메뉴 건너뛰기




Volumn 10, Issue 10, 2011, Pages 1818-1828

A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ARACHIDONOYL DOPAMINE; EMETINE; ENDOCANNABINOID; GLUTAMINE; HEPARIN; OLEOYLDOPAMINE; PALMITOYL DOPAMINE; STREPTOMYCIN; UNCLASSIFIED DRUG;

EID: 80053936719     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-11-0268     Document Type: Article
Times cited : (70)

References (49)
  • 4
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • DOI 10.1016/j.ccr.2006.03.030, PII S1535610806001176
    • Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006;9:391-403. (Pubitemid 43668737)
    • (2006) Cancer Cell , vol.9 , Issue.5 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3    Li, A.4    Su, Q.5    Donin, N.M.6    Pastorino, S.7    Purow, B.W.8    Christopher, N.9    Zhang, W.10    Park, J.K.11    Fine, H.A.12
  • 5
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • DOI 10.1038/nature05236, PII NATURE05236
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006;444:756-60. (Pubitemid 44949604)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 9
    • 66049085403 scopus 로고    scopus 로고
    • Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
    • Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell 2009;4:568-80.
    • (2009) Cell Stem Cell , vol.4 , pp. 568-580
    • Pollard, S.M.1    Yoshikawa, K.2    Clarke, I.D.3    Danovi, D.4    Stricker, S.5    Russell, R.6
  • 12
  • 13
    • 0032566430 scopus 로고    scopus 로고
    • 9-Tetrahydrocannabinol induces apoptosis in C6 glioma cells
    • DOI 10.1016/S0014-5793(98)01085-0, PII S0014579398010850
    • Sanchez C, Galve-Roperh I, Canova C, Brachet P, Guzman M. Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. FEBS Lett 1998;436:6-10. (Pubitemid 28454597)
    • (1998) FEBS Letters , vol.436 , Issue.1 , pp. 6-10
    • Sanchez, C.1    Galve-Roperh, I.2    Canova, C.3    Brachet, P.4    Guzman, M.5
  • 14
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • DOI 10.1038/73171
    • Galve-Roperh I, Sanchez C, Cortes ML, Gomez del Pulgar T, Izquierdo M, Guzman M. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat Med 2000;6:313-9. (Pubitemid 30148624)
    • (2000) Nature Medicine , vol.6 , Issue.3 , pp. 313-319
    • Galve-Roperh, I.1    Sanchez, C.2    Cortes, M.L.3    Del, P.T.G.4    Izquierdo, M.5    Guzman, M.6
  • 16
    • 0035200613 scopus 로고    scopus 로고
    • Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors
    • Jacobsson SO, Wallin T, Fowler CJ. Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors. J Pharmacol Exp Ther 2001;299:951-9. (Pubitemid 33104965)
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.299 , Issue.3 , pp. 951-959
    • Jacobsson, S.O.P.1    Wallin, T.2    Fowler, C.J.3
  • 17
    • 0042431524 scopus 로고    scopus 로고
    • Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: Variability in response and involvement of arachidonic acid
    • DOI 10.1016/S0006-2952(03)00392-7
    • Fowler CJ, Jonsson KO, Andersson A, Juntunen J, Jarvinen T, Vandevoorde S, et al. Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. Biochem Pharmacol 2003;66:757-67. (Pubitemid 37011414)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.5 , pp. 757-767
    • Fowler, C.J.1    Jonsson, K.-O.2    Andersson, A.3    Juntunen, J.4    Jarvinen, T.5    Vandevoorde, S.6    Lambert, D.M.7    Jerman, J.C.8    Smart, D.9
  • 19
    • 45549093647 scopus 로고    scopus 로고
    • Survival of the fittest: Cancer stem cells in therapeutic resistance and angiogenesis
    • Eyler CE, Rich JN. Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis. J Clin Oncol 2008;26:2839-45.
    • (2008) J Clin Oncol , vol.26 , pp. 2839-2845
    • Eyler, C.E.1    Rich, J.N.2
  • 21
    • 65349115320 scopus 로고    scopus 로고
    • SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
    • Son MJ, Woolard K, Nam DH, Lee J, Fine HA. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 2009;4:440-52.
    • (2009) Cell Stem Cell , vol.4 , pp. 440-452
    • Son, M.J.1    Woolard, K.2    Nam, D.H.3    Lee, J.4    Fine, H.A.5
  • 26
    • 48749114753 scopus 로고    scopus 로고
    • Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas
    • Joo KM, Kim SY, Jin X, Song SY, Kong DS, Lee JI, et al. Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas. Lab Invest 2008;88:808-15.
    • (2008) Lab Invest , vol.88 , pp. 808-815
    • Joo, K.M.1    Kim, S.Y.2    Jin, X.3    Song, S.Y.4    Kong, D.S.5    Lee, J.I.6
  • 28
    • 41749118669 scopus 로고    scopus 로고
    • Identification of A2B5+CD133- Tumor-initiating cells in adult human gliomas
    • discussion 514-5
    • Ogden AT, Waziri AE, Lochhead RA, Fusco D, Lopez K, Ellis JA, et al. Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas. Neurosurgery 2008;62:505-14; discussion 514-5.
    • (2008) Neurosurgery , vol.62 , pp. 505-514
    • Ogden, A.T.1    Waziri, A.E.2    Lochhead, R.A.3    Fusco, D.4    Lopez, K.5    Ellis, J.A.6
  • 29
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Network CGAR
    • Network CGAR. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455: 1061-8.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 31
    • 70849122697 scopus 로고    scopus 로고
    • Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
    • Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One 2009;4:e7752.
    • (2009) PLoS One , vol.4
    • Brennan, C.1    Momota, H.2    Hambardzumyan, D.3    Ozawa, T.4    Tandon, A.5    Pedraza, A.6
  • 32
    • 34648821254 scopus 로고    scopus 로고
    • Making a tumour's bed: Glioblastoma stem cells and the vascular niche
    • DOI 10.1038/nrc2246, PII NRC2246
    • Gilbertson RJ, Rich JN. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat Rev Cancer 2007;7:733-6. (Pubitemid 47463683)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.10 , pp. 733-736
    • Gilbertson, R.J.1    Rich, J.N.2
  • 34
    • 77957048585 scopus 로고    scopus 로고
    • Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation
    • Panosyan EH, Laks DR, Masterman-Smith M, Mottahedeh J, Yong WH, Cloughesy TF, et al. Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation. Pediatr Blood Cancer 2010;55:644-51.
    • (2010) Pediatr Blood Cancer , vol.55 , pp. 644-651
    • Panosyan, E.H.1    Laks, D.R.2    Masterman-Smith, M.3    Mottahedeh, J.4    Yong, W.H.5    Cloughesy, T.F.6
  • 38
    • 5044224775 scopus 로고    scopus 로고
    • DNA-microarray analysis of brain cancer: Molecular classification for therapy
    • DOI 10.1038/nrn1518
    • Mischel PS, Cloughesy TF, Nelson SF. DNA-microarray analysis of brain cancer: molecular classification for therapy. Nat Rev Neurosci 2004;5:782-92. (Pubitemid 39336215)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.10 , pp. 782-792
    • Mischel, P.S.1    Cloughesy, T.F.2    Nelson, S.F.3
  • 40
    • 38049090322 scopus 로고    scopus 로고
    • Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells
    • Nakano I, Masterman-Smith M, Saigusa K, Paucar AA, Horvath S, Shoemaker L, et al. Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. J Neurosci Res 2008;86:48-60.
    • (2008) J Neurosci Res , vol.86 , pp. 48-60
    • Nakano, I.1    Masterman-Smith, M.2    Saigusa, K.3    Paucar, A.A.4    Horvath, S.5    Shoemaker, L.6
  • 42
    • 0031052014 scopus 로고    scopus 로고
    • The protein kinase c inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase
    • DOI 10.1016/S0014-5793(96)01510-4, PII S0014579396015104
    • Alessi DR. The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase. FEBS Lett 1997;402:121-3. (Pubitemid 27078242)
    • (1997) FEBS Letters , vol.402 , Issue.2-3 , pp. 121-123
    • Alessi, D.R.1
  • 45
    • 0942287672 scopus 로고    scopus 로고
    • The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase
    • DOI 10.1046/j.1471-4159.2003.02165.x
    • Won JS, Im YB, Khan M, Singh AK, Singh I. The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase. J Neurochem 2004;88:583-93. (Pubitemid 38140203)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.3 , pp. 583-593
    • Won, J.-S.1    Im, Y.-B.2    Khan, M.3    Singh, A.K.4    Singh, I.5
  • 46
    • 0036320424 scopus 로고    scopus 로고
    • Ceramide-induced apoptosis of D283 medulloblastoma cells requires mitochondrial respiratory chain activity but occurs independently of caspases and is not sensitive to Bcl-xL overexpression
    • DOI 10.1046/j.1471-4159.2002.01007.x
    • Poppe M, Reimertz C, Munstermann G, Kogel D, Prehn JH. Ceramide-induced apoptosis of D283 medulloblastoma cells requires mitochondrial respiratory chain activity but occurs independently of caspases and is not sensitive to Bcl-xL overexpression. J Neurochem 2002;82: 482-94. (Pubitemid 34831489)
    • (2002) Journal of Neurochemistry , vol.82 , Issue.3 , pp. 482-494
    • Poppe, M.1    Reimertz, C.2    Munstermann, G.3    Kogel, D.4    Prehn, J.H.M.5
  • 47
    • 33644505182 scopus 로고    scopus 로고
    • Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway
    • Habermehl D, Kammerer B, Handrick R, Eldh T, Gruber C, Cordes N, et al. Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway. BMC Cancer 2006;6:14.
    • (2006) BMC Cancer , vol.6 , pp. 14
    • Habermehl, D.1    Kammerer, B.2    Handrick, R.3    Eldh, T.4    Gruber, C.5    Cordes, N.6
  • 48
    • 70349579537 scopus 로고    scopus 로고
    • Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonine
    • Noureini SK, Wink M. Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonine. World J Gastroenterol 2009;15:3603-10.
    • (2009) World J Gastroenterol , vol.15 , pp. 3603-3610
    • Noureini, S.K.1    Wink, M.2
  • 49
    • 34548357033 scopus 로고    scopus 로고
    • Ukrain modulates glial fibrillary acidic protein, but not connexin 43 expression, and induces apoptosis in human cultured glioblastoma cells
    • DOI 10.1097/CAD.0b013e32808bf9ec, PII 0000181320070700000006
    • Gagliano N, Moscheni C, Torri C, Donetti E, Magnani I, Costa F, et al. Ukrain modulates glial fibrillary acidic protein, but not connexin 43 expression, and induces apoptosis in human cultured glioblastoma cells. Anticancer Drugs 2007;18:669-76. (Pubitemid 47343659)
    • (2007) Anti-Cancer Drugs , vol.18 , Issue.6 , pp. 669-676
    • Gagliano, N.1    Moscheni, C.2    Torri, C.3    Donetti, E.4    Magnani, I.5    Costa, F.6    Nowicky, W.7    Gioia, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.