The Relative Activities of the C2GnT1 and ST3Gal-I Glycosyltransferases Determine O-Glycan Structure and Expression of a Tumor-associated Epitope on MUC1

Journal of Biological Chemistry

Volumn 276, Issue 14, 2001, Pages 11007-11015

  Dalziel, Martin ^a   Whitehouse, Caroline ^a   McFarlane, Ian ^a   Brockhausen, Inka ^b   Gschmeissner, Stephen ^c   Schwientek, Tilo ^d   Clausen, Henrik ^d   Burchell, Joy M ^a   Taylor Papadimitriou, Joyce ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b QUEEN S UNIVERSITY   (Canada)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYMES; TISSUE; TUMORS;

GLYCOSYLATION; RELATIVE ACTIVITIES;

BIOCHEMISTRY;

EPITOPE; GALACTOSE; GLYCAN; GLYCOSYLTRANSFERASE; MUCIN 1; N ACETYLGALACTOSAMINE; N ACETYLGLUCOSAMINE; PROTEIN C2GNT1; PROTEIN ST3GA1 I; SIALIC ACID; UNCLASSIFIED DRUG; BETA 1,3 GALACTOSYL O GLYCOSYL GLYCOPROTEIN BETA 1,6 ACETYLGLUCOSAMINYL TRANSFERASE; BETA GALACTOSIDE ALPHA 2,3 SIALYLTRANSFERASE; BETA-1,3-GALACTOSYL-O-GLYCOSYL-GLYCOPROTEIN BETA-1,6-ACETYLGLUCOSAMINYL TRANSFERASE; BETA-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE; CA 15-3 ANTIGEN; N ACETYLGLUCOSAMINYLTRANSFERASE; SIALYLTRANSFERASE;

ARTICLE; BREAST; BREAST CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; GLYCOSYLATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; BREAST TUMOR; CELL CULTURE; ENZYME ACTIVATION; EPITOPE MAPPING; FEMALE; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS;

BREAST NEOPLASMS; CA-15-3 ANTIGEN; ENZYME ACTIVATION; EPITOPE MAPPING; FEMALE; HUMANS; MOLECULAR SEQUENCE DATA; N-ACETYLGLUCOSAMINYLTRANSFERASES; SIALYLTRANSFERASES; TUMOR CELLS, CULTURED;

EID: 0035815609     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006523200     Document Type: Article

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