Chitosan nanoparticles enhance the plasma exposure of (-)-epigallocatechin gallate in mice through an enhancement in intestinal stability

European Journal of Pharmaceutical Sciences

Volumn 44, Issue 3, 2011, Pages 422-426

  Dube, Admire ^a   Nicolazzo, Joseph A ^a   Larson, Ian ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

( ) Epigallocatechin gallate (EGCG); Chitosan tripolyphosphate nanoparticles (CS NPs); Intestinal stability; Oral absorption; Plasma exposure

Indexed keywords

CHITOSAN; EPIGALLOCATECHIN GALLATE; NANOPARTICLE;

AREA UNDER THE CURVE; ARTICLE; DRUG ABSORPTION; DRUG BLOOD LEVEL; INTESTINE ABSORPTION; JEJUNUM; MAXIMUM PLASMA CONCENTRATION; MOUSE; NANOENCAPSULATION; NONHUMAN; PRIORITY JOURNAL; STOMACH; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; CATECHIN; CHITOSAN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; INTESTINAL ABSORPTION; JEJUNUM; MALE; MICE; MOLECULAR STRUCTURE; MOUTH MUCOSA; NANOPARTICLES; STOMACH; TISSUE DISTRIBUTION;

EID: 80053931496     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.09.004     Document Type: Article

References (47)

