The VPAC 2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1 G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a

FASEB Journal

Volumn 25, Issue 10, 2011, Pages 3674-3686

  Goursaud, Stéphanie ^a   Focant, Marylène C ^a   Berger, Julie V ^a   Nizet, Yannick ^a   Maloteaux, Jean Marie ^a   Hermans, Emmanuel ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Astrocytes; Neurodegenerative disease; Splice variants; White matter

Indexed keywords

CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMATE TRANSPORTER; GLUTAMATE TRANSPORTER 1A; GLUTAMATE TRANSPORTER 1B; GLUTAMIC ACID; MESSENGER RNA; PEPTIDE HISTIDINE ISOLEUCINE; UNCLASSIFIED DRUG; EXCITATORY AMINO ACID TRANSPORTER 2; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID DERIVATIVE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN PROTEIN; SUPEROXIDE DISMUTASE; VASOACTIVE INTESTINAL POLYPEPTIDE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CORPUS CALLOSUM; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INACTIVATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSGENIC RAT; UPREGULATION; ANIMAL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TRANSGENIC ANIMAL; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA; RATTUS;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BIOLOGICAL TRANSPORT; CASPASE 3; CORPUS CALLOSUM; EXCITATORY AMINO ACID TRANSPORTER 2; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATES; MYELIN PROTEINS; PEPTIDE PHI; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; SUPEROXIDE DISMUTASE; VASOACTIVE INTESTINAL PEPTIDE;

EID: 80053929482     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-182337     Document Type: Article

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