Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis

Biochemical Pharmacology

Volumn 70, Issue 12, 2005, Pages 1744-1755

  Hinoi, Eiichi ^a   Ohashi, Ryosuke ^a   Miyata, Susumu ^b   Kato, Yasuko ^b   Iemata, Mika ^a   Hojo, Hironori ^a   Takarada, Takeshi ^a   Yoneda, Yukio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b ASTELLAS PHARMA INC   (Japan)

Author keywords

3H glutamate accumulation; Cell proliferation; EAATs; GluRs; Glutamate; Rheumatoid arthritis; Synovial fibroblasts

Indexed keywords

AMINO ACID TRANSPORTER; BROXURIDINE; COLLAGEN; COLLAGEN TYPE 2; CYTOKINE; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMATE RECEPTOR; GLUTAMATE TRANSPORTER; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST CULTURE; GENE EXPRESSION; HISTOLOGY; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; KNEE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RHEUMATOID ARTHRITIS; STATISTICAL SIGNIFICANCE; SYNOVIOCYTE; SYNOVIUM; TEMPERATURE DEPENDENCE;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CELLS, CULTURED; CYTOKINES; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; EXCITATORY AMINO ACID TRANSPORTER 3; FIBROBLASTS; GLUTAMIC ACID; MALE; RATS; RATS, INBRED LEW; RNA, MESSENGER; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE;

EID: 27744595535     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.09.010     Document Type: Article

References (44)

