Demonstration that human mast cells arise from a progenitor cell population that is CD34+, c-kit+, and expresses aminopeptidase N (CD13)

Blood

Volumn 94, Issue 7, 1999, Pages 2333-2342

  Kirshenbaum, Arnold S ^a   Goff, Julie P ^b   Semere, Tekli ^b   Foster, Barbara ^b   Scott, Linda M ^b   Metcalfe, Dean D ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; MICROSOMAL AMINOPEPTIDASE; STEM CELL FACTOR;

ANTIGEN EXPRESSION; ARTICLE; CELL LINEAGE; CELL PROLIFERATION; CELL SELECTION; CELL SPECIFICITY; GROWTH REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MAST CELL; PRIORITY JOURNAL;

EID: 0033215406     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.7.2333.419k30_2333_2342     Document Type: Article

References (36)

1. + bone marrow progenitor cells. J Immunol 146:1410, 1991
2. + cell population. Blood 84:2489, 1994
3. + cell populations in vitro by selectively supporting the viability of mast cells while internalizing and degrading basophils. Int Arch Allergy Immunol 105:374, 1994
4. Saito H, Ebisawa M, Tachimoto H, Schichijo M, Fukagawa K, Matsumoto K, Iikura Y, Awaji T, Tsujimoto G, Yanagida M, Uzumaki H, Takahashi G, Tsuji K, Nakahata T: Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells. J Immunol 157:343, 1996
5. + cord blood cells stimulated with stem cell factor and interleukin-3. Blood 84:3667, 1994
6. Okayama Y, Hunt TC, Kassel O, Ashman LK, Church MK: Assessment of the anti-c-kit monoclonal antibody YB5.B8 in affinity magnetic enrichment of human lung mast cells. J Immunol Methods 169:153, 1994
7. Willheim M, Agis H, Sperr WR, Koller M, Bankl H-C, Kiener H, Fritsch G, Fureder W, Spittler A, Graninger W, Scheiner O, Gadner H, Lechner K, Boltz-Nitulescu G, Valent P: Purification of human basophils and mast cells by multistep separation technique and mAB to CDw17 and CD117/c-kit. J Immunol Methods 182:115, 1995
8. Rodewald H-R, Dessing M, Dvorak AM, Galli SJ: Identification of a committed precursor for the mast cell lineage. Science 271:818, 1996
9. Valent P: The phenotype of human eosinophils, basophils and mast cells. J Allergy Clin Immunol 94:1177, 1994
10. Escribano L, Orfao A, Villarrubia J, Martin F, Madruga JI, Cuevas M, Velasco JL, Rios A, San Miguel JF: Sequential immunophenotypic analysis of mast cells in a case of systemic mast cell disease evolving to a mast cell leukemia. Cytometry 30:98, 1997
11. Chem H, Kinzer CA, Paul WE: P161, a murine membrane protein expressed on mast cells and some macrophages, is mouse CD13/aminopeptidase N. J Immunol 157:2593, 1996
12. Nilsson G, Forsberg K, Bodger MP, Ashman LK, Zsebo KM, Ishizaka T, Irani AM, Schwartz LB: Phenotypic characterization of stem cell factor-dependent human foetal liver-derived mast cells. Immunology 79:325, 1993
13. Stain C, Stockinger H, Scharf M, Jager U, Gossinger H, Lechner K, Bettelheim P: Human blood basophils display a unique phenotype including activation linked membrane structures. Blood 70:1872, 1987
14. Valent P, Ashman LK, Hinterberger W, Eckersberger F, Majdic O, Lechner K, Bettelheim P: Mast cell typing: Demonstration of a distinct hematopoietic cell type and evidence for immunophenotypic relationship to mononuclear phagocytes. Blood 73:1778, 1989
15. Agis H, Fureder W, Bankl HC, Kundi M, Sperr WR, Willheim M, Boltz-Nitulescu G, Butterfield JH, Kishi K, Lechner K, Valent P: Comparative immunophenotypic analysis of human mast cells, blood basophils and monocytes. Immunology 87:535, 1996
