Flavonoids and oxidative stress in Drosophila melanogaster

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 726, Issue 1, 2011, Pages 60-65

  Sotibrán, América Nitxin Castañeda ^a   Ordaz Téllez, María Guadalupe ^a   Rodríguez Arnaiz, Rosario ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antioxidant capacities; Flavonoids; Oxidative stress; Wing somatic assay of Drosophila melanogaster

Indexed keywords

CELL MARKER; CHLOROGENIC ACID; FLAVONOID; HYDROGEN PEROXIDE; KAEMPFEROL; PARAQUAT; POLYPHENOL; QUERCETIN; QUERCETIN 3 BETA DEXTRO GLYCOSIDE; QUERCETIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE MUTATION; GENOTOXICITY; LARVA; MITOTIC RECOMBINATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SOMATIC MUTATION;

ANIMALS; ANTIOXIDANTS; DROSOPHILA MELANOGASTER; FLAVONOIDS; HYDROGEN PEROXIDE; MUTAGENICITY TESTS; MUTAGENS; OXIDATIVE STRESS; POLYPHENOLS;

DROSOPHILA MELANOGASTER;

EID: 80053634780     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.08.005     Document Type: Article

References (58)

1. Harborne J.B. Plant phenolics. Encyclopedia of Plant Physiology, Secondary Plant Products 1980, vol. 8:329-395. Berlin Heidelberg, New York, Springer-Verlag.
2. Cotelle N. Role of flavonoids in oxidative stress. Curr. Top. Med. Chem. 2001, 1:569-590.
3. Duthie G., Crozier A. Plant-derived phenolic antioxidants. Curr. Opin. Lipidol. 2000, 11:43-47.
4. Crozier A., Burns J., Aziz A.A., Stewart A.J., Rabiasz H.S., Jenkins G.I., Edwards C.A., Lean M. Antioxidant flavonols from fruits, vegetables and beverages: measurements and bioavailability. Biol. Res. 2000, 33:79-88.
5. Bravo L. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nut. Rev. 1998, 56:317-333.
6. Nagao M., Morita N., Yahagi T., Shimizu M., Kuroyanagi M., Fukuoka M., Yoshihira K., Natori S., Fujino T., Sugimura T. Mutagenicities of 61 flavonoids and 11 related compounds. Environ. Mutagen. 1981, 3:401-404.
7. Elliger G.A., Henika P.R., Mc Gregor J.T. Mutagenicity of flavones, chromones and acetophenones in Salmonella typhimurium. New structure-activity relationships. Mutat. Res. 1984, 135:77-86.
8. Zhu B.T., Lier J.G. Quercetin increases the severity of estradiol-induced tumorigenesis in hamster kidney. Toxicol. Appl. Pharmacol. 1994, 125:149-158.
9. Rhaman A., Hadi S.M., Parish J.H., Ainsley K. Strand scission in DNA induced by quercetin and Cu(II): role of Cu(I) and oxygen free radicals. Carcinogenesis 1989, 10:1833-1839.
10. Said Ahmad M., Fazal F., Rahman A., Hadi S.M., Parish JH J.H. Activities of flavonoids for the cleavage of DNA in the presence of Cu(II): correlation with generation of active oxygen species. Carcinogenesis 1992, 13:605-608.
11. Cao G., Sofic E., Prior R.L. antioxidant and prooxidant behavior of flavonoids: structure-activity relationship. Free Radic. Biol. Med. 1997, 22:749-760.
12. Lamoral-Theys D., Pottier L., Dufrasne F., Nève J., Dubois J., Kornienko A., Kiss R., Ingrassia L. Natural polyphenols that display anticancer properties through inhibition of kinase activity. Curr. Med. Chem. 2010, 17:812-825.
13. Benthsath A., Rusznyak S., Szent-György A. Vitamin nature of flavones. Nature 1936, 138:798.
14. Benthsath A., Rusznyak S., Szent-György A., Vitamin P. Nature 1937, 139:326.
15. Rusznyak S., Szent-György A., Vitamin P. Flavonols as vitamins, nature of flavones. Nature 1936, 138:27.
16. Duthie S.J., Johnson W., Dobson V.L. The effects of dietary flavonoids on DNA damage (strand breaks and oxidised pyrimidines) and growth in human cells. Mutat. Res. 1997, 390:141-151.
17. Jovanovic S.V., Steenken S., Simic M.G., Hara Y. Antioxidant properties of flavonoids: reduction potentials and electron transfer reactions of flavonoid radicals. Flavonoids in Health and Disease 1998, 137-161. Marcel Decker, New York. C. Rice-Evans, L. Packer (Eds.).
