zhang Y,ShenZH, Zhang XY, Chen HL(2004)Effect ofN- acetylglucosaminyltransferase V on the expressions of other glycosyltransferases. FEBS Lett 562:93-98
    • (2004) FEBS Lett , vol.562 , pp. 93-98
    • Guo, P.1    Zhang, Y.2    Zh, S.3    Zhang, X.Y.4    Chen, H.L.5
  • 136
    • 34250181367 scopus 로고    scopus 로고
    • Butyrate induces sLex synthesis by stimulation of selective glycosyltransferase genes
    • Radhakrishnan P, Beum PV, Tan S, Cheng PW (2007) Butyrate induces sLex synthesis by stimulation of selective glycosyltransferase genes. Biochem Biophys Res Commun 359:457-462
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 457-462
    • Radhakrishnan, P.1    Beum, P.V.2    Tan, S.3    Cheng, P.W.4
  • 137
    • 0035145798 scopus 로고    scopus 로고
    • Lipopolysaccharide induces mucus cell metaplasia in mouse lung
    • Yanagihara K, Seki M, Cheng PW (2001) Lipopolysaccharide induces mucus cell metaplasia in mouse lung. Am J Respir Cell Mol Biol 24:66-73
    • (2001) Am J Respir Cell Mol Biol , vol.24 , pp. 66-73
    • Yanagihara, K.1    Seki, M.2    Cheng, P.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.