Region-dependent modulation of intestinal permeability by drug efflux transporters: In vitro studies in mdr1a(-/-) mouse intestine

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 3, 2002, Pages 1095-1101

  Stephens, R H ^a   Tanianis Hughes, J ^a   Higgs, N B ^a   Humphrey, M ^b   Warhurst, G ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PROPRANOLOL;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CONTROLLED STUDY; DESCENDING COLON; DRUG PENETRATION; DRUG TRANSPORT; GENE DELETION; ILEUM; IN VITRO STUDY; INTESTINE MUCOSA PERMEABILITY; JEJUNUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; COLON; DIGOXIN; ILEUM; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; JEJUNUM; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; P-GLYCOPROTEINS; PACLITAXEL; PERMEABILITY; PROPRANOLOL;

EID: 0036896380     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.041236     Document Type: Article

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