1. A.J. Bailer Testing for the equality of area under the curves when using destructive measurement techniques Journal of Pharmacokinetics and Pharmacodynamics 16 3 1988 303 309
2. D.A. Balentine, and S.A. Wiseman The chemistry of tea flavonoids Critical Reviews in Food Science and Nutrition 37 8 1997 693 704 (Pubitemid 127349613)
3. G. Barratt Colloidal drug carriers: achievements and perspectives Cellular and Molecular Life Sciences (CMLS) 60 1 2003 21 37 (Pubitemid 36223115)
4. Y. Cai, and N.D. Anavy Contribution of presystemic hepatic extraction to the low oral bioavailability of green tea catechins in rats Drug Metabolism and Disposition 30 11 2002 1246 1249 (Pubitemid 35265832)
5. I.L.C. Chapple Reactive oxygen species and antioxidants in inflammatory diseases Journal of Clinical Periodontology 24 5 1997 287 296 (Pubitemid 127731526)
6. L. Chen, and M.-J. Lee Absorption, distribution, and elimination of tea polyphenols in rats Drug Metabolism and Disposition 25 9 1997 1045 1050 (Pubitemid 27396491)
7. H.-H.S. Chow, and I.A. Hakim Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of polyphenon E in healthy individuals Clinical Cancer Research 11 12 2005 4627 4633 (Pubitemid 40825654)
8. C. Damgé, and P. Maincent Oral delivery of insulin associated to polymeric nanoparticles in diabetic rats Journal of Controlled Release 117 2 2007 163 170 (Pubitemid 46161872)
9. A. Dube, and K. Ng Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution Food Chemistry 122 3 2010 662 667
10. A. Dube, and J.A. Nicolazzo Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (-)-epigallocatechin gallate European Journal of Pharmaceutical Sciences 41 2 2010 219 225
11. A. Dube, and J.A. Nicolazzo Assessment of plasma concentrations of (-)-epigallocatechin gallate in mice following administration of a dose reflecting consumption of a standard green tea beverage Food Chemistry 128 1 2011 7 13
12. A.T. Florence, and N. Hussain Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas Advanced Drug Delivery Reviews 50 Supplement 1 2001 S69 S89 (Pubitemid 32905356)
13. A.T. Florence, and A.M. Hillery Nanoparticles as carriers for oral peptide absorption: studies on particle uptake and fate Journal of Controlled Release 36 1-2 1995 39 46
14. R. Hackman, and J. Polagruto Flavanols: digestion, absorption and bioactivity Phytochemistry Reviews 7 1 2008 195 208 (Pubitemid 350233986)
15. H.-Y. Ho, and M.-L. Cheng Antiviral Effect of Epigallocatechin Gallate on Enterovirus 71 Journal of Agricultural and Food Chemistry 57 14 2009 6140 6147
16. C. Huo, and S. Wan The challenge of developing green tea polyphenols as therapeutic agents Inflammopharmacology 16 5 2008 248 252
17. T. Kuzuhara, and M. Suganuma Green tea catechin as a chemical chaperone in cancer prevention Cancer Letters 261 1 2008 12 20
18. W.H. Lam, and A. Kazi A potential prodrug for a green tea polyphenol proteasome inhibitor: evaluation of the peracetate ester of (-)-epigallocatechin gallate [(-)-EGCG] Bioorganic & Medicinal Chemistry 12 21 2004 5587 5593 (Pubitemid 39304058)
19. J.D. Lambert, and C.S. Yang Mechanisms of Cancer Prevention by Tea Constituents Journal of Nutrition 133 10 2003 3262S 3267S (Pubitemid 37222254)
20. J.D. Lambert, and M.-J. Lee Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice Journal of Nutrition 133 12 2003 4172 4177 (Pubitemid 37505494)
21. J.D. Lambert, and J. Hong Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice The Journal of Nutrition 134 8 2004 1948 1952 (Pubitemid 39031322)
22. J.D. Lambert, and M.-J. Lee Dose-dependent levels of Epigallocatechin-3- gallate in human colon cancer cells and mouse plasma and tissues Drug Metabolism and Disposition 34 1 2006 8 11 (Pubitemid 43042639)
23. J.D. Lambert, and S. Sang Peracetylation as a means of enhancing in-vitro bioactivity and bioavailability of epigallocatechin-3-gallate Drug Metabolism and Disposition 34 12 2006 2111 2116 (Pubitemid 44837773)
24. J.D. Lambert, and S.-J. Kwon Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate Carcinogenesis 29 10 2008 2019 2024
25. L.-C. Lin, and M.-N. Wang Pharmacokinetics of (-)-epigallocatechin-3- gallate in conscious and freely moving rats and its brain regional distribution Journal of Agricultural and Food Chemistry 55 4 2007 1517 1524
26. T. Luo, and J. Wang (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma Breast Cancer Research 12 1 2010 R8
27. M.C. Matuschek, and W.H. Hendriks The jejunum is the main site of absorption for anthocyanins in mice The Journal of Nutritional Biochemistry 17 1 2006 31 36 (Pubitemid 41774403)
28. X. Meng, and S. Sang Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats Chemical Research in Toxicology 15 8 2002 1042 1050 (Pubitemid 34977270)
29. D.G. Nagle, and D. Ferreira Epigallocatechin-3-gallate (EGCG): Chemical and biomedical perspectives Phytochemistry 67 17 2006 1849 1855 (Pubitemid 44291411)
30. J.R. Nedelman, and E. Gibiansky Applying Bailer's method for AUC confidence intervals to sparse sampling Pharmaceutical Research 12 1 1995 124 128
31. B.I. Polentarutti, and A.L. Peterson Evaluation of viability of excised rat intestinal segments in the Ussing Chamber: Investigation of morphology, electrical parameters, and permeability characteristics Pharmaceutical Research 16 3 1999 446 454 (Pubitemid 29162105)
32. D. Porath, and C. Riegger Epigallocatechin-3-gallate impairs chemokine production in human colon epithelial cell lines Journal of Pharmacology and Experimental Therapeutics 315 3 2005 1172 1180 (Pubitemid 41635405)
33. V.G. Raneva, and Y. Shimizu Antioxidant activity in plasma and tissue distribution of (-)-epigallocatechin gallate after oral administration to rats Journal of Oleo Science 54 5 2005 289 298
34. B. Sarmento, and A. Ribeiro Oral bioavailability of insulin contained in polysaccharide nanoparticles Biomacromolecules 8 10 2007 3054 3060 (Pubitemid 350011625)
35. A. Scalbert, and G. Williamson Dietary intake and bioavailability of polyphenols The Journl of Nutrition 130 2000 2073S 2085S (Pubitemid 30619386)
36. A. Scheepens, and K. Tan Improving the oral bioavailability of beneficial polyphenols through designed synergies Genes & Nutrition 5 1 2009 75 87
37. R.H. Stephens, and J. Tanianis-Hughes Region-dependent modulation of intestinal permeability by drug efflux transporters: In-vitro studies in mdr1a(-/-) mouse intestine The Journal of Pharmacology and Experimental Therapeutics 303 3 2002 1095 1101 (Pubitemid 35424394)
38. H. Wang, and G.J. Provan Tea flavonoids: their functions, utilisation and analysis Trends in Food Science & Technology 11 4-5 2000 152 160 (Pubitemid 32122540)
39. Wang, X., Wang, Y.-W., et al. (2009). Enhancing stability and oral bioavailability of polyphenols using nanoemulsions. Micro/Nanoencapsulation of Active Food Ingredients. Washington, DC, American Chemical Society: 198-212.
40. G.G. Williamson Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies The American Journal of Clinical Nutrition 81 1S 2005 243S
41. H. Yang, and R. Finaly Alteration in epithelial permeability and ion transport in a mouse model of total parenteral nutrition Critical Care Medicine 31 4 2003 1118 1125 (Pubitemid 36444423)
42. C.S. Yang, and S. Sang Bioavailability issues in studying the health effects of plant polyphenolic compounds Molecular Nutrition & Food Research 52 S1 2008 S139 S151
43. J. Yuan Estimation of variance for AUC in animal studies Journal of Pharmaceutical Sciences 82 7 1993 761 763 (Pubitemid 23315700)
44. N.T. Zaveri Green tea and its polyphenolic catechins: medicinal uses in cancer and noncancer applications Life Sciences 78 18 2006 2073 2080
45. L. Zhang, and Y. Zheng Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model International Journal of Pharmaceutics 287 1-2 2004 1 12 (Pubitemid 39487237)
46. Q.Y. Zhu, and A. Zhang Stability of green tea catechins Journal of Agricultural and Food Chemistry 45 12 1997 4624 4628 (Pubitemid 127485815)
47. M. Zhu, and Y. Chen Oral absorption and bioavailability of tea catechins Planta Medica 66 5 2000 444 447 (Pubitemid 30413506)