Balanced interactions between Lyn, the p85α Regulatory Subunit of Class I A phosphatidylinositol-3-kinase, and SHIP Are essential for mast cell growth and maturation

Molecular and Cellular Biology

Volumn 31, Issue 19, 2011, Pages 4052-4062

  Ma, Peilin ^a   Vemula, Sasidhar ^a   Munugalavadla, Veerendra ^a   Chen, Jinbiao ^a   Sims, Emily ^a   Borneo, Jovencio ^a   Kondo, Takako ^a   Ramdas, Baskar ^a   Mali, Raghuveer Singh ^a   Li, Shuo ^a   Hashino, Eri ^a   Takemoto, Clifford ^b   Kapur, Reuben ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE LYN; PROTEIN P85ALPHA; PROTEIN TYROSINE KINASE; SRC HOMOLOGY 2 CONTAINING INOSITOL 5 PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW DERIVED MAST CELL; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BONE MARROW CELLS; CARRIER PROTEINS; CHROMOSOMAL PROTEINS, NON-HISTONE; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-KIT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STEM CELL FACTOR;

EID: 80053596162     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.05750-11     Document Type: Article

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