18. Musonda C.A., Chipman J.K. Quercetin inhibits hydrogen peroxide-induced NF-kappaB DNA binding activity and DNA damage in HepG2 cells. Carcinogenesis 1998, 19:1583-1589.
19. Tsai S.H., Lin-Shiau S., Lin J.K. Suppression of nitric oxide synthase and the down-regulation of the activation of NF-kappaB in macrophages by resveratrol. Br. J. Pharmacol. 1999, 126:673-680.
20. Manthey J.A., Grohmann K., Montanari A., Ash K., Manthey C.L. Polymethoxylated flavones derived from citrus suppress tumour necrosis factor-alpha expression in human monocytes. J. Nat. Prod. 1999, 62:441-444.
21. Gerritsen M.E., Carley W.W., Ranges G.E., Shen C.P., Phan S.A., Ligon G.F., Perry C.A. Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression. Am. J. Pathol. 1995, 147:278-292.
22. Panes J., Gerritsen M.E., Anderson D.C., Miyasaka M., Granger D.M. Apigenin inhibits tumour necrosis factor-induced intercellular adhesion molecule-1upregulation in vivo. Microcirculation 1996, 3:279-286.
23. Soriani M., Rice-Evans C.A., Tyrrell R.M. Modulation of the UVA activation of haem oxygenase, collagenase and cyclooxygenase gene expression by epigallocatecgin in human skin cells. FEBS Lett. 1998, 439:253-257.
24. Youdim K.A., Martin A., Joseph J.A. Incorporation of the elderberry anthocyanins by endothelial cells increases protection against oxidative stress. Free Radic. Biol. Med. 2000, 29:51-60.
25. Sestili P., Guidarelli A., Dacha M., Cantoni O. Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. Free Radic. Biol. Med. 1998, 25:196-200.
26. Mori H., Tanaka T., Shima H., Kunniyasu T., Takahashi M. Inhibitory effect of chlorogenic acid on methlazoxymethanol acetate-induced carcinogenesis in large intestine and liver of hamsters. Cancer Lett. 1986, 30:49-50.
27. Tanaka T., Kojima T., Kawamori T., Wang A., Suzui M., Okamoto K., Mori H. Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by the naturally occurring plant phenolics caffeic, ellagic, chlorogenic and ferulic acids. Carcinogenesis 1993, 14:1321-1325.
28. Tsuchiya T., Suzuki O., Igarashi K. Protective effects of chlorogenic acid on paraquat-induced oxidative stress in rats. Biosci. Biotechnol. Biochem. 1996, 60:765-768.
29. Soucek P., Kondrova E., Hermanek J., Stopka P., Boumendjel A., Ueng Y.F., Gut I. New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals. Anticancer Drugs 2011, 22:176-184.
30. Nirmala P., Ramanathan M. Effect of kaempferol on lipid peroxidation and antioxidant status in 1,2-dimethyl hydrazine induced colorectal carcinoma in rats. Eur. J. Pharmacol. 2011, 654:75-79.
31. Lindsley D.L., Zimm G.G. The Genome of Drosophila melanogaster 1992, Academic Press, San Diego.
32. Graf U., Würgler F., Katz A., Frei H., Juon H., Hall C., Kale P. Somatic mutation and recombination test in Drosophila melanogaster. Environ. Mutagen. 1984, 6:153-188.
33. Frei H., Würgler F.E. Statistical methods to decide whether mutagenicity test data from Drosophila assays indicate a positive, negative or inconclusive result. Mutat. Res. 1988, 203:297-308.
34. Frei H., Würgler F.E. Optimal experimental design and sample size for the statistical evaluation of data from somatic mutation and recombination test (SMART) in Drosophila. Mutat. Res. 1995, 334:247-258.
35. Rietjens I.M.C.M., Boersma M.G., van der Woude H., Jeurissen S.M.F., Schutte M.E., Alink G.M. Flavonoids and alkenbenzenes: mechanisms of mutagenic action and carcinogenic risk. Mutat. Res. 2005, 574:124-128.
36. Stich H.F., Rosin M.P., Wu C.H., Powrie W.D. A comparative genotoxicity study of chlorogenic acid (3-0-caffeoylquinic acid). Mutat. Res. 1981, 90:201-212.
37. MacGregor J.T., Jurd L. Mutagenicity of plant flavonoids: structural Requirements for mutagenic activity in Salmonella typhimurium. Mutat. Res. 1978, 54:297-309.