1. M. Feldmann Pathogenesis of arthritis: recent research progress Nat Immunol 2 2001 771 773
2. G.S. Firestein Evolving concepts of rheumatoid arthritis Nature 423 2003 356 361
3. P.H. Wooley, H.S. Luthra, J.M. Stuart, and C.S. David Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates J Exp Med 154 1981 688 700
4. T. Sasakawa, Y. Sasakawa, Y. Ohkubo, and S. Mutoh FK506 ameliorates spontaneous locomotor activity in collagen-induced arthritis: implication of distinct effect from suppression of inflammation Int Immunopharmacol 5 2005 503 510
5. T. McNearney, D. Speegle, N. Lawand, J. Lisse, and K.N. Westlund Excitatory amino acid profiles of synovial fluid from patients with arthritis J Rheumatol 27 2000 739 745
6. N.B. Lawand, T. McNearney, and K.N. Westlund Amino acid release into the knee joint: key role in nociception and inflammation Pain 86 2000 69 74
7. T. McNearney, B.A. Baethge, S. Cao, R. Alam, J.R. Lisse, and K.N. Westlund Excitatory amino acids, TNF-alpha, and chemokine levels in synovial fluids of patients with active arthropathies Clin Exp Immunol 137 2004 621 627
8. M. Hollmann, A. O′Shea-Greenfield, S.W. Rogers, and S. Heinemann Cloning by functional expression of a member of the glutamate receptor family Nature 342 1989 643 648
9. Y. Yoneda, N. Kuramoto, T. Kitayama, and E. Hinoi Consolidation of transient ionotropic glutamate signals through nuclear transcription factors in the brain Prog Neurobiol 63 2001 697 719
10. W. Wisden, and P.H. Seeburg Mammalian ionotropic glutamate receptors Curr Opin Neurobiol 3 1993 291 298
11. M. Hollmann, and S. Heinemann Cloned glutamate receptors Ann Rev Neurosci 17 1994 31 108
12. M. Masu, Y. Tanabe, K. Tsutida, R. Shigemoto, and S. Nakanishi Sequence and expression of a metabotropic glutamate receptor Nature 349 1991 760 765
13. Y. Tanabe, M. Masu, T. Ishii, R. Shigemoto, and S. Nakanishi A family of metabotropic glutamate receptors Neuron 8 1992 169 179
14. N.C. Danbolt Glutamate uptake Prog Neurobiol 65 2001 1 105
15. Y. Kanai, and M.A. Hediger The glutamate and neutral amino acid transporter family: physiological and pharmacological implications Eur J Pharmacol 479 2003 237 247
16. T.M. Skerry, and P.G. Genever Glutamate signalling in non-neuronal tissues Trend Pharmacol Sci 22 2001 174 181
17. E. Hinoi, T. Takarada, T. Ueshima, Y. Tsuchihashi, and Y. Yoneda Glutamate signaling in peripheral tissues Eur J Biochem 271 2004 1 13
18. E. Hinoi, L. Wang, A. Takemori, and Y. Yoneda Functional expression of particular isoforms of excitatory amino acid transporters by rodent cartilage Biochem Pharmacol 70 2005 70 81 (equally contributed)
19. D.E. Trentham, A.S. Townes, and A.H. Kang Autoimmunity to type II collagen an experimental model of arthritis J Exp Med 146 1977 857 868
20. T. Takarada, E. Hinoi, V.J. Balcar, H. Taniura, and Y. Yoneda Possible expression of functional glutamate transporters in the rat testis J Endocrinol 181 2004 233 244
21. 3H]glutamate in cultured rat calvarial osteoblasts Biochem Pharmacol 68 2004 177 184
22. C. Vermeiren, M. Najimi, J.M. Maloteaux, and E. Hermans Molecular and functional characterization of glutamate transporters in rat cortical astrocytes exposed to a defined combination of growth factors during in vitro differentiation Neurochem Int 46 2005 137 147
23. L. Raiteri, S. Stigliani, L. Patti, C. Usai, G. Bucci, and A. Diaspro Activation of gamma-aminobutyric acid GAT-1 transporters on glutamatergic terminals of mouse spinal cord mediates glutamate release through anion channels and by transporter reversal J Neurosci Res 80 2005 424 433
24. L. Atkinson, T.F. Batten, T.S. Moores, H. Varoqui, J.D. Erickson, and J. Deuchars Differential co-localisation of the P2X7 receptor subunit with vesicular glutamate transporters VGLUT1 and VGLUT2 in rat CNS Neuroscience 123 2004 761 768
25. J. Huggett, A. Vaughan-Thomas, and D. Mason The open reading frame of the Na(+)-dependent glutamate transporter GLAST-1 is expressed in bone and a splice variant of this molecule is expressed in bone and brain FEBS Lett 485 2000 13 18
26. P. Reye, R. Sullivan, H. Scott, and D.V. Pow Distribution of two splice variants of the glutamate transporter GLT-1 in rat brain and pituitary Glia 38 2002 246 255
27. A. Gadea, and A.M. Lopez-Colome Glial transporters for glutamate, glycine and GABA: I. Glutamate transporters J Neurosci Res 63 2001 453 460
28. E. Hinoi, T. Takarada, Y. Tsuchihashi, and Y. Yoneda Glutamate transporters as drug targets Curr Drug Targets CNS Neurol Dis 4 2005 211 220
29. S. Bannai Exchange of cystine and glutamate across plasma membrane of human fibroblasts J Biol Chem 261 1986 2256 2263
30. H. Sato, M. Tamba, T. Ishii, and S. Bannai Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins J Biol Chem 274 1999 11455 11458
31. S. Kato, K. Negishi, K. Mawatari, and C.H. Kuo A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion Neuroscience 48 1992 903 914
32. H. Sato, K. Fujiwara, J. Sagara, and S. Bannai Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide Biochem J 310 1995 547 551
33. D.M. Bukowski, S.M. Deneke, R.A. Lawrence, and S.G. Jenkinson A noninducible cystine transport system in rat alveolar type II cells Am J Physiol Lung Cell Mol Physiol 268 1995 L21 L26
34. R.G. Knickelbein, T. Seres, G. Lam, R.B. Johnston Jr., and J.B. Warshaw Characterization of multiple cysteine and cystine transporters in rat alveolar type II cells Am J Physiol Lung Cell Mol Physiol 273 1997 L1147 L1155
35. A.S. Bender, W. Reichelt, and M.D. Norenberg Characterization of cystine uptake in cultured astrocytes Neurochem Int 37 2000 269 276
36. C.I. Lin, I. Orlov, A.M. Ruggiero, M. Dykes-Hoberg, A. Lee, and M. Jackson Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18 Nature 410 2001 84 88
37. M. Jackson, W. Song, M.Y. Liu, L. Jin, M. Dykes-Hoberg, and C.I. Lin Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins Nature 410 2001 89 93
38. G.R. Burmester, A. Dimitriu-Bona, S.J. Waters, and R.J. Winchester Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts Scand J Immunol 17 1983 69 82
39. H. Takayanagi, H. Oda, S. Yamamoto, H. Kawaguchi, S. Tanaka, and T. Nishikawa A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis Biochem Biophys Res Commun 240 1997 279 286
40. T. Zimmermann, E. Kunisch, R. Pfeiffer, A. Hirth, H.D. Stahl, and U. Sack Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture - primary culture cells markedly differ from fourth-passage cells Arthritis Res 3 2001 72 76
41. H. Seto, S. Kamekura, T. Miura, A. Yamamoto, H. Chikuda, and T. Ogata Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts J Clin Invest 113 2004 718 726
42. P.P. Tak, and B. Bresnihan The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis Arthritis Rheum 43 2000 2619 2633
43. L.C. Hofbauer, and A.E. Heufelder The role of osteoprotegerin and receptor activator of nuclear factor kappaB ligand in the pathogenesis and treatment of rheumatoid arthritis Arthritis Rheum 44 2001 253 259
44. M. Kaneko, T. Tomita, T. Nakase, Y. Ohsawa, H. Seki, and E. Takeuchi Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis Rheumatology (Oxford) 40 2001 247 255