Ceramide-induced apoptosis of D283 medulloblastoma cells requires mitochondrial respiratory chain activity but occurs independently of caspases and is not sensitive to Bcl-xL overexpression

Journal of Neurochemistry

Volumn 82, Issue 3, 2002, Pages 482-494

  Poppe, Monika ^a   Reimertz, Claus ^a   Münstermann, Gudrun ^a   Kögel, Donat ^a   Prehn, Jochen H M ^a,b  

^a Research Group Apoptosis and Cell Death   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Apoptosis; Bax; Bcl xL; Calpains; Caspases; Ceramide; Mitochondria

Indexed keywords

CALPAIN; CASPASE; CERAMIDE; CERAMIDE DERIVATIVE; MITOCHONDRIAL DNA; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN BAX; PROTEIN BCL XL; ROTENONE; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL STRUCTURE; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MEDULLOBLASTOMA; MITOCHONDRIAL RESPIRATION; NERVE CELL NECROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN;

APOPTOSIS; BCL-X PROTEIN; CALPAIN; CASPASES; CELL DEATH; CERAMIDES; CHROMATIN; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX IV; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUCOSE; HUMANS; MEDULLOBLASTOMA; MITOCHONDRIA; MULTIENZYME COMPLEXES; OXIDOREDUCTASES; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRUVIC ACID; SPHINGOSINE; SUCCINATE DEHYDROGENASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036320424     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.01007.x     Document Type: Article

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