38. Hardigree A.A., Epler J.L. Comparative mutagenesis of plant flavonoids in microbial systems. Mutat. Res. 1978, 58:231-239.
39. Watson W.A.F. The mutagenicity of quercetin and kaempferol in Drosophila melanogaster. Mutat. Res. 1982, 103:145-147.
40. Carver J.H., Carrano A.V., MacGregor J.T. Genetic effects of the flavonols quercetin kaempferol, and galangin on Chinese hamster ovary cells in vitro. Mutat. Res. 1983, 113:45-60.
41. Silva I.D., Rodrigues A.S., Gaspar J., Maia R., Laires A., Rueff J. Involvement of rat cytochrome 1A1 in the biotransformation of kaempferol to quercetin: relevance to the genotoxicity of kaempferol. Mutagenesis 1997, 12:383-390.
42. MacGregor J.T., Wehr C.M., Manners G.D., Jurd L., Minkler J.L., Carrano A.V. Influence on frequencies of micronuclei in mouse erythrocytes and sister chromatid exchange in rabbit lymphocytes. Mutat. Res. 1983, 124:255-270.
43. Brown J.B., Dietrich P.S. Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test. Activation of flavonol glycosides by mixed glycosidases from rat cecal bacteria and other sources. Mutat. Res. 1979, 66:223-240.
44. Rueff J., Laires A., Borba H., Chaveca T., Gomes M.I., Halpern M. Genetic toxicology of flavonoids: the role of metabolic conditions in the induction of reverse mutation, SOS functions and sister chromatid exchanges. Mutagenesis 1986, 1:179-183.
45. Gaspar J., Rodrigues A., A.Laires A., Silva F., Costa S., Monteiro M.J., Monteiro C., Rueff J. On the mechanisms of genotoxicity and metabolism of quercetin. Mutagenesis 1994, 9:445-449.
46. da Silva J., Herrmann S.M., Heuser V., Peres W., Possa Marroni N., González-Gallego J., Erdtmann B. Evaluation of the genotoxic effect of rutin and quercetin by comet assay and micronucleus test. Food Chem. Toxicol. 2002, 40:941-947.
47. Castañeda S.A.N., Ordaz T.M.G., Andrade-Cetto A., Segal Kischinevzky C., Rodríguez-Arnaiz R. Antimutagenic activity of two medicinal phytoextracts in somatic cells of Drosophila melanogaster. Pharm. Biol. 2011, 49:640-647.
48. Halliwell B., Gutteridge J.M. Free Radicals in Biology and Medicine 1989, Oxford University Press, New York.
49. Hou L., Zhou B., Yang L., Liu Z.L. Inhibition of free radical initiated peroxidation of human erythrocyte ghosts by flavonols and their glycosides. Org. Biomol. Chem. 2004, 2:1419-1423.
50. Li S., Crooks P.A., Wei X., de Leon J. Toxicity of dipyridyl compounds and related compounds. Crit. Rev. Toxicol. 2004, 34:447-460.
51. WHO, The World Health Organization Recommended Classification of Pesticides by Hazard and Guidelines to Classification, Geneva, 2005. Available from: http://www.who.int/ipcs/publications/pesticides_hazard/en/.
52. Kral J., Bagley A.C., Mullenbach G.T., Hallewell R.A., Lynch R.E. Superoxide mediates the toxicity of paraquat for cultured mammalian cells. J. Biol. Chem. 1988, 263:1910-1914.
53. Mollace V., Iannone M., Muscoli C., Palma E., Granato T., Rispoli V., Nistico R., Rotiroti D., Salvemini D. The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non-peptidyl superoxide dismutase mimetic. Neurosci. Lett. 2003, 335:163-166.
54. Suntres Z.E. Role of antioxidants in paraquat toxicity. Toxicology 2002, 180:65-77.
55. Gaivão I., Sierra L.M., Comendador M.A. The w/w+ SMART assay of Drosophila melanogaster detects the genotoxic effects of reactive oxygen species inducing compounds. Mutat. Res. 1999, 440:139-145.
56. Narayana K., D'souza U.J., Rao K.P. Ribavirin-induced sperm shape abnormalities in Wistar rat. Mutat. Res. 2002, 513:193-196.
57. Limauro D., Pedone E., Pirone L., Bartolucci S. Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress. FEBS J. 2006, 273:721-731.
58. Prado R., García R., Rioboo C., Herrero C., Abalde J., Cid A. Comparison of the sensitivity of different toxicity test endpoints in a microalga exposed to the herbicide paraquat. Environ. Int. 2009, 35:240-247.