Structure and mechanism of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway

Biochemistry

Volumn 50, Issue 40, 2011, Pages 8603-8615

  He, Shu Mei ^a   Wathier, Matthew ^a   Podzelinska, Kateryna ^a   Wong, Matthew ^a   McSorley, Fern R ^a   Asfaw, Alemayehu ^a   Hove Jensen, Bjarne ^b   Jia, Zongchao ^a   Zechel, David L ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACID CATALYST; ACID RESIDUES; ACTIVE SITE RESIDUES; DIESTERS; KINETIC ANALYSIS; LACTAMASES; LEAVING GROUPS; LINEAR CORRELATION; MANGANESE IONS; METAL ION BINDING; ORGANOPHOSPHONATES; ORTHO-VANADATE; PH DEPENDENCE; PHOSPHATE ESTERS; PHOSPHODIESTERASES; PHOSPHORYL TRANSFER; SITE DIRECTED MUTAGENESIS; TETRAHEDRAL GEOMETRY; TRANSITION STATE; WILD-TYPE ENZYMES; X RAY STRUCTURAL ANALYSIS;

AMINO ACIDS; ENZYME INHIBITION; MANGANESE; METAL IONS; PHOSPHORUS; SPHERES;

ESTERS;

ACID; ALANINE; CARBON; H200 ACID; LYASE; MANGANESE; METAL ION; NICKEL; ORTHOVANADIC ACID; PHOSPHODIESTERASE; PHOSPHODIESTERASE PHNP; PHOSPHORUS; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME KINETICS; ENZYME STRUCTURE; NONHUMAN; PH; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; WILD TYPE; X RAY ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORIC DIESTER HYDROLASES; PROTEIN BINDING;

BACTERIA (MICROORGANISMS);

EID: 80053600609     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2005398     Document Type: Article

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