16. Valent P, Bettelheim P: Cell surface structures on human basophils and mast cells: Biochemical and functional characterization. Adv Immunol 52:333, 1992
17. Look AT, Ashmun RA, Shapiro LH, Peiper SC: Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J Clin Invest 83:1299, 1989
18. Civin C: Human monomyeloid cell membrane antigens. Exp Hematol 18:461, 1990
19. Kirshenbaum AS, Worobec AS, Davis TA, Goff JP, Semere T, Metcalfe DD: Inhibition of human mast cell growth and differentiation by interferon gamma-1b. Exp Hematol 26:245, 1998
20. Berardi AD, Wang A, Levine JD, Lopez P, Scadden DT: Functional isolation and characterization of human hematopoietic stem cells. Science 267:104, 1995
21. Kobayashi M, Laver JH, Kato T, Miyazaki H, Ogawa M: Thrombopoietin supports proliferation of human primitive hematopoietic cells in synergy with steel factor and/or interleukin-3. Blood 88:429, 1996
22. - hematopoietic stem cells. Blood 83:1515, 1994
23. Forni L: Reagents for immunofluorescence and their use for studying lymphoid cell products. Immunol Methods 8:151, 1979
24. Prussin C, Metcalfe DD: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods 182:115, 1995
25. Valent P, Spanblochl E, Sperr WR, Sillaber C, Zsebo KM, Agis H, Strobl H, Geissler K, Bettelheim P, Lechner K: Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture. Blood 80:2237, 1992
26. Irani A-M, Schechter NM, Craig SS, DeBlois G, Schwartz LB: Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci USA 83:4464, 1986
27. Bressler RB, Thompson HL, Keffer JM, Metcalfe DD: Inhibition of the growth of IL-3-dependent mast cells from murine bone marrow by recombinant granulocyte macrophage-colony stimulating factor. J Immunol 143:135, 1989
28. Du Z, Li Y, Xia H, Irani AM, Schwartz LB: Recombinant human granulocyte macrophage-colony stimulating factor (CSF), but not recombinant human granulocyte CSF, downregulates the recombinant human stem cell factor-dependent differentiation of human fetal liver-derived mast cells. J Immunol 159:838, 1997
29. Travis WD, Li CY, Hoagland HC, Travis LB, Banks PM: Mast cell leukemia: Report of a case and review of the literature. Mayo Clin Proc 61:957, 1986
30. Gurish MF, Friend DS, Webster M, Ghildyal N, Nicodemus CF, Stevens RL: Mouse mast cells that possess segmented/multi-lobular nuclei. Blood 90:382, 1997
31. Thompson HL, Metcalfe DD, Kinet JP: Early expression of high-affinity receptor for immunoglobulin E (Fcepsilon RI) during differentiation of mouse mast cells and human basophils. J Clin Invest 85:1227, 1990
32. Kanbe N, Kurosawa M, Miyachi Y, Kanbe M, Kempuraj D, Tachimoto H, Saito H: Carnoy's fixative reduces the number of chymase-positive cells in immunocytochemical staining of cord-blood-derived human cultured mast cells. Allergy 53:981, 1998
33. Lawrence JB, Friedman BS, Travis WD, Chinchilli VM, Metcalfe DD, Gralnick HR: Hematologic manifestations of systemic mast cell disease: A prospective study of laboratory and morphologic features and their relation to prognosis. Am J Med 91:612, 1991
34. Horny HP, Parwaresch MR, Lennert K: Bone marrow findings in systemic mastocytosis. Hum Pathol 16:808, 1985
35. Friedman B, Darling G, Norton J, Hamby L, Metcalfe D: Splenectomy in the management of systemic mast cell disease. Surgery 107:94, 1990
36. Kempuraj D, Saito H, Kaneko A, Fukagawa K, Nakayama M, Toru H, Tomikawa M, Tachimoto H, Ebisawa M, Akasawa A, Miyagi T, Kimura H, Nakajima T, Tsuji K, Nakahata T: Characterization of mast cell-committed progenitors present in human umbilical cord blood. Blood 93:3338, 1999