Restoration of defective L-type Ca 2+ current in cardiac myocytes of type 2 diabetic db/db mice by Akt and PKC-ι

Journal of Cardiovascular Pharmacology

Volumn 58, Issue 4, 2011, Pages 439-445

  Lu, Zhongju ^a   Ballou, Lisa M ^b   Jiang, Ya Ping ^b   Cohen, Ira S ^a   Lin, Richard Z ^a,b,c  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Akt; cardiac myocytes; diabetes; L type Ca 2+ current; phosphoinositide 3 kinase (PI3K); PKC

Indexed keywords

CALCIUM CHANNEL L TYPE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN KINASE C IOTA; PROTEIN KINASE C LAMBDA;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL DENSITY; CONTROLLED STUDY; HEART MUSCLE CELL; HOMEOSTASIS; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; STEADY STATE; WHOLE CELL; WILD TYPE;

ANIMALS; CALCIUM CHANNELS, L-TYPE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; HUMANS; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 80053947663     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318228e68c     Document Type: Article

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